
Hosted by Dr. Gillian Lockitch · EN

THIS FLASHBACK FRIDAY EPISODE OF GROWING OLDER LIVING YOUNGER focuses on the effect of aging on brain functions, affecting many attributes of cognition, like memory and processing speed; and on the importance of recognizing the early warning signs of dementia for early treatment. Today's guest is neuropsychiatrist and creator of the SAGE test, Dr. Douglas Scharre. Dr. Scharre is board certified in neurology, behavioral neurology and neuropsychiatry with special interests in cognitive assessment, degenerative dementias and dementia-related behaviors. He joined The Ohio State University Wexner Medical Center faculty in the Department of Neurology in 1993. Dr. Scharre's publications cover a broad range within the area of cognitive neurology including dementia, Alzheimer's disease, Lewy body dementia, Parkinson's disease, Huntington's disease and much more. His research also covers neuropsychiatric aspects of disease, biomarkers, functional neuro-imaging and treatment of behavioral disturbances in dementia. Episode Timeline: 0:11 Intro to this episode 3:19 Aging and memory loss 6:33 Distinguishing between normal aging and dementia. 11:23 The SAGE Test (Self Administered Gerocognitive Examination) and its benefits 15:38 Why use the SAGE test? 19:36 Differentiation of forms of dementia 24:38 Lifestyle changes for healthy mind and healthy body 27:42 New biomarkers for Alzheimer's 32:17 The genetics of Alzheimer's 37:56 Best ways to challenge your brain Learn more about Dr. Scharre's work here: https://wexnermedical.osu.edu/neurological-institute/researchers/douglas-scharre-md Access the SAGE test to check yourself at home: https://wexnermedical.osu.edu/brain-spine-neuro/memory-disorders/sage Get to know Your Host: Dr. Gillian Lockitch website: https://www.askdrgill.com/ Facebook: https://www.facebook.com/gillian.lockitch/ LinkedIn: https://www.linkedin.com/in/gillianlockitch/ X: https://twitter.com/GilliansReviews To get your copy of Growing Older Living Younger: The Science of Aging Gracefully and The Art of Retiring Comfortably click here And if you have not already done so, I would love you to follow, rate and review the show.

What if the future of aging is no longer defined simply by lifespan, but by how long we can remain mentally sharp, physically active, emotionally connected, and fully engaged with life? In this thought-provoking episode, Dr. Gillian Lockitch speaks with documentary filmmaker, David Donnelly, director of the acclaimed documentary, Forever Young, about the rapidly evolving science of longevity and the questions for humanity, emerging alongside the science. Together, they explore the difference between lifespan and healthspan, the growing role of biomarkers, wearables, epigenetics, and lifestyle medicine, and the ethical and emotional implications of extending human life. Listeners will gain insight into the science driving the longevity revolution while reflecting on what it truly means to age well in a technology-driven world. David Donnelly is an award-winning documentary filmmaker and director. His work focuses on science, human performance, creativity, technology, and the evolving human experience. His first internationally distributed documentary, Maestro, explored musical mastery and Estonia's Singing Revolution through the life of conductor Paavo Järvi. He later directed documentaries including Nordic Pulse, Forte, and The Cost of Convenience, examining culture, technology, and human autonomy. In Forever Young, Donnelly spent three years documenting leading longevity scientists and exploring the biological, ethical, and philosophical dimensions of extending human healthspan and lifespan. His work bridges scientific complexity with accessible storytelling that invites audiences to reflect on the future of aging and humanity itself. Episode Timeline 00:00 – Welcome and introduction 02:35 – The longevity revolution and redefining healthy aging 03:58 – David Donnelly's journey from pre-med student to filmmaker 05:30 – The documentary Maestro and Estonia's Singing Revolution 08:37 – Why longevity science became the focus of Forever Young 10:59 – Dr. Lockitch's personal journey into epigenetics and healthspan 13:17 – Healthspan versus lifespan and the science-fiction future of aging 15:06 – The "Death Doula" concept and the death-positive movement 17:46 – Death meditation, grief, and facing mortality consciously 19:43 – Longevity science, biomarkers, and rethinking how we spend our lives 22:15 – Wearables, biological age testing, and tracking healthspan 26:28 – Hallmarks of aging and emerging biomarkers of longevity 29:01 – Ethical questions around lifespan extension and "escape velocity" 31:13 – Human trials targeting aging itself and the future of longevity medicine 33:27 – Epigenetics, lifestyle medicine, and personal responsibility for health 35:47 – Environment, socioeconomic factors, and the cultural barriers to longevity 37:00 – Digital dementia, screen addiction, and modern threats to brain health 38:40 – The powerful message: Your genes are not your destiny 41:12 – Where to watch Forever Young and connect with David Donnelly Connect with the work of David Donnelly Forever Young Film Official Website Forever Young Substack Watch the documentaries Forever Young and Maestro Call to Action Subscribe to Growing Older Living Younger on your favorite podcast platform and leave a review to help others discover the show. Join the Growing Older Living Younger Community at Growing Older Living Younger Community Connect with Dr. Gillian Lockitch at Ask Dr. Gill Official Website or email: askdrgill@gmail.com Download Guide to Nature's Colorful Antioxidants 2026: Nature's Colorful Antioxidants Guide

