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Dr. Axe
Ryan Reynolds here from Mint Mobile. With the price of just about everything going up, we thought we'd bring our prices down. So to help us, we brought in a reverse auctioneer, which is apparently a thing. Mint Mobile Unlimited premium wireless. Better get 30, 30. Better get 30, better get 20, 20, 20. Better get 20, 20. Everybody get 15, 15, 15, 15. Just 15 bucks a month.
Danielle
Sold.
Dr. Axe
Give it a try@mintmobile.com Switch upfront payment.
Danielle
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Dr. Axe
To $15 per month.
Danielle
Required new customer offer for first three months only.
Dr. Axe
Speed slow after 35 gigabytes of network's busy.
Danielle
Taxes and fees extra see mintmobile.com Pore clogging ingredients are wrecking people's skin. And it's the most common fillers that every company is using for skin care, hair care and makeup. So most moisturizers out there have pore clogging ingredients. And when I say most in my professional experience, I would say like 97% of them.
Dr. Axe
One of the trends online right now on social media is doing beef tallow.
Danielle
Gross. We do not like this trend.
Dr. Axe
What do both of you eat typically for breakfast, lunch and dinner to optimize your skin health?
Danielle
So we're big proponents of maximizing digestion. Apple cider vinegar before meals, hot water with lemon before meals, snacks. Sitting and chewing the food thoroughly makes a huge difference in your skin.
Kaylee
I didn't understand what birth control was actually doing to my body for 10 years. My crow's feet are smoother than they were when I was 16, 17, 18 years old. What people need to know about Botox is that.
Dr. Axe
Hey, everyone, Dr. Axe here. Welcome to the show. Today I've got an incredible episode. We're going to be talking about healing your skin and looking and feeling younger. If you want to learn how to reverse acne, if you want to learn how to start to reverse and heal acne, scarring, overcome rosacea, and Overall just look 20 years younger. I've brought in two of the world's leading experts in skin health, Danielle and Kaylee. And and they are the founders of Clear Stem. They're experts in stem cells for your skin, reversing acne and overall longevity and anti aging in the skin. Danielle Kayleigh, welcome to the show.
Kaylee
Thank you for having us.
Dr. Axe
All right, well, I know that acne is something that people don't just suffer from in junior high and high school.
Danielle
Not at all.
Dr. Axe
It's something that can affect women all the way up to menopause. Men deal with it as well. What really sort of got you Guys focused on creating a skincare company and helping starting your clinic and helping people specifically deal with acne.
Danielle
Well, we're both very acne prone, and that's really important. Don't take advice if you're struggling with acne. You should be getting advice from people that have gone through it and that are still kind of prone to it. That way, they're, like, in it with you. So Kaylee and I were both in the struggle deep acne, there's a genetic component, but then there's environmental and lifestyle factors that determine how bad it gets and how long it sticks around, right? So I have a grade four cystic acne on both sides of my family. Like, I never stood a chance. So I was studying genetics, cellular biology, and immunology all through school and wanted to go into medicine. But at the time, when I went to college, my acne flared like crazy. Like, cystic acne. Face, neck, chest, back, back of thighs. Like, it was absolutely terrible. So I did the whole gamut of being on antibiotics and then stronger antibiotics and then birth control, and then a different birth control. Spironolactone multiple times, Accutane three times, and it came back every time. So this fast forward to I'm 30 now. The third round of Accutane has completely failed. MACNE came right back within a couple months, and I was like, screw this. I'll have to figure it out myself. I started looking for classes to just learn about the skin, and you couldn't really take any professional classes unless you were an esthetician or in school. So I was like, all right, I'll enroll in school. And I was in the corporate world doing consulting, something totally unrelated. But when I got to esthetician school, I saw that treating acne was like the medical profession I'd always dreamed of but didn't know existed, because it had never occurred to me to become an esthetician. So I started San Diego Acne Clinic about a year after that. After learning from all the top kind of people in San Diego and being a sponge, I started San Diego Acne Clinic. And I met Kaylee as a patient.
