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Welcome to the Biohacking Beauty Podcast, where we explore skin aging through the lens of cellular science and regenerative biology. I am Anastasia Hojaeva.
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I am Amitai Eshel.
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We are the founders of Yangus Skincare.
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And the hosts of Biohacking Beauty Podcast, the podcast that makes sense of longevity science and applies it to your. Your pursuit in looking your best. Correct.
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And today we are joined by Jess Kane, co owner and chief marketing officer of BodyBiome, to unpack the connection between visible skin aging, advanced skin care, and internal cellular health.
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In this episode, we dive into why even the most cutting edge skincare and red light therapy fall short without the right cellular building blocks.
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We talk about how cellular membrane health directly shapes the way we age, why omega fats are so widely misunderstood, and why most liposomal supplements never actually make it into the cell.
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If you've ever wondered why advanced skincare treatments aren't the delivering the results you expected, and you know, what can you do internally to support real, lasting change, this conversation is for you. Welcome to the Biohacking Beauty Podcast.
C
Thank you for having me.
B
Actually, I want to start. It's a little bit off the this, but did you hear that Dr. Paracone, which is like, old school. Old school, but good school. I mean, respect. Dr. Perkin, huge, like, conventional kind of Sephora skincare brand.
C
Yeah.
B
He's going to write a book about phosphatidylcholine.
A
Really?
B
And that it is a longevity molecule. Yeah. I don't know when it's going to be out.
C
Stop.
B
He told us that in confidence. He said, don't tell anyone. No, I'm kidding.
C
He said, I got to reach out to him.
B
Yeah, yeah, yeah.
C
Interesting. I mean, it is. I think it's the best longevity molecule. I just think that it's not sexy. Right. It's biology. It's like basic biochemistry.
B
That's it.
C
It's what?
A
It's too pissy to be sexy.
C
Exactly. Yeah.
A
Well, I think on that note, we can kind of talk a little bit about the fact that right now, a modern woman, you know, it seems like she's doing everything. You know, she's doing her regular facial, she got her red light therapy in her skincare, and yet, you know, she still battles, like, all of the signs of aging, you know, everyone does. Right. Like, she's still concerned about her skin being dry and having the lines and you coming from a different perspective. And, like, what is. Do you think? Is she missing anything from within? Is. Could it be that, you know, she's only doing the superficial approach. And it can only get you so far.
C
But I think so.
A
That's not the answer.
C
I really think so. And I think in today's world we're trying to do everything. I mean, for me personally, I try to do everything as natural as possible with active. Like, I'm not a crazy. I don't have to look at it from the perspective of like every single ingredient needs to be something natural. I'm not putting beef towel on my face.
A
Oh, good.
C
But I am not.
A
We can be friends.
C
Yeah, exactly right. I don't want, I'm not doing, you know, a ton of injectables and things like that. And I'm looking for the most natural approaches to aging. I want to age and look good. I don't want to look crazy. I just want to look healthy. And I think in today's world we're doing all of these things, but we're not thinking enough about the actual building blocks of our skin and the scaffolding and what holds it together. And I think that we need to just start thinking about that more because I think that the low fat era of the 1980s is so pervasive and has stuck around for so long that we are eating less fat than ever. Well, probably not as much as little as we were in like the 1990s and the 2000s, but we still think that fat is olive oil and avocados. And that's not the, that's not what makes up our skin.
B
I think more than that. I mean, first of all, you're correct. And as human beings, as we say quite often here, human beings are really not well built to measure incremental change or to feel or to intuit incremental, incremental change. If it was so as, as I often say, McDonald's would have been out of business.
C
Yeah.
B
But it is also true to say that our body within seven years is almost, is rebuilt anew every seven years. You know, depends on the, on the cell. But we're basically, whatever we're putting, putting in is going to be part of the makeup of our cells, etc as time goes on. So the, although we're used to thinking of, I'm going to wait until I'm, you know, fill in the blank to get plastic surgery. I'm going once every three months to do this laser, I'm going to do once a month this and that. The reality is, is that those micro decisions of, you know, what am I, what am I supplementing on, whether it is with food or with supplements or whatever that is, on a regular basis, these small inputs are the ones that are going to quite literally be our body within. You know, whether it's skin cells, going to be a month, you know, your mitochondria, it's going to be like, you know, two weeks, et cetera, et cetera. Yeah, yeah.
C
And that's reflective in our skin. Our skin is our largest organ. So if you're taking care of your body from within, you're taking care of each of those cells. Those cells make up those various different organs. And your skin is your largest organ.
A
Yeah, well, you often say that. Well, just I hear you say that the cell membranes is the foundation of skin health. And can you, like, expand on that? Can you, you know, address how it affects the skin barrier?
C
Yeah, it's really fascinating. So phospholipids are. And phosphatidylcholine is what makes up the bubble that protects each of our cells. There's in women, 32 trillion cells. In men, they estimate it's about 40 trillion cells. Each of these cells has a barrier that protects the cell, the world, oxidative stress, toxins, all of these things break down that cell barrier and that cell bubble that's protecting the cell. So you're constantly making phospholipids, and you're constantly losing phospholipids. I think we're probably losing them at a higher rate in today's world. We also tend to lose them as we get older. You have less ability to actually synthesize them from foods. So what's really interesting about the skin and the outer layer of the skin is phospholipids essentially act as, like the cement between bricks. It's what holds everything together. And when you don't have enough of it, you're going to see it in your skin quality, in your sk. In texture, in skin laxity. And so it's just really critical. These bioactive lipids like phosphatylcholine, omega 3, omega 6, these essential fatty acids for the fluidity and the balance in. In our skin.
A
Yeah. And actually, first of all, I want to say that I'm obsessed with your opc. Like, I'm obsessed. I have, like, a year worth of stock because I never want to run out.
B
There is someone that's even significantly more obsessed than you? Yes, actually, significantly. I'm talking about, like, every baby.
C
Yeah.
A
Every since I chatted with you and you said that we can give it to our baby, like, you know, one year old, and we started giving to him at 20 years old and he loves it.
C
My kids do.
A
He actually is calling it yum Yum.
B
Yeah, that is called Yum yum.
A
And he's asking for more. Like every time we give him like a half of a teaspoon, he's actually asking for more.
C
I literally pour it directly in my kids mouth. They're like little birds, they just, I said it's brain Betty time and they all just go. And my youngest always asks for more and I think that they need, they know what they need. Of course they're also going to ask for shower.