FLASHBACK FRIDAY: A recurring theme in this podcast is the importance of mindset in supporting consistency, when making the small changes in lifestyle and habits that can have a big positive impact on your health and vitality as you age. Your beliefs shape how you think, feel and act. And if you are to overcome life's challenges when they strike, you have to believe in your ability to do so.My guest today, Adena Sampson, is the founder of Outloud Productions & The Unbreakable Spirit movement, a breakthrough coach, and best-selling author of the book. The Road Back to Me: 9 Principles for Navigating Life's Unexpected Twists and Turns.As an accomplished singer-songwriter, guitarist, and producer, Adena has been emcee, narrator and presenter, for workshops and seminars, voiceovers and jingles, commercials and broadcasting. An entrepreneur at heart, Adena has an extensive background in event management, media, marketing and sales and has built and trained solid teams. In the network marketing industry, as a high-performance leader with an online technology company, ranking in the top 40 of 20,000, she was responsible for the growth and expansion of over 500 affiliates.We talk about the compelling story that led her to become an inspiring coach, teaching how to overcome challenges and turn them into victories. We discuss how getting Lyme disease, changed the direction of her life. Adena shares details the 3 top principles of the 9 she describes in her book. To discover how to Reset Your Aging Blueprint and create your own roadmap to living younger as you grow older, schedule a free 0ne on 0ne Call with me. by emailing gillian@askdrgill.com Learn more about Adena Sampson and the book: The Road Back to Me: 9 Principles for Navigating Life's Unexpected Twists and Turns.info@adenasampson.com www.AdenaSampson.com

Are the so-called "heart-healthy" vegetable oils in your kitchen truly supporting your health—or could they be contributing to inflammation and metabolic imbalance? In this episode of Growing Older Living Younger, Dr. Gillian Lockitch speaks with nutrition expert Cherie Calbom, MS, CN, about industrial seed oils such as canola, soybean, sunflower, and corn oil, and the growing concerns surrounding their role in oxidative stress, chronic inflammation, and healthy aging. Cherie explains how highly processed oils may affect metabolic health, brain function, and overall wellness, and shares practical guidance on choosing healthier fats and using nutrition strategies—including juicing—to support vitality and longevity. This conversation offers actionable insights for anyone who wants to reduce inflammation, make more informed food choices, and age with greater energy and resilience.Cherie Calbom, MS, CN, is a certified nutritionist, wellness educator, and bestselling author widely known as "The Juice Lady." She holds a Master of Science degree in nutrition and has written 36 books, including the classic Juicing for Life. Cherie has received two Lifetime Achievement Awards for her pioneering contributions to nutrition and wellness education. She has served on the Board of Regents at Bastyr University and has advised high-profile leaders, including George Foreman. Her latest book, The Truth About Seed Oils, challenges conventional dietary advice and offers practical strategies to reduce inflammation and support better health. Episode Timeline 00:00 – Introduction and episode overview Dr. Gillian introduces the controversy surrounding industrial seed oils and their potential role in inflammation and chronic disease. 03:13 – Cherie's healing journey Cherie shares how she overcame chronic fatigue syndrome and fibromyalgia through juicing and whole food nutrition. 07:53 – The first healing juice recipes The vegetable juices Cherie used to restore her health and why variety matters. 10:20 – The NAMA J2 juicer Cherie describes her favorite hands-free juicer and how it simplifies daily juicing. 11:50 – What are seed oils? A historical overview of vegetable oils and how they became mainstream. 16:48 – Why canola oil became so dominant The economic reasons manufacturers favor cheap industrial oils. 18:57 – The chemistry of oxidation and inflammation How polyunsaturated fats become unstable and generate harmful byproducts. 21:10 – The worst oils to avoid Soybean, canola, corn, sunflower, safflower, cottonseed, grapeseed, and rice bran oils. 22:43 – Healthy fats to use instead Olive oil, avocado oil, coconut oil, ghee, tallow, and sesame oil. 25:14 – Seed oils, weight gain, and brain health Why reducing industrial oils may support body composition and cognitive vitality. 29:13 – One simple change to start today Read labels, eliminate seed oils, and choose traditional fats. 30:09 – Final thoughts and favorite health maxim: "Nothing on earth tastes as good as good health." Connect with Cherie Calbom IG @juiceladycherie FB @thejuicelady YouTube: TheJuiceLadyCherie LinkedIn: Cherie-Calbom X @juiceladycherie Call to Action: Find Growing Older Living Younger: The Science of Aging Gracefully and the Art of Retiring Comfortably at www.gillianlockitch.com (North America) Subscribe to Growing Older Living Younger on your favorite podcast platform and leave a review to help others discover the show. Join the Growing Older Living Younger Community Connect with Dr. Gillian Lockitch at https://www.askdrgill.com/ or email: askdrgill@gmail.com Download Guide to Nature's Colorful Antioxidants. 2026