Dr. Axe
Oh, wow. Incredible. And then your background's in holistic nutrition.
Kaylee
Yes. I've always been so passionate about what you put in your body and the effects that it has. I was a student athlete all growing up. And I very quickly noticed, even at the age of 13, what I put in my body is how I would perform on the track field. And I was a gymnast, too. And so I learned that so quickly, and so Fast Forward to my mid-20s. I decided to get off of birth control. I'd been on birth control for 10 years. I was put on it at 14 for acne and mood swings. I just wish I would have, like, gone to therapy. I had divorced parents, I had mood swings, and so that's why I was put on birth control. So when I hit my mid-20s, I didn't want to be reliant on any medication. So I got off and my whole body seemed to backfire on me. I didn't understand what birth control is actually doing to my body for 10 years and how it could potentially have a repercussion getting off of it without supporting my body in the correct way. We now educate about that so much when people want to transition off of birth control, how to properly do it to potentially avoid a lot of the repercussions of breaking out. But I get off birth control and my whole skin just freaks out. I dealt with typical teenager acne, but nothing super aggressive. This was aggressive cystic acne.
Dr. Axe
Yeah. I would love to talk about sort of the hormonal connection here and the gut microbiome connection because I've, you know, ran a functional medicine clinic for years and taken care of a lot of women who. I mean, one of the biggest surprises that I had when I first got into practice was how many women were on birth control. I mean, it is absolutely staggering. And when you look at the statistics, it's incredibly high. The other thing that most women don't realize as they get on birth control is the nutritional deficiencies it causes.
Kaylee
No one tells you almost every single.
Dr. Axe
B vitamin, magnesium, what it does in shifting the good and bad bacteria in the gut microbiome. And so most women, when they get off it, of course, we know estrogen almost acts like fertilizer for microbes in the gut, but when you get off of it, what estrogen does and how that causes microbial overgrowth. And then, of course, yeast is one of the biggest issues. But I'd love to hear from you guys in particular. What are some of the things you do, maybe dietarily and even topically, to help women as they're transitioning off of birth control?
Kaylee
When you get off of birth control, the most important areas to support is your lymphatic system and your ability, ability to detox, AKA sweating and bowel movement. So we first recommend lifestyle shifts. Warm water with lemon in the morning. If you can do jumping jacks or rebounding or go for a walk and really get that lymphatic system Moving, making sure you have the ability to sweat, whether that's through sauna, working out, going out. We're in Nashville, going out in the humidity and going for a long walk, that can also do it. But also making sure that you're having one to three bowel movements a day. Because if we're not excreting all of that buildup in our body, it's going to come out somehow. And if it's not coming out through bowels and sweat, it's going to attempt to come out through the skin. And so those are the first ways we have people support their body. Once those are in check, then we discuss the supplemental supplement supports. But we don't want people going too hard on supplements when their detox pathways are not open first. The first supplement we do recommend is our Mind Body Skin supplement. We did formulate that specifically for dealing with hormonal breakouts. And it can be an amazing transitional support. Getting off birth control and after.
Dr. Axe
And what are some of the nutrients you look to make sure people are getting as they're getting off of birth control?
Kaylee
Definitely supporting with their B vitamins. But it's important to not overdo it with B12. A lot of people will just reach right for a B complex which will have so much B12 in it. And B12 is actually known to trigger acne. So that's a big one that we actually have people take a of lot look at when they're struggling with acne. We have them make sure they're not overdoing it on B12. But we love panathenic acid. We love like all the B other B complexes. Another one to support is really overall your gut, it doesn't have to be through probiotics. Probiotics are amazing. But making sure that you're eating gut friendly foods and making sure you're not overdoing it with the processed foods that are going to continue to throw off your gut. Microbiome.
Dr. Axe
Yeah, it's really good. You know, one of the things I found is really good for again, constipation is a big thing with a lot of people. And I'll have them do a lot of fiber from apples and pumpkin. Those, those foods tend to be really good for most people, even with autoimmune disease. And then doing some good, you know, collagen or bone broth, protein, those sort of products.
