Isabelle Vitaly (3:36)

Oh, my gosh. Well, thank you for that amazing, like, testimonial. I love when I can help the kids, especially because that is my background is in pediatrics. Right. I started working for CeraVe, and so I was talking to pediatricians all the time about skin health. And you probably experienced this, Savannah. Like, they don't know very much about the skin at all. I would say, like, probably the number one question I got asked by them was, what's a ceramide? Because we were talking all about ceramides, and then, why should I care about the skin? They were literally asking me that, which is crazy. And of course, it's not all of them, but the ones in Michigan that I was coming in contact with, that's what we were hearing. So I love that we can be a solution to the babies. And, you know, I gotta say, so our origin story, me and you, Savannah. I don't know if you remember, but we met at IECSC and gave you product. And this was in March, so we were, like, fresh out of the gate. Nobody knew a single thing about us. I don't even think the packaging was actually like, fully final yet. But I had. Like, of course, you were getting swarmed by everybody and, like, you were, you know, trying to get somewhere, and I ran up and I gave you the bottles and I was like, hey, this is siv. Like, hopefully you like it, you know, being so annoying. And you were super sweet. You were like, oh, my God. Like, thank you. Whatever. So then when we reconnected now, back in November, December, you still had the bottles, which I gotta say, I was shocked. Like, I thought for sure that they were gonna be, like, in the garbage. Like, this, like, crazy girl brought me this product. Like, what is this? This is going in the garbage. So to your credit, it was so sweet that you actually kept them and you had them still. And that was amazing to see. So I'm so happy that you. Yeah. Still had those.

Savannah Boda (5:16)

Oh, yeah.

Isabelle Vitaly (5:18)

But, yeah. So I started in pediatrics. Now, for anyone who doesn't know, I don't have a background in science, I don't have a background in chemistry, nothing like that.

Savannah Boda (5:27)

I literally get my age, too, which is, like, so badass. Like, that's something else I just love is that you're a young and you are paving the way in this industry and making a life for yourself and, like, changing lives while doing it. And that is just so inspiring. I mean, this industry is very much male dominated, even when it comes to the CEOs and the people that are making the products and running the products. And I just love seeing more female founders, and I love seeing young females just shooting for the stars and obtaining their dreams and changing lives while doing it. So congratulations. If you have not told yourself this every single day, you should, because what you're doing is big work. I mean, it's not just another serum. It's not just another cleanser. It's something that has changed so many lives and helped so many people, and it filled a gap that so many of us were searching for.

Isabelle Vitaly (6:15)

Thank you. And I knew that if I wanted to go into this market, it had to be truly revolutionary and unique because, you know, nobody needs another cleanser. Nobody. Like, we've got things dialed in, right? So to penetrate that market, it really had to be something different. And, you know, I kind of stumbled upon this, to be honest. So I was doing a lot of research for these pediatricians who were asking me all about skin health, specifically things like eczema and baby acne and things like that. So that's how I even found out about the skin microbiome. And so I was like, wow, interesting. The skin has a Microbiome, this is pretty important for how the skin functions and. And all of that. So initially I had just Googled, like, products for the skin microbiome, and this was back in 2021. So because I was like, somebody surely had to have, like, figured this out, right? So nothing comes up, okay? I Google it and it's like an oil, and they're like, it's microbiome friendly. I'm like, cool. So that basically means it does nothing to the microbiome. It's friendly. So I was like, wow, that's so interesting. But whatever, I'm not going to do anything about it. I'm going to let someone smarter than me figure this out. So I just kind of, like, go on with my life. And I just had this whisper in the back of my head, like, I don't know, you should do something about this. And it was just something strange pulling me towards this. So by happenstance, I happened to be listening to a podcast, actually, and this podcast was talking about these bacillus spores. And these spores were revolutionizing the gut space. They were so unique. They're so resilient. They perform this really unique process of quorum sensing, and they're able to just balance out microbiomes. And I'm like, I wonder if anyone's ever used these on the skin. Or I wonder if because they're so resilient, they could be used in a cosmetic formula and survive. So I actually DM'd the microbiologist on that podcast, just randomly. I'm like, hey, I have this weird idea. What do you think about using the spores on the skin? And he's like, yeah, to his credit, he answered. And he's like, yeah, I think. I think that there's some utility here. I think that we could do something here. So I was like, okay, like, you know, I'm thinking about putting them in a formula or whatever. And he's like, you know what? Let me send you some to start formulating with. And I'm like, okay. So he sends me the spores, they arrive, and I'm like, formulating the product in my kitchen, literally, just from, like, research, like, using Paula's Choice Ingredient Dictionary and my own, like, brain of knowing, like, what products are really good for the skin and what ingredients are really good for the skin. Because my main objective here was not to, like, make some super complicated, crazy product. I knew that the spores would be utility enough. And so my main objective, to be honest with the carrier, was to get out of the way of the spore and Just allow a vessel for the spore to reach the skin and then let that spore do its magic. And, you know, I didn't know how to make an emulsion. I didn't know how to, like, do any of that. And that's why the serum is all oil based. Like, to be totally honest, it was just. I stumbled upon something so good, and I didn't even realize what I had when I was doing it, but it just worked out for the best. And now, like, the case studies that I had, the first ones are of myself and my friends. We all had acne, and I had a couple friends that had psoriasis and eczema. Across the board, we all saw amazing results. And for anyone who wants to look, if you go on my Instagram and, like, scroll down, it's so cute.

Savannah Boda (9:36)

One of those old school, like, e cig juice bottles.

Tyler Jacoby (9:40)

Oh, really?

Savannah Boda (9:40)

Yeah.

Tyler Jacoby (9:41)

I love that.

Isabelle Vitaly (9:42)

Yeah, yeah, yeah. That was the initial dropper because I was like, on Amazon, like, okay, how do I package this?

Tyler Jacoby (9:47)

I love that. No, it's amazing because the formula is pretty. I mean, simple to a point because there's, like, less than eight ingredients in it, right?

Isabelle Vitaly (9:58)

There's four ingredients. Four. It's Squalane, two fatty esters, and the spores.

