
Hosted by Commune · EN

What happens to your gut when estrogen declines? In this episode, Jeff sits down with Cynthia Thurlow, nurse practitioner and author of The Menopause Gut, to explore the overlooked connection between hormones and digestive health. How declining estradiol impacts the microbiome and increases inflammation What is the estrobolome and estrogen processing in the gut Why 80% of autoimmune conditions affect women Sleep, stress, and their cascading effects on gut health Practical protocols for nutrition, movement, and hormone optimization This episode is for women navigating perimenopause and menopause, anyone curious about the gut-hormone connection, and those seeking science-backed strategies for midlife health. Stripes: Visit stripesbeauty.com and use the code COMMUNE20 for 20% off our entire product line. Stemregen: Get 20% off your first order at stemregen.co/commune with the code COMMUNEPOD Vivobarefoot: Try Vivobarefoot risk-free with a 100-day return guarantee, and get 25% off your order at vivobarefoot.com/commune. LMNT: Get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase at drinklmnt.com/commune.

NAD+ has become the longevity industry's favorite molecule, sold as as a supplement and as a four-hour IV that promises sharper thinking, more energy, and slower aging. But a new 2026 paper complicates the very story it was built on. In this episode, Jeff breaks down what NAD+ actually is, what the human trials really show, and why the gap between a $40 oral supplement and a $1,200 IV drip matters more than the marketing admits. You’ll learn about: What NAD+ does in the body and why it got tied to aging The new research questioning whether NAD+ truly declines with age Oral NR and NMN versus IV infusions, and what the evidence supports The risks rarely mentioned, including the cancer question Why the saline, B vitamins, and forced rest may explain how good people feel This episode is for anyone weighing NAD+, longevity supplements, or an IV drip, and who wants to tell real science from wellness hype first. This episode was made possible by: LMNT: Get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase at drinklmnt.com/commune. Stemregen: Get 20% off your first order at stemregen.co/commune with the code COMMUNEPOD Vivobarefoot: Try Vivobarefoot risk-free with a 100-day return guarantee, and get 15% off your order at vivobarefoot.com/commune. Stripes: Visit stripesbeauty.com and use the code COMMUNE20 for 20% off our entire product line. Sunlighten: Visit sunlighten.com/commune Up to 2,100 off saunas and $50 off Red Light Products with code “COMMUNE”

How do you regulate your nervous system in a world built to hijack it? In this episode, Jeff sits down with Sam Harris, neuroscientist, author, and creator of the Waking Up meditation app, for part two of a two-part conversation. After diagnosing the political chaos in part one, they pivot to the practice of meeting it with clarity, exploring mindfulness, non-duality, and what's prior to thought. They discuss: Why almost no one can hold attention for 30 seconds The real root of psychological suffering Dualistic vs. non-dualistic meditation practice Psychedelics and meditation compared The social construction of the self, from childhood to Sartre The hard problem of consciousness and the mystery of awareness If you want to learn Sam’s approach to staying engaged with the world without losing your mind to it, go to https://onecommune.com/sam to get 30 days of his Waking Up app for free. This episode was made possible by: Vivobarefoot: Try Vivobarefoot risk-free with a 100-day return guarantee, and get 15% off your order at vivobarefoot.com/commune. Stemregen: Get 20% off your first order at stemregen.co/commune with the code COMMUNEPOD LMNT: Get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase at drinklmnt.com/commune. Stripes: Visit stripesbeauty.com and use the code COMMUNE20 for 20% off our entire product line. Sunlighten: Visit sunlighten.com/commune Up to 2,100 off saunas and $50 off Red Light Products with code “COMMUNE”

