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Baron Delaver
NAD is so important. It's so centered to biology that without it, you'll be dead in 10 seconds. Wow. As you start getting older, the NAD production starts declining. That would be like one year. The apple orchards might not give as many apples. Then they will be like your organs. Like maybe your liver is not processing alcohol that well, so you cannot recover from having those two glasses of wine.
Podcast Host
If boosting NAD turns back the clock in your cells, will people literally see fewer wrinkles on their skin?
Baron Delaver
Some people say that the aging spots. Older people have age spots. Yeah, they do report that their age spots disappearing. All the studies show that exercise is magical. It doesn't have to be crazy. You don't have to be Iron Man. But it's moving around. Even that's a big difference.
Podcast Host
Welcome back to the Real Foodology podcast. Today I'm joined by Baron Delaver, the entrepreneur and innovator behind Wonderfeel, a healthspan focused biosciences company advancing the science of healthy aging. We dive into the critical role of nad, the molecule that fuels our cellular energy, and how its natural decline with age shapes the difference between simply living longer and expanding our health span. Baran breaks down why NAD precursors like NMN matter. How wonderful. Combines NMN with powerful antioxidants to support DNA repair and cellular resilience. And what the research is showing when it comes to energy, cognition, skin health, inflammation, and more. We also explore the foundations of health that matter most, the future of nutraceuticals, and how Wonderfeel is making high integrity, clinically backed supplements more accessible. Thank you so much for listening. If you love this episode and if you're loving the podcast, please take a moment to rate and review. Please, please, please, please. I beg you. Every week. But seriously, it helps the show so much. If you want to see it grow, this is the easiest way you can support me. It's free, it takes two seconds, and it really means a lot. So thank you so much for listening and I hope that you love the episode. Also, check out the show notes for a link to find Wonderfeel. I'm huge fan of this product. Well, first of all, thank you so much for coming on today. I'm so excited to have you.
Baron Delaver
Thanks for having me. Yeah, I'm a big fan of what you do on the food world with the politicians.
Podcast Host
Well, I love what you're doing with this product. And we were talking a little bit before we started filming. There's so much information about nad, and I think a lot of people are confused or maybe getting it wrong. So what were you just telling me about nad?
Baron Delaver
Yes, there's a lot more hype for a good reason. But then, yeah, there's a lot of confusion about NAD and NR&MN, but the NAD itself. So the way I kind of explain to people is with an analogy. So think about NAD as the water source that feeds a valley. Like, think about a river going through a valley. There are small towns, there are orchards, there are farms. People are fishing in that river, people are using for transportation. So it's essential to the life in that valley. So NAD is so important, it's so centered to the biology that without it, you'll be dead in 10 seconds.
Podcast Host
Wow.
Baron Delaver
It also takes place in 500 enzymatic processes, and about 70% of it goes into energy production inside the mitochondria. So those are very technical terms, but people understand that. Oh, so it feeds the water, is used for the orchards. And what really happens is as you start getting older, the NAD production, the level of NAD you have, starts declining. And in our analogy, that would be like, one year, the apple orchards might not give as many apples the other year. Maybe the strawberry fields are not producing as many strawberries, and they will be like your organs. Maybe your liver is not processing alcohol that well, so you cannot recover from having those two glasses of wine. Or maybe your brain is not functioning as fast, as quick as it used to. So. And as the years pass, pass, pass by in a knowledge, the water might get more polluted, and also there's less fish. So that is the reason that, you know, most people have a different experience when they start raising their NAD levels, because everybody is different. Somebody who's really healthy, in our value analogy, probably everything comes down proportionally. So they don't probably recognize that, you know, they have a little less apples that year, a little less strawberries, because everything is balanced. But if the entire orchard goes out or, you know, you have all sort of no fish, you realize that there's something quite wrong that needs to be fixed.
Podcast Host
And we were talking earlier about, I kept saying longevity, and you said, I actually like the term healthspan, and I've talked about this before in the podcast, but can you explain again what the difference is between them? While you're more focused on health span than you are specifically on longevity.
Baron Delaver
Yeah. So, I mean, longevity is a wonderful field, and there's a lot of research going on. And the goal in the longevity space, especially the ones that excite me, the longevity biotech space, is to extend lifespan dramatically. So right now, the ceiling is like 115, 118. Nobody has lived till 130, 140. And also most people's eye, like in their 80s, 70s, 80s. So how can we make dramatic increases in those or average lifespan? I mean, in the last century, it went from like 50 to hundreds.
Podcast Host
That's pretty wild. That was a pretty big jump.
Baron Delaver
That's a pretty big jump.
Podcast Host
Although what's really fascinating to me right now and concerning is that, you know, so many people talk about modern medicine and we actually are living longer lives, but it's actually recently starting to decline. And not only that, so. So I don't think people are fully understanding yet that it's actually starting to decline and we're starting to go backwards right now. But on top of that, when you look at the quality of life, which is why I really like healthspan, because, you know, it's one thing to say, oh, my grandpa lived till he was 95, but if he was in a wheelchair for the last 10 years of his life because he really didn't take care of his body, is that really a life worth living that you want to live?
Baron Delaver
And that's the health span that we would like to improve. So we're gonna live healthier if we. If we're gonna live longer.
Podcast Host
Exactly. We wanna be as mobile as we possibly can. I use this all the time. I talk about this example. My parents are in their 70s, and they're still skiing, they're still hiking, they're very active. And I'm so excited about that because I want my parents to be around for my grandkids, and I want them to have energy to do all that. And I'm very happy that they're not losing that mobility. And they're on, you know, 10 prescription drugs that I'm. Unfortunately, we are seeing that in our older generations now. I mean, most of them are on average about 10 prescription drugs. It's really concerning. Okay, so health span from that perspective, why do you really like nad? And what is nmn okay for.