B
If they know what they need then he really needs watermelon.
A
Like cute. Yeah. But it's so amazing to me and yeah, I've been recommending it to my mom friends and I don't want to brag. It's really hard not to brag. But our kids already at this age speaks in three languages and sometimes we're at points parties and people are like what's your secret? I'm like, we don't really have a secret but, but we do give them just the one supplement and you know, this is what it is. So I already have a couple of mom friends. I love it on it as well.
B
Yeah.
A
But yeah, so I'm personal obsessed and I can see it on my skin sometimes if I travel I don't take it with me and anyway travel tends to dehydrate our skin and you don't look your best after traveling. But I can actually test that when I take the PC. I like, I, my skin looks plumpier and juicier and so I, I've said it on this podcast before. I've like shared it on, on Instagram. Like it's my non negotiable. But you mentioned something about Omega 6s and Omega 3s and I feel like there is so much misinformation and people are just like they're only talking about omega 3s and they sometimes don't understand that there should be a specific ratio between the two.
C
Yeah.
A
So. So can you educate us a little bit on that?
C
People assume that all of us are eating too many oxidized omega 6s and that's the whole seed oil debate. But the reality is our cells, our cell membrane needs a ratio of 4 part 6 to 1 part 3. So slamming fish oil is not the answer because that's the one part that's the Omega 3 and you don't need that much fish oil. Eating fresh fish is a great way to get fish. Caviar is actually the best way to get whole, really good quality fish. So that's what we're doing.
B
That's already in phospholipid form.
C
Exactly. But the 6 debate is really interesting because a lot of people say, well, we eat too much processed foods. But if you are someone who is already health conscious and you are not eating processed foods every day, you're not eating McDonald's or chick fil A and you're not frying everything in canola oil in your home, you need unoxidized sixes. And they provide that bounce and that fluidity. The bounce that we get to our skin is part of the essential fatty acid matrix that works in conjunction with phospholipids in that. In the bilipid layer. So there's cholesterol in there and there's proteins and there's the electron transport chains. There's all sorts of wonderful little things that happen on the cell membrane, but the majority of it is made up of essential fatty acids and phospholipids.
A
And that's sort of the approach you took with the balancing oil, right?
C
Exactly.
A
Is that the one? The four to one ratio?
C
Right, exactly. And this is from research, actually. Interestingly enough, it was many Israeli researchers in the 1980s who determine that that was the ratio in the cell membrane. And so it has always been an organic cold press, very carefully treated. We recommend people refrigerate it. But the one thing I constantly hear, because I'll often tell my friends, they'll say, I want to get started on body bio. What should I take? Start with foundational PC balance oil butyrate. And within one month, they're writing to me going, why does my skin look so good? Why do I feel more, like, refreshed?
B
So I want to, you know, kind of go back to PC, which is the bottle's gonna say PC, because phosphatidylcholine is allowed to write on a bottle. So.
C
Yes.
B
Which tastes like walnuts. I don't know why. Why is it difficult? And this is a kind of an within the zeitgeist of, like, health conscious people, especially people who have been health conscious for, I would say, over like 15 years. It is like a kind of a. The same way, like you talk about the weather, you're going to talk about the difficulty of getting good phosphatidylcholine. So why is it difficult to source good phosphatidylcholine? And where would you know from your experience? Where would companies go wrong sourcing phosphatidylcholine?
C
It's an odd thing that was allowed in the history of soy production. And there's a great book called the History of American Lecithin my grandfather had on his shelf. And essentially they used a byproduct of soy production that produced about 20% phosphatidylcholine. And it's combined with essentially vegetable oil. So it's called triple lecithin. It's essentially lecithin is the byproduct. It's then packed with some oil, and that will, when you test it in a lab, it will show that it will yield about 30% phosphatidylcholine. The problem is that's not liposomal. And so most of the phosphatidylcholine on the market is just that product. When you go to a contract manufacturer and you say, hey, I just want some phosphatidylcholine, that's what they're going to provide you. It's essentially lecithin in oil. It's actually called technically, triple lecithin packed in oil. And what happens when you consume that is it breaks down into triglycerides and choline. It's not going to provide the building blocks of the cell membrane. Choline's great. Triglycerides, not so much. But it's not going to get through the digestive tract into the bloodstream for.
B
Cellular delivery, Especially not for the brain, right?
C
No, it's not going to cross the blood brain barrier at all. So what my grandfather did in about 2002 is they were using IVPC in the 1990s when they first started Body Bio, and they were doing it based on blood testing that they were doing and doctors working with extremely challenging neurological issues and chronic illness cases. And he started to develop. It took about four years. One of the gentlemen who he made PC with originally, still at our company, he's one of the longest employees that's been there.
B
Wow.
C
And he's currently making butyrate. And they just tinkered around for years, just playing with how do we create a process that's going to yield a liposomal phosphatidylcholine, which is exactly what our product is. So the difference really, with us versus other products on the market is we know ours is truly liposomal. We've done extensive, extensive testing to prove that we actually can see how it's taken up into the cells. We did a massive study this year at the University of Connecticut with a mitochondrial research lab just to see how the liposome. So it's not about liposome size, it's not about any of these things. It's about how it's actually absorbed in the body. And that was really exciting to see this here.
A
So for our listeners, if maybe they want to look at the labels of their supplements, if it's not body, you won't know. Right. That's the thing that sucks just the.
C
Same with Liposom supplements.
B
Wow.
C
If you look at a liposomal supplement, you're standing in Erewhon or wherever that has a bunch of them and you look at 10 different companies, I would probably tell you nine out of 10 are not liposomal. Yeah, they just put that triple lecithin ingredient in with glutathione, with vitamin C, with whatever and you can call it liposomal. According to the fda, there's no regulation, there's nobody to test it to say this is, you know, this is actually effective.
B
It's what I say a lot about. So it's very, extremely difficult to explain sourcing to anyone who is not by the way, to anyone who's even cosmetic chemists, like even people who are dermatologists. If you're one step removed from touching the raw material, you might as well be the end consumer as far as like your level of understanding. And a lot of the times my way to hammer it in is saying, do you know how there is a difference between your local butcher, his grass fed beef and sorry, McDonald's. I am so sorry McDonald's, but like meat at McDonald's.
C
Yep.
B
That, that, that obviously is not great. That's less of a discrepancy than between two identical ingredients that you can source for.
C
Agreed.