Kaylee
Love protein.
Danielle
Protein and a green apple.
Dr. Axe
There you go.
Danielle
And we love apple cider vinegar too.
Dr. Axe
Yes.
Danielle
But we actually have an apple cider vinegar tincture that kind of like the taste is really mild, but it still, like, hits you. And ACV in the morning can get you to poop right away. Like, it's great.
Dr. Axe
Yeah, yeah. You know, so some of the flavors, people don't realize how that impacts their, you know, their gut, you know, sour and bitter specifically are really sour. There you go. Yeah, I love that. Well, so as you're saying. And by the way, the things that birth control really throws off, B vitamins are really at the top of the list, you know, that you hit on people need bacteria or good bacteria, or feeding the good bacteria is another big thing. When you look at some of the other things. So there's obviously some vitamin, mineral, nutritional deficiencies that you try and address with patients. And then the other thing you mentioned is really getting those lymphatics moving, rebounding, walking, infrared, sauna. All good things to get things flowing. What are some. Maybe some of the herbals or other compounds you like, both in internally. But then I'd also love to hear from you, what are some of the things you really love and recommend topically?
Danielle
So some of the vitamins and nutrients that you want to have extremely healthy skin and help your hormones kind of balance themselves. Dim is extremely helpful for most people. The right amount of dim, if you take too much, it can kind of back. Just like with anything, right. You want to have the right amount. So dim is extremely helpful, especially for estrogen dominance, which is rampant. And then also having 5 HTP to manage stress. We really, really like 5 HTP and then anything to support your liver and your lymph, that is your dandelion, your echinacea, that whole suite of, like, liver and lymph supporting nutrients that helps your skin directly and it helps your hormones directly. We're big proponents of loving the liver and that will in turn love your skin.
Dr. Axe
Yeah, yeah. There is so much the liver does that people don't realize. You know, I mean, the liver is one of the biggest hormone balancers in the entire body, especially estrogen. You get, as you mentioned, we should.
Danielle
Have a holiday in this country that's all about the liver.
Dr. Axe
All about the liver.
Kaylee
I love that.
Dr. Axe
Yeah. You know, I mean, there's obviously heart Month, there's cancer. I mean, there's all kinds of things, really.
Kaylee
You should have liver Month. It's so overlooked because birth control is incredibly taxing on the liver. And so anything we can do, even when you're. If someone who's listening is still on birth control and you know at some point you need to get off of it, Support your liver now because birth control is so taxing on your liver. If you can just bring a lot of those more herbal supplements that Danielle listed off. Also you can add in spearmint tea. That's a really good one to add in for hormonal support and liver support as well. Just get that liver supported while you're on birth control and also transitioning off.
Dr. Axe
Yeah. One of the things in Chinese medicine that causes breakouts is they'll call it liver fire is the actual terminology they'll use. And spearm, as you mentioned. And then along with a lot of the bitter herbs, whether it's burdock or milk thistle or dandelion, those are all things that start to clear that liver heat and reduce the inflammation that the liver is dealing with. So I love that. I think those are just phenomenal recommendations. One of the other things I really liked about the skincare you all have created and I was saying this earlier, my, my wife is. Of the two of us by far, I mean she does, I mean ten times an understatement. She has done so much to care for her skin. My wife has beautiful skin and she does a lot. In fact, sometimes I get a little bit annoyed because I'm like, how long is she going to do her skincare routine? It is so long.
Danielle
Just long enough to sleep for an hour and wake up and start her morning routine.
Dr. Axe
Exactly. And I'm just like, you know, this thing is like, I don't know how long, but it feels like it's a long time. 15 minutes, 20 minutes maybe. It's longer, it's a long, you know. And so my wife has done everything over the years from. She's done this herself, she's done her own, I think they're called vampire facials. Where she kind of does like this.
Kaylee
Micro needling.
