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Amitai Eshel
Foreign welcome back to Biohacking Beauty. I'm Amitai Eshel, your host, and today we have something special lined up for you. We are repurposing an amazing conversation from your Longevity Blueprint, where I had the honor of being interviewed by Dr. Stephanie Gray. In this episode, we dive into the intersection of skincare, biohacking and longevity. Dr. Gray and I explore how skin is a key indicator of overall health, the science behind aging gracefully, and how biohacking strategies combined with innovative skincare, like what we create at Young Goose, can help you achieve resilient, youthful skin. If you're curious about how your lifestyle choices impact your skills skin, or if you'd like to discover cutting edge approaches to enhance your skincare routine, you are in the right place. So let's jump right in and explore how biohacking can unlock your beauty potential, courtesy of this special episode with Dr. Stephanie Gray on youn Longevity Blueprint.
Dr. Stephanie Gray
Welcome to another episode of the youe Longevity Blueprint podcast. Today my guest is Amitai Esho, who is an entrepreneur in the biohacking and beauty fields. He has held executive roles in the health, wellness and beauty industry for over a decade, as well as being a business development consultant in that space. As co founder and CEO of Young Goose, the biohacking skincare company, and host of the Young Goose's Biohacking beauty podcast, Amitay has been making waves in the industry through education and innovation. Young Goose embodies his two passions, performance optimization and skin health, with products that boost the functions of natural rejuvenation processes in the body. Welcome to the show, Amitai.
Amitai Eshel
Thank you so much. The first person to ever say my name correctly, so gives you a lot of credit. That's harder than medical school.
Dr. Stephanie Gray
I only said it correctly once, but I will try to pronounce it correctly the rest of the show.
Amitai Eshel
That's great.
Dr. Stephanie Gray
Thank you for being here.
Amitai Eshel
Absolutely. It's absolutely my pleasure.
Dr. Stephanie Gray
So for listeners who follow me on social media, they know that I was very excited to announce that my practice, the Integrative Health and Hormone Clinic, was really the first clinic here in Iowa to be able to retail your products. These amazing products. And I learned about them from actually some of my past podcast guests who are biohackers. You know, they're in that industry who love their products. So for my listeners, you know, Natalie Knitten, Sean Wells, and I even saw recently Amy Horneman was, you know, advocating for your products. So I know that will sound familiar to listeners. So, uh, additionally, you've trained our staff on these products. And I thought, well, what better way to educate my patients and listeners on their benefits than bringing on the expert and the creator? So today I want to dive into the products, but first I want to dive into how we really can reduce skin aging. So let's, let's start with that. And I always like to ask my guests their story. So, yeah, you know, kind of tell me the story behind the story, kind of what led you to starting your company. Before we really get into how to.
Amitai Eshel
Biohacker skin, I think my story is, is not, not. I think most people that look into, into health and wellness come from a, from a point of, like, from a low point. They had some, some history of some, something, some event that, that led them down that path. And for me, it's more of a nerdy path, to be honest. It's more about being really interested in, in how to optimize my running away from pain, rather going towards pleasure if to, to use some Tony Robbins anecdotes here. But yeah, I, I started my, my first career was in the military. I was in Israeli special forces. Head of recon for, for a special forces unit in Israel. And when I got out of the military, obviously that's a lot of wear and tear in the body. I wanted to continue to redline my body. I'm, I'm, I'm, I'm very interested in, in, in sports, wrestling, jiu jitsu, whatever that is. And obviously a lot of injuries in the military, some wear and tear. I really wanted to perform my best. So that was one kind of introduction into wellness. You know, treating your body a certain way, some would say like a temple, but that's one aspect. The other aspect is I got into this one of these, the really early on red light therapy companies. It was actually a laser. And our project was really to make a consumer product out of it. And what I realized is that you take this medical laser and you know, you make, you make a panel out of it and you're trying to explain to people that it can reduce pain, that it can improve performance, blah, blah, blah, and the sales weren't going that great, to be frank. But then when some discoveries and how it can improve skin health came out and we started to, to use this rhetoric, we found out that, you know, a lot of people, that's where they want to see a difference in their health journey in their life. And that was kind of a, kind of a eureka moment for me as far as me understanding that where my ego is, is, is lies as if we would, is how My body performs. But for a lot of other people, it could be how their sk. How their mirror performs, for that matter, how. How they look when they look in the mirror or today it's when they get. When they post something on Instagram or whatever that is. Right, TikTok, whatever. But really, everyone identifies with their. Identifies success as far as their health journey in a different way. So I think that that's kind of the two ways that I got introduced into biohacking, health optimization, whatever that is, whatever you would like that along the journey, I fell in love with nad. Fell in love with nad. IVS understood that this is something that is very costly and we tried to find a way to make it cheaper for people. So we tried to get it. To make it a transdermal application of NAD precursors. Unfortunately, or fortunately, we found out that the skin really likes it. You give the skin nad, even if it's small enough to absorb, and the correct makeup to absorb the skin keeps it. It doesn't want to share. So we made lemonade out of lemons and we made a skincare product. And I'm sure we're going to get into it, but what we found out is that we can have the skin behave significantly younger. Unfortunately, unless you have an underlying condition, unless you are. Unless there's something going on that the skin is engaged in addressing, the skin doesn't know a wrinkle is a problem or a pigmented area is a problem or laxity is a problem. And we can go on and on. It doesn't know that there's no signal that says, hey, please repair this. So the second phase of the company, if you would, was looking at signals, was improving signals. How do we communicate to the body that we need it to repair? Fill in the blank, whatever that is. Right? Yeah. Yeah. So that's kind of the journey of me and Young Goose in a nutshell. And I've had some other projects within the biohacking space during that time, within the longevity space. We consult a lot. We develop different processes, projects for different people. But this is our baby. Mine and my partner, Anastasia, which is really the. The heart and soul of this company.
Dr. Stephanie Gray
Well, part of me wants to go off on a big tangent and ask about your experience with being in the Israeli special forces and kind of like if there were any special secrets that. That you were taught to help improve performance. But I feel like that could be a whole nother show.
Amitai Eshel
Yeah, I'll just say mainly breathing, I think, you know, during stressful situations, civilian, whatever that is. Yeah. We realize that breathing is one of the things that changes our state the most. So, you know, really, to make sure that we. That we don't get go on a completely different discussion here. What I would say is, is that if you learn to manipulate breathing, you learn to manipulate your body, whether for better or for worse. And I think this is a huge part of. I think there's a difference between how you feel right now and longevity. And a lot of times they don't actually connect. But I think this is a good way to improve both.
Dr. Stephanie Gray
Thank you. Yeah, we'll leave it at that and go back to skin aging. So how does skin aging drive whole body aging?