B
By the way. And you source, normally you source like raw ingredients. You would source them and we would source them almost from the same, you know, starting point manufacturers. Obviously they're going to do.
C
Yeah.
B
So it's very difficult to know. And I think if someone wanted to choose like their partner, like their supplement partner in their life, the people who they kind of get supplements from, it's not like you should like you should like the owner of the company, but you should understand how they make decisions and you should trust their decision making because you won't be able to understand where they're, they're sourcing their Omega 3s and how, you know, what is their decision making. I mean my heart was broken recently where I realized that the Omega 3s that I was taking for, you know, until like two years ago, but for a very long time decision making was horrible there.
A
And, and actually like all of the guests that we bring to this podcast, are they all vetted by us? And this podcast episode is not sponsored and none that word here sponsored by.
B
Young goose who is us.
A
Yes, but it's true. We take it very seriously that people trust our opinion and we get questions all the time from our listeners. Recommend us red light therapy device supplement stack everything, things for everything, hair and yada, yada, yada. And we only bring guests that we, we know, like they're founders of the companies, but we know that we can trust them, like they will make good decisions like Amitay said.
C
And I think it's the same for skincare. It's the same. It's anything you're putting on your body, it's in your body. And it's hard to make those decisions these days. Right? Well, because so many companies have, you know, maybe sold and those, those decisions then are altered when a company sells.
B
So I'm not going to talk about the, the company, but there is, we have a company that, I mean the owners used to be, they're still our friends and we've, we were very vicariously involved in the trajectory. What happened that a company, after it got sold and it got sold to one of the biggest pharma companies in the world, a subsidiary of one of the biggest pharma companies in the world, we have many, many, many friends who are still employees of that company. And the only reason the company got bought out is because the parent company had ingredients where they basically was looking for a home for those ingredients. And they literally did like we call it in Hebrew, Red Riding Hood. I don't have no idea why, but they're, they switched out the core actives of the same. The formula is called the same. It looks the same, but it's not the same.
C
Well, I think our missions are different than those companies. That's a large conglomerate that's looking at shareholder value. We don't have to do that. And I think it's tough, right? You look at companies that have raised capital and are expanding massively and what they're going to do. And I spent so much time listening to these podcasts about these companies just scaling so quickly when they, when they bring on equity and you're like, God, that's gotta be great. I mean, yes, stressful, but cool. I mean, an incredible experience. But they're also looking at the bottom.
B
Line if it has to, like, that's how you scale massively. You cannot get a certain amount of money. Aim to do 10x but not cut costs. I think Most people don't understand that there are two vectors of a company raising in value.
C
Yeah.
B
One of them is definitely increasing the bottom line, but exactly in a opposite and equal force is the force of reducing cost and redundancy.
C
And that's going to look at. They're going to look at every single raw material. So if I put the best vitamin C out there, they might go in and say, we can get that cheaper and you can cut costs on this. That's the difference you're saying.
A
Exactly. Word for word. Where we talked about on the bonus episode that we released about companies being bought out, we talked about road getting acquired and some other companies and why we at Yungu don't have investors and we are not raising money for this exact reason. Like, it's the same exact situation. Like, every ingredient that we use, we source. It's like pharmaceutical grade and it's just the purest form and it's expensive. And that results in a certain price point of our product. Exactly. But yeah, we've already had people that gave us advice, you know, financial advice, where like, exactly. Like you can have it have cheaper and you can bring prices down more people can experience your products, but it's not going to be the same product. It's not going to do the same. It's not going to like, it's not going to be Yungoos anymore.
C
Exactly. And so that's what people often say. Well, Your, you know, PC is $200 a bottle.
B
Yeah.
C
It's meticulously made. There's 10 people that go through the process of just manufacturing it.
B
It's also a gigantic bottle.
C
So it's the most ridiculous bottle. There's some aspects of the company that have just been kind of grandfathered down, literally from my grandfather that like, of course I wish I could change the name. Right. There's too much brand equity in the name now. But, you know, if I was starting from scratch, I would do a lot of things very differently.
B
You know, the. The starkest example I have for the same ingredient is ergothioneine. Ergothione. There are two companies that are the leaders of supplying it for skincare because it needs to be kind of dialed in for skincare. One of them is in China. One of them is in France. The Chinese version costs $300. The French. French version costs 5,000. Exactly. So, I mean. Yeah, you know.
C
Yeah.
A
Actually in our intro, we would have already introduced you and everything, but you mentioned your grandfather quite a bit. Yeah. And I just. I think the way I see you you know, you one of, like, inspirations to me. You're like, you're this girl boss. You know, you're. You're a mom, mompreneur. And you're running this company with so much grace and with, you know, and I am curious to hear and for the listeners to hear maybe how the company started and. And then what did you do differently when, you know, you took it.
C
Yeah. Day and night. Yeah, the company was started.
B
Well, if you, if you switched them from working at night to working during the day, that would not be huge.
C
Everybody works overnight. No, he. They started, he started. He was an entrepreneur. He had heavy metal toxicity. He owned a steel factory. So my band, my family was in the steel industry for time in the 1980s. He, like, could. Had to stop running marathons, was getting really sick. He. He was. He refused to take that diagnosis. This, you know, there's nothing you can do about it. And he went to the ends of America. I mean, I think he was in Oregon and Washington state and in California because there was no Health and Wellness in New Jersey. It was a very small group of people kind of starting the integrative and functional health movement. And a lot of the, the peers in that space are still around doing different things. But this is at the same time that Thorne was starting and Metagenix and Zymogen and all these companies and, you know, way before the days of like an IFM type of thing. So he started. They started initially doing blood tests. Used to be able to walk into a lab core and get a Body Bio blood test. Same exact thing as Function Health is today. Used to be able to do that at Body Bio and it was $100 a month.
B
Wow.
A
Mind blowing.
