← Biohacking Beauty: The Anti-Aging Skincare Podcast
Biohacking Beauty: The Anti-Aging Skincare Podcast
Exosomes 101: The Truth About Cellular Messaging in Skincare - Part 2
00:21:18
Loading summary
Transcript66 lines
- [00:00]
A
Foreign. Welcome to another episode of Biohacking Beauty. My name is Amitai Eshel.
- [00:13]
B
And I'm Anastasia Khoja.
- [00:15]
A
And we are the co founders of Young Goose Skincare, the world's first longevity biohacking skincare. And today we are basically continuing our deep dive into the world of exosomes. And that's because we've gotten so many questions since the episodes we launched. The first episode we launched about our vampire exosomes and basically, you know, our first exosome product. And it's so much more than that. Right?
- [00:49]
B
Yeah. Yeah. And there is a lot to unpack.
- [00:51]
A
Yeah.
- [00:52]
B
Because exosomes on the label doesn't mean much unless you know the dose and the composition and everything that you need to know, which we're going to be talking about. Now, some brands just sprinkle the word on a packaging, but never say how many exosomes are actually in the label. In the bottle. Sorry. Yeah, yeah.
- [01:13]
A
And that's a big, big problem. Without a verified count, you can't know if the C serum has a few million, a few billion, or none that are even active.
- [01:25]
B
Yes. And it's the difference between whispering to your skin once a week or having a full conversation every single day. So what I'm getting at is that it really does translate to efficiency and results. So you need to know exactly.
- [01:41]
A
In regenerative science, dose matters. The. The body responds to biological signals in proportion to their concentration. Too low and there's no message. Too high. If there is such a thing. And with too much stimulation or too much damage, you can overwhelm the system.
- [02:04]
B
Yes. And you know, with the biohacking crowd, there's always too much. So I think it's a good PSA still. And that's why we've built vampire exosomes around a quantified dose. So 3 trillion verified platelet derived exosomes in every 30 milliliter bottle.
- [02:23]
A
Yeah. If you're, if you're wondering what that means, it breaks down to about 100 billion exosomes per milliliter. Or roughly 50 billion per two pump or per application.
- [02:37]
B
Yes, every pump delivers a predictable, consistent signal. Same strength, same purity every time.
- [02:45]
A
And unlike most skincare, we don't just tell you it's verified. Each batch is tested independently for count purity and even the Microrna profile.
- [02:58]
B
And that profile is important. It's like reading the ingredient list of, of the message itself. So our sequencing shows about 43% of what's inside those axosomes is Microrna. The tiny regulators that tell cells how to make collagen, calm inflammation and renew the skin's structure. Now we are actually going to be having the test results shown on the website. So ever since the beginning of our company, we've always had full ingredient list on the website for every single product, which is not the case for many other skincare companies. And with the accessomes we went one step further that you're going to even have the exact third party test analysis of the exosomes. So it's really unseen transparency for the market.
- [03:56]
A
Yeah, and I think it's the major emphasis here is those micrornas. You can think of micrornas as the software update for your skin or for your cells guiding older cells to behave like younger ones.
- [04:13]
B
And again, transparency is really everything. That's why we've created a QR code for every batch. You can scan your own bottle and see the exact exosome count and the microrna fingerprint of your exact product.
- [04:30]
A
Yeah, and that's coming up. We're working on it. But it's important to understand that that level of proof doesn't exist anywhere else in skincare. Most brands still use vague phrases like exosome technology or you know, they give it like a fancy trademark name, but really without ever publishing real numbers. And the reason that is important is because there are even companies that are going to publish research around their exosomes. But because they have never tested what's inside the exosomes, the product you're getting is by numerous other donors. Could be even they've sourced them somewhere else. But even if they didn't, even if they sourced it from the same place, they can never guarantee that they are. You know, they hold within them the exact makeup that the exosomes that been that have been researched actually hold.
- [05:29]
B
Yes. And all of that really matters. If a serum only contains a few billion exosomes in the whole bottle, the skin might not even notice. And that's what we were talking about. Sometimes, you know, the exosomes are just kind of like purely used for branding. You really need a biologically active dose to create meaningful signaling. And actually recently we were at an in person event and what I loved is meeting some of our podcast listeners who were also attending that event and how knowledgeable you guys are. And I know everyone that's listening right now. You are listening to this podcast, shout.
- [06:09]
A
Out to vry, by the way, Vry in Atlanta.
- [06:12]
B
Yeah, correct. So what I was saying is that the people that are listening to this podcast right now really are want to understand what's inside their bottles, how it will interact with their biology. So you're doing your homework, and I'm very, very happy for you. And I wish that was the approach for everyone.
- [06:30]
A
Yeah. So I think when people ask online and we got, you know, thousands of those questions, you know, what makes this different? It's pretty simple. First, it's transparency, it's consistency, and it's potency that's backed by real lab data.
- [06:48]
B
In other words, it's not just marketing science, it's measurable science.