Baron Delaver
For health? Spaniard, the goal is to live healthier for longer because with age comes diseases, right? Like the Alzheimer's, heart diseases, diabetes. It's all is relevant to, for one reason or another, something to do with age. You don't get Alzheimer's in your 20s. You don't get, you know, diabetes comes usually a little bit later. So as we explained, NAD is so essential to biology. So what we have seen in the last five to 10 years is a lot more. More studies showing that raising the NAD levels helps the body to cope better and slow down aging. So if we can push those diseases coming on, we are in a good shape.
Podcast Host
Yes. Yeah.
Baron Delaver
We talked about confusion about nad. Well, first of all. Yeah, why is it important? And why do people experience different benefits by raising their NAD levels? But there's a lot more confusion. Number one is like, you can't really take NAD. NAD has been known since 1906, but only recently we have discovered that you can take precursors, building blocks that your body creates and buildings also every day. NAD is something. Your body creates billions every day, but it's created inside the cell. So how do you. If you take nad, just like these supplements, it does not go inside the cell. The NAD is very precious for the cell. So the cell membrane doesn't slip out. The same cell membrane doesn't also let NAD in. So that's where NMN and NR come into play. NMN is nicotinamide mononucleotides, and NR is nicotinamide riboside. So they, like NR, turns into NMN most of the time. And then nmn, there's a specific receptor outside of the cell that grabs nmn, flips it in size, and there it turns into nad. Okay.
Podcast Host
So it allows it to actually get through to the cells. And you've mentioned a lot of people are taking oral nad. I've also seen a lot of people do patches. And then I know a lot of people that do injections and IVs.
Baron Delaver
Yes.
Podcast Host
Would that be a different delivery mechanism for NAD, or is it still the same, that it won't cross over the cell?
Baron Delaver
So that's very interesting. People do IVs, injections.
Podcast Host
I've heard the IV is very painful.
Baron Delaver
Though some people do report pain. There hasn't been almost any clinical studies on those, but some people report some benefits. And so the interesting part about that is you're flooding your system with nad. So that's not how your body usually makes nad. So you're flooding high amounts of nad. And from that's not my theory. The Chief Medical Officer, Dr. Salzman Theory is potentially the body figures out some way to turn some of that nad to 12mn to bring it inside the cell. Because your body is smarter than us most of the time and has magical ways to cope with excess amounts of things or theories. Yes, Some of it probably gets in because you flood your system so much. It would be nice to see some studies showing, like, how the AD levels where it matters and tissue and cells go up. But it's a difficult process. You have to go to A specific place you have to have a nurse practitioner that have to put a needle inside you. And there's not a lot of evidence, but some people report benefits. So.
Podcast Host
Yeah, I'm curious to hear, I'm curious about that too. I've always avoided the NAD IVs because I've heard of the, the painful aspect of it. And also there are pain. Oftentimes you have to sit there for, you know, five hours because they have to push it in so slow. Right, right. And I also too, I mean, this is a little bit off topic, but I just saw a recent study where they found that we're getting a lot of microplastics in our blood from IVs. And I don't say that to scare people from getting IVs, because if you need a life saving IV, of course do it. But I'm kind of at this point right now where I'm feeling like, okay, I kind of want to save the IVs for, you know, God forbid there's an emergency and maybe do all of my nutraceuticals in a different way because of that concern with IVs, taking this.
Baron Delaver
Orally is very safe and it's proven it's easier.
Podcast Host
Yeah, exactly. It's so much easier. I can just take this at home. I don't have to go get a nurse practitioner or have to do injections myself. So tell me, is NMN really worth the hype?
Baron Delaver
I think it's going to become much more common. Yeah, it's, it's very different than your like antioxidants in polyphenols. You know, as again mentioned, like there's your lithium A, there's CoQ10, there's all these beneficial compounds out there. But this is so essential to the body that I think we're going to see more and more studies, we're going to see more and more people taking it, adopting it. We already have phenomenal feedback from customers and some of them really surprise us. Going back to my Dali analogy. Oh, like there's persimmons in that valley. We didn't know. There's some benefits that we don't expect and we hear. And then later on some study or some sort of a trial explains it and starts making sense.
Podcast Host
Are you able to share any of the customer feedback you've gotten? And of course you can say it's anecdotal and you can't make any claims. But are there certain things that have really shocked you that customers have said they've experienced?
Baron Delaver
There are some funny ones. There's some expected ones, like people's energy is good, but they have more energy, but it's more sustained energy. It's not like that. They take it, they feel more energetic. But after two weeks you're like, ah, I have more energy. I wake up like, you know, quicker and the recovery from alcohol, et cetera. But the funny ones. So my wife, she started taking it before anybody else, like during COVID and then you know, she doesn't usually put much makeup on anyways, but we are going to a Christmas party and she's like, well, let me just put some makeup on. And she's like, wait, I have full grown eyelashes. Because a woman in their 40s, 50s, they start losing their eyebrows or eyelashes. So she lost most of her eyelashes that I didn't necessarily recognize. Yeah. But yeah, she was stunned. So people will tell us like, oh, my white hair is going back to its original color. This is like after a year, like fascinating. It's like, oh really? Is that because of our product? And we also have a formula, it's not just nmn.
Podcast Host
Yeah.
Baron Delaver
And we have quite a few different occasions recognized just versus nmn. This is the one that has those more interesting results like people's eczema. Go to. Eczema is a very difficult hoaxin immune disease and they try all kinds of steroids like and they try it and after a while it starts working. So this has been consistent. Like people come back and say, well, I didn't use anything so I have to be very careful. These are anecdotal stories. So we are doing a clinical trial on eczema specifically with our formula because we tried just giving nmn and there's another phenomenal ingredient in there. Comes from mushrooms. Very good. Finding the battlepost to speak about.
Podcast Host
Let's talk about it. What is it?