C
And you could just walk in and get it. But they found that there were certain things that they were seeing consistently at the same time. They were doing all this research and putting together with doctors, a group of, kind of a consortium of doctors, this IV detoxification protocol. And he looked at it and he said, look, everybody needs this. This. The need is getting greater and greater because of this. This world that we live in, but it's inaccessible. It's drugs. A doctor needs to prescribe them and then it needs to be done via iv. So it's a very, very complex grouping of drugs for detoxification. So he went on a. A journey just to start to figure out how to make them into pill form and into liquid pills, whatever they were, but in a supplement form. And so he developed those. And they were all pretty much developed by about 2006 took a long time and now we have three different manufacturing facilities where we manufacture the different products. And the thing that they were doing really differently is they only sold to doctors. And so they would lecture about 50 doctors a year. They would host this small conference in New Jersey. They would have incredible. I mean, the leading voices in functional medicine, even Mark Hyman has been. And they would lecture these small groups of people and then those doctors would take it to their practice and they would practice this detoxification protocol. And every single patient that walked into their office, they were putting on PC, they were putting on balance oil, they were putting on butyrate, they were using glutathione. It was the exact same thing as the detox protocol, an IV form into a nutraceutical. And so when we came along, my husband, he recruited my husband. After we got married, my husband really helped build Fiji water in Europe, Middle east and Africa. And we were living in London. And he said, I need help. I want to do something with this business.
B
I think if you can sell water, you can.
C
Exactly. You can sell plastic, bottled water. And he said, we have, Everybody else has the sizzle, we have the steak, and I just don't know what to do with it. And he thought you needed to turn it into a drug. He was convinced that we had to go down the IND turn it into a drug route. And my husband came to, got involved. I was heavily pregnant with our first baby and we kind of sat with him and we said, pop up. You don't have to do it this way. You can. People are really taking their health into their own hands. We just have to really lead with education and, and lean in on the practitioners that already trust us to be those voices to help amplify and get the voice out there. It took years, though.
B
Yeah, yeah, it took years. But this is really the golden age of. I mean, we're still in it, but the golden age of what we call consumer facing medical. Yeah, technology strategies, whatever that is, where I mean, many things aligned. Some of them are financial hardships, like, you know, the 2008 crisis. Some of them are things like Covid more recently. Yeah, but there were things that basically detached people from that central nervous system, central backbone of, of stringent medicine, where you have to go to one person, it. There's many bottlenecks for you to get 100% and people wanted to take again, micro solutions home to which if they can just adhere to the protocol, they can get results at home. So.
C
Exactly.
B
It's. I mean, it's a beautiful example of this happening.
C
Yeah, yeah.
B
Let's take a second to talk about skincare during winter. Here's the part most people miss. Winter does not just dry your skin. It changes how your skin produces energy and repair itself.
A
When temperatures drop, transepidermal water loss spikes, mitochondrial output slows and the barrier starts losing ground faster than it can recover.
B
This is why skin becomes reactive, inflamed and unpredictable in winter. Even if your routine worked perfectly all.
A
Year, most people respond by adding a heavier moisturizer. That does not address the problem. So we built a system instead.
B
The Winter Skin protocol is how we protect the skin when repair capacity is compromised by cold, wind and low humidity.
A
It is not a generic routine. It is tiered by metabolomic skin agents with clear guidance on when the priority should be protection versus repair and how to adjust when travel treatments or environmental stress push the skin past its threshold.
B
Inside the protocol, you will find structured morning and evening routines, red and near infrared light timing and targeted strategies for the areas that break down first in winter, including the neck, chest and hands.
A
If your skin becomes tight, red or reactive every winter, this removes the guesswork.
B
If you want to go deeper, you can download the protocol and see the full system. The link is in the episode description. Your skin already knows winter is different.
A
Your routine should reflect that.
B
So we're talking a lot about like kind of cell health forward type metrics, whether it is balance oil, whether it is PC, which both of them are heroes in our house. But you also again talk a lot about butyrate. Yeah, and butyrate is different because. Well, I'll let you talk about it. But it is a different approach than. Hey, hey, body. Here's that end molecule you're going to use. You're going to employ in different in every cellular process. So I'll let you continue. How is butyrate different as far as like a modality than giving the, the end building block of, of a process?
C
Yeah, it's, it was part of the original IV detox protocol. So the, the detox protocol was phosphatidylcholine, it was sodium phenylbutyrate. And I'll explain the role in the detox. Glutathione, leucovorin, which has become very popular amongst autism communities. Vitamin B's. That was pretty much the detoxification protocol. The role that butyrate has that's really fascinating is twofold from a detoxification perspective. It goes into the cell and it breaks down the bad stuff that's broken through the cell membrane and gone into your cell and embedded itself in your DNA. And it's changing our health trajectories. There's a reason that we have autism, there's a reason that we have neurological disorders. There's a reason children are getting colon cancer in their 20s. These things are not. They were not happening 50 years ago, they were not happening 100 years ago. So butyrate goes in and it shakes off that junk PC imbalance, oil. Go in to remove it from the body. That was the detox theory. From the functional perspective, butyrate's a fascinating molecule because none of us are eating enough fiber or resistant starch in today's world. And butyrate is a postbiotic. It's the end product of a perfectly balanced microbiome. You have the perfectly balanced food that you're feeding the microbiome, you have the right keystone strains of bacteria, and then sometimes they're going to produce butyrate. It's a highly inflammatory molecule. Anti inflammatory. It is.
A
I was like, maybe it's like highly inflammatory, you know, healthy inflammation.
C
No, that's omega 6. But it's, it's a really, really important molecule, not only for the gut, but for cellular function and detoxification. So it's part of that whole gut brain axis, gut cell, skin. I mean, so much is housed in the gut.
B
I mean, quite frankly, it started the bubble, no pun intended, but started the bubble around postbiotics and the hope that they're going to kind of be the.
C
Oh, yeah, I'm claiming that one for sure. Oh, yeah. Because when I sat down with my grandfather, I would sit, I would say, pop up, what is butyrate?
B
Yeah.
C
Four hours later, I didn't have an answer. And this is way before the time of ChatGPT, where you could take the whole recording, put it in there and ask it some questions. So we really had to distill, like, what is it? And how do we talk about it? And at the end of the day, they kept calling it a short chain fatty acid. But short chain fatty acids are postbiotics. That's what it is. There's several different postbiotics, not many, but it is the keystone postbiotic that is most important for our immune function, our cellular function, our detoxification function, our gut health.
B
Yeah, that's. I think taking it back to, I mean, anesthesia is the reason we do it. But one of the main modalities that we use for, for mitochondrial function is incorporating postbiotics in products that allow better utilization of oxygen or simulate you know, mitochondrial function for that matter.
C
Yeah.
B
And that's why I came up with a term hyperbaric oxygen.
C
Oh, I love that.
B
Yeah, that's so that basically I put.
C
It on before this. Yeah, I put it on.
A
You look glowy. You look glowy.