- [06:54]
A
Exactly. You should be able to verify what your product or what you're putting on your skin the same way you check the specs on a supplement or a performance lab test.
- [07:08]
B
And we really believe that's the future of high performance skincare. Proof of dose, which what will back up the promise?
- [07:17]
A
Yeah, we've talked a lot about exosomes as messengers, but here's something most people miss. Your skin needs the energy to act.
- [07:28]
B
On those messengers, and that's where NAD comes in. NAD is a Coenzyme foundation found in every cell.
- [07:36]
A
It's fond of a lot of cells.
- [07:39]
B
Cells are fond of nad, and it's found in every cell. And it's basically your skin's fuel for repair. Without it, even the best exosome signals can fall flat. Now, I do want to make a distinction here that we are not talking about NAD precursors. And I know we've gotten some of the comments and questions around that as well, because the exosomes are delicate ladies, and the NED precursors are sort of also, you know, need a specific, specific environment. So you want to tell them more about how we went about it.
- [08:17]
A
Yeah, I would like to maybe hammer home, like, why you would need both for regen, real, true regenerative results. Because think of exosomes, you know, first of all, they need to check all the boxes that we've been talking about until now. But think of exosomes as text messages, as we said in previous podcasts, and NAD as the battery on your phone. Right. You can have the clearest message in the world, but if your phone's dead, nothing happens.
- [08:49]
B
Exactly.
- [08:50]
A
Right.
- [08:50]
B
So NAD controls hundreds of cellular reactions. Most commonly known and most important really are DNA repair, collagen production, antioxidant defense, and even how quickly your skin recovers after stress.
- [09:06]
A
Yeah. And as we say, often the problem is NAD levels drop dramatically as we age. By the time you're 60, you have half of what you had when you were 30, but so maybe even by the time you hit 50s, but basically you have half or you have an insufficient amount of what you had when you were in your 20s and 30s. And the skin, since it's exposed to a lot more stress than the rest of your body, the difference is even more stark. There's just more demand than anywhere else in your body.
- [09:38]
B
Yes. And when NAD plus is low, cells can't respond efficiently to exosome cues. So remember, exosomes tells your skin cells what to do and how to repair. And, you know, there are. Exosomes are messengers relating a message. You still need your own resources to act on this message. So the signals arrive, but the skin doesn't have the energy to follow through.
- [10:06]
A
Yeah. And that's. Now, I'll get back to what. To what you said before. That's what we pair our platelet derived exosomes with what is called rejuvenate or rejuvenad, which is a proprietary sunflower sprout extract that is proven to activate N ampt. This is the enzyme your cells use to recycle or to kind of make their own nad.
- [10:33]
B
Exactly. So, so not NAD precursors, but something kind of even cooler, you know, because you still have, like, if you're a young user, you still have your NAD precursors in your moisturizer, for example, like you, Thiele and many of our other products. So really, when you think about this combination of rejuve NAD and the exosomes, it's like charging the battery while delivering the message. The exosomes tell the skin what to do, and the NAD gives it the power to do it.
- [11:07]
A
Yeah. Studies show that when NAD levels are restored, cells produce more collagen, repair UV damage faster, and clear out zombies or senescent cells more effectively. And remember, we said that this is also a kind of unique feature of platelet derived exosomes that, you know, one study showed that it can clear up to 40% of the zombie senescent cells in that area when applied topically.
- [11:37]
B
Yeah.
- [11:41]
A
I want to take a moment to tell you about something we've been working on for years here at Yungoos. Our newest innovation, vampire exosomes. You've probably heard us talk before about how most skincare focuses on surface fixes. A cream here, a peel there, while ignoring what's actually happening inside your cells. Vampire exosomes are different. They are PRP derived exosomes, meaning they come directly from platelets, the body's natural repair system. Each exosome carries micrornas and growth factors that tell your skin to repair, renew, and reorganize collagen. Basically, it's how your cells communicate healing directly to your tissues. What makes this launch so special is that we finally have quantified potency. Each 30 milliliter bottle contains 3 trillion exosomes, or 25 billion exosomes per drop. And every batch is third party tested for both exosome count and microrna profile. That's true transparency. You know exactly what you're getting and that it's active, stable and real. The formula is shelf stable, gentle, and designed to protect the exosomes. We've even paired it with Rejuve nad, a cosmetic active that boosts the skin's NAD economy. The molecule your cells are use for energy so the exosomes can actually do their job once they've been delivered. The results have been incredible. Early human imaging shows visible improvements in tone, redness and fine lines within weeks. Not because we're forcing change, but because we're giving your skin the right signals for repair itself. If you want to experience it, go to younggoose.com and use the code podcast10 for 10% off your first order. That's younggoose.com code podcast10. The link and the details are also in the show notes. And now let's get back to the episode.