Baron Delaver
Yeah, yeah. It's one of the most beneficial ingredient or active elements of mushrooms mostly like porcinis, lion's manes, cordyceps. These are kind of expensive, hard to find mushrooms. And the way we came across it was about 15 years ago, one of our friends mother suffering from Alzheimer's, severe case of Alzheimer's. And they were looking for alternate ways to help her case. And one professor recommended them to feed her a bunch of porcini hummus in the morning. And sure enough, she'll behave really well. She'll be very much better. Shape, function better. Why is it because ergot thionine. So what is this ergothioneine? It turns out that actually it's been very interesting by A very, very small group of scientists, UC Berkeley sign Professor Dusa aims at doing cultural longevity vitamin. So not many people know about Hertz, but Andrew Saltzman, chief medical officer got super interested and then we started doing research. And it turns out that it's prevalent in mother's milk. Babies have a receptor for it. We all have a receptor for it. So a baby who's one year old baby clearly benefits from it. Somebody who's got Alzheimer's at the age of 85 benefiting from it. So it's a wide range. And then we ended up actually talking to the Nobel Prize nominee in 2021 for his work on antioxidants and vitamins. So in his 80s and he was so happy to hear from us. It's like all this work brought me to ergo finding is in an Alzheimer's clinical trial. And the preliminary reports actually just results got reported and it looks very promising. And then what we learned from him is it's an adaptive antioxidant. So it collects in the body for up to 30 days where there's tissue damage. So there's puma and tox don't like that. But you cannot produce it yet to get it from your food source. And the theory is that our food supply has changed so much, the agricultural practices has changed so much that now there's only mushrooms left that has this greatly beneficial compound. So with that one professor, he really wants us to put it back into the agricultural practices on what his idea was. Yeah.
Podcast Host
I wonder how you would do that. And I wonder where we were finding it in other places.
Baron Delaver
Do you know some vegetables, I forgot what they are. But it's not enough. It's such small amounts. If you take mushrooms, like if you eat a good chunk of mushrooms, then you get, according to our understanding, enough herbal thye. It's very interesting. It's fasting. When we started, it was so expensive to us, $100,000 a kilo.
Podcast Host
Wow.
Baron Delaver
So we had to be very precise about the amount to put in there. Right. Like what is the right tool.
Podcast Host
That's so cool. You said something that I just I clocked that I find really fascinating. And it's a little bit off topic, but I just think it's so cool that we keep finding these different components in nature. Plants, plants, female and herbs and stuff where our bodies have receptors for them. And I was just thinking about we have this whole cannabinoid receptor system as well that responds to cannabis, which is also a plant being grown on the earth. And then now we also have this receptor system for these mushrooms. And it makes me wonder what other receptors we have for specific plants that were for finding in the environment. That's really cool. It'll be fascinating to see what other things we find. Right? Yeah. It's just that it comes back to that notion of, you know, you and I were talking about briefly about pharmaceuticals. And I have a question to ask you about that in a second. But something that's always really fascinated me about medicine in general is that most pharmaceutical drugs actually start from an herb or a plant or something that we find in nature. And then they usually mimic it or they mess with it a little bit. And it just, it comes back to largely, a lot of my message is that we're. We're getting so far away from nature that we're getting sicker and more depressed. And it just. When we start seeing all this science that's connecting us back to nature and all these plants and herbs and things that we need that are actually providing what our body needs, it just makes me so excited and it makes me feel like we're really onto something. And I'm like, yes, let's keep digging down those rabbit holes instead of doing these synthetic things. Because there really is a lot of. There's a lot of science and research behind it and things that can actually really help us and they don't have to have so much harm in our body.
Baron Delaver
Yeah, I mean, pharmaceuticals have their place, right?
Podcast Host
Yeah, absolutely.
Baron Delaver
So it's liars. But it's very difficult or no pharmaceutical company right now is interested in doing research on something readily available in a mushroom. They can have carcinos.
Podcast Host
Well, that's the problem.
Baron Delaver
That's the problem. So that's why I think there's going to be a new way, very hopefully, to be able to bring these natural compounds back into also pharmaceuticals. Not the way the pharma industry does right now, but if there's a different way to be able to bring these back into the system.
Podcast Host
Well, and you were talking about there's a way that your company wants to do this where you can actually get into the medical system where doctors can start prescribing them. Can you explain that? Because I thought that was a really cool concept.
Baron Delaver
Yes. Well, the challenge is that the medical field, most doctors actually, they will not prescribe something that has not been gone through the process and has become a pharmaceutical. But then the challenge we are talking about is all these beneficial foods and natural ingredients. Nobody is going to put hundreds of or tens of twenties of millions of dollars behind Them because they cannot patent. So somebody else can just sell it like right next to them at like a fraction of the cost. But I do think there's, there's a, there's a gateway in between that. So our goal is to be able to. Because the product does have some medical conditions and we see it and then how do we convince doctors to get behind it? As you need to go through the phases and make it also a prescription drug. But you know, to, you know, the maximizing profits is not the goal here. The goal is to make it more accessible. If you make a good product, it will end up being used and to give us enough support to run our business. We can do that. So there are different ways that we're exploring to be able to bring these natural compounds into the pharmaceutical space. We've done a lot of research, not a lot to show for yet, but I think we're getting very close.
Podcast Host
Is there a concern about fake M and M products or nad products on the market? Like for example, Amazon? And I'm always very fine from Amazon. So what are your thoughts on that? And also how can consumers navigate that and know that they're getting, I mean, obviously they should just be buying Wonderfield, but just maybe in general about supplements. How do they know?
Baron Delaver
Yeah, I have the same concern. And unfortunately a lot of the brands out there, they don't have what they claim they have in there products. Which gets trickier. They might have swordsmanal of whatever ingredient they claim to have. What about toxins? Have they done a good job? Where does it come from? Does it come from a chemical facility from overseas? Does it come from clean pharmaceutical or GMP facility? So unfortunately, fortunately, that's the beauty of this country. The consumer needs to do some of the, some of the homework. I recommend them to really look for third party certified certifications and ideally the certification as a QR code where you can, you know, go to the code and see where the certification comes from. The lab.
Podcast Host
Yeah.
Baron Delaver
Is to have it over there on their website, ideally.
