
Hosted by TdC · PT

Joanne Alves e Marcela Belleza convidam Raphael Barreto para discutir sobre a vacinação no adulto, dividindo o tema de forma prática em 4 pontos: conceitos básicos de vacinação, vacinação no jovem hígido, vacinação no idoso e vacinação no paciente imunossuprimido.Referências:1. https://www.gov.br/saude/pt-br/vacinacao/publicacoes/instrucao-normativa-que-instrui-o-calendario-nacional-de-vacinacao-2026.pdf2. https://sbim.org.br/images/files/notas-tecnicas/informe-sbim-esclarecimentos-vacinas-hpv-240415-v2.pdf3. Gagneur, Arnaud et al. “From vaccine hesitancy to vaccine motivation: A motivational interviewing based approach to vaccine counselling.” Human vaccines & immunotherapeutics vol. 20,1 (2024): 2391625. doi:10.1080/21645515.2024.23916254. A. Heidenreich, P, Bhatt, A, Nazir, N. et al. 2025 Concise Clinical Guidance: An ACC Expert Consensus Statement on Adult Immunizations as Part of Cardiovascular Care: A Report of the American College of Cardiology Solution Set Oversight Committee. JACC. 2025 Nov, 86 (21) 2085–2098. https://doi.org/10.1016/j.jacc.2025.07.0035. Johansen, Niklas Dyrby et al. “Electronic nudges to increase influenza vaccination uptake in Denmark: a nationwide, pragmatic, registry-based, randomised implementation trial.” Lancet (London, England) vol. 401,10382 (2023): 1103-1114. doi:10.1016/S0140-6736(23)00349-56. Larson, Heidi J et al. “The Vaccine-Hesitant Moment.” The New England journal of medicine vol. 387,1 (2022): 58-65. doi:10.1056/NEJMra21064417. Dinga, Jerome Nyhalah et al. “Quantitative Synthesis of Factors Associated with COVID-19 Vaccine Acceptance and Vaccine Hesitancy in 185 Countries.” Vaccines vol. 12,1 34. 28 Dec. 2023, doi:10.3390/vaccines12010034

Lucca Cirillo apresenta um caso de aumento de enzimas hepáticas para Amyr Chacar e Djoni Moraes.Referências em breve.

Esse tema foi abordado na edição 153 do Guia TdC. Para saber mais, acesse: https://www.tadeclinicagem.com.br/guia/542/manejo-de-hemorragia-digestiva-alta-nao-varicosa/. 🚨 www.tadeclinicagem.com.br/guia - Conheça o Guia TdC com 7 dias grátis 🚨

Aline Campos e João Mendes convidam João Felipe, residente de medicina intensiva do HCFMUSP, para discutir novamente sobre polêmicas da sepse, dessa vez abordando o novo Surviving Sepsis Campaign de 2026 através de casos clínicos. O tema já foi abordado anteriormente nos episódios #41 e #111. Referências em breve.

Raphael Coelho e Letícia Angoleri convidam Vivian Fernandes, residente em geriatria na UNIFESP, para discutir a abordagem de quedas no idoso, desde a abordagem inicial no PS e tratamento até a identificação de fatores de risco e prevenção. Referências:1. Welch SA et al. The Short Physical Performance Battery (SPPB): A Quick and Useful Tool for Fall Risk Stratification Among Older Primary Care Patients. J Am Med Dir Assoc. 2020.2. Centers for Disease Control and Prevention (CDC). About Older Adult Falls. 2026. 3. Moreland BL et al. A Descriptive Analysis of Location of Older Adult Falls That Resulted in Emergency Department Visits in the United States, 2015. Am J Lifestyle Med. 2021.4. Moreland B et al. Trends in Nonfatal Falls and Fall-Related Injuries Among Adults Aged ≥65 Years — United States, 2012–2018. MMWR Morb Mortal Wkly Rep. 2020.5. Albasri A et al. Association Between Antihypertensive Treatment and Adverse Events: Systematic Review and Meta-analysis. BMJ. 2021.6. Xu Q et al. The Risk of Falls Among the Aging Population: A Systematic Review and Meta-analysis. Front Public Health. 2022.7. Coulter JS et al. Falls in Older Adults: Approach and Prevention. Am Fam Physician. 2024.8. Pimentel WRT et al. Quedas entre Idosos Brasileiros Residentes em Áreas Urbanas: ELSI-Brasil. Rev Saude Publica. 2018.

Gabriel Paes apresenta um caso clínico de plaquetopenia para Kaue Malpighi e a convidada Mariana Tourinho, residente de Hematologia do HCFMUSP.Referências em breve.