Dr. Axe
Yeah, micro needling. And then she, we had a friend of ours draw her blood. She made it into prp. So then she'll do this micro needling and stuff herself at home. She then has this jade roller and she does like gua sha on herself.
Danielle
She's doing everything right.
Dr. Axe
Yeah, she does all kinds of things and then spends a lot on like the, you know, the skin care. But she started doing when she was 25 and like I have a mother in law who's very similar and she's 61 and she looks like she's, you know, 20 years younger than she is. So I think obviously one of the things I've noticed is there's a lot of people I'd Say especially millennials who, where maybe they're the baby boomers or the Gen Xers. They didn't start doing their skincare routines until their 40s or even 60s and.
Danielle
They were out sunning. That was the generation that was out like putting like baby oil on their.
Kaylee
Skin and holding the towel to reflect the sun even more.
Dr. Axe
Yes. And so they've done so much of that. Whereas I feel like a lot of millennials have been more conscious of starting their skincare routines in their even late 20s, you know.
Danielle
Yeah. And the education on sunscreen has been prominent enough to where like everyone knows you should be wearing sunscreen and luckily it's most people are aware now that you should be using a mineral sunscreen, preferably zinc based, so that it's anti inflammatory and creates a bit of a shield and won't disrupt your hormones. So yeah, that's the number one tip for anyone. Whether it's acne, acne, scars, anti aging, a zinc based sunscreen is the thing that makes everything else work.
Dr. Axe
Yeah.
Kaylee
We are also big fans. Sunscreen, mineral base, face, neck and chest. But we actually love to leave the rest of our body free of sunscreen. It's different if you're going to the beach in the high UV hours. It's super different. But we shouldn't be aggressively outside in the height of the UV hours anyways. Like focus on morning and evening to get your sunlight. But we like to leave the rest of our body free so we can actually absorb and metabolize vitamin D. I'm.
Dr. Axe
So glad you're saying this because I've seen other people that are, you know, whether it's dermatologists or nutritionists or estheticians who have said, you know, no sun anytime, cover your entire body, love the.
Danielle
Sun, use your vitamin D. And of course it's important for the liver, for sappiness.
Kaylee
Yeah, yeah.
Danielle
And your circadian cycle. Yeah.
Kaylee
We need the sun so much. We just like to perfect protect our face, neck and chest. Get a hat on, put a zinc based SPF on, but leave everything else exposed.
Dr. Axe
I think that's, that's good, good balanced advice.
Danielle
Yeah. And people are like, no, don't wear sunscreen at all. You need your, you need the UVB to convert to vitamin D. Like of course that's true, but it's all about surface area. When you're having that conversation, get, you know, protect your face, neck and chest. But then I'm always wearing the shirt that covers my chest, but it's like a crop top. So I'm getting My, like, I'm getting my vitamin D through, like, tummy and back access. Like, that's my strateg. So, yeah, like legs, torso, back, like arms. Like, that's the surface area that you want to get your vitamin D conversion from. It does not need to come from your face, neck, or your precious chest. Yeah.
Dr. Axe
You know, I think a lot of people for years thought that. Of course, I never thought this. Most people that are holistic nutritionists or in the space never thought this. But the sun causes cancer. And the reality is, even when you look at the research is that people that get more sun, if they do it in a balanced way over time, they have way less skin cancer. It's the people that go out and they just burn themselves. I mean, getting burnt is one of the single worst things you could do for skin cancer, for your skin.
Kaylee
In the craze of the tanning beds for so long, that's burning your skin, but you're getting no nutritional value from the sun. And so I feel like the tanning bed craze happened and burning your skin and so. And then, of course, there's a lot of internal causes of skin cancer as well that have gotten completely overlooked and more of a modern dermatology route.