Amitai Eshel
That's an incredible question because normally what we were used to think of is that the better we treat our body, the better our skin looks. And it is a hundred. It is true to a point. What I would say to that specific subject before I go to the mirror side of it, which is how the skin affects whole body aging, I would say is as we grow older, especially women after menopause, but as we grow older as a whole, the skin becomes less and less a an organ that communicates sexual maturity, vitality, etc. And it becomes more and more an organ that protects the body from the environment. It becomes more of more a shield that is being sacrificed in order to protect our body, rather than an organ that is supposed to tell the environment, hey, I am at my peak and I'm a valuable member of society. I'm a youthful, vibrant individual. And I think that there is something there as far as why we want to look, why we want our skin to look good as we grow older. Because that is really the communication method for, hey, I'm a productive member of this, of this society. Having said that, looking at the opposite side of it, looking at how what happens in our skin as we grow older, and I'm sure we're going to go back to it when we talk about NAD and senolytics. But what happens is that lack of ability to repair leads to a lot of waste, debris, and especially cells that are malfunctioning. Chief among them cells that are called senescent cells, which you can think of them as zombie cells, are normally what people call them, and that's very apt because they don't communicate, they don't contribute, they infect other cells, and they are basically in a state that's between living and dead. But we can really think of them as malfunctioning cells. And these cells create a lot of inflammation. This inflammation obviously Is bad. Okay, we can talk about why inflammation is bad, but really, inflammation is a driver of aging. It's called inflammaging. And this is one of the major culprits of why our body ages. But as I said before, the skin is a communication organ, not only towards the outside, but also towards the inside. If you think of it, this is what stands between your body and the environment. So a lot of the environmental cues that our brain receives, it is received through our skin. To give a shorter example, that's maybe not connected to what we're saying, Studies show that if you put on an eye mask, you won't be able to see any light at all. But you go to sleep in a lit room, your sleep is going to be disturbed because your body receives, your skin receives some of that light. And obviously, you know, your skin creates hormones, creates vitamin, vitamin D3. There are many things that we can talk about the skin and its ability to communicate to the brain, but it's kind of a, to use a military term, it's kind of a term, it's kind of the tip of the spear as far as your brain is concerned.
Dr. Stephanie Gray
Yeah.
Amitai Eshel
And that is called the skin brain axis.
Dr. Stephanie Gray
As you have that one. I haven't had the skin brain access.
Amitai Eshel
Okay, so your skin communicates directly with the a HPA axis, hypothalamic pituitary axis, and this, the, the HPA axis is responsible for stress response in the body. And when we grow older and we accumulate those senescent cells that create a lot of inflammation, they actually send inflammation, I'm using heuristics here, but they send inflammation to the brain. They also infect different cells, like, you know, cells that come in contact with them, such as immune cells, blood vessels, etc, but they infect the brain with inflammation, infects the HPA axis, the hpa, excuse me, with inflammation, which then communicates stress to the body, elevates cortisol. Obviously, when the brain is inflamed, you can, you can, you'll be right to assume that you're the rest of your body in the inflammatory burden in the rest of the body grows. So by having an older functioning skin, we are not, you know, a lot of people say maybe rightfully so it's not a saying that I, that I would battle against necessarily. I earned my wrinkle. That's fine. If you, if you have. That's, that's not necessarily a bad thing. But earning senescent cells is definitely bad. Earning malfunctioning cells are definitely bad because you are earning inflammation. And that inflammation obviously communicates to your brain and that inflammation ages you. It creates brain fog, creates a, A, a different hormonal response which is negative, which, which is kind of a self feeding loop because more inflammation begets more senescent cells, etc.
Dr. Stephanie Gray
Well said.
Amitai Eshel
And now you got an hour and a half lecture in in five minutes.
Dr. Stephanie Gray
Well, so yeah, so what are some. Given all of what you said, right. Which we don't want to have happen, we don't want our skin to age. We don't want that inflammating. What are strategies to reduce our skin's functional or biologic age?
Amitai Eshel
So first of all, you know, and I'm going to go back to that, that saying that the better we treat our body, the better our skin's going to look. Most people wouldn't don't know that around only around 20% of skin aging is what we call intrinsic aging aging that happens from the inside. 80% around obviously it's individual. But in Western society, 80% of aging is from external factors, extrinsic aging. So it could be pollution, it could be toxins, it can be heavy metals, it could be obviously UV light and blue light that we get from artificial light, which is called high energy visible light. All of those things drive skin aging and they're normally in western society is about 80% of what skin aging is. So first and foremost, prevention. An ounce of prevention is what, what do they say? An ounce of progression is like a pound of cure.
Dr. Stephanie Gray
Yeah.
Amitai Eshel
So that's number one, definitely protect our skin. And we can do it in a few ways. We can obviously do it through natural or non chemical sunblock and some peptides that can help with us protecting our skin. And we can also do it with antioxidants in our products and also from the inside. But in general, studies show that we can double the effectiveness of an, of a sunblock if we add antioxidants to it. Just to give you an idea. Wow. Yeah.
Dr. Stephanie Gray
So in general, does your sunblock have antioxidants in it?
Amitai Eshel
Not only antioxidants, also very, very interesting peptides that we use to help the skin repair its cellular membrane like super fast before, before that damage accumulates. It's actually extremely interesting. So we don't, we don't only protect from. And that's why people like, you know, Molly Maloufa or Dave Asprey and all of those people really like our, our sunscreen because it doesn't only protect you from uv, it also protects you from blue light. From pollution and from, and helps the skin deal with the damages of emf, which is electrical magnetic frequencies that we're all exposed to that also damage our skin. So that's number one, prevention. Number two, how can we lower the functional age of the skin? First and foremost, we can serve the skin the molecule that it lacks as it grows older. That kind of is the culprit of everything that we think of as aging, which is nad.
Dr. Stephanie Gray
I knew you were going to say that.
Amitai Eshel
Of course. Yeah. NAD is basically the fuel not only for energy creation, but also for over 600 repair processes for DNA integrity. So for many things that are, that we think of as correct function or youthful function, as we grow older, NAD halves by the time we get to 60, and that is. And we can think of aging as the accumulation of unrepaired damage. So NAD is essential for damage, for damage repair. And every time there's not enough nad, we accumulate that damage and eventually that leads to aging and even death and disease. Death.
Dr. Stephanie Gray
And just for our listeners, we talk a lot about mitochondrial health and mitochondrial function and NAD is just absolutely necessary for that, just so that they can. Yeah. Kind of understand more of what you're, you're saying.
Amitai Eshel
Yeah. And I would say this, that's something that, that, that normally drives in the point. If I took NAD magically from your body, you're going to be dead in 30 seconds. Okay. So I think that's a good contrast to paint. Right. So unfortunately, if I try to give NAD to my body, to my skin, the body doesn't really understand what to do with it because it only exists inside our cell or it's only utilized inside our cell. What the body is used to is recycling its own NAD and using different types of vitamin B3 as building blocks for NAD. So normally what we want to do is give the body different types of vitamin B3. There are ones that work better, better and worse. Normally what people know, especially from skincare, is niacinamide or non flush niacin. I would just. This is a whole, this can be a whole podcast, but let's just say it's the least effective form and it can be detrimental. So normally what we want to give the skin is like really high performing building blocks for nad. They are called nr, nmn, mn, tryptophan, na. All of those are normally the ones that we want to look for. Sure. And guess what? We have all of them in our product. So this is the first and foremost. We have to raise NAD levels and we have to signal DNA repair that's how we can have the skin behave like a younger skin. So we do it through patented form of resveratrol which, which is. You can think of if, if NAD is the, the fuel for repair, especially DNA repair. Resveratrol is like the gas pedal for that repair. For DNA repair. Okay. So normally resveratrol is not very bioavailable in the skin. We have a process that makes it 50 times more bioavailable. So this is really. And by supporting with, with CoQ10PQQ, things like that, different peptides, we can have the skin behave like younger skin. We have them in two products which are kind of our base products that we believe everyone in the world should use, which is Care, our moisturizer.
Dr. Stephanie Gray
Go into those. Yeah, go for it.
Amitai Eshel
Yeah, Care, the moisturizer and eye care which is for, for the skin around the eyes. A little tip. You can also use it around the lips. That is the two products that I'd recommend the most, which I've been doing.
Dr. Stephanie Gray
Since you told me. Can you. Can you see this is better. Those have the n. I do call that the NR Noble.
Amitai Eshel
That patent we actually are changing. We trademarked it a little differently because people now don't really know what NR is since David Sinclair, the kind of Harvard longevity expert has really hammered in other building block that's called nmn, which we also have in that. In that. In those products. So now the trademark is called NAD Noble. So we're going to phase out NR Noble, but it's more familiar with.
