Dr Valter Longo is a longevity researcher who developed the fasting-mimicking diet, and this conversation reveals why 16-hour fasting increases mortality risk, how true autophagy takes five full days to activate, and why high protein might be accelerating ageing.

Valter explains why skipping breakfast and 16-hour fasting correlates with higher cardiovascular disease, despite faster results, 12-hour eating windows show zero negatives in studies. Learn why the five-day FMD uses low protein and high fat to trigger fasting while feeding gut bacteria, how less than 10% of people reach age 70 disease-free, and why blocking growth hormone pathways makes organisms live dramatically longer.

00:00 Daily fasting duration recommendations
04:02 Development of the fasting-mimicking diet (FMD)
10:30 Concerns about water-only fasting effects
14:07 Application of FMD for disease prevention and longevity
21:51 Completing the fasting cycle with proper refeeding
25:09 The debate on protein sources and intake
32:48 Protein intake for muscle growth and longevity
38:16 The relationship between strength training and longevity
50:20 Stress and its interaction with food and health
54:35 Key lifestyle factors influencing longevity

DISCLAIMER
Nothing shared on this podcast is a substitute for professional medical guidance. Please consult a healthcare professional before making any health or lifestyle changes.

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