Podcast Host
And do y' all do third party testing? Okay. Because I, I always tell people too look for companies that are actually doing third party testing. And even better if they're posting their coas, just look for companies that are as transparent as possible. And personally I always say I don't ever buy supplements off Amazon unless of the. If it's the store from the company, you have to sometimes do a little bit of digging. But if you know that it's being sent from the company itself, then I'm okay. With buying it. But otherwise, if you're just buying random brands on Amazon, I don't trust it.
Baron Delaver
We've seen a lot of granite 7 very poor products on Amazon.
Podcast Host
Yeah.
Baron Delaver
Because they don't regulate us well.
Podcast Host
And I've been hearing that there's a lot of fake NAD products out there where some company will send it to a lab or just some person will send it to a lab and test it. And most of them have NAD in it or it has really small amounts.
Baron Delaver
You're not supposed to have an ad. So an MN or NR is what you want in the product because NAD doesn't get inside the cell. But most of them did not even have NMN or nr. And again, like, I will question my. How clean the product is as well.
Podcast Host
So let's talk about. There's some other nutraceuticals in Wonderfeel, and I want to know why you specifically picked all of these and how they all work symbiotically together, especially trans. Is it trans resveratrol or is it just resveratrol? I think it's trans resveratrol, right? Yes, that's in there. Okay. I'm very interested in resveratrol. It was for its effect on mitochondria and also health span, which I hate calling longevity, but just anti aging benefits. I feel like it's really good for that.
Baron Delaver
Yeah, this retrofit was very interesting. It's been actually popular for a long time and it became a little controversial among the longevity circles.
Podcast Host
Oh, really?
Baron Delaver
Yeah, yeah.
Podcast Host
Why is that?
Baron Delaver
Because some of the benefits that they were claimed they were later studies could improve them. So there's one specific professor from Harvard who was very big on this one, and some people don't like him as much. So they used, I think, some of newer science to show that this science is not trustworthy. Anyways, it's treated controversy, but it seems to be a very good compound. And one challenge that we have with resveratrol is always stability and bioavailability. So in our case, we don't use much of it. It's a smaller amount on the grounds, I believe, per serving. And what it does, it activates something called sodulants. So these are enzymes that are in charge of building tissue, repairing tissue, hospital DNA repair. So they're very important. And one of the things that just came out, one study that just came out, I think respiratory can be connected to it. It's not connected yet is they looked at people who are over 100 years old in Japan and they Looked at their tissues, their blood, composure, and see if there's anything unusual. And they found, sure enough, something unusual. And they thought that first that could be a bad sign. You know, getting older, some things are whack. But then they discovered, no, actually, there are certain type of T cells that fight their immune cells, that help with tissue repair, that help with basically removing the cancer cells. And they're removing senescent cells, which are the dead cells that are floating around.
Podcast Host
Yes, the zombie cells in episode about this.
Baron Delaver
Yeah, yeah. So those cells, they definitely require an ad. They need an AD to be active and happy. But certains also work with those cells as well. So. So resveratrol has this indirect way of helping different enzymes in the cell.
Podcast Host
Oh, that's really fascinating to be healthy. Well, because I've heard, and again, we're making no claims here. I've just. I've heard of cancer patients going on and trans resveratrol, and I'm wondering if it's because of the effect it has on T cells. As far as. From. From an aging perspective, I'm really curious to know. So if nad, if boosting NAD turns back the clock potentially in your cells, will people literally see fewer wrinkles on their skin?
Baron Delaver
Some people say that the aging spots, okay, disappear. So older people have age spots.
Podcast Host
Yeah.
Baron Delaver
Right. So they do report that their age spots is occurring.
Podcast Host
I would just. I would think that especially for the aging spots. That makes a lot of sense to me because you think about regeneration of the cells. And I would assume, does NAD have an effect on regeneration of the cells? I mean, you said that it gets rid of the senescent cells, the zombie cells. So I would assume that there's some sort of regeneration happening there. Correct.
Baron Delaver
What helps with DNA repair? So DNA repair is key in rejuvenation. For your cells to be up to optimal, we need energy.
Podcast Host
Yeah.
Baron Delaver
I need the mitochondria to be healthy, need the cells to be healthy. And then your skin is constantly, like, exposed to damage. Right. You don't go out. There's oxidation, there's oxygen stress, there's UV lights. So how does your skin. How does your cells fight against this stress? So NVT is key in fighting that.
Podcast Host
What other signs of aging does NAD really combat? So is it. Is there joint things that people see? Are there just overall mobility, a better feeling of energy? I've heard that nad a lot of people, when they supplement it really consistently, they feel really high energy.
Baron Delaver
I will say an important one is cognition, because your brain consumes incredible amounts of Energy. And as you age, like, it's becomes a simple energy issue that people's cognition is not as good because their brain doesn't have enough energy. So you see some real big impact on certain people who suffer from cognitive issues. But even younger people, they get this focus on clarity. That's Aussie. So that's a big one. I don't want to get into the medical conditions, but with agathione there are some improvements on certain things, like the neurodegenerative issues become less of an issue, I would say, with consistent use. So those are like main signs of aging. They've done a small clinical trial and they've seen people's insulin sensitivity not getting better. It's a long list, actually. It gets confusing sometimes. That's why I go back to my analogy. Yeah, the valley, the different orchards. So everybody could benefit potentially differently depending on what their specific issue is. But the big ones, sleep has been a big one because the older people get, the harder it is for them to sleep. So we get great reports on sleep. Yeah, that's a long list.
Podcast Host
Yeah. Sleep and, well, an overall health span. So I think people are just probably seeing a better quality of life because as their cells are working better, they're getting rid of those old cells that don't serve their body anymore. It's repairing DNA. I would assume that it's also having some sort of effect on mitochondria. Have you done any studies on that?
Baron Delaver
We have done a few studies on specifically inflammation markers. We have done specific studies on inflammation and see how NMN affects inflammation, how the combination affects inflammation. And inflammation, especially chronic inflammation, is one of the biggest problems and causes of aging.