Dr. Axe
I love that. You know, one of my favorite sources of wisdom for health and nutrition is the Bible. And I love song of Songs, love the Book of Esther. Those are two in particular that talk somewhat about essential oils, about skincare routine. And I think it's referenced, you know, Esther went through like six months of beauty treatment before she got married, and they referenced essential oils there. And one of the things that I noticed that you guys have done and recommended when you're working with patients, and I've seen, you know, whether you guys are speaking on podcasts or lecturing or just even in your own skin care products you formulated, you guys include a lot of amazing herbals. One of the things that I really like in skincare, and I notice my skin reacts well too, is things that are more aloe based rather than oil based. I've noticed if I use anything that's really oily, my skin doesn't do well, versus if I do things that are more like aloe or honey or. I mean, essential oils are fine, but actual oil. Oil doesn't do well with.
Danielle
Yeah, it would just sit on top of your skin.
Dr. Axe
Exactly. Yeah, it doesn't do well at all. But again, I love that you guys. The number one ingredient I see in all your products is aloe. And then there's some Other amazing compounds that are like stem cells and other things. There's all frankincense, of course, which again is probably the most widely referenced essential oil of the Bible. Talk to me about how you picked some of the different herbs you've picked for skin care and maybe some other different effects on the body.
Danielle
Well, it wasn't from the Bible, although I love that. And I want to learn more about what the Bible says about beauty treatments. But it was from just traditional Chinese medicine and just really I have a formulation kind of background. We formulated cell renew. That was the first thing I formulated. It was because my clinic patients, I had a lot of, you know, darker skin clinic patients. And the scarring would be the biggest problem. Even like a tiny little breakout would leave like a six month scar. And the things that you would do to get rid of scars generally like an aggressive peel or you know, some sort of laser treatment, like even that could scar them. So I'm like, we need to calm the skin down and heal it from a different way. The skin has to be calm in order for the scars to regenerate. We also need growth factors. We can tell the collagen that it's time to regrow and give it what it needs. And we also need some herbs that can kind of help fight that fire and those that have that cooling effect on the surface of the skin and somewhat balance the hormonal activity in the pore if we can. So that's where like willow herb and saw palmetto come in. And then there's turmeric for inflammation, reishi for adaptogen. So it was really just thought out for those three things that I wanted the product to do, to balance, to soothe, you know, maybe cool a little bit and then to just regrow the skin. So that's what's different about our line. Most acne products dry your skin out and cause accelerated aging. If your skin is chronically dry and your barrier is damaged, you're getting UV damage faster and you're going to wrinkle faster. Basically most acne products age you faster, but then most anti aging products break you out because of the filler agents that all the companies use. So our line is right in the middle. It's anti acne via anti inflammation and then it's also anti aging with all the growth factors. So it really people come to us for the acne, but their skin just gets better and better and then they're aging really well, like better than they have with any of their other anti aging products. So that's why they stay with us.
Dr. Axe
Yeah, I would say one of the other things again, I really loved going through the. I'm a formulator as well, more for supplements than for skin care. But I didn't notice a lot of the ingredients in understanding why those can be so impactful for skin care. And I think I saw some of the TCM herbs. I also saw a lot of the Ayurvedic you mentioned turmeric. The Frankincense really is 10. I mean that's Middle Eastern, but also Ayurvedic there a lot too. And then what was the other one I saw? I saw some rose in there. You know, a lot of those floral oils are just amazing for calming the skin, you know. Yeah.
Danielle
We chose the low sensitivity essential oils that have like a really good benefit. Using a ton of essential oils, if they're not properly diluted in the right ratio of the formula can be irritating to some people. But in small amounts in the right formula, they're fantastic.
Dr. Axe
Now talk about some of the benefits of stem cells because I think that's where you guys have really shined and really had a great amount of your focus on how to heal acne, how to create younger looking skin is via focusing on supporting the body's own stem cell production and protecting stem cells. What led you all to really focusing on that stem cell piece of skin health?