Tyler Jacoby (10:02)

Wow.

Isabelle Vitaly (10:03)

That's it.

Savannah Boda (10:04)

That amazing.

Isabelle Vitaly (10:05)

I know.

Tyler Jacoby (10:05)

I've been copy and pasting that full ingredient list a lot when making the bundles and, like, and other products, like, this big. And then it's like, online.

Savannah Boda (10:14)

I love that. Yeah, no, it's amazing. I mean, it just really speaks to the spores that are, you know, really working their magic and doing wonders.

Tyler Jacoby (10:22)

Yeah. No, I mean, I. Going back to Savannah's story with it, like, I saw her struggle so hard with her son with it, because I don't want to say it made you feel like a failure, but it's. Yeah, okay. It did.

Savannah Boda (10:35)

It did. I'm like, I can do. I can heal acne. I can heal melasma. I can reverse aging. I help so many clients with eczema, but his. And that's the funny thing, is like, lipid serum and restorative. Ha. And hyacinth and comfort cream. Like, it was good for a lot of clients. It would be the prayer. I mean, it would clear them completely. But I'm like, of course. My kid. It just wasn't enough. It just wasn't enough. There was just, like, this missing key ingredient. I mean, God, I was at the science of skin summit or the Skincare of science summit. I always say it wrong, and I was going to every booth, because it's more a derm based meeting. And I was going everywhere to grab, you know, would you guys have anything for eczema? Do you have anything for eczema? And, you know, everyone gave me stuff. I'd try it just, it wasn't doing anything. And then sev. I mean, literally a day later, I was like, what's the worst that can happen? Let's try this. And my jaw still, to this day, is still on the floor. I still have yet to pick it up. Because, you know, it. Truly, I just. I just think it is the coolest thing, like, out of everything I've tried, like, you. You fixed it.

Tyler Jacoby (11:35)

And it's like. I mean, trying, like, the most complicated science. Like, I mean, like, they're paying for these technologies to be the cure for these things. And, like, all along, like, some, you.

Savannah Boda (11:48)

Know, doing it in her kitchen. I mean, like, that's literally the craziest thing. And I hope any young listener or anyone in general, doesn't matter what age you are here, is that, like, if you have an idea, like, and you don't think you're good, like, I'm sure for you, you're like, I'm not a chemist. I'm not an esthetician. I'm not a dermatologist. Like, who am I to do this? But you knew you had a mission, and you knew you had something special, and you pushed. And that takes a lot of courage. A lot of people won't do that. A lot of people will not push all the way through because of, you know, fear holding them back or not feeling good enough or, you know, just scared. Um, and I just think it is so amazing that you push through. And now look at you. Now look at your brand. Now look at where you're going. Like, this is just still the beginning for you. And I just can see, like, already before my eyes just, like, so many opportunities and just so many things happening for you. And I am so excited to be partnered with you and to help you any way that I can, because I just believe in what you're doing, and I am just so proud of you. I am.

Isabelle Vitaly (12:50)

Thank you. Thank you so much. I mean, yeah, it's been so inspiring the whole time to see the effect that we can actually have on people. Like I said, I had no idea what I was stumbling into. I'm an outsider from the esthetician world. I had no idea about this whole world. I had no idea about how incredibly educated estheticians are. They are insanely smart. When it Comes to the skin and knowing the questions to ask, understanding the mechanism of action. And this serum's not a simple mechanism of action. I mean, in our onboarding calls, I go through the entire science of the skin microbiome. I go through quorum sensing. I tell them what leaky skin is. You know, I talk about the differences that SIV can make in eczema cases. Like, you talk about how you tried all these different things, but we approach eczema in such a different way from that point of really targeting the staph aureus on the skin. And staph aureus is so tricky, Right. So like the colonization of Staph aureus, if we can. If we want to talk a little bit about.

Savannah Boda (13:45)

Yes, get in.

Isabelle Vitaly (13:47)

Okay. So eczema is characterized as having an abundance of staph aureus on the skin. Right. And staph aureus is so tricky to treat for a few reasons. So, one, it's robust, meaning it does not have a lot of competitors naturally on the skin. So when it gets on the skin, it can really easily overtake that microbiome. And there's not a lot that it can do to stop it. It's very hard to stop it. Now once it's overtaken the skin and kind of populated on the skin, it starts to attack the barrier. And it does that through ceramide levels. And so it really attacks through ceramide and filigreen levels. So you're left with this kind of collection of skin cells without any of this really like lipid to kind of hold them together. Right. So now we start to see tons of trans epidermal water loss. That's why it's so hard to keep proper hydration levels in the skin in those cases, because there's nothing to hold in it. So then your skin also starts to overpopulate or overproduce skin cells to try and compensate for this lack of lipid in there. So now you see the plaquing of the skin and all of this kind of scaliness that comes along with eczema. Along with that, this degradation is also leading to a lot of nerve exposure. So that's where you start to see lots of burning on the skin, redness, itchiness, all of this crazy, like discomfort that comes with eczema. So when we see this, we're like, okay, we need to treat the barrier because the barrier is literally being pillaged, right? So we use products then that will nourish the barrier, help the barrier to kind of grow these ceramides. Back maybe in some cases we're adding ceramides to the skin, other lipids that the skin loves. Well, this is the food that the Staph aureus feeds off of. So as the barrier is trying to repair, the Staph aureus is like, sweet. I get a new food supply, let's go. And it just starts eating away again. So it's really hard to break that cycle without actually targeting that staph aureus. So then we go to a steroid. Because a steroid, what we know it does is it suppresses that bacteria, but it does it artificially, right? So it's just artificially suppressing that and the bacteria around it. So everything is dampened at that point. So the barrier does have a reprieve. It's able to rebuild in those cases, but it's not doing it because there's actual competition on the skin that's changed the tools of the ecosystem. And the whole name of the game about a microbiome or an ecosystem is competition. And that is kind of where civ helps to facilitate these benefits, strains to increase competition and being able to out compete certain pathogens. So we add the steroid, it brings everything down. The skin does repair. We come off the steroid because we're like, oh, awesome. The skin's back. Like, we're fine. The barrier's back. But then what happens? The Staph aureus is like, I'm back. What's up? Like, I'm not gone.