Podcast Host
Yeah.
Baron Delaver
So we've seen great improvements. So our challenge is to be able to. I mean, some of the preclinical work that we've done has been very impressive. The numbers are so impressive that we're trying to repeat it. But the repeat ones have not hit the same exact crazy high marks yet. So that's what I need to do a lot of work. Hopefully we'll be able to show that pretty soon. But it's an important one. Right. I've been able to bring the inflammation down, and that's where the story of CD38 comes into play. So that's an enzyme, that's an inflammatory enzyme, that's an immune enzyme. Some of them is good, but as you age, also goes into overdrive. A lot of it can come from leaky gut, but it's everywhere. As it goes up, it really consumes a lot of NAD. It just shoos away NAD. So you want to bring down the CD38 activity. And there has been some pharmaceuticals that haven't been in the market, but people tried to come up with some pharmaceuticals, but it turns out that these natural compounds, resveratrol and hydroxy tyrosol, for instance, from. And olive oil, they actually work great with reducing CD38 activities of all natural compounds.
Podcast Host
Oh, you know, I think I've heard of. Okay, I think I've actually heard of that before because I've heard of people taking olive oil in order to get those numbers down to help reduce inflammation and stuff. You know, it's just. So it's tough in the supplement world because you may be seeing all these amazing things happening with your customers, but you're not allowed to make these claims. And I understand why that's there, but it just. It kind of becomes tough because when you compare to a pharmaceutical drug, for example, which, you know, you and I talked about this earlier, I try my hardest to really avoid pharmaceutical drugs. And in fact, I'm 99% of the time not on any other. Any pharmaceutical drugs because I would rather take natural compounds that I also know have been proven to work. But the problem is, in order to be a pharmaceutical drug, you have to go through really extensive clinical studies and clinical trials, which is great. And I'm not opposed to that, but I'm just saying. So there's just a lot of work to do it. And then also they have to be able to patent it most of the time. And so in order to be able to patent something, because you can't patent anything made in nature, they have to tweak it a little bit and then it becomes, you know, farther away from nature. Yeah. And so it makes it really tough for supplement companies. And I can imagine for someone in your position where you're like, I have this amazing product and I'm going to make all these claims because I'm seeing all this cool stuff, but I can't legally make all these claims because I don't, you know, so we need to have all the clinical trials in the pharmaceutical backing in order to actually make those claims.
Baron Delaver
Plus, it's a long process. You have to go through the clinical phases. The safety. Safety is usually the easiest part because of the second round. Yeah. But then the efficacy, and then once you get through all the phases, then you get the approval of a. I think that's a pharmaceutical. It's actually one interesting fact that I didn't know about it. That's not where I come from. Turns out that a lot of pharmaceuticals are not super effective.
Podcast Host
I'm not shocked by that at all.
Baron Delaver
But it's effective enough that it cures or treats diseases. And again, they come really handy in difficult situations. Ours is we're not going after some really crazy hard to cure medical conditions like life threatening conditions. Because of the way FDA defines medical conditions, something simple becomes hard for us to be able to claim against. But other companies have found ways to explain how the product works and could you kind of get an understanding? But it's a very expensive process and you know, there's really no incentive for companies to do it because you can't take it on passengers. So it's difficult.
Podcast Host
I know. And this is where I really struggle with the pharmaceutical and the medical system. Because the reason that I try to stay away from most pharmaceutical drugs is that in my experience what I found is that these pharmaceutical drugs are not fully, I hate to use the word cure, but they're not fully getting rid of the problem. So what ends up happening is people are just on these pharmaceutical drugs for life. And that, that's where I have the issue of it. And, and I, you know, and that's where it's, it's a big moneymaker and it's a beautiful business. But when you think about somebody who's actually wanting to, you know, we've been talking this whole episode about longevity and lifespan and improving your quality of life. What you want to do is improve all those markers in your body so that you're not decrepit and hunched over and potentially in a wheelchair on a walker when you're in your 90s or even younger. I mean, people are in their 60s now.
Baron Delaver
Yeah, but I mean, I think you're talking also about the system, like going into prescription solution first. Right? You come from the world of like food first. Like you have good food, so have some exercise. If you don't do those things right, we cannot fix you. The pill, no matter how good of a pill is, it will help to a certain degree. So whether it's prescription, pharmaceutical, nutraceutical, they're not your solution, they're supplements. That's what it is, actually.
Podcast Host
Yes, that's very true and that's such a great point. In order for something like Wonderfeel to have the maximum amazing benefit in your body, it's also going to help having a good sleep regimen and drinking clean filtered water and eating whole real foods and exercising and just making sure that you're already keeping your body in Tip top shape and then adding something like this, I mean you're going to be like super fan. So what is the biggest lie in the healthspan longevity space that you're seeing right now? Biggest lie or myth or something that you're seeing and that you're just, it's making you so frustrated.
Baron Delaver
I do like what biohackers do. Like they go out there, they have crazy claims, some of them work, some of them don't work. Like red light therapies and ice baths and turns up. I think ice baths for women is trickier than men because temperatures are different. You should probably, probably know better. But you know, science usually catches up with those people later. Like people are out there experimenting and exploring new things and making claims, making crazy claims. So there is some risk that comes with it, but they're willing to take the risk. So I guess the question is which one of them have jumped from the pioneers into mainstream. That could be risky. So I would say maybe taking way too many supplements. You really pharmacy.
Podcast Host
We literally just have mind connection. Because I was going to say the exact same thing.
Baron Delaver
Yeah.
Podcast Host
Because we're, we're seeing the. I don't want to call him out, but I'm going to lovingly call him out right now. Like Brian Johnson's beholder. Even Dave Asprey, who's a friend of mine.
Baron Delaver
Yeah.