FLASHBACK FRIDAY FB 29 Dec 2021 Agnes de Mille, American dancer and choreographer expresses the power of dance: "To dance is to be out of yourself. Larger, more beautiful, more powerful. This is power, it is glory on earth and it is yours for the taking." Does dance also have the power to ward off dementia? Today's guest is Dr. Joe Verghese, Professor of Neurology at the Albert Einstein College of Medicine in New York. His research centers around the effects of aging and disease on gait and cognition in older adults, and whether cognitively stimulating activities such as dance, can reduce the risk of losing mobility, falling, developing dementia and general poor health. In an early study of the association of Leisure Activities and the Risk of Dementia in the Elderly, 3 of 6 cognitive activities included (reading, playing board games and playing musical instruments) were associated with a lower risk for dementia, but of the 9 listed physical activities, only dancing was associated with a lowered risk. We touch on current studies of physicality and cognitive training for those at risk for Alzheimer's. One recent pilot study into the impact of regular social dancing as an intervention in older adults at high risk for Alzheimer's disease had to be cut short during the pandemic with only half the expected participants completing the study. Another recent study is investigating whether computerized cognitive training could enhance mobility in older adults. There remains some controversy about cognitive training. It is clear that there is a 'near transfer' effect, improvement on testing because you're training on that same process on which you're testing them. And consistently, almost every study shows that there is a near transfer effect. The challenge is whether that translates into improvement of executive function for real life skills, ie, a 'far transfer effect.' For those of us looking to age youthfully, keeping active both physically and mentally, Dr Verghese suggests: "Pick a few leisure activities that you enjoy and then engage in them at least five days a week, but every day, if you can. It's good if you do it as part of a group, because then there's a group dynamic; when you get together in a group, there's peer support that you get. And also increasingly we are recognizing that socialization itself might have cognitive benefits. So people who socialize more tend to have better cognitive function. and seem to be at less risk of cognitive decline" To learn how you can decelerate your aging trajectory, stay vibrant and vigorous, or start your own online business in wellness and anti-aging, Contact Dr. Gillian Lockitch Email: askdrgill@gmail.comSchedule a complimentary Living Younger Discovery Call through the above email Order your copy of Growing Older Living Younger: The Science of Aging Gracefully and the Art of Retiring Comfortably at www.gillianlockitch.com (N. America only)

What if one of the most powerful anti-aging tools already exists within your body? This episode explores autophagy, the body's natural cellular renewal system, and how activating it can support healthy aging and longevity. Longevity expert Leslie Kenny shares her personal journey of reversing autoimmune disease and translating cutting-edge science into practical strategies. Listeners will discover how autophagy promoting spermidine, proper nutrition, and baseline lifestyle habits influence cellular repair, resilience, and biological aging. Leslie Kenny is the founder of Oxford Healthspan, a company focused on translating longevity science into practical health solutions. She is a longevity researcher with expertise in cellular aging, autophagy, and immune system modulation. Her career includes work in finance and policy before a personal medical crisis led her to transition into health science. She specializes in spermidine research and its role in activating autophagy and influencing the hallmarks of aging. She is co-founder of the Oxford Longevity Project, a nonprofit dedicated to education in healthy aging. Episode Timeline 00:00 – Welcome and introduction 02:00 – Reframing aging as a modifiable biological process 03:50 – Leslie Kenny's autoimmune diagnosis and turning point 10:50 – Limitations of modern healthcare and the need for prevention 14:50 – What autophagy is and why it matters for longevity 17:00 – Spermidine and its role in cellular renewal pathways 21:30 – Nutrition, mushrooms, and dietary sources of spermidine 24:30 – Hallmarks of aging and systemic cellular decline 31:00 – Development of Primadine and supplement formulation science 37:00 – Practical strategies: fasting, diet, and supplementation 41:30 – Key takeaways on influencing biological agin Connect with Leslie Kenny https://oxfordhealthspan.com Instagram: @lesliesnewprime @oxfordhealthspan @oxfordlongevityproject To try Primadine Spermidine Supplement:Code: GOLY15 Link: https://www.oxfordhealthspan.com/GOLY15 Please note that Dr. Lockitch retired from medical practice and does not diagnose, prescribe for or treat any medical conditions. Before ordering any product discussed in these podcasts, consult your health care practitioner. Connect with Dr. Gillian Lockitch at https://www.askdrgill.com/ or email: askdrgill@gmail.com Subscribe to Growing Older Living Younger on your favorite podcast platform and leave a review to help others discover the show. Join the Growing Older Living Younger Community at https://www.facebook.com/groups/growingolderlivingyoungercommunity Download Guide to Nature's Colorful Antioxidants 2026