Savannah Boda (16:23)

It's like a toxic ax that won't leave.

Isabelle Vitaly (16:26)

No, literally. And so we see this reflaring of eczema and then in some cases it'll be even worse because the entire immune system has been dampened for that period of time. And so it's completely miscalibrated. So the skin microbiome which controls the skin's immune system starts to respond to everything. And it's like, what's going on here? What's going on here? And this is all presenting as inflammation on the skin. So not only do you have these, this flare up of eczema, but you also have this overactive immune system that's causing just even more reactivity in the skin. And so that's where we start to end up with like conditions of like topical steroid withdrawal or just worse conditions of eczema. So it's a really vicious cycle, essentially. Right. And you're obviously really familiar with that. And so the way that SIV has kind of been able to change this a little bit is the spore itself in There. So we use bacillus spores. The spore itself is actually able to break apart this biofilm that Staph aureus creates. So a big part of treating eczema is breaking apart that biofilm, because staph aureus is smart and it protects itself. And it's like getting to me. So without breaking that apart, you're not even getting to the staff aureus. So you break that apart, you expose the staff aureus, and then the spore we have testing that, it actually is able to outcompete that Staph aureus. So it brings that Staph Aureus down. It's actively working to bring it down. While that's happening. This is the important part. It's facilitating competitors like Staph epidermidis. And Staph epidermidis is Staph aureus, his greatest competitor. So they have an inverse relationship. The more Staph epidermatis you have on the skin, the less Staph Aureus you're going to have on the skin. And so this is its greatest competitor. And we have tests that actually show we can bring this back to the skin, where people in their baseline measuring with none of this on the skin, it came back after they were using sieve for 14 days. So it's actively working then to create a competitor to be able to colonize the skin after that bacillus spore is gone, keeping that Staph aureus down. The other great thing about Staph epidermidis is it secretes this enzyme called sphingomyelinase, which actually gathers nutrients on the skin to funnel that to the body to produce ceramide. So not only are you eradicating this bacteria that erodes ceramide, but you're also facilitating a bacteria that actually helps the body to produce ceramide and outcompete that other bacteria. And it's interesting. Like, you can draw correlative lines. There's studies done on the amount of sphingomyelinase on the skin and the amount of ceramide within the skin barrier. So it's so interesting how connected everything is and this competition that's going on, it's just amazing.

Savannah Boda (19:01)

That is so cool to hear you talk about that. And, like, I love nerding out. And I just think it's so amazing that, like, she literally sent me when I asked her, I was like, you know, how many conditions can this treat? And she sent me, like, a whole, whole novel of every skin concern and, like, how it works. And so many companies can't do that. And they have like chief science officers and so many, like, you know, things going on. So I think that's so amazing. Talk to us about acne, because that was something. And I will be honest, I've still been a little, because of ptsd, has a tent to recommend for a lot of my acne clients. And I'm getting a little more comfy, you know, just, you know, dip my toes in. I'm like, we'll start with like eczema and dermatitis and then go. But, you know, you've seen. And really, you created this mostly too, for acne. So talk to us a little bit about how this works with acne and what you've seen. We've done some with fungal acne and had really, really good excess. But I want to hear a little bit more about the non inflamed side and the inflamed.

Isabelle Vitaly (20:01)

Yeah, totally. So acne is, is another function of kind of balancing the skin microbiome. Right. So we've actually done some microbiome testing on acne and our results were really interesting. So we had tested two clients and we did their microbiome swabs. So at their baseline, they each tested and they had acne. Now, the C. Acne strain is really interesting the way that it plays into all of this, because the C acne strain is good to have on the skin and it's not always the main driver of acne. A lot of times when it does become overgrown, it can trigger the immune system because that's normal part of how immune systems work. But it's not the whole story with acne. And actually, whether or not you're more or less acne prone can actually change the amount of acnes that you can handle on the skin without it triggering the immune system. So it's kind of interesting and it's such a good bacteria and a protective bacteria to have on the skin.

Savannah Boda (20:56)

Yeah.

Isabelle Vitaly (20:57)

Now, if you're really acne prone, you can't handle that much of that bacteria on the skin or else you're going to start to have acne and trigger acne. So in one of our participants, we swabbed his skin, his skin microbiome came back with 60% of his microbiome being composed of the C. Acne strain. So way too high. Right. So we, you know, have him use the serum for 14 days. Once a day, we see that strain come down to 13%.

Savannah Boda (21:26)

Wow.

Isabelle Vitaly (21:27)

So a 47 percentage point drop. It didn't eradicate it, but it balanced it and you can see in his before and after the total resolution of the acne, including inflammation in other areas of the face, too, that weren't as inflamed or were inflamed before. So, like, around his nose area and stuff, he had some inflammation which was gone. So that was amazing to see. Men. So our next participant, really interesting. We swab her skin. She also has acne. Her starting C. Acnes concentration is around 14%. Okay. So only 1 percentage point higher than where his trial ended. But she still got acne. So it was really interesting. Now after 14 days, we're like, okay, what's it gonna do? Because if it drops it at the same rate as the first participant, this acne is gonna be gone. After 14 days, it's gonna be eradicated. So after 14 days, we swab her skin. Her skin does a total 180. It looks really amazing. At the end, she's got no more acne lesions, and she had a lot of, like, tonality issues as far as, like, pie pih, crepiness, kind of things like that. And that was. Was pretty well resolved. So we see her C. Acne strain. It only comes down by two and a half percentage points. So 11.5%, meaning the spore was able to identify in this participant. Our first participant, the C. Acne strain is so highly elevated. We need to really bring this down. Now, in the second participant, maybe the C. Acnes wasn't as big of a problem, so it only brought it down by two and a half percentage points, but they still both saw clear skin.

Savannah Boda (22:57)

Wow.