Podcast Host
But I've seen them take these handfuls and handfuls of supplements. And I was actually talking to a friend about this this morning and I was explaining to her because she asked me, well, what are your maybe top five, 10 supplements that you really, that you love and that you consistently go back to and that you tell other people to take. And actually I was like, I love the longevity stuff. I'm super into like nad, nnm, PC phosphatidylcholine is another one that I think is amazing. And the science behind it is so cool for cleaning your cells. But there really are only a couple now because I was explaining to her I have supplement fatigue. And I also don't think that we need to be taking so many. I think we need to find a couple things that really work on a deep cellular level. Something like this where it's really, really going to give you the maximum benefit and then you don't need to be chasing all this other stuff.
Baron Delaver
I think so. I mean there's also the risk called polypharmacy when it takes so many things.
Podcast Host
Yeah.
Baron Delaver
We don't know how they're going to interact with each other. Trying to get Most of them from food is ideal. And some food, you can only get them from food. People always ask us, you have vitamin D3 in there, why don't you put vitamin K? Well, because you can get K2. Vitamin K really is readily available, right?
Podcast Host
Yeah.
Baron Delaver
For food sources.
Podcast Host
It's a great point. And also it's a good point of thinking about how they're interacting together because we don't have any sort of studies about that. And it horrifies me to see people take all these different supplements. I'm like, oh, it's too many. And also it's hard on your liver.
Baron Delaver
And if it must be right, I mean, they're taking like 150 supplements a day. I don't know how they do a lot.
Podcast Host
So what would you say are maybe the top three things that will have the most benefit on longevity and lifespan?
Baron Delaver
The magic pill is what I hear is exercise. Yeah, Stress, I believe stress, human connection. Those are the ones that keep popping out as like the ones which have the most impact on what you eat of humans that process first as toxins. You're constantly feeding yourself toxins. But yeah, extreme stress, anxiety seems like it causes a lot of toxic reactions in the system, in the body. And we keep seeing all the studies show that exercise is magical. It doesn't have to be crazy, it doesn't. Don't have to be Iron Man. But just moving around, even that's a big difference. What do you think?
Podcast Host
I would also add on to that. So we studied this in my master's program in nutrition, and there was a study that was done where they actually found. Now a lot of people get triggered when I talk about this because it's a very fine line between this and an eating disorder. So I do want to be very clear. But they did find that maintaining a diet where you're not overfeeding and overeating a mass amount of calories all the time has a massive impact on the aging of your cells. And it's about to me, the way that I read that, when I read that in school, I was like, wow. The way that I saw that is how can you maximize the benefits of the most nutrients out of your diet? So getting really good high quality protein, high quality fats so that you get to a point where you're really satisfied and full. So I'm not saying you should be starving all day at all. By no means. I've gotten my diet dialed down to a point where I don't really snack that much because I get really full and satisfied. And I'm not thinking about food all day. And I've dialed it down to this point where I just eat really nutrient dense food and I feel very satisfied and full and I don't feel deprived. And I've found kind of this window of where I just, I'm not eating all day, essentially, is what I'm trying to say. And I think over snacking, overeating, overconsumption of excess calories does have an effect, aging in your body. And inflammation too.
Baron Delaver
Absolutely. And so these things trigger each other. Like the healthier you get, the healthier you eat, you kind of feel, you know, that you want to exercise more. Yeah. And like the sugar, this addiction, like the more sugar you have, it's not good to satisfy your sugar needs. Right. So you have to figure out what kind of foods to eat to that, not fill that.
Podcast Host
Sugar addiction and sugar too. There's also in that study about how sugar causes glycation, which is aging of your cells. And people that eat really high quantities and really high amounts of sugar, you can actually, you can see the effects of the aging not only on their cells, but usually on their face and on their skin. That to me I find so fascinating. And I always come back to this notion of food really is medicine. It just is. It has all the vitamins, minerals, nutrients, everything that we need for our bodies to survive. Yeah, it's really cool. Oh, I was going to ask you too about. I'm so curious if you know anything about, if you've looked into this at all. But, you know, a lot of people are talking about blue zones right now and there's a lot of different concepts about, around longevity where they say it's, you know, living in community and eating real food and walking everywhere and staying really mobile. I'm wondering if anyone has studied what their NAD levels look like in blue zones. Have you looked into that?
Baron Delaver
The study I talked about, they looked at, you know, they didn't measure their nad, but they looked at, you know, what's, what's different themselves, blood. And what they saw was the T cells.
Podcast Host
Yeah.
Baron Delaver
So that's the first one that we can point our fingers to as far as the main biomarkers go. And yeah, I mean, that's directly relevant to your NAD levels too. Like those T cells. We need to have NAD to function well.
Podcast Host
Okay, that's really fascinating. Someone should do a study and test and see what their NAD levels look like.
Baron Delaver
Right. Maybe you guys can do that. Right. I mean, it's not that easy to measure NAD levels like you just.
Podcast Host
Oh, really?
Baron Delaver
Measuring it in blood doesn't necessarily solve the. So gives you the answer like it's some sort of indication.
Podcast Host
Yeah.
Baron Delaver
But, you know, what matters is like, what the tissue. Tissue is like, the measurement is much harder. Take tissue out. Oh, and it's very stable. He's not very stable. So decal.
Podcast Host
Okay, so there's not actually a real biomarker. I wonder if there's any. Any sort of biomarker that you can.
Baron Delaver
Measure an AD in blood. But that's not.
Podcast Host
But that's not going to tell you what your stories are.
Baron Delaver
No. Yeah, that doesn't. Yeah. Give you the right answer.
Podcast Host
Okay, so I didn't think about it like that. That's really interesting. Okay, so. I mean, there has to be a connection. I'm also curious. I know I mentioned to you before we started recording it, and maybe you don't know the answer to this, but I've been asking. So I've been having a lot of conversations on the podcast about health span, longevity and mitochondrial function. Something that I'm really focused on and curious about right now is fertility. Do you think there's any effect on fertility? And our ovaries and our eggs and, you know, the DNA in our eggs with NAD and nmn. Do you think it's having an effect on our fertility health?