Dr. Stephanie Gray
Yeah, sure, sure.
Amitai Eshel
Yeah.
Dr. Stephanie Gray
That's in the care boosting moisturizer and in the eye care and the eye cream.
Amitai Eshel
Yeah. And these building blocks are special because they're nano sized and they're liposomal. So there is like a protective layer on them so they, you can get them the freshest and the most active when they do absorb into your skin. If we wanted to have the skin specifically behave like a younger skin, we also need to eliminate those senescent cells. Right. And that we do through pro Care serum. So remember, care and eye care are really that fuel for repair and our serums would be the signals, the different signals for repair that we can have. So Procare is signal for overall anti aging. It will treat wrinkles, sunspots, rosacea, it will balance your oils, things like that. But it's a more general anti aging signal. It reactivates 14 different genes that are involved that lower with again with lack of nad, such as collagen genes, elastin genes, hyaluronic Acid genes, things like that. But this is really an overall longevity system. Right. We have Procare serum, we have care and we have eye care. What we could also do, we can also eliminate things that gobble up NAD as we grow older. One of them is called the CD38. This is really nerdy. Most people are never going to talk about CD38, but CD38 is. Is this enzyme that basically destroys NAD. It's like a PAC man for NAD as we grow older and we have a lot of those PAC men as we. As we. Or is it PAC women? I don't know, they changed the game. But anyway, as we grow older, we have more and more of that, then that depletes NAD as well. And a very cool little active that's called apigenin. That's what makes you sleepy. In chamomile. In chamomile. That's what eliminates CD38. So we have it in our adaptogenic cleanser. Yeah. And one of the things that I say about this cleanser is because it has those active ingredients, again, peptides, which peptides, you can think of them as like little keys to different. They unlock different mechanisms. Right. So how you leave it on the skin for like 2 minutes, probably 10 seconds are enough. But I shave with it as well. I make sure that I do other things and that's on my skin to really eliminate that CD38 and activate some. Some pathways.
Dr. Stephanie Gray
You shave with a cleanser, Is that what you just said?
Amitai Eshel
Yeah, yeah, I do a few things that you can do with this cleanser which are pretty cool. First of all, is using it as a shaving lubricant. But a lot of people, if they want to do like facial cupping or Gua sha, they. A lot of people don't like the oils that they need to use with it. Some people don't like the smell of those oils. Some people are oily skin to begin with and they don't want to add oils that can accumulate. So you could do that with the adaptogenic cleanser as well, use it as the lubricant for gua sha or facial cupping or things like that. So what we did now is we looked at kind of how do we start the. Our. Our state, our skincare routine? We start with a cleanser, obviously, and we kind of looked at the end of the routine, which is we moisturize our skin. Right. There are a few things that we can do after that, but this is really the two endpoints. What do we do in the middle? So in the middle Is where the the signals for. That's how we kind of customize our routine. That's how the routine can be customized to each and every person individually. And let's say someone has sensitive skin and they want anti aging. Sensitive skin normally means impaired skin barrier, what we call leaky skin skin that allows different things that shouldn't actually be absorbed into the skin to absorb into the skin. It is more sensitive because of it. It is more inflamed. So we actually have a serum that repairs leaky skin or impaired skin barrier that's called bio barrier. It also has antioxidants and amazing as an anti aging serum. But it will be the best for people who have rosacea who have sensitive skin. And we can use different actives after that. But this would be the most important one for that.
Dr. Stephanie Gray
I was just thinking being here in Iowa, in a couple months here we're going to have something called Ragbrai where many individuals bike for a week across our entire state. We're just a big biking state I guess because there's not a lot else to do in Iowa. But I was just thinking this would be a great product for those individuals too. As far as I've heard you say before, this is great for just either cold weather or just being outside, being in the sun. It's great post laser or microneedling or any other treatment because it is kind of that, that shield. So am I saying that right, that those individuals would need a stronger skin barrier? They're going to be outside for a week.
Amitai Eshel
Definitely, yeah. First of all, you, you touched on a good point. When we do any aesthetic procedure, even if we do microneedling at home, what we did now is disrupt the skin barrier and we increased inflammation because the environment inflames our skin. Dust does different, different again different wavelengths. Do the sun pollution, all of those things inflame our skin. So that signal for repair that we created through let's say microneedling or appeal or whatever that is really, it is also inflammation so that there is a lot of background noise. As far as the type of repair that we're asking the skin to do. So to eliminate that background noise, what we can do is we can use the bio barrier, make sure that we isolate the noise, that only the noise, only the signal that we want the skin to signal is being signaled. So that's very important for anyone who's done any aesthetic procedure, anything like that to make sure the results are the best that they can have. And also anyone who is exposed to the elements, you Mentioned.
Dr. Stephanie Gray
You mentioned wind and sun and cold and.
Amitai Eshel
Yeah, yeah, yeah, yeah. That's not true. There are many things to do in Iowa. I heard you build. You build baseball stadiums. I'm kidding. It's the only movie I know.
Dr. Stephanie Gray
Yes. Feel the dreams. Yes. Glad that you recognize it. Let's stay on this product. I know we're kind of going back and forth, but actually let's stay on this product because there are a lot of other benefits of this specific product. You did say it could treat rosacea, but I also like that you. This just stood out to me through our training that this product you said contains. I'm not going to pronounce this right, but the. Like lipochromein 6.
Amitai Eshel
Yeah.
Dr. Stephanie Gray
Which is 20 times stronger than vitamin C. Because I think everyone thinks I need to have a vitamin C serum as a standard in my skincare regimen, whatnot, like. And I. So I was just shocked to hear there was something that was stronger than that.
Amitai Eshel
Yeah. But I think, you know, this is a great point. Vitamin C. Most people think they are. Most people use it in their skincare regimen. Not because it's antioxidant abilities. Is an antioxidant. It's quite tricky. It's very unstable. It is. It's. The conventional types of vitamin C, I would argue are really, really, really bad for you. Or toxic. Ascorbic acid, for example. I would argue no one should ever take it. In my, in my opinion, from what I know. But normally what people are using it for in their skincare regimen is for its sensitizing ability, for its renewal ability because it's. It's basically acidic. So we're gonna, we're gonna separate those two. It's not a great antioxidant. There are. Ubiquinone, adebanone are better. CoQ10, for example, are better antioxidants. Lipochromein 6 is one of the antioxidants that are the strongest in its antioxidant ability. But it's not sensitizing. So it's not going to make your skin more sensitive. For that matter, what is amazing about that antioxidant is that natural antioxidant you can think of like vitamin C only eliminate oxygen free radicals which are natural to our environment. That's what we create. For example, when we create energy, everything in our world really is based on that relationship with oxygen. But because we burn fuel, because we have a lot of different chemicals roaming the air around us, there are free radicals that are not oxygen based. And these are the Ones that really drive skin aging because our body has no ability on its own to deal with them. Free radicals that are based on on nitrogen and especially carbon. So what is amazing about lipochrome is not not only its strength, but its broad spectrum. It also eliminates free radicals that are based on nitrogen and carbon. So it's way more than just saying it's strong. It's strong and broad.
Dr. Stephanie Gray
Okay.
Amitai Eshel
Hey there.