Isabelle Vitaly (22:58)

Now, when we're looking at her corny bacterium levels, which corny bacterium is a bacteria that we would expect to find in a drier area. Right. We really wouldn't expect to see this on the face. Her corny bacterium was at around 15%, so higher than you'd expect to see it, which is likely the driver of a lot of this inflammation that we were seeing and some of this pie PIH creepiness, dryness, because it can actually erode the barrier. So when we looked at her after swab and we looked at the concentration of Cory bacterium, this bacteria was essentially undetectable. So the score is able to identify. Okay, maybe the C. Acnes isn't a huge driver here, but this cornea bacterium is really a problem. So we really need to bring this down where in the other one, it was really able to target this overgrowth of the C. Acne strain. And we see this over and over again, which it's so interesting to really look at it at a granular level like this. Because two people can present with the same or similar condition and have totally different needs in their microbiomes and totally different needs of those ecosystems. And that would explain, too, why it's like, no two routines may fit perfectly for. For one person. Like, for each person. You know, like, you can put two people on the same routine and have different results.

Savannah Boda (24:03)

Yeah.

Isabelle Vitaly (24:04)

Even when they're presenting with a similar condition to start with. And it's all because of those microbes in that ecosystem.

Tyler Jacoby (24:10)

So maybe I'm still a little lost or it hasn't been explained yet. Because I will say I was on the intro call. Savannah was, like, nerding out the entire time, and I think my head was just spinning because I don't know. Normally I like to think I'm smart, but that's not where I've.

Savannah Boda (24:27)

That's not your forte.

Tyler Jacoby (24:28)

Yeah, that's not where I put my focus on.

Savannah Boda (24:29)

If you're trying to tell me about, like, how to read classical music, like, I'd probably want to die.

Tyler Jacoby (24:33)

Sure. And like, this is your favorite part of your job. Honestly, I love nerding out.

Savannah Boda (24:37)

I love education. I love science.

Tyler Jacoby (24:39)

So what does the bacillus do in the skin that tell? Like, how does it. How does the skin know?

Savannah Boda (24:48)

Quorum sensing.

Tyler Jacoby (24:49)

Quorum sensing. Okay.

Isabelle Vitaly (24:52)

Yeah, you're right. So essentially, quorum sensing, and that's the main mechanism of action. I. This is a great question. I think a lot of people are probably confused at this point.

Savannah Boda (25:02)

Yeah. Like, give us, like, a Tyler level, like, not an esthetician.

Isabelle Vitaly (25:06)

Spores and bacteria. Cool.

Savannah Boda (25:08)

Yeah.

Isabelle Vitaly (25:09)

So essentially, the serum uses this bacillus spore, which does have the ability, this innate, wonderful ability to perform really adaptive and sufficient, efficient quorum sensing. Now, quorum sensing, at its root, it's communication between bacterial cells. So all cells are doing this at all times, but some cells are better at it than others. So within a given ecosystem, each microbe that's there has a proper concentration that it should be at. So, you know, all the cells are kind of communicating with each other, looking at the concentrations that they're at. And these concentrations are called critical masses. Right. So when a bacteria is reproducing within a given ecosystem, the microbes around it are constantly monitoring it, and they're. They're waiting for it to reach this critical mass. Once it reaches the critical mass, the microbes around it send these chemical signatures called autoinducers, and these stop. The reproduction of that bacteria says, okay, you're good. Stop reproducing now, that process in and of itself is quorum sensing. Okay. So when a bacteria, though, becomes, you know, too robust, or the quorum sensing signals get thrown off, that ecosystem gets thrown off. And that could be for any number of reasons. Climate, like, you know, environmental factors, products, hormones, internal stuff, like anything can throw off your ecosystem. Okay. When that gets thrown off and these signals don't get sent or they don't reach the bacteria, that bacteria can become overgrown. So then the microbes around it kind of catch it on the back end where it's like, oh, we have something overgrown. Now we have a problem. So they turn to the immune system to say, hey, we need backup here. We need help bringing this bacteria down. So then your immune system responds. It goes to that site, and that's what we see on the skin or even in the body as inflammation. So anytime we see inflammation on the skin or in the body, it's an immune response. And that's why these microbes, these different microbiomes, even in the gut, are so influential on the immune system because they're really the things that trigger that immune response. So the immune system responds, and that's what we see as inflammation or an immune inflammatory condition. So how does the spore work into all this? The spore is really good at quorum sensing. So it goes on the skin and it assesses the health of the ecosystem. It looks at what microbes are here, what comes in concentration, or they hear at, you know, what's going on in this ecosystem, and they're able to take in that information and then communicate it to the resident microbes. So the spore is transient. It's not engrafting into the skin. It's not colonizing the skin, which is.

Savannah Boda (27:46)

Different than the other products. So it doesn't stay right. They just come in. They're like little messenger bird, they're like. And then they fly away. Which brings me. Which I'm going to forget. But I want to ask you, what is the lifespan? Have you guys been able to test what is the lifespan? Once you apply, how long are they, you know, doing their job before they leave?

Isabelle Vitaly (28:06)

So it's a good question, and we do need to test that, because I'm really not sure. Typically, transient microbes are on there for a couple hours to maybe a day.

Savannah Boda (28:16)

Yeah.

Isabelle Vitaly (28:17)

So somewhere within that time. It's not very specific.

Savannah Boda (28:20)

And the reason I'm asking is because there were a couple days. My husband did not apply seb on Cyrus. And, you know, usually if we skipped a day of using something on him it would flare up horribly. And I mean, my husband went like three days without applying it this past weekend, no flare ups. And that's why I was curious, you know, how long, you know, because, I mean, it's pretty crazy.

Tyler Jacoby (28:43)

It's probably because before it was just minimized so it was easily triggered again. But I feel like now that it.

Savannah Boda (28:49)

Was gone, it's like balance.

Isabelle Vitaly (28:51)

Yeah, I think it may. It may more so be because, like when we did our microbiome testing, we didn't see an overabundance of bacillus and these people were like using CIV at night and then testing in the morning. So you would think that like that bacillus is getting metabolized overnight and it's no longer on the skin. So what I think was probably happening there was he may have like facilitated these competitors to Staph aureus to be able to keep that regulated long term. Because this does have the ability to actually correct the dysbiosis as long as it's topically driven. So in theory, people would be able to come off of this without having.