Baron Delaver
I forgot to even mention we get great reports and then there's some leading OBGY grants, doctors they are recommending, and they're also importing really good results. And it makes so much sense because, you know, your oocytes, your eggs, they. Mitochondria is key into the quality of your eggs is dependent on the quality of your mitochondria, the quality of your cells, your overall health. So I think it's much more common now when, you know, people are trying to get pregnant, they are put on a much better diet and they're trying to get their mitochondria as optimal as possible. And AT plays a huge role because the mitochondria uses HA to create energy.
Podcast Host
Yeah, we were talking about this. I'm very excited to see where this goes because this is very new. In fact, I think about. Very new. I mean, I think about when my parents were having children, no one thought about, oh, you know, we need to do a cleanse and make sure that our DNA and our mitochondria is really clean. And, you know, we need a detox and all this stuff. And now all my friends are doing this. I mean, my husband and I have been on this journey for the last year. We Just got married in June. We just spent the last year completely overhauling everything. You know, we got tests done. We wanted to make sure we didn't have any heavy metals and environmental toxins. And you know, we've been doing some detoxes and taking certain things that are really good that they're scientifically backed for the mitochondria. And it makes to me, it just makes so much sense. And what I would love to see is more studies being done on things like, you know, nmn nad urolithinase. Something else I'm really excited about just because of the studies or the science behind how it's affecting the mitochondria. And in my head I just think, you know, of course common sense, it, it's going to of course have some sort of effect on it. We just need to have the data and science to back it up.
Baron Delaver
Well, I'm very excited that very soon the largest trial is coming on led by Neo Medical School. We are part of Adrenal sponsoring it. They were kind enough to invite us. I think they like what they contribute. There's hundreds of hundreds of people, both male and females, that are going to be taking nmn different doses and the results are going to be public. Good or bad, it's going to be out there. So I mean they, there's a company, I think it's called RNA the one they have fertility clinics and they're the ones that are behind it. So I applaud them for their efforts.
Podcast Host
That's really exciting. Well, I'm excited to see what comes of that. It'll be really cool. Do you have any other clinical studies that you want to do or maybe you have down the pipeline that you're excited about?
Baron Delaver
Do we want to do so many that one of them. I cannot talk about it, but it's a very basic condition that most of us suffer. So I can't wait to have a product that side effect is longevity. If the pharmaceutical solution. What's the side effect? Longevity or a better health span. I mentioned we're looking into starting our clinical trial on the eczema.
Podcast Host
Yes.
Baron Delaver
Because people are reporting really good results, but we just don't know how long it takes, what doses necessarily. And if the first results are promising, we'll go further into it.
Podcast Host
I'm curious to see if this will have an effect. I'm going to have my husband start taking this. He has had psoriasis for the last 10 years and we've been on this journey for the last two years trying to figure out and it's gotten way better. We've really gotten a handle on it, but we want to get it fully clear. And I'm wondering if this will have an effect on it. So I'll report back anecdotally, of course, but I'll report back what happens with that. That'll be interesting to see. Is there anything else? Let's see that you really feel like people need to understand about nmn, nad, maybe Wonderfeel specifically.
Baron Delaver
I think dosage is super important that people need to understand. Some of the earlier studies actually were even done with smaller doses and some of the results were not impressive. So we think that's because of the dosage. But we know that the optimal dosage is super important. So ours has 900 milligrams of NMN. So for it to work, you need to take, in our opinion, at least 600 per day. And the range right now is 600 to 1200. Some people are pushing that. I hit more mostly. I mean, it's again something your body produces. So it seems to be super safe. We haven't seen any red flags so far. So dose she has the claims like there's people say the pozoma is better, the sublingual is better, this is better, that's better. None of them is proven, most likely that those products don't work that well because there are so many problems, potential problems, NMN ours or somebody else's that don't clean. NMN is proven to work. There are always questions about, well, people say NR is better, NMN is better. We don't see it as one side is much better than the other. They both work really well. So both NMNR effective NAD precursors, but the rest of them are not really NAD precursors. So if people are trying to sell NAD or some make other claims about some other ingredients really being at nad, improving nad, increasing NAD levels, I would not buy those products.
Podcast Host
Okay, that's really good intel. And do you feel like we kind of talked about this? But I want to ask very specifically, the different nutraceuticals that you put in there, are you really finding that those are what maximize the benefits of the nmm?
Baron Delaver
Also, ergothioneine, we talked about respiratory. So they do have a specific function. And some of them are not even. No on ricers they were selected that we didn't want to put too many things in there because these we know they work. And the clinical trials that we are preclinical trials we are doing is also showing how synergistic beta work. Better on certain biomarkers, I guess, especially inflammation. And we are seeing the positive results. But conceptually also these couple of them are the CD38 inhibitors. So if think about if it's a tub you are trying to fill nad tub and you know your spigot is like putting less because you're aging, but then there are big holes on the lean seam, so you want to make sure that you plug those holes. So that's a couple of our ingredients serve that role as well, reducing the leakage, if you will. And then the ergothione is a really phenomenal active ingredients that I think more and more studies are going to come out on hypothymine that again, babies benefit from it and people with Alzheimer's benefit from it. And it's that. So we see the benefits on certain skin conditions.
Podcast Host
Really, really fascinating. Well, I'm curious to see if we see any benefits with the, with the psoriasis. I want to know specifically what your longevity routine is. If you have one. Okay. Or health span, I should say what your health span routine is.
Baron Delaver
Well, eating healthy, good thing. I love to eat. So eating fresh produce, some sort of exercise. So I prefer to do things that I love like snowboarding and kite surfing, but they're not always readily available. So then not get on a bike or a quick one. Or the bands, the elastic bands, exercise bands. Very practical.
Podcast Host
I love it.
Baron Delaver
Yeah, you don't have to carry a whole bunch of weight around.
Podcast Host
And they're really easily packable too because I travel a lot. You probably do too.