Liver detoxes are a $10 billion industry. The liver is also the most regenerative organ in the body, running its own continuous cleanse without your help. In this episode of The Commune Podcast, Jeff Krasno walks through what's actually known about liver health, from juice cleanses to gallbladder flushes to the supplements lining every wellness aisle. How the liver actually metabolizes and clears toxins Why the green "stones" in popular flushes are just solidified olive oil Fatty liver disease, fructose, and the irony of fruit-heavy cleanses The evidence for coffee, cruciferous vegetables, exercise, and fiber Which supplements have real research: milk thistle, berberine, NAC, sulforaphane This episode is for anyone considering a cleanse who wants to know what works, what doesn't, and what's worth their money. This episode was made possible by: Sunlighten: Visit sunlighten.com/commune Up to 2,100 off saunas and $50 off Red Light Products with code “COMMUNE” Beyond Biohacking: Save $400 on any ticket with code COMMUNE400 at beyondconference.com. Vivobarefoot: Try Vivobarefoot risk-free with a 100-day return guarantee, and get 15% off your order at vivobarefoot.com/commune. Stripes: Visit stripesbeauty.com and use the code COMMUNE20 for 20% off our entire product line. LMNT: Get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase at drinklmnt.com/commune.

Sam Harris has two brains. One is making sense of the political chaos. The other is waking up from it. In this episode, Jeff sits down with Sam Harris, neuroscientist, author, and host of the Making Sense podcast, for part one of a two-part conversation on surviving the modern world with your sanity intact. They unpack the outrage machine, political tribalism, and what it actually takes to stay clear-headed inside the noise. They discuss: Why Sam finally quit Twitter after 12 years, and what changed How the attention economy fuels hyper-partisanship and authoritarianism The moral panic around race, and how it radicalized the center Immigration policy, deportation, and the abandonment of Afghan allies Free speech, Orbán's defeat, and the future of liberal democracy If you want to learn Sam’s approach to staying engaged with the world without losing your mind to it, go to https://onecommune.com/sam to get 30 days of his Waking Up app for free. This episode was made possible by: Vivobarefoot: Try Vivobarefoot risk-free with a 100-day return guarantee, and get 15% off your order at vivobarefoot.com/commune. Sunlighten: Visit sunlighten.com/commune Up to 2,100 off saunas and $50 off Red Light Products with code “COMMUNE” Beyond Biohacking: Save $400 on any ticket with code COMMUNE400 at beyondconference.com. LMNT: Get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase at drinklmnt.com/commune. Stripes: Visit stripesbeauty.com and use the code COMMUNE20 for 20% off our entire product line.

Creatine is one of the most researched and most misunderstood compounds in the supplement aisle. In this episode, Jeff walks through what the evidence actually says about creatine for muscle, brain health, aging, and women's health, and where the legitimate cautions sit. Inside: How phosphocreatine fuels muscle and brain cells New 2024 and 2025 research on cognition and women's hormonal health Sarcopenia, emerging Alzheimer's trials, and aging well What to buy (creatine monohydrate, Creapure, NSF Certified) and what to skip Why bipolar history, kidney disease, and chronic NSAID use matter This episode is for anyone curious about creatine, women navigating perimenopause and menopause, and adults thinking ahead about strength and cognitive longevity. This episode was made possible by: Stemregen: Get 20% off your first order at stemregen.co/commune with the code COMMUNEPOD Sunlighten: Visit sunlighten.com/commune Up to 2,100 off saunas and $50 off Red Light Products with code “COMMUNE” Beyond Biohacking: Save $400 on any ticket with code COMMUNE400 at beyondconference.com. LMNT: Get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase at drinklmnt.com/commune. Stripes: Visit stripesbeauty.com and use the code COMMUNE20 for 20% off our entire product line.

Your diet, sleep, and exercise won't save you if your nervous system is chronically on fire. In this episode, Jeff talks with Elisha Goldstein — psychologist and author of Tiny Shifts — about emotional longevity: what it is, why it matters for aging, and how to start building it today. The overlooked link between emotional dysregulation and physical health The "overwhelm loop" and how to interrupt it in real time The Four Rs: a practical recovery framework for everyday stress Why recovery speed matters more than avoiding stress altogether This episode is for anyone who already knows what they should do — and wants to understand why they can't quite do it yet. This episode was made possible by: Stemregen: Get 20% off your first order at stemregen.co/commune with the code COMMUNEPOD Sunlighten: Visit sunlighten.com/commune Up to 2,100 off saunas and $50 off Red Light Products with code “COMMUNE” Beyond Biohacking: Save $400 on any ticket with code COMMUNE400 at beyondconference.com. LMNT: Get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase at drinklmnt.com/commune. Stripes: Visit stripesbeauty.com and use the code COMMUNE20 for 20% off our entire product line.