C
This is Amitai, co founder and CEO of Young Goose and host of the Biohacking Beauty podcast. I wanted to take a brief moment to share something really special with you, our dedicated listeners. At Young Goose. We've always been about more than just skin care. We are about cellular care. We believe in not just addressing the signs, but truly diving into the very source of skin aging. The reality is, as time goes on, our skin undergoes damage and this damage accumulates gradually, leading to those signs of aging we all see and know very well. But what if we could hit the rewind button? What if we could delve deep, not into the layers of the skin, but into the life sustaining mechanisms of our skin cells? That's exactly what we're doing at Young Oops. We're pioneering a renaissance in skincare by employing principles from regenerative medicine. By rejuvenating and restoring the cellular function, our products aim to rewind time, gifting your skin a youthful, vibrant glow. And for our Biohacking Beauty listeners, we have a special treat. Head over to Yongoos.com right now and use the code PODCAST10 to get 10% off your first purchase. Discover the magic of truly transformative skincare. And hey, because we value our return customers just as much, use podcast five on your subsequent purchases to get 5% off. And the best part, that this discount can be combined with subscriptions in our already discounted systems. So why wait? Dive deep into the realm of regenerative skincare with Yungoos and let your skin. Thank you. Remember, it's not not just skin care, it's cellular care. And now back to our conversation.
Dr. Stephanie Gray
I swear Dr. Mercola just had something on his social media this week about linoleic acid and your chance of sunburning. And I don't know if you're aware of this, but I'm just seeing, which I didn't notice before, the next ingredient in this product is linolenic acid. So I don't know, I guess here it's saying that it's great to soften the skin whatnot, but I'm wondering if that even improving our. I know he's saying he's talking about ingesting it. But I'm wondering if you have it in this product to also serve as a barrier or protect the skin from the effects on burning. I don't know, maybe I'm making that up.
Amitai Eshel
But you definitely have because you never heard it before. But you are right. But you can think of this, what we tried to do in this product. Again, you can think of every product of ours in two different ways. You can think of it as a product that mimics a process in the body and improves it. And you can think of it as, okay, we're taking a specific product such as a serum. Okay, how do we make it the best there is? So these are two sides to the same coin. But as far as like taking a process in the body and really pushing it to its limit, in this product is that skin barrier production. So what creates our skin barrier, our skin or different cell types in our skin and processes? So as we grow older, these don't function correctly as well. And our skin is supposed to make up its own vitamin F, linoleic acid and vitamin E. Unfortunately, most of the sources of vitamin F in, in our, in our diet are rancid. That's why people tell you don't eat seed oil, for example, don't ingest seed oil. They're highly oxidized. So you are building your skin barrier with really bad ingredients. Really bad. You source your ingredient very poorly, if you would. What we are trying to do is, is to here is to really make sure we create the optimal skin barrier a person could create, but then also supercharging it with that amazing antioxidant that deals with things that your skin never had to deal with before when, when we evolved, what we lived in caves, etc.
Dr. Stephanie Gray
Sure, sure. So this is the ultimate skin barrier. So this is the bio barrier serum.
Amitai Eshel
By the way, a lot of the times when you hear people talk about exposing your skin early on in the day to the sun in order to have better response later on to stronger sun, your body is a heating rhythm standpoint.
Dr. Stephanie Gray
You mean to get out?
Amitai Eshel
Not only, not only. So Dr. Jack Cruz is like a very, you know, kind of built his popularity from interactions with the sun. And whether you agree with them or not, what is ringing true from what he's saying is that if we expose our skin to light that has a lot of red and near infrared, we're going to express more of those natural vitamins, antioxidants in our skin barrier. So, so, so we do improve our how we deal with, with sun exposure.
Dr. Stephanie Gray
Okay. All right. I want to ask you so many questions and I'm not quite sure the best way to go. We could either kind of stay on the product deck or maybe we could go back to questions like what's the best way to tackle wrinkles? And that could kind of help, you know, product to that answer. Okay, so let's start with wrinkles.
Amitai Eshel
Yeah, yeah. Wrinkles, as I said before, really is, is. Is kind of interesting because your, your skin has no idea it's a problem. Okay. And normally what we do is in order to treat wrinkles, we, we basically sweep them under the carpet, if you would, the proverbial carpet. So Botox fillers, right? That's fine. I'm not against that per se. Okay. I'm not saying don't do it or do it, but why? What I'm saying is that you're not changing the fact that your skin has wrinkles, right? That your skin is older. So what we do in Young Goose, we're telling you whether yes or no, what we're going to make sure is that we correct the actual wrinkle. So how do we do that? First, as we said, we have to have the skin be able to deal with them and to create good collagen, et cetera. And a wrinkle really is a valley of collagen, really a depletion of collagen because we moved our face in a very specific way over and over and over again. And it's not breakage in collagen matrix, rather a demarcation that the body couldn't fill. So what we need to do is kind of stimulate repair. And we can do it in two ways. We can do it again. Procare would be a more long term effect. And Procare does have a very, very interesting type of vitamin C that is called thd, which is in ascorbate form of vitamin C, which I would just go ahead and say is better in a much healthier way than ascorbic vitamin C. Okay. 3% of THDs around it is equivalent to anywhere from 15 to 20% ascorbic acid. So just to give you an example, so it's pretty strong as far as its vitamin C content. But what again, what we do also is improve the ability of your skin tool and the actual creation of collagen. So we signal and support that wrinkle and laxity repair. If we wanted specific signaling for renewal there to repair that wrinkle, we turn to retinol. Retinol got a lot of Undue notoriety or a lot of criticism recently, I can tell you that even the most puritan people I talk to, if they do dive into the research, there is nothing there. Retinol is amazing as it, as we kind of, as research in longevity advances, we can actually see that it has some long, incredible longevity benefits. It actually interacts with one of the three major longevity pathways that is called mtor. I did mention sirtuins. MTOR is another kind of amazing longevity pathway. So both Procare and the serum and then not the cream and bioretinol, which is our retinol, they actually work on the MTOR pathway and bioretinol, but really stimulates repair extremely quickly. It does have those, the same qualities of bio barrier which we talked about before, that it repairs your skin barrier so it doesn't only stimulate repair normally. The problem with retinols is that they leave us red, irritated, inflatable because they break down our skin barrier. So by incorporating those biomimetic oils, lipids that we build our skin barrier in, bio barrier into bioretinol, we can actually prevent a lot of that redness. Yeah, so we can do it with two products and or combining them using Procare serum in the morning and bioretinol a few times a week at night. It's still a retinol. We still want to go slowly in the beginning if we're not used to retinols and kind of increase as we go on. But that's a really, really nice system. And that system can also work for pigmentation as well. So we're covering a lot of grounds by using those tools.
Dr. Stephanie Gray
Well, that was kind of my next question, but I do just want to, from a disclaimer standpoint for listeners, just remind them that retinol, retinols are not safe if you're trying to conceive if you're pregnant, whatnot. And then make sure you use a sunblock, which we'll get to your sunblock also. But yeah, my next question was how do we tackle hyperpigmentation? Things like melasma. I have patients ask me about that all the time. And we don't offer aesthetic services here. I mean, we are very heavy on hormone replacement therapy and functional medicine. And so there are things, antioxidants, whatnot, I can recommend for that. But I would love to hear you more talk about tackling that hyperpigmentation.
Amitai Eshel
So first and foremost, we need to improve epigenetics. Right. We need to improve how our melanocytes, that the cells that create melanin Function. So guess what? We're going back to nad. We're going back to supporting that. But as far as, like, really tackling hyperpigmentation as a whole, we do want to do it with Bioretinol Pro and Procare. We can also incorporate another product that is called Naya Polish, which is what, you know. Yeah, it's an exfoliator, and it also boosts NAD levels, which is very important.
Dr. Stephanie Gray
You pretty much all your products boost nad. I mean, that's like.
