Transcript
Carl Zimmer (0:00)
Chasing Life is supported by the World as yous'll Know It, a podcast about the forces shaping the future. In this season, host and science journalist Carl Zimmer speaks to some of the most respected scientists in the field of aging research about the massive changes in human longevity and what comes next. Is our lifespan set or will a breakthrough add decades to our lives? Can older brains be rewired to function like younger ones? Which so called biohacks actually work? The world as you'll know it is available now. After zoomies at the dog park, it's time for Drive up at Target. In goes a big bag of kibble and one squeaky chicken toy for the good boy.
Kira Dehring (0:39)
Drive up.
Carl Zimmer (0:40)
That's ready when you are. Only in the Target app, just tap Target.
Dr. Sanjay Gupta (0:48)
Welcome to Paging Dr. Gupta. You know, I always really look forward to this time of the week. It's a chance for me to connect with you. I get to hear what's on your mind and I get to hopefully make some sense of the health questions you've been asking. But thank you so much for sending in all your questions. It really means a lot and I really do love hearing from you. Many of you apparently have been following the news because you saw that music legend Billy Joel recently canceled part of his tour after being diagnosed with a condition called normal pressure hydrocephalus, or nph. Now, hydrocephalus is a condition people often associate with infants with babies. You might have heard it described as water on the brain. But the thing about hydrocephalus, it can also occur in adults, typically people over the age of 65. So I'll tell you, you know Billy Joel. First of all, I love Billy Joel. One of the first concerts I ever attended. I'm a huge fan. When I heard about his diagnosis, especially as a neurosurgeon, it really got my attention. And judging from all the questions you've been sending in, seems like it got your attention as well. So today we're taking a closer look at nph, Normal pressure hydrocephalus. Kira's back with us. Kira, who are we hearing from?
Kira Dehring (2:02)
Hey, Sanjay. So today we're starting off with a question from Robert in Wells Main and he wants to know what causes hydrocephalus.
Dr. Sanjay Gupta (2:11)
All right, Kira, thank you and Robert, thank you for that question. Couple things. First couple basics, cerebrospinal fluid. Fluid that is circulating around the cerebrum, the brain and the spine. So imagine your brain and your spinal cord and you got this fluid that is constantly bathing it. That's the cerebral Spinal fluid. And we are continuously making this cerebral spinal fluid, or csf. It bathes the brain and the spinal cord, and then it gets reabsorbed into the bloodstream. Hydrocephalus is basically an abnormal buildup of that fluid. So there's these normal fluid filled spaces in the brain called ventricles. When you get a CT scan or some sort of brain imaging, you see what normal ventricle size looks like. And then you see hydrocephalus, where those normal ventricles look plump, look swollen, look filled with fluid. The type that Billy Joel has is called normal pressure hydrocephalus. And that's in large part because the fluid has built up slowly over time. And as a result, the fluid pressure inside the head is normal or close to normal. It's not elevated. Why does it happen? Well, sometimes we just don't know. Sometimes it's because the surrounding brain shrinks a bit and this fluid is sort of filling in that space. Sometimes it's because there is old head trauma, infection, tumors, perhaps a complication from surgery. But again, a lot of times we don't know. We do know that it can cause specific symptoms. In fact, classic, what we call triad of symptoms. Three symptoms, which are difficulty with walking, difficulty with cognition, and difficulty with bladder control. And these are some of the symptoms that Billy Joel has. So he has this condition, normal pressure hydrocephalus. He has some of the associated symptoms. And I'm sure right now they're probably having conversations with their doctors about what to do, how to best treat this. Now, one thing I will tell you is that normal pressure hydrocephalus is not a common condition, but it's a mimic of other conditions. Someone comes into the office with cognition problems. A lot of times you may think, well, this is dementia. You get a brain scan and you find in fact that the patient has normal pressure hydrocephalus, potentially treatable. Sometimes patients come in with questionable Parkinson's disease, they get a brain scan, and they're found to have normal pressure hydrocephalus, potentially treatable. You can see the pattern here. So again, not common, but potentially a treatable condition that mimics other existing conditions. Now, coming up, one of you asked about something that your mom is going through a spinal tap for. Normal pressure hydrocephalus. Could it actually help? What else could possibly help? We're going to talk it through right after the break.