Flashback Friday - Episode 32 dates from Dec 2021 but ageism is still a hot topic in 2026 "Too old at 72? Careful. Ageism is out. We'll have the law on you! (Melvyn Bragg)" Hubris? I avoid 'isms' but I open this conversation with an anecdote of the first overt instance of ageism that I personally encountered, just before recording this podcast. Today's guest explores the structural ways we tolerate and promote behaviors toward people based solely on their age and how cultural norms and prejudices unconsciously shape our treatment of others and expectations about our own aging. We talk about what ageism, ableism and successful aging means and how these concepts affect both societal attitudes but also our own perceptions of ourselves extending into every factet of life including technology. Learn more about Dr. Gendron's work at www.traceygendron.com Her book: Ageism Unmasked: Exploring Age Bias and How to End It. Dr. Gillian Lockitch To learn how you can decelerate your aging trajectory, stay vibrant and vigorous, or start your own online business in wellness and anti-aging, book a call with me by email at askdrgill@gmail.com Order your personal copy of Growing Older Living Younger, the Science of Aging Gracefully and the Art of Retiring Comfortably at www.gillianlockitch.com

What if aging is not only driven by what happens inside our cells, but also by factors circulating in our blood? In this thought-provoking episode, Dr. Gillian Lockitch talks with Brad Younggren to explore the emerging science behind therapeutic plasma exchange and its potential to influence inflammation, biological aging, and chronic disease. Drawing on human clinical trial data, including the Circulate Trial, he explains how removing pro-aging factors from plasma may impact biomarkers, biological age, and overall healthspan. This conversation offers a fascinating glimpse into the future of longevity medicine while reinforcing the importance of foundational lifestyle strategies for aging youthfully. Dr. Brad Younggren is the CEO and co-founder of Circulate Health, a company focused on advancing human healthspan through innovative therapies. He is a board-certified emergency physician and former U.S. Army combat physician, where he was awarded the Bronze Star and Combat Medical Badge. Dr. Younggren has held multiple leadership roles at the forefront of healthcare innovation, including President and Chief Medical Officer at 98.6, where he helped develop AI-powered primary care solutions. His career spans digital health, medical devices, and global healthcare delivery. Today, he leads research into therapeutic plasma exchange and its potential role in longevity science and chronic disease. Episode Timeline: 00:00 – Welcome and introduction 02:30 – Aging beyond the cell: circulating factors in the bloodstream and their role in inflammation and disease 05:00 – Dr. Younggren's journey from emergency medicine to healthcare innovation and longevity science 09:00 – The evolution of digital health and smartphone-based diagnostics 12:00 – What is therapeutic plasma exchange and how it has been used in medicine for decades 15:45 – The Circulate Trial explained: study design, treatment groups, and control methodology 18:30 – Measuring outcomes: biomarkers, cognitive testing, grip strength, and biological clocks 21:00 – Key findings: biological age reduction and changes in proteomic markers 24:30 – Translating complex science into practical biomarkers patients can track 26:30 – Applications beyond longevity: chronic disease, Alzheimer's research, and long COVID 30:30 – Microplastics and plasma exchange: emerging research and early findings 33:00 – Evaluating longevity therapies: why human data matters 35:30 – Foundational health habits versus advanced interventions 36:50 – Wrap-up and key takeaways Connect with Dr. Brad Younggren Circulate Health: https://www.circulate.health Circulate Trial publication (Aging Cell journal) Information on plasma exchange and ongoing research initiatives Call to Action: Find Growing Older Living Younger: The Science of Aging Gracefully and the Art of Retiring Comfortably (North America) or on Kindle Subscribe to Growing Older Living Younger on your favorite podcast platform and leave a review to help others discover the show. Join the Growing Older Living Younger Community Connect with Dr. Gillian Lockitch at https://www.askdrgill.com/ or email: askdrgill@gmail.com Download Guide to Nature's Colorful Antioxidants. 2026