Danielle
Well, it's the epidermal growth factor, the EGF kind of suite of ingredients. And that can include different peptides, it can include stem cells. There's also really good data behind plant stem cells too. So we use a lot of these different types of epidermal growth factors because you don't want to load all of them into one product. You kind of want them throughout your suite of products, if you will. So our moisturizer has plant stem cells and bakuchiol, which helps stimulate collagen similar to retinol but without the irritation that retinol can cause. But then our serums will have like peptides. Like we have a serum that has three different peptides in it. And then there's plant stem cells and other types of stem cells in all of it. So the skin is getting everything it needs at every turn. And it's, I mean stem cells are the start of, they're the start of everything. So you want to make sure that you're nourishing them and protecting them. And then all of our education is low key about how to preserve them in your own body too. Like reducing sugar, reducing inflammation, helping your gut health, your liver all of that. So it really is like 360 protection of those core things that we need in order to age. Well.
Kaylee
Another reason why we found it so important is a lot of people, when they're tackling acne, as Danielle mentioned, it's focused on products that are just aggressively drying out the skin, which then can create further and new damage and leading to scars and longer lasting scars. So when you can actually help the breakouts and the scar damage at the same time, and doing that through the epidermal growth factors, through the stem cells, through the peptides, you're doing both at the same time. You're helping the acne, and you're halting a major scar from forming. And then if a scar does start to form, you're tackling it even faster. So it's tackling both healing processes at the same time. So people aren't left with pigmentation and scar damage for six months after they cure their acne, after they heal their acne or their breakout. So that's why it's also so important and then ends. It also adds that longevity skin health aspect to it, where you're not aging as fast or it doesn't appear to be aging as fast.
Dr. Axe
You know, I love that your mindset's very much like, we need to get to the root of why this is an issue in the first place. And I think that, you know, when you guys talk about people going from, let's say, having oily skin that's breaking out than over drying, a lot of times that's done via. People are trying to change it via a medication or maybe a conventional skin care product. It's almost like sometimes it's like, okay, I'm gonna try and replace one bad habit with another or one bad product with another. It's like, I'm gonna switch from smoking to drinking soda. It's like, well, this is not fixing the actual problem here at all. And I love. And it's all about environment, you know, changing the environment there as much as you possibly can. It's like, hey, if you want a plant to grow, a beautiful. Chelsea, my wife and I, we just planted, did a big garden this year. And so, you know, we were very strategic in terms of the soil we bought. We were doing this mixture of. Of certain types of worms with certain types of mushrooms and fungus, certain types of pima, you know, like, so I did a lot of research on what is the ideal soil for a raspberry bush to grow in versus, you know, zucchini versus tomato versus, you know other things, but it's very similar and it's different for everybody, you know, different for everyone's skin. Whereas I know some people have naturally more oily skin, some people have more dry skin. Well, are there any recommendations you have for people based on their skin type?
Danielle
Yes, but there's a couple that apply to everyone and I'd love to share with those. So people are doing all this, you know, amazing stuff for their skin, but if they're using hot water to cleanse their face or standing in a hot shower and letting that hot shower water be on their face, they're destroying their skin. That is the thing that will keep you oily and dehydrated at the same time. You'll be red and you won't know why your rosacea will flare. Hot water is ruining everyone's skin. And the thing is, is it basically halts the healing response that you're trying to get when you go and do expensive treatments. Like for example, you go do a high heat laser or you do even just microneedling when there is no heat and you're going home and using hot water in the shower, destroying your skin and destroying the barrier. So that's causing people a lot of issues. And nobody benefits from doing hot water on their skin. So that's one. But then based on skin type, I mean, it really depends on if you identify as being oilier. You're going to do better with hyaluronic, hyaluronic based things, aloe based things, and those can be good for everyone too. But it's all about how you layer. So everyone's going to benefit from a hyaluronic. Everyone's generally going to benefit from an aloe blend. So doing thinnest to thickest in your routine and then figuring out what ingredients work best for your skin. Like if you're combating redness, you're going to want some cooling herbs. You're going to want to avoid things that have like any sort of like pepper in them or anything like that, or things that feel caustic, you know. So it's just about listening to your skin and layering thinnest to thickest with really good ingredients and calming ingredients help everyone too. So really looking for those like anti inflammatory things, like a little bit of turmeric or some willow herb that benefits everyone.
Dr. Axe
Yeah. And I've noticed for instance, like my skin does really well with the aloe, with the things that are very cooling, aloe, rose hyaluronic acid, all the things you're mentioning, there's Whereas my mother in law, she's through menopause or in menopause, she does well with the oil or doing well with the things that are more sort of moisturizing in that way too. So obviously there's a difference in ages. Any thoughts on that as well?
Danielle
Yeah, I mean, mature skin tends to be a little bit more dry, especially when testosterone decreases. Testosterone is kind of like what fires the oil production. That's why guys like teenage boys tend to be really, really oily and then it calms down. But women, especially after they go through menopause, their sk is notoriously dry. So it just wants to drink up everything. I still think layering thinnest to thickest with like a serum and then finishing it with an oil, that's how you seal it in. But not all oils are the same either. So some oils like coconut oil are pretty thick and they have a comedogenic rating of 5, which means it's like the highest comedogenesis rating, very likely to break you out if you're acne prone. Then there's other oils that have a comedogenic rating of zero. So anyone can use that.
Dr. Axe
And what are those?
Danielle
Like what would be hemp oil, which is one of my favorites. I get massaged with that. So organic cold pressed hemp seed oil is fantastic. And then jojoba oil can be a 0 or a 1. It's usually safe for most people. Rosehip oil, amazing. Argan oil is generally safe for most people. And then safflower and sunflower. And then ours is actually watermelon seed oil which is organic and cold pressed. But it has comedogenic rating of zero. And we actually blended it with sodium hyaluronate. So it's like multiple layers of hydration. Because a straight up oil, it's not the best for everyone. You want a nice blend or you want it to be on top of a thinner molecule like a sodium hyaluronate, hyaluronic acid.
Dr. Axe
So one of the things that surprises some people is you can have too much of a good thing. And you know, today we're living in this world where vitamins and supplements are very popular. I do quite a few vitamins and supplements myself, but I'm actually pretty conscious. Anytime I'm buying vitamin and supplement brands, I'm buying things that are more whole food based and that tends to actually be lower dosages and more absorbable. You guys had mentioned this earlier, vitamin B12. High doses can actually cause breakouts and actually cause acne. It Makes sense to me because your liver is having to deal with a lot of that. So every time you over consume something, vitamin C, that's going to be your kidneys. Right. So if you're over consuming something, there's an organ that has to deal with that stress. Walk me through, are there any other vitamins, nutrients outside of vitamin B12 that we can have too much of that that will actually cause breakouts or skin issues?
Danielle
We love this question. So, so many women are getting high quality supplements. They're just taking too much of things and it's not really matching what their deficiencies are. And then they get hormonal acne and then they go get put on spironolactone, but it's really being caused by their vitamins. So vitamin B12 is another one. And I and experienced personally that levels of like over 500% RDV can be problematic. And it'll get you in your neck, right along your jaw. So it is, it looks like hormonal acne, but it's generally right along the jaw. I see that all the time. And when B12 shots were a thing, people would come in like my phone was blowing up at the clinic when that became a thing. So that's number one. And then excess vitamin D, believe it or not, most people are deficient in vitamin D. We do not want to be that deficient. But if you think, if you get told you're deficient and then you go and get, you know, say it's like 800% RDV and there's no K2 and you just start taking that, and you start taking that for a year, two years, three years, and you don't get your levels rechecked because most people don't. That's when you get the surplus because it's fat soluble and it can spike testosterone for some people, vitamin D is also a hormone. It throws off other things. If you're taking way too much of it and it's not being metabolized properly, that'll get you in the goatee area. So excess vitamin D, I see you get people right where they're, where they'd have a goatee.
Dr. Axe
So what's so interesting is one, you know, if you ever looked at Ayurvedic or Chinese medicine, face mapping, I mean these are all areas like, you know, liver here and then you've got things like in terms of, I think like kidney, stomach, urinary tract in this area and then up here, this is more lung channel.
