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Case

I am a 27-year-old female student with relapsing-remitting MS treated with oral cladribine four years ago. I recently graduated from university with a BSc. I am currently studying for a master's. I have remained stable on MRI scans but continue to have difficulty walking. I understand that cladribine is an induction therapy, meaning that further treatment is not usually required after two courses. How effective is a third course of cladribine (Mavenclad) in halting disease progression?

NOTE: General substack newsletters and microsite are free; only Q&A sessions are restricted to paying subscribers. I can't run and maintain the MS-Selfie microsite, hence the need to pay people to help me do the work. If people want to ask medical questions unrelated to the Newsletters or Podcasts, they either need to become paying subscribers or email (ms-selfie@giovannoni.net) to request a complimentary subscription.

Prof G’s answer

Q&A 55: Should I have a third course of cladribine?