Amitai Eshel
Well, that's. That's. That we do it with. We do it with a lot of the products, but a lot of them have the relationship between, like, boosting NAD or working within a longevity pathway. It would be. There are mainly three longevity pathways. Ampk, which we didn't talk about yet, MTOR and sirtuins. So we talked about NYE Polish, for example. And ADC works with the sirtuins Procure and bi Retinol works with mtor. And the hyperbaric mask, which is probably our most popular product, actually works with sirtuins and ampk. So we're going to get to that. But basically what we do want to do is incorporate nail polish, starting low and slow again once per week, leaving it on for a few minutes, washing it off, and trying to push it to a few times a week, leaving it on for 10 minutes. And that's going to create an amazing result. Result together with everything that we just said, and actually really create a robust, thick, beautiful skin and skin barrier both. Yeah.
Dr. Stephanie Gray
Awesome.
Amitai Eshel
We could definitely also add the hyperbaric mask.
Dr. Stephanie Gray
That's cool.
Amitai Eshel
There.
Dr. Stephanie Gray
I recently went to. Well, I had IV NAD training a couple weeks ago, and then last week and I went to IV ozone training, and I didn't take your products with me because I just had little travel sizes of another company's product.
Amitai Eshel
Yeah.
Dr. Stephanie Gray
And I. It was so dry there, and I was so spoiled using this new hyperbaric mask, which is amazing. And I came home and I was like, oh, my gosh, I need to use these products again. Because I felt like I had been deprived, you know, the half week I was gone without them. And the mask just, I think, has incredible results. My skin feels so good. I even made my husband use it. He was sitting on the couch, and I said, I'm coating your face with this. You're going to have to stay here for 20 minutes. Got to try this out. Yeah.
Amitai Eshel
I don't know who you take. You get your ozone. Your ozone training from, but if it was simply.
Dr. Stephanie Gray
Yeah, yeah, yeah.
Amitai Eshel
Okay, cool. There Is a. There is one company that they're actually out of Michigan and all of them use our products. So you put it.
Dr. Stephanie Gray
Do they? Yeah, yeah.
Amitai Eshel
Anyway. But the hyperbaric mask is very interesting because the goal is to really mimic, emulate the. The effects the rejuven skin rejuvenation, rejuvenating effects of being in a hyperbaric oxygen therapy chamber, but with a gel that we can apply overnight and get amazing results. So as I said, we talked about kind of the, of the, of the regimen by, by talking about the cleanser. We talked about the middle, by talking about, you know, a couple serums, a few serums that we use. And we talked about the end, which is the moisturizer eye cream. But there isn't. There is another step after that that we can really boost the entire system. There's one for the evening and one for the morning and in the evening. That's the hyperbaric mask. Hyperbaric mask is a gel. We apply it after, after the moisturizer and we leave it on overnight. And what it does, we talked about wrinkles it again. It stimulates our fibroblasts, these cells. If melanocytes create melanin, create pigment, fibroblasts create fiber, they create collagen. So it stimulates those cells. That's number one. Number two, it detoxifies the skin. So again makes it. So it's much easier for the skin to create whatever it needs to create. It activates the sirtuins, helps our skin behave like a younger skin. It activates ampk, which is creating more energy in our cells. It increases the production of glutathione, which is an antioxidant that a lot of people do IVs on. And if it's much better than getting glutathione in a cream, because glutathione smells like botany. So it's much better if we can have the skin created. But as far as. Because of that increased this rush of energy, whatever we did first, we did bioretinol pro care. We boosted nad all of that process, all of that demand from the skin. Now the skin needs to go ahead and create the process that we've triggered. Right? And the hyperbaric mask really supercharges that process. So it really, like if you give this. Gave the skin homework, that's like the Adderall for, For, for your skin, don't take Adderall. But I'm saying as far. That's as far as the mask. But I did say that past our moisturizer there is a. Unless you have questions about the mask. Do you have any questions about masks?
Dr. Stephanie Gray
Well, I would just for the listeners, I was going to say. So it also. It's this. This is applied last, like you said, at night. And if I remember right, when you're saying it, like so, yes. It's actually also supercharging the other products because it's helping those get absorbed more appropriately. Right. So you can either wear it. Like my husband, I was. It was a stretch for me to have him wear this for 20 minutes at night, but I will sleep with it on. Yeah, you can also just sleep with it on.
Amitai Eshel
Yeah.
Dr. Stephanie Gray
And then wash it off in the morning.
Amitai Eshel
Of course. That would probably be the best and probably the easiest as well. What I would say is a lot of people, obviously, if. If someone comes to your clinic and they get a regimen, they're going to follow the regimen. But a lot of people have their own regimen. Right. They find out about us by listening to this influencer or that, and they just want to give our products a chance. A lot of those people are going to start with a hyperbaric mask. And why is that? It's because they don't actually need to sacrifice anything that they're already using. It's actually just going to improve whatever they're already using. And like, by different companies, by different manufacturers, whatever that is. So this is a product that. That plays very nicely with anything else that you're going to use.
Dr. Stephanie Gray
Anything. So relatively speaking, is it safe to apply on top of those products too?
Amitai Eshel
Oh, yeah. Oh, yeah.
Dr. Stephanie Gray
Okay. Just making sure.
Amitai Eshel
Yeah. And it would make them work better. So definitely what I would say is that you should also apply it around the eyes. So it's, you know, most of the times there is a separation in our mind between, oh, it's an eye cream. Use only the eye cream. We apply it over the eye cream as well. Apply it to your neck and chest as well. The back of the hands. So the clinical study we did actually applied it also in the back of the hands. We saw amazing results there. So really, anywhere that you want to have skin rejuvenation, we have, you know, more affluent people that, that buy, you know, them in stacks of like 10 and apply it all over their body. Not judging. Yeah, same. So this is an amazing product to make sure that we. That we really boost the ability of our skin to follow whatever homework we gave it. Sure, yeah. As far as the added product in the morning, obviously we're talking about our bioshield, which is our spf, which is our sunblock.
Dr. Stephanie Gray
Yes. Go there.
Amitai Eshel
Yeah. So the sunblock is, as we said, is very special. Why is that? Is because if you live in a western city, remember I told you 80% is extrinsic aging. Right. It's from the environment. But more of that is from pollution, EMF and blue light than it is from UV radiation. That, that's normally what we get from the zoom is.
Dr. Stephanie Gray
Yeah, yeah, yeah.
Amitai Eshel
So if we sit all the way, all, all the time in our office or, or we, we travel a lot or whatever that is. If, if we were, if we run in, in Manhattan, right. Wherever that is, we are getting way bombarded with heavy metals. We're getting bombarded with pollution, different WI fi signals, your phone, you're talking on your phone, you're frying your skin, et cetera, et cetera, et cetera. That is why when we designed BioShield, we went significantly further than just creating a product that protects you from the sun. So guess what? It also has lycochrome six that's magical antioxidant that also is a. And anti nitrogen free radicals and carbon based free radicals. It also has a botanical complex that we have that is also antioxidant oxidating as well, but also is a longevity botanical complex. And it also has a really, really, really cool peptide that is called ectoin. And ectoin is derived from these little bacteria that are called extremophiles. And if anyone has gone to Yellowstone and saw those pools of water with different, with almost like rainbow colors kind of emanating from them, These are extremophiles. They live in extreme climates. And what we know about them is that they have this peptide on their cellular membrane on the outside of their cells that repairs their cell protective layer extremely rapidly, faster than the heat or salt or whatever that is damages it. And that's why they can live on those environments. They're also called space teddy bears because of that, by the way. Because they allegedly can survive in space. I don't think they can, but that's what they say anyway, so, so this.
Dr. Stephanie Gray
Protects, I mean this is your main protector for EMFs, UV light, you know, pollution, whatnot. And it's a mineral based sunscreen that doesn't cause the white funky residue on your skin. Yes.