Savannah Boda (29:24)

It's not like a steroid withdrawal or sieve withdrawal.

Isabelle Vitaly (29:27)

Yeah, you won't have to draw.

Savannah Boda (29:30)

That's pretty amazing.

Tyler Jacoby (29:31)

I have a question. Are these bacillus spores naturally occurring on our skin, or is this something brand new that's being introduced to our biome? Or is this just something we already have but we don't have enough of?

Savannah Boda (29:42)

Good question, Tyler.

Isabelle Vitaly (29:43)

Great question. Yeah. So these spores are not something that we produce. They're naturally found in the soil. So if you think back to like our ancestors, we used to live in the soil. We always used to come in contact with them. So we did develop a symbiotic relationship. But we don't make them ourselves and we really don't ever come in contact with them either out in the wild anymore, on the subway way or in our car.

Tyler Jacoby (30:05)

Yeah.

Savannah Boda (30:06)

That's so interesting. That is so interesting. So what are some more niche things that you've used SIV for? Or I've heard of people using SIVON that you've seen good results with.

Isabelle Vitaly (30:18)

So I live in Michigan. Mosquito bites are huge. One like all of my friends will put them on our mosquito bites that are super itchy. It literally takes the itch out almost immediately.

Savannah Boda (30:28)

Oh, great. We put that on my back tonight because I literally have a huge one that's big. I've been like, like a bear on chair all night.

Isabelle Vitaly (30:35)

Totally. Yeah. You know, folliculitis, we've seen pretty good Results with. You can use it for the scalp, too.

Savannah Boda (30:41)

So, yeah, I've been getting a lot of inquiries for, like, psoriasis or scalp psoriasis.

Isabelle Vitaly (30:48)

Yeah. We've even had, like, alopecia areata just with the immune privilege, because a lot of that is immune privilege collapsing on the follicle. And so you have a lot of inflammation, inability for the hair to grow. So it's actually helped to reduce the inflammation. It's. I'm not going to say it makes the hair grow, because it really doesn't. It just helps to restore function to the follicle.

Savannah Boda (31:06)

You know what I mean? Have you seen anything for hs?

Isabelle Vitaly (31:14)

Hs? Hs.

Savannah Boda (31:16)

I mean, so I'll butcher it if I try to say it out loud. It's like, a lot of times on the armpit. It's a very inflammatory, like, nodules that women will get.

Isabelle Vitaly (31:26)

I don't know if anyone has tried it for that, but I would imagine that it would help. We've had someone for bv.

Savannah Boda (31:34)

For what?

Isabelle Vitaly (31:35)

Bv.

Savannah Boda (31:36)

Oh, that's amazing.

Isabelle Vitaly (31:39)

Yeah, I love that.

Savannah Boda (31:42)

Have you seen anything for kp? That was one I was curious about.

Isabelle Vitaly (31:45)

Really?

Savannah Boda (31:46)

Okay.

Isabelle Vitaly (31:46)

We need to get absolutely keratose plus. Yeah. A lot of people.

Savannah Boda (31:49)

Wow.

Isabelle Vitaly (31:50)

Absolutely.

Tyler Jacoby (31:51)

And then body acne.

Isabelle Vitaly (31:53)

Yeah, for sure. Definitely. Any of these, like, mystery conditions, too, that, like, you know, everyone. Every esthetician has been there where, like, someone comes in and you're just like, oh, I don't know what's going on.

Savannah Boda (32:04)

I mean, literally, that's.

Isabelle Vitaly (32:06)

Yeah.

Savannah Boda (32:06)

The key.

Isabelle Vitaly (32:07)

Yeah. It's amazing with my friends, like, we're all like, oh, if you have, you know, any problem, emotional, mental, physical, just put SIV on it. It's fine.

Savannah Boda (32:15)

I love that.

Tyler Jacoby (32:16)

And, you know, I love how attainable it is for everyone, too. I know that.

Savannah Boda (32:23)

Yeah.

Tyler Jacoby (32:24)

Like, you know, a lot of moms, like, if, say we're like 250, like.

Savannah Boda (32:28)

Like lipid serum one.

Tyler Jacoby (32:29)

Yeah, exactly.

Savannah Boda (32:30)

Like, it's like, that's hard.

Tyler Jacoby (32:32)

It's hard.

Savannah Boda (32:34)

Yeah.

Tyler Jacoby (32:34)

It's $68, and it lasts a really long time.

Savannah Boda (32:38)

Like, we only needed, like, two to three drops for size hole. Well, I mean, he's also a toddler, but, like, his whole area.

Isabelle Vitaly (32:45)

No, you're right. It's. It's only a small amount because the main objective of the product is not to coat your skin. It's almost like a topical supplement. Like, you just want to get the spores in contact with the skin. So, you know, you don't want to go, like, using way too much and feeling like you've put this coating over the skin, it's truly, like, should lay invisibly. So one to three drops is typically enough for the face. And, like, you said that, like, two to three or three to four drops for the body is perfect.

Tyler Jacoby (33:10)

Yeah. Because they. I'm sure they travel on their own a little bit.

Isabelle Vitaly (33:13)

Maybe they do. Yeah, you're right.

Savannah Boda (33:16)

They're travelers. They're like, I don't want to stay in one place.

Isabelle Vitaly (33:18)

I want to go see the city.

Savannah Boda (33:20)

I love that. I love that. Have you seen. And, like, the cool thing that I love for my clients, too, is you can still use it with your retinoids and other acids, and it plays nice in the sand pit, which is huge for clients that are on a regimen. Yeah, yeah. The other bioproduct I was working with, like, did not play well in the sand pit, so I was really happy to hear that, like, this was something that could be an addition to my clients with anything that they're struggling with. I mean, we've seen crazy results with perioral dermatitis and periocular dermatitis as well. So anyone that's getting acne around the mouth or around the eye area, this has been such a game changer. And it's really great post procedure, too.

Tyler Jacoby (34:01)

And, I mean, even people who have, like, allergic reactions, like, she got a message that where someone.

Savannah Boda (34:07)

Did you see that one? The hives? Did you see that?