A single blood draw promises to screen for more than fifty cancers. A full-body MRI can capture you head to thigh in under an hour. But should you actually take one? In this episode, Jeff Krasno walks through the science, the marketing, and his own experience taking the Galleri test after his father's death from cancer. He compares Galleri to direct-to-consumer MRIs from Prenuvo and Ezra, and lays out what the evidence does and doesn't support. How Galleri and full-body MRI actually work What the recent NHS Galleri trial showed Lead time bias, overdiagnosis, and the diagnostic cascade Four honest questions to ask before getting screened Why lifestyle remains the biggest lever for cancer risk This episode is for anyone considering direct-to-consumer cancer screening, navigating a family cancer history, or trying to read between the lines of wellness marketing. This episode was made possible by: Beyond Biohacking: Save $400 on any ticket with code COMMUNE400 at beyondconference.com. LMNT: Get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase at drinklmnt.com/commune. Sunlighten: Visit sunlighten.com/commune Up to 2,100 off saunas and $50 off Red Light Products with code “COMMUNE” Vivobarefoot: Try Vivobarefoot risk-free with a 100-day return guarantee, and get 15% off your order at vivobarefoot.com/commune. Stripes: Visit stripesbeauty.com and use the code COMMUNE20 for 20% off our entire product line.

Most transformation fails because we're aiming at the wrong thing. We want change, but what we're actually chasing is presence. In this episode, Jeff sits down with Light Watkins, meditation teacher and author, to unpack the real mechanics of personal change: why it has to start with gratitude, why seven days beats 365, and how small, specific challenges compound into a different life. They explore: Why presence is the real goal behind every desire for change Gratitude 1.0 vs. 2.0 The tortoise approach to transformation vs. the crisis and Eat Pray Love models Seven-day challenges as a sustainable pathway to lasting habits This episode is for anyone who's tried to change and stalled… and wants a more honest, low-drama way forward. This episode was made possible by: Beyond Biohacking: Save $400 on any ticket with code COMMUNE400 at beyondconference.com. LMNT: Get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase at drinklmnt.com/commune. Sunlighten: Visit sunlighten.com/commune Up to 2,100 off saunas and $50 off Red Light Products with code “COMMUNE” Vivobarefoot: Try Vivobarefoot risk-free with a 100-day return guarantee, and get 15% off your order at vivobarefoot.com/commune. Stripes: Visit stripesbeauty.com and use the code COMMUNE20 for 20% off our entire product line.

You wake up feeling rested, check your Oura Ring, and suddenly you're tired. In this episode, Jeff Krasno examines whether sleep trackers like Oura, Whoop, and Apple Watch are genuinely improving our health or actually creating a new kind of sleep anxiety. He explores: What sleep trackers actually measure versus what they only model Orthosomnia and the rise of tracker-induced sleep anxiety Where Oura, Whoop, and Apple Watch are reliable, and where they aren't HIPAA gaps, FDA clearance, and what your data is worth Who benefits from wearing one, and who probably shouldn't This episode is for anyone wearing a sleep tracker, considering one, or wondering whether the score on their wrist is making them healthier or just more anxious. This episode was made possible by: Bon Charge: Get 15% off when you order at boncharge.com and use promo code COMMUNE Beyond Biohacking: Save $400 on any ticket with code COMMUNE400 at beyondconference.com. LMNT: Get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase at drinklmnt.com/commune. Sunlighten: Visit sunlighten.com/commune Up to 2,100 off saunas and $50 off Red Light Products with code “COMMUNE” Vivobarefoot: Try Vivobarefoot risk-free with a 100-day return guarantee, and get 15% off your order at vivobarefoot.com/commune.