Amitai Eshel
So most sunscreens that you know of are going to get and accumulate in your brain. Okay. And this is from studies they can see 10 years, 10 years later. They can see chemical sunscreens and nano sized zinc oxide accumulated in the brain. And what we want to avoid are products that especially sunscreens, chemicals that can get into your bloodstream basically and get accumulated in the brain. So what we do is we have a special type of zinc oxide that's not nano. It doesn't, it doesn't get into your body, but it doesn't leave the white cast because it is a smaller diameter than a normal zinc oxide. It's not nano. It can't absorb, but it's smaller, a little bit. But we also use iron oxide. We use these pigment that is, that is not makeup. Men can use it too. I use it, but this pigment makes it. So it blends with every skin color, whether you're Fitzpatrick 1, which means extremely white, or Fitzpatrick 6, which is the other end of the spectrum. So anyone can use this product without leaving a white residue, even though it's 100% mineral. And by the way, when, when most products say mineral sunscreen, it can be 1% mineral and it can say mineral sunscreen. So this is 100% mineral.
Dr. Stephanie Gray
All right. What about tackling acne? I know many of my, I would say that the women in my major patient population are kind of past that demographic, but a lot of times they're asking for their daughters or whatnot. You know, what is the best product you have safe product for acne? Tackling acne.
Amitai Eshel
Yeah. So normally the products that we're going to use for acne actually kill the entire skin flora and they're going to create basically a wild wild west there afterwards. That's why, that's why there is such a, you know, high rebound rate and even worse. So what we do is we really try to nurture a good skin flora and, and make sure that we, we nurse the skin back into health. So a few ways to do it. A product that we didn't talk about is our Bio C PEPT spray, which is a spray that also can be used as a toner if people want to, but also something that you can use during the day. It does have peptides and vitamin C that protects you from blue light, etc. But also it improves skin flora. So that's number one, number two, and probably the hero as far as that. Remember, really what changes our systems are the serums, right? So the serum that I would highly recommend for people that have acne, whether adults or children or adolescents, it would be Green Tea Phyto serum. So Green tea Phyto serum was born to begin with, was created to improve red light therapy because it improves red light therapy by 200 but it also antimicrobial, antifungal and anti inflammatory which is big acne.
Dr. Stephanie Gray
Right, because acne inflammatory.
Amitai Eshel
Right, exactly. So when we see acne we are not seeing P. Acne bacteria, which is the bacteria that causes acne. What we are seeing the inflammation that is caused from that. So this bacteria builds around your poor hair follicle, whatever that is, blocks the ability for secretions to come out inflammation, et cetera. So we want to eliminate that bacteria, but we also want to eliminate inflammation. What we also want to do is to allow the skin or to improve how the skin releases dead skin. Because that's part of the issue. That's why people get acting when they're stressed. The cortisol makes it that you release a lot of dead skin but you release it in a way we're going to save on information here on time but you don't really release it. You just have it released from the top of your skin but it accumulates, it doesn't get left slept off very well. So we, we definitely want to improve how your skin eliminate or removes dead skin. So again we can go to NIA Polish and we can go to Bio Retinol and these two products are not going to kill the bacteria specifically but they're going to unclog the pores, they're going to again release the dead skin. So these are all important alongside using the Care moisturizer. If you have children under 25 and they, they need a moisturizer but they don't have the problem with nad. Right. They have their, their reservoir. Yeah, yeah. So we can use Care Boost which is a lighter moisturizer that doesn't have nad. It has all the other the peptides, the resveratrol, everything else, but no nad.
Dr. Stephanie Gray
Perfect. Want to ask you about two more products for our listeners. I mean I've even been using this. Can you mention the adaptogenic firming neck and chest product and then I also want to talk about the lip plumper quickly.
Amitai Eshel
Yeah, so this is actually a concept product. We, we source a few ingredients there that no one makes. So we kind of need to make them on our own. And that normally is a very big endeavor. We obviously do it with NAD precursors, etc. But every time you take this upon yourself it's almost like creating a whole new company. So this is really, really a concept product. And, and what we did is we created a product that is a kitchen sink approach for skin, for neck and chest skin rejuvenation. So it does have a very potent type of vitamin C. Again, not ascorbic acid, which is negative. It's not good. It also has peptides that eliminates something that's called glycation. So glycation is when sugar molecules attach to proteins. NAD is very good at countering that. But since this neck and chest product doesn't have NAD because it really is not good at absorbing NAD precursors, we needed to be very creative and find a different way to eliminate glycation. And we do it through lhibin and colhibin, which are two peptides that are really cool. They improve collagen production, et cetera, but they also eliminate glycation. And also we have there another peptide that's very good for collagen production and a xylitol derivative that improves the ability of your skin to create hydration or to hydrate itself, which is really cool. We use something similar in a product that we didn't talk about, which is the adaptogenic ha firming boost, which is the serum that someone that wants to improve the ability for their, their facial skin to hydrate itself to hold on to moisture. We also use a different patent there that's called Aqua Cell, that does something very similar that in 11 days doubles the ability of your skin to hold on to moisture.
Dr. Stephanie Gray
So that's hydrating product, what you just mentioned.
Amitai Eshel
I call it like a hydrating hydration gym. Some people have a problem that their, their skin barrier is impaired and they lose a lot of water. So that's going to be bio barrier. A lot of the times we're going to start this as a precautionary, but they're non mutually exclusive. Right. We can use both. So the adaptogenic ha firming boost would be a treatment for skin that is dry, that we want to improve its hydration.
Dr. Stephanie Gray
Okay, wonderful. Adaptogloss. Yes. I should have put it on before this interview.
Amitai Eshel
My perhaps it's a really cool product because normally it is a, a lipstick or whatever you want to call that.
Dr. Stephanie Gray
Lip gloss.
Amitai Eshel
Lip gloss. Lip gloss, yeah. But what's really, really cool about it is that it uses normally a lip plumper, uses caustic agents. It uses agents that sensitize the skin and then the skin becomes inflamed and puffs up. What's the problem with that? The problem is that an average American that uses lipstick swallows around four pounds of lipstick a year. Fun, but gross. Yes, but. So we definitely want to know what, what's in our, our lip gloss or lipstick. Right. So instead of having calcic agents which you would swallow and they Will damage your esophagus and, and going to cause irritation. We use a type of vitamin B3. We mentioned that, that niacin makes you flush. Right. There's actually a type of vitamins B3 that we use there that is even more flushing.
Dr. Stephanie Gray
Is that why you kind of feel, I mean, I've used it that way. You kind of feel the tingling sort of.
Amitai Eshel
Yeah, yeah.
Dr. Stephanie Gray
Okay.
Amitai Eshel
Yeah. So that is what plumps your lips a little bit.
Dr. Stephanie Gray
Not a lot, but safer, healthier way too.
Amitai Eshel
Exactly. And it turns into nad.
Dr. Stephanie Gray
Awesome.
Amitai Eshel
Yes. And we also have peptides there to make sure that, that there's less cracking and chap. Chapping and to, to make sure that there's no like little lines on your lips. Don't use it on the, on the sleep outside of your lip line because just. Yeah, yeah.
Dr. Stephanie Gray
Probably burn. Yes. Yeah, I know what listeners are thinking. Okay, so tell me the order. And this is the question my staff had also. Can you kind of go through, I want to personally ask you what you use on a daily basis, like what products you're using. Kind of start to finish in the morning, start to finish at night. Just so patients kind of know. Again, that order which we already identified a little bit of that being the sunscreen is the last thing in the morning, the mask is the last thing at night. That. Can you kind of break that down for us?