B
So there, there is, there is a. And to be frank, like we don't own. There's. There is no patent to be owned there, there's. You could do whatever you want with different back. Bit different like yeast etc to bypass patents that are. That do exist. And it's just that I think other companies are just like not noticing that there is like something that can wonderful modality that could be used for skin health.
C
Yeah, yeah.
A
I have a question about vitamin C. Like I know that vitamin C for a while. It's like, you know, it's one of the OGs. You know, everyone stuck. A lot of people think about it just from immunity perspective. But for like an advanced user who is taking vitamin C specifically for skin improvement, sometimes they take vitamin C and they don't see improvement in collagen. What is happening if it's not like if vitamin C is not absorbed effectively.
C
Same as glutathione actually. So glutathione and vitamin C are not well absorbed in the body and so you really want them in a liposomal form and not to like sit here and plug my products. But I wouldn't take a goo or trust other products. There's, there's actually a great. I do love live on labs out of Las Vegas. I love the og you know, they make liposomal products, but the amount of.
B
People who put them in shakes, blend them and d like break, break the liposomes is like I think probably 99 people out of a hundred.
C
Yeah, you're not. Yeah, yeah. I mean you have to be careful about how you take these things. But they're not well absorbed in the body and so you do want them in that form to really get into the cells and to stimulate collagen production. I think when you don't take. Look, I think all of these things when you don't take enough of these building blocks for our skin, you will see effects in your skin if you're not taking it from within because we're not getting enough from our food. We should, but we're not anymore.
A
Yeah, yeah, so I hear you.
B
But you do raise an interesting point. What would you tell someone who would come to you and I bet you actually hear that a lot and say, I heard glutathione isn't absorbed orally, it's a waste of time. I don't even understand why you're selling this product or however people phrase themselves when they talk to you. But that is something that we hear quite often. We specifically heard it when I had an immune protocol that I was doing and your products were part of that immune protocol. So I've heard it personally. So what would you tell someone who says glutathione? Just why bother?
C
I mean, most isn't well absorbed in the body. If you're buying it off Amazon, it's probably not. It needs to be in a liposomal form. It really does, in a truly liposomal form. So look out for things on labels. It will prob. Companies are getting smarter. So now they're putting, you know, derived from phospholipids, derived from phosphatylcholine. I would go so far as to call the company and say, hey, do you have any studies proving efficacy of your liposomes? This is stuff you're putting in your body. Take it seriously. Don't just pick it up at the supermarket. And I think when you really do take it seriously, you notice the gains. This is not something you're going to notice right away. You start taking vitamin C in two weeks, you're not going to see perfect collagen production and your face is going to look plump. But when you invest in the right products, just like you do for topical skincare and you invest in what you're putting in your body, you will see, I think after about a month, you see definite large gains.
A
Yeah, that's very encouraging, I think. What do you think of the beauty supplement trend? There are like so many companies that they're like doing skincare, but then they're, they're launching their beauty supplement. And how do you compare that to like cellular nutrition.
C
You know, apples and oranges? It's totally different. I think most when it comes to manufacturing, you can walk up to a contract manufacturer and you can say, hey, what do you have for skin? And they'll probably have a couple different blends that they've based off of Nutrafol or something else. Shout out to Nufol and you just kind of select, tick off that box, provide them with a label. This is the type of container I want it to be in. They do all the quality control, they do all the sourcing. You can't swap out ingredients, you can't make changes. You don't know what those raw materials are. You just have that finished product. And so I think these blends are fine. I like that companies like Nutrafol are really doing, like, clinical studies behind their product to prove efficacy. But I think for the most part, when they pivot into supplements, I always just think, like, stay true to what. What your name is. Stay true to what you are. Stay true to what the brand is really known for. Just like, I wouldn't go making a phosphatidylcholine skin cream. Although I think it's a great idea. I'd love for you guys to do it.
B
Yeah, it's a good idea. Yeah.
C
No, a little collabor.
B
Yeah.
A
Yeah. We definitely always get encouraged by our community to be like, please launch your red light therapy and launch microneedling pen and launch makeup and launch shampoo and conditioner. And we're always like, you know, I'm not gonna say no ever, ever, ever. But it's no for now because right now we're like, like you say, we're focusing on what we're really great at and where we have the expertise and we can deliver just the best experience of the best, you know?
C
Yeah. Yeah, exactly.
A
And it's also fun to collaborate with friends and uplift each other. You know, you do this and you get at this. I'm great at that and she's great at that. And let's race together instead of becoming competitors.
C
Agree.
B
So let's talk first of all. Yeah. That's why, you see, why she is the. She's the one that makes it work.
A
What's her title, first of all?
B
Just put the word co and then everything.
C
Yeah.
B
But let's talk about, you know, you have, you have the funny thing to say, but like, any, any, any like, online type, like concierge medicine right now are going to tell you 200 years of, of, of collective experience. Right. And it's basically. But you really do have. You house 30 years of product experience.
C
Yeah.
B
Which is rare.
A
Yeah.
B
So from the vantage point of skin health, what have you seen work? How does a protocol look like? And I would even ask you to say, how does a basic protocol look like?
C
Yeah.
B
And then how can people try and push the envelope and see if it works for them?
C
Yeah, I think so. I made it really easy this year because I had so many girlfriends who reached out to me to say my skin looks great, that I was driving one day and my best thoughts come when I'm driving by myself and I don't have the chaos of my kids in the car. And I can just think for once. And I thought, we should just put together A trio of products. So it's PC balance, oil and liposomal vitamin C. That's your starting place. Start there, take it for three months, look at your skin condition, stop taking it. See if the skin continues like that, because it won't. It's the same effects of PC. People often say to me, I don't necessarily feel PC. Well, it's the same people that are probably. They're not tuned in to what's going on in their body necessarily. And then they stop taking PC and they. A couple days later, they have brain fog.
B
Yeah.
C
And then they say, oh, it was the PC. I got to start taking PC again. And it's very similar with the skin Cell essentials trio. So it's three products together. Easiest place to start. You're getting those lipids into the body that are feeding the, the fat content, the healthy fats, and the bioactive lipids that our skin needs. And then you're helping with the collagen synthesis that's bringing it all together from vitamin C. And typically a lot of us don't have enough vitamin C in our bodies.
B
Yeah, 100%. How. How would you. So I'll give you an example when. For. When I have injuries due to Jiu Jitsu, I don't want Jackson to hear the producer because I'm pushing him to. To Jiu Jitsu. So Jackson, I never get injured, by.
