Is your NAD+ supplement actually working against you?

Millions of people are taking NMN or NR thinking they're doing something smart for their longevity. And the science behind NAD+ is genuinely extraordinary. But the way most people are supplementing it is incomplete — and there's growing evidence it could be creating downstream harm most people never connect back to their supplement.

In this episode I break down the full NAD+ story — the methylation trap, the CD38 drain, why high-dose NMN may be elevating your cardiovascular risk markers, and what an intelligent systems-level approach actually looks like.

I co-developed NAD+ Next Gen with Peter Lehrke— and in this episode I walk you through exactly why every ingredient is in the formula.

WHAT WE COVER: - The 2023 Nature Cardiovascular Research findings on NMN & ADMA - How high-dose NMN drains your SAM pool and disrupts dopamine, DNA methylation and homocysteine - CD38 — the biggest NAD+ drain in ageing nobody talks about - The bathtub model: precursors, drains, sirtuin efficiency - Why niacinamide may be smarter than high-dose NMN - EGCG, resveratrol, apigenin, quercetin, rutin — the why behind each ingredient - 6 practical takeaways including which blood test to get now

KEY LINKS: NAD+ Next Gen → https://aevumlabs.co.nz Rejuvenate Pro → https://shop.lisatamati.com Pushing The Limits community → https://www.lisatamati.com

GET YOUR HOMOCYSTEINE TESTED: Optimal: below 7–8 µmol/L Above 10 µmol/L: address your methylation cycle urgently

Lisa Tamati is a functional health practitioner, longevity specialist, co-founder of Aevum Labs, host of Pushing The Limits, and former elite ultra-endurance athlete with 25 years and 140+ ultramarathons across the world's most extreme environments.

Visit Lisa's website

www.lisatamati.com

shop.lisatamati.com

www.longlifehyperbarics.com

www.aevumlabs.co.nz

www.Yourhealthcompass.org

www.Myimmuneage.life

Work with Lisa: