Three new GLP-1 studies, why every food is suddenly "high protein," the Bethenny Frankel shoe drama blowing up Instagram, and why I'm on a ketamine table as you listen.

Three new studies just shifted the GLP-1 conversation, and not in the direction women have been hearing about. Chalene digs into what's actually happening to muscle and bone density, why the rebound after coming off matters more than anyone's talking about, and the three questions every woman on Ozempic, Wegovy, Mounjaro, or Zepbound should bring to her next doctor's appointment.

She also gets into why every grocery aisle suddenly screams "high protein," and why this whole moment is starting to feel suspiciously like the Snackwell cookie era. There's a simple protein target that works without tracking macros, and Chalene walks through how she's using it.

Then she breaks down the Bethenny Frankel shoe drama that took over Instagram this week. What the shoe brand founder got wrong, what Bethenny got wrong, and the rules of brand partnerships that almost nobody outside the influencer world understands.

Finally, a personal update. As you're listening to this, Chalene is on the table for another medically supervised ketamine treatment with Dr. Andrew Levinson. She shares why she went back for a third session, what the last journey taught her about control, and who this kind of work is really for.

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🤓 Studies:

March 2026 — Weight loss with GLP-1 medicines does not result in a disproportionate loss of muscle mass or function in obese mice and humans

https://pubmed.ncbi.nlm.nih.gov/41850248/

March 2026 — Studies explore: GLP-1 receptor agonist use and its impact on long-term musculoskeletal health

https://aaos-annualmeeting-presskit.org/2026/research-news/studies-explore-glp-1-receptor-agonist-use-and-its-impact-on-long-term-musculoskeletal-health/

May 2026 — Muscle atrophy associated with glucagon-like Peptide-1 receptor agonists: A population-based observational study

https://www.sciencedirect.com/science/article/pii/S0261561426000476

April 2026 — GLP-1 therapies and hair loss: A systematic review of current evidence and implications for counseling

https://pubmed.ncbi.nlm.nih.gov/41998799/

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