C
The way, but I've been trying to.
B
Tell my husband, he's like, no, hypothetically, when I get injured, is he also doing Jiu jitsu?
C
Our son is the oldest one is.
A
Yeah.
B
Okay. So. And of course, he never has injuries.
C
No, not yet.
B
But how. So, for example, when I do get. Get hypothetically injured, I really ramp up my vitamin C. If it's a ligament related, I really ramp up my vitamin C intake. And I do it in a way where I take it multiple times a day. So I.
C
So there's less because it doesn't last in the body.
B
Yeah. Does there's less gut irritation for me specifically, my gut doesn't like when I.
C
Do you take ours.
B
Yeah. But does it affect your general. My, my gut would react to, let's say more than 5%, my more than 5 grams creatine, for example. Like my gut really doesn't. Doesn't like instability or irritants or things like that.
C
Interesting.
B
So I really take it like four or five times a day, for example, things like that. So how would someone push the envelope in the example of vitamins?
C
The biohacker.
B
The biohacker. If one is good. You know, probably 1,000 is better.
C
Yeah. So, yeah, there is no upper limit of toxicity. Look, you take too much PC or balance oil and you're gonna have diarrhea. It's not the end of the world. But we're talking like six tablespoons a day, so I take two tablespoons of PC a day.
B
Me too.
A
Two tablespoons. You take one at least I take one. We talked about it in the podcast before. He has to run after me with supplements. I'm not very diligent, but I'm grateful. But he put him by your vanity.
C
And first thing in the morning, just kind of take a little chug.
B
Yeah, no, listen, she has me to.
C
Follow her with the spoon and we.
B
Have to hide the PC. Remember?
A
That's because of our son. He's asking for more and more. We had to, like. That's the problem of, like, having it out for yourself to remind yourself, but then, you know, reminds him. But. Sorry, we interrupted. You were saying.
C
Same with balance oil. You can up it. I think it's great for you. Never want to heat it. So balance oil. I'll make a salad dressing. So I'll do a little bit kind of dash of olive oil just for taste. And then the rest of it's balance.
B
Oil and it tastes fantastic.
A
He actually adds very mild to Italian salads as well.
C
And I put it in mashed potatoes. Pour it on top kids foods. Pour it on top kids. I make them a chocolate milk every morning with a chocolate protein powder. We do balance oil. Remineralize Elite and the kids. For the kids, raw milk.
A
I love Elite.
B
I want to get those, actually.
A
I'm so sorry. I was doing my skincare routine the other day, and we have to wait for our vampire exosomes. We have to wait for it to fully absorb and we ask just, you know, to wait between five to 10 minutes so it's fully absorbed. I usually wait like three, because I can tell when it's absorbed.
B
Not.
A
And I was like, I'm going to put my Elite in the water and I'm going to take it. Like, in the meantime, I'm just going to drink some water, you know, something useful. Yeah.
C
And just drink your minerals. That's a great idea. I'm going to do that. I need that product.
B
Oh, I. Yeah, it's. This is the best product we've ever made.
C
Anyway, I'm excited.
B
Oh, yeah. It's incredible. But so I do want to go one by one because I think.
C
Oh. And then wait. Yeah, because we Forgot, like the upping the dose.
B
Yes.
A
Yeah.
C
Every four hours you could do two to four capsules of vitamin C, up to 4,000 milligrams. And then the last one, I would say that's really interesting.
B
I might push it to 10, by the way. But don't be me.
C
So now if you want to, for after injury, for Jiu jitsu, you should try resolvin, which is our fish oil. But it's phospholipid, it's caviar, it's herring roe, cold pressed teal. So it has the SPMS in it, which are incredible. Unbelievable studies that have been done on psoriasis and eczema using this. Now, I would not take it every single day. I'm not a fan of fish oil every day. That's why you take your balance oil every day, couple times a week, add in fish oil, eat as much fresh fish as you can, See if you are having a skin autoimmune condition, or if you are having joint pain, or if you are having muscle pain from going too hard at jujitsu, then you can up your resolving.
B
And you're saying you're not a fan of fish oil every day because of the anti inflammatory effects of it.
C
Yes. After long term effects it will start to act as a steroid. But the other thing is it offsets the omega 6 and omega 3 ratio in the cells and you still need those omega 6s. So let's say you are really into health and wellness and you're super anti seed oil. You're not even, I mean the really crazy ones aren't even eating egg yolks because they're too high in linoleic acid. We need linoleic acid.
A
We need egg yolks.
C
You need egg yolks. You need these. These are superfoods for our mitochondria. You need linoleic for the cardiolipin production within mitochondria. So I just like to have a good balance of those sixes and threes, which is why I never say fish oil every day.
B
Interesting.
A
I have a question and then we gotta get into the rapid fire.
B
But we're not done with the protocols at all. I have so much to know now.
A
Okay, so. So go with the protocols.
B
No, I'll do it in the rapid fire.
A
Okay. Okay. So one question I had, and we kind of always tend to ask this when we bring someone like an expert in their area. Are there any mistakes that someone can make when they're excited to take up like this challenge of, you know, supplementing for skin care from within. And what are the common mistakes that you see people make?
C
If you're doing the higher dose, if your gallbladder and your bile function are not optimal, you can definitely get that nausea. Have you ever had that kind of nausea where you need to eat too much fat or eat eggs? Yeah, that's gallbladder stagnation. And so you need to make sure your bile flow is working. Which is why if you have a history of gallstones, if you have a history of gallbladder issues or your mother, father had their gallbladder removed, make sure you're doing some tadka or taking something like ox bile or tadka with your healthy fats like PC and balance oil so that you are getting the right amount of fat and that fat is actually getting absorbed through the liver and the gallbladder so you can kind of get that.
B
Would you do tadka together with. If you're taking PC and balanced oil anyway? Would you?
C
Yeah, I do. I do.
B
Yeah.
C
It's such a, has such great neurological benefits as well.
B
Okay. So I want to run through, we'll do it like a rapid fire but I'm going to run through a few, a few like maybe points of interest.
C
Right.
B
And you know, just people can read the back of labels. People could, could ask, you know, chatgpt the, the protocols if they really want to. But back of labels are great. Someone is interested in anti aging. We said the three, the top three are, are vitamin, liposome, vitamin C, PC and balance oil, right?
C
Yes.
