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Heart disease has long been framed as a “man’s disease” – but women are being missed, misdiagnosed, and overlooked in ways that can be life-threatening, especially within South Asian communities where cardiovascular risk often develops earlier and more aggressively.

In this episode, Dr. Komal Patil-Sisodia sits down with advanced imaging and preventative cardiologist, Dr. Ambreen Mohamed, to unpack the evolving science of women’s cardiovascular health, the hormonal shifts that impact risk throughout midlife, and why prevention needs to start far earlier than most people realize.
Together, they explore the subtle symptoms women experience that are too often dismissed, the intersection of menopause, PCOS, pregnancy complications, insulin resistance, and heart disease, and why traditional risk calculators frequently fail to capture the realities of South Asian patients. Most importantly, this conversation reframes prevention not as fear-based medicine, but as empowerment: understanding your risk factors early enough to change the trajectory of your health before disease develops.

Connect with Dr. Mohamed:

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Instagram
Website

Connect with me:

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Eastside Menopause & Metabolism

Audio Stamps :
00:00 – Dr. Komal introduces Dr. Ambreen Mohamed and sets up the conversation around women’s cardiovascular health, prevention, and South Asian risk

00:00 Podcast Mission Setup

01:05 Meet Dr Ambreen Mohamed

04:38 Why Women Get Missed

07:10 Women’s Heart Attack Symptoms

11:18 Hormones Menopause PCOS Risk

15:06 Pregnancy As Stress Test

18:36 Menopause Hormone Therapy Debate

25:59 South Asian Heart Risk Factors

28:02 Advanced Lipids Lp(a) ApoB

33:07 MASALA Study And Risk Tools

36:27 Perimenopause Lp(a) Spike

37:18 Estrogen and Lp(a) Research

38:11 Who Counts as High Risk

39:55 Doctors Still Learning

42:12 Labs to Ask For

43:31 Insulin Resistance Markers

46:15 Beyond Labs and Blood Pressure

47:52 Sleep Apnea and Heart Risk

48:41 CAC Score When It Helps

50:12 CT Angiogram and AI

54:32 Lifestyle Changes to Start Now

58:48 Advocating at the Doctor

01:02:31 Wrap Up and Where to Find Her

01:04:25 Final Takeaways and Call to Action

Thanks for listening. Find more info about Clearly Hormonal on the website or Instagram.