Amitai Eshel
Yes. So I'm going to tell you what I use and why I use it and you can take off whatever you would not be using. Right. So I obviously wash my face with the adaptogenic ha firming adaptogenic cleanser. Excuse me, Leave it on the skin for 10 seconds to 2 minutes. Wash it off. If you shave, shave. If you want to do facial cupping or whatever, you could do that as well. Or wash out, wash it off and dry my face with a towel and spray a few sprays of the bio C peptide spray immediately. So if I, if I feel I need more hydration. Normally I don't, but if I do, I will immediately apply the adaptogenic ha Fermi boost. Normally I don't. What I do normally is I use in the morning the bio barrier which, which again repairs my skin barrier. And then I use pro care. A lot of the times I'm lazy and I'm going to mix them both in my hand and apply them on my face together.
Dr. Stephanie Gray
So those are the serums, yeah.
Amitai Eshel
Yep, yep, exactly. So the middle point is our serums. What are we, what are we asking the skin to do? Then I apply my care moisturizer Excuse me. First at my eye care and I apply my care moisturizer also over my eye care for added hydration. In the morning, I let it absorb for a couple minutes, apply my. A couple pumps of the bioshield, which is our spf, and go about my day. At night, I'll wash my face.
Dr. Stephanie Gray
Wait, actually, let's pause. You. What about during the day? Do you use that peptide spray during the day?
Amitai Eshel
Yeah. So if I'm in front of the computer a lot or I'm somewhere that I am exposed to a lot of UV light or. Excuse me, or blue light, I'll apply it during the day. A lot of times when I'm outside, I. I don't take it with me. Now we have a travel size, so I do.
Dr. Stephanie Gray
I was gonna ask you about that. Yeah, yeah.
Amitai Eshel
So now, now I do take it with me because I have a travel size and, and especially if I do something that, that I exert a lot of energy, I just pump it and, and I get some energy back from, from that. Sure. As far as the night, I'll wash my face again, I'll shave again. No, I'm kidding. I wash my face, I apply the Bio C peptide spray. And what I do, I don't actually use Bio barrier or Procure. I use bioretinol most nights.
Dr. Stephanie Gray
Okay.
Amitai Eshel
As a person that has pretty thick and resilient skin. If I am not using the bio barrier, the bioretinol, I'll again do the combination of Bio barrier and Procare, apply my eye care, Apply care moisturizer. And instead of the spf, which I put in the morning, now I'll apply the hyperbaric mask and I'll go to sleep with it once or twice a week. I do I in the shower, I take a longer shower, I wash my face in the shower and I massage my skin with Nia polish very gently a couple times a week. Like a facial at home. If you would leave it on for 10 minutes, I wash it off and wash it off very easily. And then I'll do my entire routine. Normally it happens in the evening, but it can be in any time of day.
Dr. Stephanie Gray
So it really sounds like the regimen doesn't really differ between men and women. I mean, they all can use many of these products.
Amitai Eshel
The only where you will see a difference is when we talk about a protocol which we're building now, which is a cycle syncing protocol, which obviously in your practice it's significant since you talk a lot about hormones. So. So obviously every, every week of the month, or every phase because it's not necessarily a week. Every phase of the menstrual cycle, a woman has a different hormonal makeup that expresses itself in the skin also differently. So in one phase of the cycle you will be drier and you will need the adaptogenic ha firming boost. Another one, you'll be oilier and you'll be actually having a problem releasing dead skin. You'll be more again, you'll be prone to acne. So we can use again, bioretinol, we can use pro care. So that's a protocol we're going to come out with soon that would show you how to cycle the serums specifically in between and match serums to your menstrual cycle. And we have Dr. Mindy Pelz that's going to talk about it and Dr. Amy Horneman obviously. So, yeah, very cool.
Dr. Stephanie Gray
Exciting. Okay, this is great and I'm sure listeners want to hear more. So what's the best way listeners can educate themselves on your products? Tell us where they can find you, your website, all that jazz.
Amitai Eshel
Okay. So first and foremost, I highly recommend listening to our podcast that really dives super, super, super deep into many of the aspects that we talked about today, but also things that are not necessary about our products that can improve skin health. It's called Biohacking Beauty. You can find it on any where, wherever you consume your podcasts. Our Instagram page is extremely informative, especially by the way, if you're interested in cycle syncing and skincare. We do post about it once in a while. So you can definitely head out there. Head there it is. Young_goose_skincare. And obviously our website is www. Younggoose. It's one word, there's two GS there. Young goose.com and you know, for the, for your listeners, we actually have a special promo code that they get 10% off their first order, which is Dr. Gray, just D R Gray, one word, all caps and they'll get 10% off. And yeah, I highly recommend taking a very, very, very short quiz that's on the website that instead of listening to me babble for a long time, if you got tired, you can just go to that quiz, basically identify what you want to treat and et cetera, and you'll get a recommendation to one of our systems. You can go directly to the systems as well and choose the system that's right for you.
Dr. Stephanie Gray
Wonderful. Thank you so much. I will post obviously all those links and then that code. Capital Dr. Gray in the show notes for the 10% off, I'll have to ask one more question, but actually I'm going to turn that into two because I'm always very curious, like, where did the name Young Goose come from?
Amitai Eshel
We had to think of our feet, on our feet when we launched the company because the name that we chose originally, we found out there is a supplement company with that name. So we actually own the trademark for the word hormesis for skincare, but we tried to trademark it also for supplements just in case we ever did it. And we found out there's another company when we said, you know what, let's just change the name. We. When we were researching sirtuin activation, there were geese outside our lab that seemed to not grow old. So it was about five year research. And they seem to. They reach sexuality. Yeah, they reach sexual maturity in like two years. They look the same until they die, basically. So they were our mascot for like six years. They look the same. So this is this. We thought our field was like, we like the geese out there, let's just call it Young Goose. And it stuck.
Dr. Stephanie Gray
Some comedy there. Yeah, love it. Okay, last question. Finally. Thank you for your time today. What would your hop longevity tip be?
Amitai Eshel
I would say temperature. Temperature is my top longevity tip. We talked a lot about molecules today, but our bodies, if you remember, when we talked about nad, we said we actually didn't talk about it a lot. But we can take IVs, we can take supplements, we can do this, we can do that. Our body isn't very good at using molecules throughout systems in the body. You know, we can give examples on how adrenaline in the brain and in our body is completely different. We can talk about melatonin in our gut and in our brain. We can talk about nitric oxide inside your mitochondria. It kills the mitochondria outside of the mitochondria. We need it to dilate blood vessels, et cetera. So our body is not using the same molecule in a lot of different. Even oxytocin, which we all think of the love hormones.
Dr. Stephanie Gray
Connection hormone.
Amitai Eshel
Yeah, connection hormone is really a stress hormone in a lot of different ways. So our body is not very good at using molecules to communicate to the whole body. And a lot of the times what we want to do in health is holistically address health. Right. And temperature is our body's way to communicate to the whole system at once. So if we can modulate our temperature, we can go work out, we can be in a sauna, we can go and do an ice bath.
Dr. Stephanie Gray
Yeah.
Amitai Eshel
We definitely want to think improving our sleep, sleeping in a little bit cooler temperature than what we're used to. We really want to think of how we use temperature as a strategy for health and long termesis.
Dr. Stephanie Gray
Back to kind of what you were saying, too.
Amitai Eshel
Hormesis.
Dr. Stephanie Gray
Yeah, yeah, yeah. No one's ever said that. Unique answer. Thank you. So thank you today for coming on the show and just sharing with us how we can slow our skin aging, repair damage, showing how important nad is. You're a gem of a human. Very easy to listen to. So I'm excited to see your company continue to explode. Congratulations, and thank you very much on the show.
Amitai Eshel
It was my pleasure.