B
Okay.
C
What about skin or for brain? For, for skin, those three in the bundle.
B
What about if someone has, you know, pigmentation has issues with you know, things like again glow pigmentation, things that are more pigment and, and oxidative, stress related. More vitamin C. More vitamin C. What about the glutathione? Is it, is it.
C
You can also do. Definitely.
B
What about if someone has acne?
C
You need the tadka liver. You got to add in tadka. You probably want to up your PC.
B
Yeah. Maybe vitamin C for just because it's.
C
I think it's important but I think a lot of hormonal acne in particular is, is that liver is backed up, it's not processing the hormones correctly. You maybe you have a history of being on hormonal birth control, something like that that is causing those issues. Get that liver moving, flowing. Tadka is like your liver enzymes just immediately go down. It's incredible.
B
Okay. Pregnant or postpartum and you know, within the confines of skin support, PC balance.
C
Oil, vitamin C All safe postpartum, not during pregnancy. I think those are three super important supplements for pregnancy, mainly PC and balance oil. Postpartum, you're going to add in when you're breastfeeding, do it once a week, some tadka. When you're done breastfeeding, you can do tadka for a month. Get those livers, get the hormones detoxified from the liver properly. Great combo.
B
And then the last one is pre and post procedure. Let's say someone is again like even though I poo pooed it, it's still true that you should do, you know, once every month. Your, your micro needling or whatever that is, you know, if you had surgery, if you did this, that or the other, you know, you've introduced some injury and some assault to the skin. How would you support it? Kind of, how would you prepare for it and how would you support it afterwards?
C
So pre, they're going to tell you to stop taking any type of fish oil and that includes something like balance oil which is an omega 6 and 3 that's for blood thinning purposes. You can continue to take PC, you can take vitamin C beforehand and I would also take glutathione afterwards. You're going to want to take high dose PC. Get back the. Particularly if you were under anesthetics, you're going to want the benefits for your mitochondria. High dose PC, balance oil, glutathione, 2 in the morning, 2 at night, vitamin C and add in resolvin, that fish oil that we make because that is super anti inflammatory and has the naturally occurring specialized pro resolving mediators and those are what go into the source of the inflammation and just put the fire out. They're incredible.
B
And resolving for your. And that's the last one. And then you know we're going to go to legit fire, not like pirate rapid fire questions. And resolving as a, as a, as a longevity strategy. Would you say once a week? Like how often would you say.
C
Yeah, one to two times a week. It depends on how often you're eating fish. You guys probably fish a decent amount here.
B
I did a wonderful pate.
C
I know.
A
I was going to say he just did a sartine pate the other day and it was.
C
Honestly love that.
B
Thank you.
C
Anchovies.
B
Yeah, yeah.
C
Caviar when you can. Oysters. Yeah, they're all superfoods.
B
Nice. Okay, you can go.
A
Okay, I can go with the actual rapid fire questions. Okay. So these ones you answer like in a rapid manner and those make great for like Instagram clips.
C
Okay.
A
Okay. Coffee first thing in the morning. Yes or no.
C
And why no blood sugar regulation benefits.
A
Okay. The one wellness trend you think is completely misunderstood right now.
C
Sea moss. It's the most ridiculous thing I've ever heard. Yeah, just get your minerals from some minerals. Why are you eating the sea moss that is mostly grown in pools and it's completely contaminated? I'm not a fan.
A
Okay. I love that you brought up. We didn't talk about it in the podcast, so that's great. The supplement, you won't travel without PC. Okay. Yeah. I just mentioned that I traveled recently without it, so, like, I'll learn from you. Okay. Your current favorite daily skin ritual that has nothing to do with skincare. So no topicals.
C
Oh, I'm a skincare junkie. So my like wind down routine at night, this is not a rapid fire, but I could really go into this. I do like red light. So I am using the therabody face mask. I'm trying to use it every day, but that's hard. I put my face in cold water in the morning, first thing in the morning. That's not skincare. What else? You know, the other thing I think that we overlook that's really important is circadian biology and getting your eyes exposed to sunlight, no sunglasses, first thing in the morning. I think that's really important. And I also think sun for skin. I think it's important for skin health.
B
To support what you're saying. One of the surprising ingredients that we see contribute to hair growth and a lot of the times, by the way, these two are linked, hair growth and skin health is melatonin. Topical melatonin.
C
Exactly.
B
Because it cues, basically kind of sinks your circadian rhythm. So people putting it at night, cueing your. Their hair follicle to basically go into repair or regeneration mode. Yeah.
C
Yeah.
A
Okay, we got three more. One sign your cells are inflamed, even if your skin looks fine.
C
Any type of chronic illness, any type of. I mean, I hate to say this, but brain fog, fatigue, headaches, all of that.
A
Yeah. Okay. The biggest misconception people have about omega 3s.
C
Oh, we're fish. Everybody thinks we're fish. Take omega 3s. It's super important. DHA is very important for our brain, but the proper ratio in our cell membrane is four to one. Four part six, one part three. And if you're not out there eating fried foods and a ton of canola oil, I would argue you are most likely completely deficient in omega 6.
A
Yeah. Wow, that's major.
B
But the average American, I Think they have a one to six ratio. Right.
C
How did they do that testing?
B
That's a good question.
C
Who are they testing?
B
Yeah.
C
And also, are they doing plasma testing or are they looking at the red blood cell fatty acid analysis plasma testing? Most. Most tests out there right now are looking at blood plasma levels of what you have eaten in the last week. So if you didn't eat any fish in the last week, your ratio is going to be completely skewed. So when you look at a red blood cell fatty acid analysis, it actually looks at the cell membrane. Oh, it's looking at years. And it's looking at the overall structure and fluidity of the actual cell membrane. And that is where you really see Omega 6 deficiency show up.
A
Okay, I have one last question. Beauty from within. Is this the future of skincare and will it replace the skincare?
C
No way. No way. I think it's a combination. You need both. I think we really need to start looking at both. You have to think really carefully about how we're nourishing our bodies, but also what we're putting on to take care of those things, particularly as we age. I mean, it's a huge thing for me. You know, you're looking in the mirror and you see everything. I'm 42 and I'm like, what am I? You know, what's next? I'm doing all the lasers. I'm doing all of these things. I think topical skincare is part of it. I don't think you can abandon it at all.
B
Yeah.
A
Thank you. Yeah, I love that.
B
That was great.
A
Yeah.
