Welcome to This Week in Pediatrics. This week we're covering 8 notable papers spanning surgical decision-making, care for our most vulnerable infants, and the future of molecular medicine. Let's dive in. [PAUSE] Our first theme covers clinical crossroads in surgery and screening, beginning with a major trial in The New England Journal of Medicine that addresses a long-standing question in pediatr…

This week's papers:

Human haematopoietic stem cells remember inflammatory stress. — Nature 2026
Decompression with or without Duraplasty for Chiari I and Syringomyelia. — The New England journal of medicine 2026
Coordinated regulation using small-molecule drugs enables controlled therapeutic genome editing and enhanced genomic precision in situ. — Science translational medicine 2026
Fibroblast growth factor receptor inhibition for succinate dehydrogenase-deficient gastrointestinal stromal tumors: a phase 2 trial. — Nature medicine 2026
Prevalence of Cerebral Abnormalities in Children With Congenital Heart Disease: A Systematic Review and Meta-Analysis. — Pediatrics 2026
Geospatial Indices of Neighborhood Environment and Preadolescent Behavioral Health Screening in Primary Care. — The Journal of pediatrics 2026
Extended Continuous Positive Airway Pressure in Infants Born Preterm Decreases Intermittent Hypoxemia: A Secondary Analysis of a Randomized Controlled Trial. — The Journal of pediatrics 2026
Urolithin A attenuates inflammation and enhances barrier integrity in an experimental NEC-in-a-Dish model. — Pediatric research 2026