Esse tema foi abordado na edição 134 do Guia TdC. Para saber mais, acesse: https://www.tadeclinicagem.com.br/guia/474/nova-diretriz-americana-de-2025-sobre-tratamento-de-pneumonia/🚨 www.tadeclinicagem.com.br/guia - Conheça o Guia TdC com 7 dias grátis 🚨

Jonatas Zanoveli e Ana Carolina Malvaccini convidam Alice Mendonça para discutir o que o clínico precisa saber sobre a Furosemida. Referências:1. Novak JE, Ellison DH. Diuretics in States of Volume Overload: Core Curriculum 2022. Am J Kidney Dis. 2022.2. Mullens W et al. Combining Loop with Thiazide Diuretics for Decompensated Heart Failure: The CLOROTIC Trial. Eur Heart J. 2023. 3. Ellison DH. Diuretic Treatment in Heart Failure. N Engl J Med. 2017. 4. Brater DC. Diuretic Therapy. N Engl J Med. 1998. 5. Felker GM et al. Diuretic Strategies in Patients with Acute Decompensated Heart Failure. N Engl J Med. 2011. 6. Marques P et al. Systematic Review on the Management of Diuretic Resistance in Acute Heart Failure across the Spectrum of Kidney Disease. Cardiorenal Med. 2025.7. Mullens W et al. The Use of Diuretics in Heart Failure with Congestion: A Position Statement from the Heart Failure Association of the European Society of Cardiology. Eur J Heart Fail. 2019.8. Frea S et al. Diuretic Treatment in High-Risk Acute Decompensation of Advanced Chronic Heart Failure: Bolus Intermittent vs. Continuous Infusion of Furosemide. Clin Res Cardiol. 2020.9. Tang WH, Kiang A. Acute Cardiorenal Syndrome in Heart Failure: From Dogmas to Advances. Curr Cardiol Rep. 2020.10. Yamada T et al. Systematic Review of the Association Between Worsening Renal Function and Mortality in Patients With Acute Decompensated Heart Failure. Kidney Int Rep. 2020.11. Mullens W et al. Acetazolamide in Acute Decompensated Heart Failure with Volume Overload. N Engl J Med. 2022.12. Diuretic Strategies in Acute Decompensated Heart Failure: A Narrative Review. Can J Hosp Pharm. 2024.13. Prata AA et al. Protocolized Natriuresis-Guided Diuretic Therapy in Acute Heart Failure: A Systematic Review and Meta-analysis. Crit Care. 2025.14. Ter Maaten JM et al. Natriuresis-Guided Diuretic Therapy in Acute Heart Failure: A Pragmatic Randomized Trial. Nat Med. 2023.15. Felker GM et al. Diuretic Therapy for Patients With Heart Failure: JACC State-of-the-Art Review. J Am Coll Cardiol. 2020.16. Chawla LS et al. Development and Standardization of a Furosemide Stress Test to Predict the Severity of Acute Kidney Injury. Crit Care. 2013.

Joanne Alves e Nordman Wall convidam Caroline Millon para discutir a abordagem da Síndrome de Apneia e Hipopneia Obstrutiva do Sono (SAHOS). Referências: https://www.tadeclinicagem.com.br/guia/458/sindrome-da-apneia-e-hipopneia-obstrutiva-do-sono-diagnostico-e-tratamento/Myers, Kathryn A et al. “Does this patient have obstructive sleep apnea?: The Rational Clinical Examination systematic review.” JAMA vol. 310,7 (2013): 731-41. doi:10.1001/jama.2013.276185Gawrys, Breanna et al. “Obstructive Sleep Apnea in Adults: Common Questions and Answers.” American family physician vol. 110,1 (2024): 27-36.Hong, Yanan et al. “The study of the relationship between moderate to severe sleep obstructive apnea and cognitive impairment, anxiety, and depression.” Frontiers in neurology vol. 15 1363005. 10 May. 2024, doi:10.3389/fneur.2024.1363005US Preventive Services Task Force et al. “Screening for Obstructive Sleep Apnea in Adults: US Preventive Services Task Force Recommendation Statement.” JAMA vol. 328,19 (2022): 1945-1950. doi:10.1001/jama.2022.20304Palombini, Luciana de Oliveira. “Critérios diagnósticos e tratamento dos distúrbios respiratórios do sono: RERA” [Diagnostic criteria and treatment for sleep-disordered breathing: RERA]. Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia vol. 36 Suppl 2 (2010): 19-22. doi:10.1590/s1806-37132010001400007Yeghiazarians, Yerem et al. “Obstructive Sleep Apnea and Cardiovascular Disease: A Scientific Statement From the American Heart Association.” Circulationvol. 144,3 (2021): e56-e67. doi:10.1161/CIR.0000000000000988Duarte, Ricardo Lm et al. “Obstructive Sleep Apnea Screening with a 4-Item Instrument, Named GOAL Questionnaire: Development, Validation and Comparative Study with No-Apnea, STOP-Bang, and NoSAS.” Nature and science of sleep vol. 12 57-67. 23 Jan. 2020, doi:10.2147/NSS.S238255Gottlieb, Daniel J, and Naresh M Punjabi. “Diagnosis and Management of Obstructive Sleep Apnea: A Review.” JAMA vol. 323,14 (2020): 1389-1400. doi:10.1001/jama.2020.3514Malhotra, Atul et al. “Tirzepatide for the Treatment of Obstructive Sleep Apnea and Obesity.” The New England journal of medicine vol. 391,13 (2024): 1193-1205. doi:10.1056/NEJMoa2404881

Frederico Amorim apresenta um caso clínico de perda visual para João Urbano e o convidado Yang Hu. Referências:1. Fraser JA, Son M, Vinokurtseva A. Sudden Vision Loss: A Diagnostic Approach. Am Fam Physician. 2025;111(1):54-61.2. Newman NJ, Biousse V. Approach to Vision Loss. Continuum (Minneap Minn). 2025;31(2):328-355. doi:10.1212/cont.0000000000001546