Isabelle Vitaly (34:10)

Oh, my God. That was crazy. I screenshotted it. I was like, oh, yeah, you need.

Savannah Boda (34:14)

To use that in your little spank bank of.

Isabelle Vitaly (34:17)

Right.

Tyler Jacoby (34:19)

I mean, it's just insane how huge of a difference in such little of a time. I mean, I think that's the biggest thing to me is how short of a time period it is, because every other, you know, case study responsive with it. Yeah. Like, every other case study you look at, it's like, well, we need, like, 12 weeks of data. And I'm like, I'm sure that y'all did similar case studies as well, but really, for every case that we are getting reports on, it's like, we only.

Savannah Boda (34:43)

Need 48 hours worth of data or 2412 next morning. Put it on at night. In the morning, they're like, 90, 80% healed. Yeah, it's from one application is. I mean, that's huge. So let me ask you more personal. Did you. When you started this, did you ever expect it to be what it is right now?

Isabelle Vitaly (35:00)

No. I thought I was, like, gonna be doing this, like, on the side for my whole life. I was like, I had no like, when I tell you guys, I had no idea what I was stumbling on. I had no idea. And to see it now is literally mind blowing. Like, I pinch myself every single day. Like, I'm like, this is insane. What is happening right here.

Savannah Boda (35:20)

Just working through her, though, is so amazing. Like, it's just like, I truly believe and I don't get super religious on my podcast, as I. You know, we have followers from every religion and all of that, but those that know I am very, you know, in tune with my religion, with God, and I know you are, too. She sent me an amazing book, which I. I'm going to start cracking into when I get to the Maldives. Don't let me forget it. But I think it's so crazy, because when you are living through your purpose and when you're doing something for the goodness of others, it just works. It just happens. Like, it's just like something clicks and it's like. You know, I've always noticed in life when I was experiencing so much resistance trying to pursue a relationship with someone or a friend group or a career, that, like, was not what God wanted for me. It was just like roadblock after roadblock. And not to discredit our hard work, because we are hard working. Like, we put in the work. But, you know, when you put in the work and you're still getting all this resistance and you're like, why is this happening? I'm doing everything. It's like, you know, when you found this and when I found just skincare in general and being in aesthetics, it was just this mission to just help heal through skincare. And, you know, to see you doing the same and you're like, the same mage as I am, it's just truly so cool. And I think, I mean, you're way cooler than me. I didn't create a product. I didn't, like, freaking, like, crack the code to eczema like you did. But, I mean, it is just phenomenal to watch and see you grow. And I'm just, again, I will probably say it 30,000 times. I'm just proud of you. And just. You're honestly, fear. You're fearless. Like, that is something so huge to take the dive, to take the jump, to put yourself out there, to go to the shows, to, you know, come up to me and give me the bag. Like, that takes so much courage. And to see where you've gotten today in such a short amount of time. Like, babe, one year. So many companies don't get to where you are, like, 10 years or they Quit before they even get there. So I just hope everyone listening supports her and helps her grow because it truly is so amazing to watch and see. And again, it's not just another serum, it's not just another cleanser. Like this is something that's changing the game of skincare and also changing lives.

Isabelle Vitaly (37:33)

Thank you. I mean, I can't say thank you enough, but yeah, it's just been insane and your influence has been completely game changing. To be totally honest and yeah, fearless or delusional, I don't know, you decide. But I, I think you need delusion to be successful. You do?

Tyler Jacoby (37:51)

Yeah.

Isabelle Vitaly (37:51)

Like, I really think you do because yeah, if you don't believe in yourself, like why should anyone else believe in you? So you really have to. And I, I agree that like when it's your calling and when you are called to do it, things do fall into place. Like there's so many things that could have gone wrong. There's so many like lucky breaks that I had along the way to this point. And if it's supposed to work out, it will. And I'm sure, like I'll have more. Like people, I think also underestimate the role of luck in, in success. Like everyone has like certain lucky things that you know will happen that bring you to where you are and yeah, it's just been amazing. And to see the impact it's having is truly mind blowing and unbelievable.

Savannah Boda (38:36)

I love that. So we have a lot of people that listen that are not only estheticians but business owners or in different fields. And you know, as a young business owner, a young CEO, give us some of your biggest wins and some biggest lessons that you've learned.

Isabelle Vitaly (38:51)

Oh, biggest wins would probably be the connections. Like don't discount anybody. You know, going at it with the right purpose is a huge thing. And just making these key connections, like one person can literally change the game. And big or small, like, you know, Jen brought us on and she was incremental and like, I can't even tell you how much she helped grow our business. And in the beginning, like I didn't know who she was and like I just, I had no idea. And you know, nurturing that relationship and now we're great friends and she's just been so incredible and like people, she's amazing. I cannot say enough nice things about her. Like Cult Skin by Jen. Love you so much. So definitely connections are a huge thing and like you are who you surround yourself with. Always learning from people. Like, I think that's one of the most important things too, is like, something that I've really learned along this process is like, shut your mouth. Listen and shut your mouth. Like, that is. I'm one of those people who, like. I like to give my opinion. I like to talk. I like to, you know, like, spout off whatever about things that I think. And it's like, no, you don't know everything. You actually don't know anything, so shut up and listen. I think that's really important in business, especially being young and growing the company and kind of taking everything through a filter and analyzing it yourself. I mean, okay, what do I think about this and why do I think this? And so it's forced me to grow in a lot of ways, which has been really refreshing and really nice and really able to, you know, being able to reflect on that has been really cool. And it's illuminated parts of my personality that are great that I love and parts of my personality that I'm like, you know what? I think you need to work on this, you know, and that's what it's all about. It's all about growth and kind of figuring things out. And I am young, and there's a lot that I don't know. And realizing that is has been really important in this too.

Savannah Boda (40:55)

But youth is power because we have stamina, and you have many more years to go and many more products to create. Which brings me to my next question. Is there anything exciting or new coming up for Sev that you can share?