FLASHBACK FRIDAY EPISODE 008 May 2021 'A man is not old until regrets take the place of dreams.' (John Barrymore) 'Miracles are objects and events in nature and in our lives, that cannot be fully explained or recreated' (Dr. Harley Rotbart) Dr. Harley Rotbart is the author of "No Regrets Living: 7 keys to a life of Wonder and Contentment", is an infectious disease specialist, Professor and Vice-Chair Emeritus of Paediatrics at the University of Colorado School of Medicine. Having over 175 medical and scientific publications, his career is deeply rooted in science. Yet his experiences as a physician at Children's Hospital Colorado, taught him to believe in miracles, and that there are things beyond our ability to know. His 7 Keys to a life of content encompass belief in a power greater than ourselves, discovering the messiah within each of us, healing evil whether within ourselves or in the world around us, appreciating and giving thanks, accepting things we regret by putting them into the context in which they occurred, seeking purpose and also self-forgiveness and finally growing, by looking back and seeing how far we have come and knowing there is growth still to come. Dr. Rotbart suggests that we have to discover miracles around us in order to appreciate the non-miraculous moments in our lives, that is, discover the magnificence around us. Live like you are dying and don't put off important things to the future. Accept that there is something greater than us, whatever your unique belief may be, and be humbled by knowing there are some things that are out of our control. Connect with Doctor Rotbart at: Twitter: https://twitter.com/harleyrotbart Facebook: https://www.facebook.com/harleyrotbartmd/ Website: https://www.harleyrobart.com LinkedIn: https://www.linkedin.com/in/harley-rotbart-m-d-4817a66/ Contact Dr. Gillian Lockitch to learn how you can decelerate your aging trajectory, stay vibrant and vigorous, or start your own online business in wellness and anti-aging:Email: askdrgill@gmail.com Website. https://www.askdrgill.comEmail me to book a complimentary Living Younger Call Order your copy of Growing Older Living Younger: The Science of Aging Gracefully and the Art of Retiring Comfortably at www.gillianlockitch.com

What if the most powerful determinant of how you age is not your biology, but your inner dialogue? In this episode, Anne Poirier explores how self-talk shapes emotional wellbeing, behavior, and ultimately healthspan. Negative inner dialogue can reinforce stress, limit confidence, and influence lifestyle choices that impact aging. Drawing from her lived experience and three decades of professional work, Anne explains how shifting from self-criticism to self-compassion can transform both mental and physical health. Listeners will learn practical strategies to reframe their inner voice, adopt body neutrality, and support healthier, more empowered aging. Anne Poirier is a nationally recognized body image expert and founder of Shaping Perspectives. She is a certified Intuitive Eating counselor, self-talk trainer, and eating disorder specialist with a degree in Exercise Science. She is the author of The Body Joyful, Not a Fat Annie, and The Body Neutrality Playbook. Episode Timeline 00:00 – Welcome and introduction04:30 – The role of self-talk in shaping behavior and identity 05:06 – Anne's early experiences with body image and eating disorder 10:32 – How childhood messaging and environment shape self-talk 16:39 – Body neutrality vs body positivity explained 18:37 – The "body bully" and transforming inner criticism 23:02 – Steps to heal your relationship with your body 25:16 – How self-talk impacts physical health and aging 30:03 – Overview of Anne's books and frameworks 32:41 – One simple daily practice to shift self-talk 34:45 – Wrap-up and key takeaways Where to connect with Anne Poirier https://shapingperspectives.com LinkTree: https://linktr.ee/annepoirier11 Free gift: Body Confidence Unlocked https://shapingperspectives.com/confidence/ Call to Action Download: Holistic strategies to Build Back a Better Body Schedule a complimentary introductory call or video call Contact Your Host: Dr. Gillian Lockitch Find Growing Older Living Younger: The Science of Aging Gracefully and the Art of Retiring Comfortably (North America only) or on Kindle Join the Growing Older Living Younger Community Subscribe to Growing Older Living Younger on your favorite podcast platform and leave a review to help others discover the show.