Biohacking Beauty: The Anti-Aging Skincare Podcast
Episode Summary: Stephanie Gray: Your Skin and Hormones Are Talking—Are You Listening?
Release Date: December 25, 2024
Host/Guest: Amitai Eshel (Young Goose CEO) & Dr. Stephanie Gray
In this special episode of Biohacking Beauty, Amitai Eshel, the CEO and co-founder of Young Goose, joins Dr. Stephanie Gray to discuss the intricate relationship between skin health, biohacking, and longevity. The conversation delves into how skin serves as a critical indicator of overall health and explores innovative strategies to achieve youthful, resilient skin.
[02:00] Dr. Stephanie Gray:
"Amitai has held executive roles in the health, wellness, and beauty industry for over a decade... He embodies his passions for performance optimization and skin health with products that boost the functions of natural rejuvenation processes in the body."
Amitai Eshel shares his journey from serving in the Israeli special forces to founding Young Goose. His military background instilled a passion for optimizing physical performance and wellness, which later transitioned into the skincare industry through biohacking principles.
[09:30] Amitai Eshel:
"Skin becomes more of a shield to protect our body from the environment rather than an organ that communicates vitality and youthfulness."
Amitai emphasizes that as we age, especially post-menopause, the skin shifts from being a signifier of vitality to primarily serving as a protective barrier. This transformation underscores the importance of maintaining skin health not just for appearance but for overall well-being.
Intrinsic vs. Extrinsic Aging
[15:29] Amitai Eshel:
"Around 20% of skin aging is intrinsic, stemming from internal factors, while 80% is extrinsic, influenced by environmental factors such as pollution, toxins, and UV exposure."
Amitai breaks down skin aging into intrinsic (genetic and internal) and extrinsic (environmental) factors, highlighting that the majority of skin aging in Western societies is driven by external elements.
Prevention First
[15:29] Amitai Eshel:
"Prevention is crucial. Protecting our skin from environmental aggressors using natural sunblocks, peptides, and antioxidants can significantly slow down the aging process."
Boosting NAD Levels
NAD (Nicotinamide Adenine Dinucleotide) plays a pivotal role in cellular repair and energy production. Amitai explains the challenges of delivering NAD directly to the skin and the alternative strategies Young Goose employs to boost NAD levels in skin cells.
[18:13] Amitai Eshel:
"NAD is the fuel for over 600 repair processes, including DNA integrity. As we age, NAD levels halve by age 60, leading to accumulated cellular damage and aging."
Amitai delves into the significance of NAD, detailing how its depletion contributes to the aging process by impairing the skin's ability to repair itself.
a. Care Moisturizer and Eye Care
[21:25] Amitai Eshel:
"Our Care moisturizer and Eye Care products are foundational for everyone, providing NAD precursors and peptides to fuel repair and maintain skin elasticity."
These products are enriched with NAD precursors like NR and NMN, enhancing the skin's repair mechanisms and boosting overall skin health.
b. Procare Serum
[24:00] Amitai Eshel:
"Procare Serum acts as a signal for anti-aging, reactivating 14 genes involved in collagen production, elastin, and hyaluronic acid synthesis."
Procare Serum targets genetic pathways to stimulate collagen and elastin production, addressing wrinkles, sunspots, and overall skin resilience.
c. Bioretinol
[37:51] Amitai Eshel:
"Bioretinol stimulates repair quickly by interacting with the MTOR pathway, enhancing collagen production without the common side effects of traditional retinols."
Bioretinol offers the benefits of retinol for wrinkle reduction and skin renewal while minimizing irritation through advanced formulation techniques.
d. Adaptogenic Cleanser
[25:00] Amitai Eshel:
"Our Adaptogenic Cleanser not only serves as a gentle cleanser but also as a shaving lubricant and preparation for facial treatments, containing peptides and apigenin to eliminate CD38 enzymes that deplete NAD."
This multifunctional cleanser supports skin barrier health and enhances the efficacy of subsequent skincare products.
e. Hyperbaric Mask
[44:34] Amitai Eshel:
"The Hyperbaric Mask mimics the effects of hyperbaric oxygen therapy, stimulating fibroblasts, detoxifying the skin, and activating longevity pathways like sirtuins and AMPK for enhanced skin rejuvenation."
Used overnight, the Hyperbaric Mask boosts cellular energy and repair, working synergistically with other products to maximize anti-aging benefits.
f. Bio Shield Sunscreen
[50:24] Amitai Eshel:
"Bio Shield goes beyond standard sun protection by also shielding against blue light, pollution, and EMF exposure, using non-nano zinc oxide and iron oxide to provide broad-spectrum protection without leaving a white residue."
This advanced sunscreen protects against multiple environmental stressors while maintaining a natural skin appearance.
g. Other Products
a. Wrinkles
[37:51] Amitai Eshel:
"Wrinkles result from collagen depletion. Our approach stimulates collagen production and repairs existing wrinkles through NAD support and retinol formulations."
b. Hyperpigmentation
[42:41] Amitai Eshel:
"Improving epigenetics and supporting melanocyte function with NAD-boosting products like Procare and Bioretinol effectively addresses hyperpigmentation issues such as melasma."
c. Acne
[54:47] Amitai Eshel:
"Instead of eliminating skin flora, our products nurture a healthy microbiome. The Green Tea Phyto Serum offers antimicrobial and anti-inflammatory benefits without disrupting the skin's natural balance."
Amitai outlines a comprehensive skincare routine integrating Young Goose's products:
Morning:
Evening:
[62:56] Amitai Eshel:
"I use our Adaptogenic Cleanser, Bio C Peptide Spray, Care Moisturizer, Procare Serum, and Bio Shield Sunscreen in the morning. At night, I alternate between Procare Serum and Bioretinol, incorporating the Hyperbaric Mask a few times a week for optimal results."
Advanced Antioxidants:
[29:14] Amitai Eshel:
"Lipochromin 6 in our products is 20 times stronger than vitamin C, offering a broader spectrum of free radical protection without sensitizing the skin."
Non-Nano Mineral Sunscreen:
[53:05] Amitai Eshel:
"Our Bio Shield uses a specialized zinc oxide formulation that provides effective protection without the white cast, suitable for all skin tones."
[71:00] Amitai Eshel:
"Temperature modulation is a top longevity strategy. Practices like regular exercise, sauna use, and ice baths can holistically enhance health by leveraging the body's natural hormesis responses."
Amitai concludes by emphasizing the importance of holistic approaches to health and longevity, advocating for strategies that the body can naturally and efficiently utilize.
On Skin as a Communication Organ:
[13:09] Amitai Eshel:
"The skin brain axis... communicates directly with the HPA axis, affecting stress responses and overall aging."
On NAD's Critical Role:
[18:13] Amitai Eshel:
"NAD is essential for over 600 repair processes. Without it, we accumulate damage leading to aging and disease."
On Vitamin C Alternatives:
[29:25] Amitai Eshel:
"Lipochromin 6 is not only strong but also a broad-spectrum antioxidant, eliminating both oxygen-based and nitrogen/carbon-based free radicals."
On Wrinkle Treatment Philosophy:
[37:51] Amitai Eshel:
"We're not just sweeping wrinkles under the carpet with fillers; we're correcting the underlying skin aging process."
This episode of Biohacking Beauty offers an in-depth exploration of the science behind skin aging and the innovative solutions provided by Young Goose. Amitai Eshel and Dr. Stephanie Gray provide valuable insights into how biohacking principles can be leveraged to achieve youthful, resilient skin through a combination of advanced skincare products and holistic health strategies.
For listeners eager to delve deeper into skin health and longevity, visiting Young Goose's website and following their podcast can offer additional resources and personalized skincare recommendations.