Isabelle Vitaly (41:07)

Yes, we do have. So we have a back bar size coming out, which is fun. Yay. And I'm excited about that. I am, too. Another thing we do have in the works, which I'm not sure when this will launch, but I'm excited about, it is actually a microbiome test. So being able to swab the skin and actually looking at, like, what is going on on the skin.

Savannah Boda (41:30)

Oh, my gosh. So that is phenomenal. That is going to be such a game changer. Now, is this going to be something that you have to do in an office setting or something that you can, you know, get at home and learn about your skin at home?

Isabelle Vitaly (41:42)

So right now I'm not really sure. I'm thinking it's going to be probably done through estheticians.

Savannah Boda (41:47)

Yeah.

Isabelle Vitaly (41:48)

Just because the instructions probably get confused.

Savannah Boda (41:50)

And be like, what the do these numbers mean? What am I gonna do?

Isabelle Vitaly (41:53)

Make sure that everything's done right and, you know, they start, you know, who knows what people do? So we're gonna keep it in office probably, but I think it'll be a great tool.

Savannah Boda (42:04)

Yeah, it's like, gonna be great.

Tyler Jacoby (42:06)

It's like a diagnostic, like Vizia.

Savannah Boda (42:08)

Yeah.

Tyler Jacoby (42:09)

Which can see the skin and then you have like your can read it. Something that can read the bacteria bubbles on your skin.

Savannah Boda (42:15)

That's gonna be so exciting. I can't wait for that.

Tyler Jacoby (42:19)

Is that like a 23andMe where we have to, like, send them off to a lab or, like, we can do it.

Isabelle Vitaly (42:23)

You will have to send it off to lab. Yeah.

Savannah Boda (42:25)

Okay, cool. Hey, that's amazing.

Isabelle Vitaly (42:28)

But I think it'll be so cool too, to, like, get that data and, like, start seeing trends and learning about the microbiome too.

Savannah Boda (42:34)

And I think just like biome care in general, you know, has been such a big topic in our industry, but I think it's now kind of trickling down to the consumer level where people are like, oh, my microbiome. Like, what is that? Why does this matter? Barrier repair, all of that. That is so amazing. So I'm trying to think what other questions I have. Do you have any that you can think of? I know I have some.

Tyler Jacoby (42:58)

I just wanted to know how a spore worked.

Isabelle Vitaly (43:02)

Did I answer the question?

Tyler Jacoby (43:03)

I did, Absolutely.

Savannah Boda (43:05)

Yeah.

Tyler Jacoby (43:05)

No, Yeah. I, I, I guess my, my two main things were how does it interact with the skin? And, like, do we already have it? Like, you know, like, how some of the others.

Savannah Boda (43:15)

Yeah, yeah. Like, is it already, like, a resident?

Tyler Jacoby (43:17)

Yeah, she's not, it's not. She's moving.

Savannah Boda (43:19)

She's a messenger bird.

Tyler Jacoby (43:20)

Yeah. She's vacationing on the skin.

Savannah Boda (43:22)

I love that. Okay, so back bar size microbiome test. Okay, well, you just tell us, tell us fun facts about you. Tell us, you know, what you hope people take away from this episode, what they learn about you and your company. I mean, anything. The world is your oyster. The stage is yours.

Isabelle Vitaly (43:40)

Oh, my gosh. Wow. I just want them to know, first of all, like, everyone should be using this. This is like, you take a probiotic for your gut. Like, everyone is like, on that the skin is just as important. Like, so, so many times we say that the skin is the largest organ, but, like, do we really understand what that means? Like, when we have acne or when we have an inflammatory condition that is your largest organ constantly inflamed. It doesn't take a break at night, it doesn't take a break during the day. It is constantly inflamed. Any other organ of the body that's constantly inflamed, we're getting that checked out. We're getting that Figured out. Right. And, like, on the scan, we're just like, oh, my God, like, this. So annoying. And it's like, no, it's like, actually a problem.

Savannah Boda (44:19)

Yeah.

Isabelle Vitaly (44:20)

Really get that dialed in. It's not vain. It's not vanity. It's your health. This is your largest organ. Right.

Savannah Boda (44:27)

Care is healthcare.

Isabelle Vitaly (44:28)

Really taxing on the body to have that kind of inflammation. So I just want people to understand, like, taking care of your skin is not vain. It is not vanity. It is a huge, crucial part of your health. And there's so many indications on the skin that drive internal stressors in the body. Like, it's not just that your skin is reflecting what's going on on the inside. It is truly driving what's going on on the inside. So there's a study, it's called the Baltimore Longitudinal Study of Aging, actually. And it followed this group of people throughout their life. So, like, starting young to old. And so it's not like a regular cohorted study where it's like they're comp a group of young people to a group of old people. They really followed these people to see how they aged. And what they found in the study unequivocally was that the health of their skin was an independent risk factor for whether or not they would develop a chronic disease somewhere else in their body.

Savannah Boda (45:19)

Whoa.

Isabelle Vitaly (45:20)

So an independent risk factor. Regardless of any other lifestyle things, the health of their skin alone was able to determine whether or not they had this.

Savannah Boda (45:30)

So I guess we will never die.

Isabelle Vitaly (45:32)

Yeah. You guys are.

Tyler Jacoby (45:33)

I don't know. I'm super acne prone. That scares me.

Savannah Boda (45:39)

We're basically immortal.

Isabelle Vitaly (45:41)

Yeah, right.

Savannah Boda (45:42)

That's amazing. That is such a cool study. What was it called again?

Isabelle Vitaly (45:46)

The Baltimore Longitudinal Study of Aging.

Savannah Boda (45:49)

Hey, I'm gonna have to look into that. That's actually really, really cool.

Isabelle Vitaly (45:52)

I can send it to you. It's really cool. And they're even doing new studies now, too, where they're linking, like, certain. Like, I think it's either yeast overgrowth or fungi overgrowth to Alzheimer's. Wow. Because on the nose, you're breathing those spores in, and it's affecting your brain. Like, more and more things are going to start coming out like this. And people need to realize, like, you need to treat your skin well, not just how it looks like it's truly a huge piece of health. And that's really what we're going after with civ is just improving the health of the skin and overall health of the skin.