- [14:15]
B
Like anecdotally, I want to share something with you guys. So Amitai's skin is very, has melasma on his cheeks and it's a very stubborn one. And we've talked before about some of our podcasts that a lot of the times melasma is like, it's really clusters of, you know, melanocytes that have senescence in them and that's how it manifests and shows in the skin. So when Amitay started using vampire exosomes morning and night, it really is mind blowing that his melasma lightened. I don't know if you can see it on the screen if you're watching right now, but really. And we, we didn't talk about it while we were just doing our skincare and we, we start to feel like we read each other's mind. And I was thinking that and he was thinking that and then we just said it out loud together that like it's, it's really pretty crazy how much his skin like the melasma got lightened. So I mean, that's really, really crazy.
- [15:18]
A
Yeah. So I have a question. So how would you. First of all, this is true, but kind of tying in NAD and exosomes, how would you describe the relationship between NAD and exosomes?
- [15:30]
B
Yeah, I think higher NAD doesn't just enhance exosomes results, it multiplies them. The two together create a loop of energy and regeneration that keeps producing, building over time.
- [15:42]
A
That's the, I think, the real definition of biohacking your skin, combining the messenger and the fuel so your biology can do the rest.
- [15:51]
B
Yeah, well put. When communication and energy meet, rejuvenation becomes effortless and sustainable. And really the, the consistent results is what we are all after.
- [16:02]
A
Yeah. So here's the bottom line. Exosomes are messengers. NAD is the fuel. By the way, interchangeably, when I say nad, nad, same thing. And together they let your skin perform the way it was designed to do. To perform.
- [16:20]
B
Yes. And that's really about activating your skin's intelligence. As we were talking about it earlier, your skin already knows how to repair and stay youthful. We're just giving it the right language and the plan and the instruction and then just follows it.
- [16:37]
A
And that's exactly why we created vampire exosomes. 3 trillion verified platelet derived messengers in every bottle, powered by the power of NAD to boost your skin's resilience, regeneration, and obviously appearance.
- [16:56]
B
Yeah, and I really never go out of my way to be like, hey guys, this is the best, like I love every single young goose product for me is a baby. And like you can't pick a favorite baby, I think.
- [17:07]
A
But that's our favorite baby.
- [17:10]
B
But this baby need to try.
- [17:11]
A
It's really good baby.
- [17:12]
B
Yes. So try it for yourself.
- [17:15]
A
Apply this baby on your skin and.
- [17:17]
B
See what happens when your biology finally just works with you.
- [17:22]
A
Finally gets it. Your biology finally gets the message.
- [17:26]
B
Yes, Yes.
- [17:27]
A
I think this is really the kind of the future of skincare. It's like it's smarter, it's not harsher, which was kind of the paradigm maybe 10, 20 years ago. Let's try to make it more harsh. No, it's just smarter. Okay, so what should they do if they like what we said?
- [17:45]
B
Okay, well visit young.com to experience vampire exosomes and start your own longevity skincare routine today.
- [17:53]
A
Nice. Okay. Yeah, that was kind of the end of that episode. Of course we can do more episodes about exosomes if, if there are more questions around that, mainly when, when, how protocols, things like that. For now, I think it's great.
- [18:07]
B
I also will say that we have like 18 questions on the PDP of like the product page of Empire Accessomets on the website, and these are real frequently asked questions. So we tried to address most of it in the last couple of podcast episodes, but if we missed something, it's probably there. You probably can find that amen question answered there.
- [18:31]
A
Before we wrap up, it's really important to understand that if you like the information that we've shared with you, if you think it's unique, if you think other people should hear it, the only way for us to reach more people and educate more people is if you like, share, subscribe and leave a review, which is what we're asking you to do now. And before we leave, we've instituted something of a staple which is we're going to read one review and that person is going to get our a full size of our Blue Peptide spray, another one of our favorite babies. So do you want to read a review?
- [19:11]
B
Yeah, I've actually I just read this one for the first time when you were introducing that I'm about to read the review. So if you were watching and you were like, what's with her face? It's a cute review. I honestly sometimes choose them at random so everyone has a chance to win. So this week's winner. The subject line goes, you won me over. And the text goes. I'm an esthetician at a well known spam. I always start my facials by going over their current skincare regimen. A client told me they were using yangoos. I about lost my marbles. I've never talked to someone personally who uses the line. The next hour was spent with her telling me all about the products and how much she loves them. She struggles with rosacea and her skin looked amazing. She made a believer out of me. I can't wait to try the products myself now. So you like a lady will try the product. We'll send you the Blue Peptide Spray. Thank you for leaving the review.
- [20:11]
A
And what's her name?
- [20:13]
B
Yes, exactly. I'm getting there. So the name is Tahoe T A h o e 1984. So again, thank you so much for leaving this review. I I love to to hear those stories and and guys, if you love the podcast, if you love the products, leave a review and maybe yours will be the review I'll be reading next time.
- [20:39]
A
Amen Again. If you really like what we're doing, if you want to try the product products, if you want to try Vampire Exosomes or any other product, go to young.com use the promo code podcast10 to get 10% off your first order and we'll see you here next time.
- [20:55]
B
Bye. Thank you.