Baron Delaver
Some supplements. Yeah. So again, I try to take my supplements from food. So Omega 3 is a tricky one. We all hear about great things about omega 3. And I eat a lot of seafood usually, so I sometimes take it. Sometimes don't take it. I'm trying to sleep. Well. Yeah, but the more you work out, the easier you sleep. But it's not always to spend a few hours. Sketch your finish. Snowboard.
Podcast Host
Yeah, exactly. I also love snowboarding. So you said that and I was like, yes, love it. I love snowboarding. Well, I got through all of my questions. This was really fascinating. Oh, I remembered my question. I would ask you, is there anyone that can't take nmn? Like I would assume you probably have not tested for during pregnancy. So I would assume probably not during pregnancy. Do you know anything about breastfeeding while you're breastfeeding?
Baron Delaver
We don't know. Yeah, you don't know. I would say young people, they love to take it, but I don't think there's a need for it or it's not proven. So if you're in your 20s, I mean, like the Kardashians, they do IV, VD, IVs, and I think they started in their 20s. Yeah. I think it's too young. So what we usually say is like, you know, start at your, like when. Once you're 30.
Podcast Host
Okay.
Baron Delaver
You don't need to start before those. There's nothing to prove. There's no, no proof that it's gonna help you when you're 18 years old. Well, I would assume 20 years old. Yeah.
Podcast Host
Yeah. I would assume at that age, your body probably has a lot of nad and you don't need to add on more.
Baron Delaver
That's our assumption. Yeah.
Podcast Host
Okay. Well, thank you so much for coming on. And please, Baron, tell everyone where they can find you and where they can find Wonderfield.
Baron Delaver
Well, thanks so much for having us. Thanks so much for listening to us and our stories and our goals. Yes, you can find them at www.getwonderfield.com. that's where we are.
Podcast Host
Awesome. Well, thank you so much for coming on. This is fascinating.
Baron Delaver
Thanks for having us.
Podcast Host
Yeah, thank you. Thank you so much for listening to the Real Foodology podcast. This is a Wellness Loud production produced by Drake Peterson. Theme song is by Georgie. You can watch the full video version of this podcast inside the Spotify app or on YouTube. As always, you can leave us a voicemail by clicking the link in our bio. And if you like this episode, please rate and review on your podcast app. For more shows by my team, go to wellnessloud.com See you next time. The content of this show is for educational and informational purposes only. It is not a subscription, constitute for individual medical and mental health advice, and doesn't constitute a provider patient relationship. I am a nutritionist, but I am not your nutritionist. As always, talk to your doctor or your health team first.
Beth Cameron
If you struggle with bloating, gas, constipation, digestive issues, yeast overgrowth, well, you may already know about Digest this. It's the podcast hosted by me, Beth Cameron, also known as Little Sipper on Instagram. I dive into gut, health, nutrition, the food industry, and drawing from my own experience, I break down what's good, what's bad, and what's the best for your gut, your skin, and so much more. I even offer gut friendly recipes. New episodes every Monday and Wednesday. Produced by Wellness Loud.
Episode: Can You Actually Slow Aging? NAD, Longevity, and Healthspan Explained | Baran Dilaver
Guest: Baran Dilaver, Entrepreneur and Innovator behind Wonderfeel
Date: January 27, 2026
This episode dives deep into the science and practical realities behind NAD (Nicotinamide Adenine Dinucleotide), its vital role in cellular health, aging, and the difference between pursuing “longevity” versus “healthspan.” Courtney is joined by Baran Dilaver, founder of Wonderfeel, a biosciences company focused on healthy aging, to break down NAD metabolism, the use of NMN and other precursors, supplement quality, and how lifestyle—more than “magic pills”—drives real, lasting vitality.
“NAD is so important, it’s so central to biology, that without it, you’ll be dead in 10 seconds.”
—Baran Dilaver [02:00]
“Is that really a life worth living that you want to live? … That’s the health span we would like to improve.”
—Courtney Swan [05:27]
“People will tell us like, ‘Oh, my white hair is going back to its original color...’ It's fascinating.”
—Baran Dilaver [12:29]
“No matter how good of a pill is, it will help to a certain degree. … They’re not your solution, they’re supplements. That’s what it is.”
—Baran Dilaver [34:58]
Clinical Trials & Aspirations:
Healthcare System Limitations:
Effective Dosages:
Who Should/Shouldn’t Take NMN?
On NAD’s Centrality:
“NAD is so important, it’s so central to biology, that without it, you’ll be dead in 10 seconds.”
—Baran Dilaver [02:00]
Differentiating Healthspan:
“Is that really a life worth living that you want to live? … That’s the health span we would like to improve.”
—Courtney Swan [05:27]
About Natural vs. Synthetic Medicine:
“We’re getting so far away from nature that we’re getting sicker and more depressed.”
—Courtney Swan [18:17]
On pharmaceutical innovation and nutraceuticals:
“No pharmaceutical company right now is interested in doing research on something readily available in a mushroom.”
—Baran Dilaver [18:46]
On lifestyle vs. supplementation:
“No matter how good of a pill is, it will help to a certain degree. … They’re not your solution, they’re supplements. That’s what it is.”
—Baran Dilaver [34:58]
Polypharmacy Caution:
“There’s also the risk called polypharmacy when you take so many things. We don’t know how they’re going to interact…”
—Baran Dilaver [38:03]
This episode distills why restoring and protecting NAD levels is a promising frontier in delaying age-related decline—not just living longer but living better, with more energy, clearer cognition, healthier skin, and greater resilience. However, Baran and Courtney caution against the “magic bullet” mindset: foundational habits remain essential, and supplementation should be smart, safe, and evidence-based, with transparency and authenticity at the forefront.
Where to learn more or purchase:
Wonderfeel: www.getwonderfeel.com [53:33]
For listeners craving vibrant health and cellular resilience in their later years, this evidence-rooted conversation spotlights both the promise and the proper place of NAD precursors like NMN—as a supplement, not a substitute, for a healthy lifestyle.