What do you do when there is no right answer, only the decision you can live with?

At 31 years old, days after an emergency C-section with her newborn in the NICU, Parul Samani felt a lump. Her husband wheeled her in a wheelchair to a neighboring hospital for a biopsy. They were told it was probably nothing. On her daughter's exact one-week birthday, while holding her newborn in her arms, she got the call: aggressive triple negative breast cancer.

In this episode of Wisdom Stripes, Meg Tuohy sits down with Parul Samani, MIT and Harvard Business School trained strategist, cancer survivor, mother of two, and author of The Path of Least Regret. What began in a NICU became a five-phase decision-making framework now used by Fortune 100 leaders and medical communities worldwide.

Together they explore how to make the hardest decisions without a guaranteed right answer, what it means to lead your family through uncertainty with honesty and courage, and how grounded hope... not blind optimism... is what actually gets you through. Parul also shares the story of advocating for her mother's genetic testing, the ovarian cancer they caught just in time, and what her husband said on the first day of chemotherapy that she will never forget.

This conversation covers: the Path of Least Regret framework, lifespan vs. healthspan, BRCA genetic testing, raising children with a family cancer history, processing grief without getting stuck in it, intergenerational resilience, and why chemotherapy ages the body but matures the mind.

Pick up Parul's book at parulsomani.com and follow her on Instagram at @PDSomani. Follow Meg at @MegTuoheyOfficial. New episodes of Wisdom Stripes every week.

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