B
Well, let's end up by saying, you know, we talked a lot about your products. Obviously we're junkies, so it's easy. How does someone, you know, start their journey? Where is it best? From your experience? Where do you get your products? Yeah, in the. The shortest, you know, kind of supply chain way. Because that is also something to consider. Right? Like how. How fast from point of production to the words, you know, for example, in the balance oil example, where it's in my fridge. Right. What's, what's the. What's the best way to order products.
C
From our website directly is always best. Bodybuyer.com we ship internationally through bodybuild.co.uk we do sell on Amazon. So if you're a crazy person who needs your product the next day, day you can get it on there. Just make sure the seller is body bio because there are fake products and unauthorized resellers showing up all over the place. And if you have any international Listeners. Iherb. Iherb is a really great way to get things into other countries.
B
Yeah.
C
That we don't, you know, have the proper labels for or something like that. So that's also very easy.
B
As the famous saying goes, the best compliment are fake stores on Amazon.
A
Yeah.
B
And fake Chinese companies trademarking your brand in China. These are the two. Oh, yeah. For sure. The two. The two best, by the way, compliments that I can receive.
A
But on that note, of international listeners, we recently looked at our statistics and we have 55 other countries besides the US listening to us. So thank you guys. It's so fun. And thank you.
B
Gracias. Gracia.
A
I think it's one of the. Yeah, I learned it today because I got my hair done with the Turkish. What did I want to say? So on that note, we also want to announce a little milestone that our podcast hit. We are officially number one in beauty and fashion. Thank you guys so much.
B
And then what did we do? We went away from it.
A
Yes. Amitai is. We also just switched the category to alternative health, where we are ranking seven.
C
So.
A
Which is also really fun to be in top 10. But we do need your continuous reviews. Those help so much. And we've been getting so many of them. And we have a little tradition where we read.
B
Oh, that. I just love the best tradition of all times.
A
Yeah. Where we read the review and thank you for your view and send your product.
B
Oh, so, yeah, they get a free blue peptide spray. Oh, yeah.
C
Nice.
A
I'm going to.
B
Do you want me to do it?
A
Sure.
B
Okay. I'm just going to choose a random one. Is that how it goes?
A
Well, it's whatever you want. You can. Sometimes I do the most recent one. Sometimes I Actually, when I have time, I do read them all. But sometimes in the moment, like now, I go for just the one that.
B
So I'll tell you secrets. Okay. You can't. If. If you just go to the thing, it's not going to give you the recent ones. It's going to give you like a. Like a popular one or something. I don't know about top viewed, but.
A
Like, how is it popular?
B
I'm gonna choose it by name. I'm gonna go with. Wow, that's a cool one. Aria in the sky with Diamonds.
C
Oh, yeah.
B
The conversational tone of this podcast makes the science of skincare easier to understand, even if you're new her to the idea of skin longevity. I've recommended it to several skincare newbie friends and they love the more approachable tone. I Love that the hosts don't always agree on every single thing. It creates a thought provoking, provoking dialogue. Maybe that's what our son's like looking at us arguing like. I love that the hosts. I appreciate the minimal small talk and the straight talk about which skincare trends may be nothing more than trends. This is the only skincare podcast I impatiently await every week.
C
Oh, that's wonderful.
B
That's very nice of you. Aria in the sky with Diamonds.
A
So, yes, you can either email service.com and we'll send you your product or you can DM us on Instagram. And thank you, Jess, for staying for this moment. Thank you so much for coming.
C
Thank you.
A
It was such a. Lovely to chat with you and I love your products.
C
I love.
B
Yeah. So what about the review on the Apple?
C
I'll leave you a review. I use the whole hyperpigmentation kit. But now I need. I need some new products. I need.
B
Oh, you're gonna. I'm telling you, the. The Vampire Exosomes. You know, here's the thing. I love recommending the bulk peptide spray because it's affordable. Everyone can afford it. However, you know, and I love that product. It's an amazing product. However, Vampire Exosomes is by far what gave me the best results. It's like so nicely recommended. Anyway, love it. Jess, we've been to. Just to summarize it, we've been using your products for the longest time.
C
Thank you.
B
Way before we knew you. We believe in what you are doing and we are so, so grateful to know you personally and have you on here.
C
Thank you. Same to you guys.
A
Thank you. Bye bye, everyone.
Podcast: Biohacking Beauty: The Anti-Aging Skincare Podcast
Episode: Jess Kane (BodyBio): How Omega Ratios, Low Fat Diets, and Damaged Cell Membranes Trigger Skin Aging
Date: February 11, 2026
Host(s): Anastasia Hojaeva (A) & Amitai Eshel (B)
Guest: Jess Kane, Co-owner & CMO of BodyBio (C)
Theme:
This episode explores the crucial relationship between internal cellular health—especially the role of fats in cell membranes—and visible skin aging. Jess Kane dives into why advanced skincare can't deliver optimal results if the body's cellular building blocks are ignored, unpacks the widely misunderstood omega fats debate, discusses why most liposomal supplements don’t deliver, and shares practical advice and protocols for anti-aging from the inside out.
Start with:
Test results for 3 months, then pause to see the effect.
Quote:
“Start there, take it for three months, look at your skin condition, stop taking it. … They stop taking PC and they … have brain fog. … It’s very similar with the skin.”
— Jess Kane [38:13]
How to “push the envelope”:
“Human beings are really not well built to measure or intuit incremental change. If it was, McDonald's would have been out of business.”
— Amitai Eshel [04:08]
“Why does my skin look so good? Why do I feel more, like, refreshed?”
— Jess Kane, on what users say after a month on foundational protocol [10:23]
“There is no upper limit of [vitamin C] toxicity. Look, you take too much PC or balance oil and you're gonna have diarrhea. It's not the end of the world.”
— Jess Kane [40:40]
“If you're eating healthy, not frying in canola oil, you are most likely completely deficient in omega-6.”
— Jess Kane [51:16]
On beauty from within:
“No way. No way. I think it's a combination … I don't think you can abandon [topical skincare] at all.”
— Jess Kane [52:26]
Advances in skincare matter, but only when built atop strong cellular “scaffolding”—the phospholipids and essential fats making up your cell membranes. Extraordinary skin starts from within, with high-integrity ingredients, ideal omega ratios, and real liposomal nutrients. But topical routines still play an important role: longevity is holistic.
For more protocols and details, download the Winter Skin Protocol from the episode description.