There is a series of theological debates between Rabbi Yehoshua ben Hananya and the Roman emperor, which demonstrate the sublimity of God through man's inability to look directly at the sun or to sustain the natural armies that serve God. A similar discussion with the emperor's daughter, who scoffed at the providence of God in the world, leads to a punishment of leprosy being inflicted upon her, emphasizing the principle that God's presence is indirectly guiding the world.

Rav Yehuda defines the difference between the dimensions of an ox and a donkey that affect the laws of buying and selling. He also explains that the ox sacrificed by Adam possessed only a single horn on its forehead, and that its horns preceded its hooves in creation. This structural precedence supports the view of Rabbi Yehoshua ben Levi, according to which all works of creation were created in their full stature, their full understanding, and their full mature form. Rabbi Chanina bar Papa expounds that the Angel of the World praised the grasses when they applied a kal v'chomer argument and proactively emerged according to their specific kinds (without intermixing), as derived from Genesis 1:11–12.

Rabbi Shimon ben Pazi reconciles the scriptural contradiction regarding the creation of the luminaries, detailing the moon's claim that two kings cannot share a single crown, which prompted the divine decree for it to diminish itself. To appease the moon, God granted it dominion by both day and night, linked Israel's calendar to the moon's counting of days and years, and called righteous people "small" like the moon. However, the moon was not appeased by all of these attempts, and God then established a sin offering to be offered on Rosh Chodesh (the New Moon) - a male goat - as an atonement for God. Rav Asi reconciles a contradiction in Creation regarding the emergence of vegetation, explaining that the grass remained hidden at the opening of the ground until the prayer of Adam brought down rain and caused them to sprout, teaching that God desires the prayers of the righteous.

Rav Chanan bar Rava identifies the shesua as a unique creature possessing two backs and two spinal columns - as definitive proof that the Torah is from Heaven, as it is impossible to believe that Moshe knew of the existence of that creature.

Reish Lakish analyzes a series of seemingly redundant verses, emphasizing that they constitute the core essentials of the Torah itself. For example, the description of the displacement of nations in the land of the Philistines and the land of Moab via intermediary conquests was legally meant to permit the eventual conquest of the land without violating ancient oaths or divine decrees.