Welcome to This Week in Emergency Medicine. This week we're covering 7 notable papers spanning critical care controversies, diagnostic dilemmas, and novel tools for the ED. Let's dive in. We begin in critical care, where a highly anticipated trial provides a definitive, and concerning, answer on a popular therapy for severe burns. Published in JAMA, the VICTORY randomized clinical trial investiga…

This week's papers:

High-Dose Intravenous Vitamin C and Mortality and Organ Dysfunction in Severe Burn Injury: The VICTORY Randomized Clinical Trial. — JAMA 2026
Temporal trends in treatment and outcomes of patients with cardiac arrest due to pulmonary embolism: a nationwide inpatient database study. — Resuscitation 2026
Estimating the Effect of Hospital Admission on Health Care Outcomes and Spending Among Persons With Dementia : A Quasi-experimental Study. — Annals of internal medicine 2026
Modified HEART score to improve ruling out acute coronary syndrome at the emergency department. — Internal and emergency medicine 2026
Racial, gender and language based disparities in sepsis: a public health perspective. — Internal and emergency medicine 2026
Guideline-Integrated Large Language Models Improve Decision Support for Acute Ear, Nose and Throat Emergencies. — The Journal of emergency medicine 2026
Bicarbonate Administration in Severe Hyponatremia (BASH): A Retrospective Cohort Study of 8.4% Sodium Bicarbonate in Patients with Preserved and Reduced Renal Clearance. — The Journal of emergency medicine 2026