Savannah Boda (46:26)

I love that. And do you know what Pop quiz. Skin iv.

Tyler Jacoby (46:35)

Oh.

Savannah Boda (46:35)

Was what it was originally called, but then also you could say spores. Isabel. And then your last name is. Vital.

Isabelle Vitaly (46:43)

Vitaly.

Savannah Boda (46:44)

Yeah, Vitaly. So it also could be like her name, her initials.

Tyler Jacoby (46:47)

I love that.

Isabelle Vitaly (46:48)

Skin.

Tyler Jacoby (46:49)

Ib.

Savannah Boda (46:49)

Yeah. Because it was a. It was Skin iv. Right. And then you just made it sieve. I love the name. It's catchy. It's short, it's easy.

Tyler Jacoby (46:57)

I mean.

Isabelle Vitaly (46:58)

Yeah, we liked it too.

Savannah Boda (46:59)

We.

Isabelle Vitaly (46:59)

And there's like, you know, things that you can be like, oh, like, save your skin. Or like, oh.

Savannah Boda (47:06)

My God.

Isabelle Vitaly (47:08)

Yeah. Save your best life.

Savannah Boda (47:09)

I love that Savior. Save your best skin. Honestly.

Isabelle Vitaly (47:14)

Yeah.

Savannah Boda (47:15)

No, that's amazing. So for estheticians that are listening and want to carry a wholesale account, what's the best way for them to get in contact?

Isabelle Vitaly (47:23)

Yeah, so they can absolutely sign up on the website. So civcare.com and then there's a For Professionals tab, so you can sign up through there and you'll get a welcome email and an onboarding call with me. You can also follow us on Instagram and DM us on Instagram. That was one actually really great piece of business advice I got from somebody was to, like, greet all of your Instagram followers and to really engage with them because Instagram is such a fantastic tool.

Savannah Boda (47:52)

Yeah.

Isabelle Vitaly (47:53)

And so that's brought me a lot of really, really great connections over there. Because it's not then passive. It's like you're really, like, actively trying to connect with them. So that was great. That really changed our business a lot, too.

Savannah Boda (48:04)

I love that. And I was just gonna ask. We have an md, obviously, but for the estheticians that don't. Are you able to carry this product with Automatical director? Yeah. Amazing.

Isabelle Vitaly (48:14)

Open to all.

Savannah Boda (48:15)

And then what else was I going to ask? It was such an important question and of course I'm going to forget it. Like a dumbass. Oh, are you guys working on getting patented delivery systems or anything? Are you trying to get Civ patented? That was something I wanted to ask.

Isabelle Vitaly (48:31)

We are. We are working on kind of protecting what we've created.

Savannah Boda (48:35)

As you should. You need to please.

Isabelle Vitaly (48:38)

Yeah, totally. So it's in the works.

Savannah Boda (48:41)

I've heard it's a bitch Pat or something. So all the prayers and love towards you, but if anyone can do it, you can do it.

Isabelle Vitaly (48:48)

Thank you.

Savannah Boda (48:49)

We'll be sending you lots of coffee and flowers. And then what else was I gonna ask? Oh, and then for clients and followers, we carry SIV on our website. So if you want to get it, you need it siv your best life. I'm so excited for everyone to try this. And, I mean, you guys, it's something that can be virtually used on every single skin concern, whether it's, like she said, bug bites, acne, fungal acne, folliculitis, eczema, psoriasis, dermatitis. I mean, so good, especially just for irritation, dryness. I mean, it is such a game changer. And again, such a good price point. Like, thank you for making it affordable and accessible for so many. That is huge. Like, you could easily be charging, like, 600 for this. And so the ethics that you have and carry and the results that you carry are why you are such an amazing partner. And I just adore you and what you're doing. And we are your biggest supporters. We're excited to see you grow and just thankful we can be along for the ride and to help you any way we can.

Isabelle Vitaly (49:49)

Thank you so much. That really means a lot. And, yeah, I mean, I wanted to keep it accessible because I really think that everyone should be using it, and it's just going to benefit everybody. And thank you guys for the work that you've been doing for now with us, for us, everything, and bringing it to a whole new audience of people who need it. And the before and after is I'm like, I'm dying. Literally, my heart, like, explodes. I'm like, oh, my God.

Savannah Boda (50:12)

I know. I cannot even imagine that feeling. Like, it's like watching your baby, like, become the president, right? Like, I guess how I'd imagine it would feel like to create a product that's, like, doing all that. It'd be like watching Cyrus become, like, the President of the United States. That's amazing. And shout out to Jen as well. She with her before and after that one of her clients sent her was the reason I was like, okay, yeah, I'm gonna get over my fear of biome products and give this one a shot. And I'm so glad I did. And I learned a big lesson in this that, you know, sometimes when you try certain things, like, again, this is very different than what I was referring to that we used in the past. Very, very different the way it works. Very different ingredients, all that, but similar realm of skincare. You put it, like, if you put, like, you know, yeah, microbiome thing, don't let one bad experience shut you off, because you might be missing out on something amazing. And that's something amazing with Civ.

Tyler Jacoby (51:07)

One door closes, another opens always.

Savannah Boda (51:10)

And I 100% back this.

Tyler Jacoby (51:12)

Yes.

Savannah Boda (51:15)

All right.

Tyler Jacoby (51:15)

This message is approved.

Savannah Boda (51:16)

This message is approved by Samana Boda. Any closing thoughts or anything? You want to leave us with something you want someone to know? Anything you know?

Isabelle Vitaly (51:27)

Thank you, guys. Everyone should be using this. And tiny bacteria. Big deal.

Savannah Boda (51:32)

I love it. And that's what's right behind her, which I think is so cute.

Tyler Jacoby (51:34)

I love that.

Savannah Boda (51:35)

I love it. Thank you so much. It was so good to see you and we look forward to seeing you soon.

Isabelle Vitaly (51:41)

Yeah.

Savannah Boda (51:42)

Thank you.

Tyler Jacoby (51:44)

Thanks for listening, besties. Have a wonderful rest of your week. We'll see you next time.

Savannah Boda (51:48)

We'll see you next Monday. Bye, guys.