Danielle
Yeah.
Dr. Axe
And so it's because you're overwhelming the organ with too much, even if it's a good thing.
Danielle
Too much of a good thing.
Dr. Axe
Yeah. And the thing with vitamin D as your point, you have to have vitamin K2 and magnesium to even absorb it. And if not, if it's not absorbed, it' syou don't want it floating around in your body because it's gonna cause imbalances. So I love that you're saying it. So B12, number one, vitamin D, number two. Is there a third or any others that are issues?
Danielle
Yes, Excess vitamin zinc. And I see this every year during cold and flu season, and it was rampant during COVID So too much zinc can spike testosterone. Testosterone is the key hormone. That and dihydrotestosterone. But testosterone is the key thing that when it spikes, can create hormonal acne. And it spikes throughout the day, and it spikes from various different things. But taking too much zinc, like a standalone zinc supplement, it's usually like 300% RGV. That's where you can start seeing hormonal acne around the mouth. And I see it kind of on the mustache. I don't know why it gets right there. But like on the upper lip, I've seen that from too much zinc and then vitamin B7, which is biotin, that doesn't have so much of a hormonal impact, but it can make you produce excess keratin. That's why it's in all the hair, skin and nails supplements. And excess keratin protein is one of the core genetic factors of acne in the first place. So if you've ever taken a hair, skin and nail supplement, it can have like 10,000 to 80,000% RDV of biotin, and you start getting little bumps everywhere. Yeah. So those are the four main ones.
Kaylee
One other one that I we feel is so important to mention, we've really only seen it become rampant in the last two years because so many more products are being formulated with it. And that's stevia. So there's a lot of research coming out right now that stevia in excess amounts acts as a progesterone blocker. So it's mimicking effects of birth control. By no means is it necessarily acting as a birth control to not get you pregnant, but it is linked to infertility issues through some of these studies and also linked to acne through some of these studies as well. Because of the hormonal impact that it's having by blocking testosterone. Yeah, excess amount.
Dr. Axe
I saw there's one study on that that I'VE seen. And they were doing very large doses. Very, very large doses. But, yeah, that's, that's the interesting thing.
Kaylee
About it, though, is we're. We're now at the day and age where sometimes people are consuming up to 15 different products that have it.
Dr. Axe
Understood.
Kaylee
Yeah. Their energy drink, their protein powder.
Dr. Axe
And so if you're drinking stevias every day.
Kaylee
Exactly. Putting it in your coffee. So the excess doses and buildup, and if people are not detoxing properly. We've been seeing this a lot in blood work lately. People's detox pathways are backed up, and so it's building up in the body over time. It's not saying that if you have stevia every single day for one week, you'll start breaking out. But we're now compounding a year, two years, detox pathways are clogged up. And so again, it's coming back to the very first thing everyone should be doing is making sure those detox pathways are open. We're having bowel movements, we're sweating, we're getting it out. But it's just something to be aware of. We don't like to create fears of everything, and everything is in the dosages. But just being aware of how many products throughout the day you're consuming with stevia, it's not a bad thing. It's just looking at how many things have it and just limiting it. Maybe it's your protein powder, whatever, that is, just limiting the amounts.
Dr. Axe
Yeah. I'm glad you're saying this. One of the things, and this is why I just. This isn't me pushing back. This is me agreeing but also wanting to clarify. But I have people, sometimes they'll hear stuff like this, like, I'm not gonna do any stevia. And the reality is, is that I think generally stevia has been used for thousands of years. It was used in Native American medicine to sweeten teas. It's used in Japan, and they also.
Danielle
Used it as birth control.
Dr. Axe
I mean, it's used everywhere. Again, what you're talking about, though, is incredibly high doses. And it's been used as medicine in Asian medicine for over 4,000.
Kaylee
Yeah. In the buildup, the doses in the buildup for people that aren't exactly.
Dr. Axe
It's the very same thing. You shouldn't eat five cups of blueberries a day. It's just way, way too much for people. And so I think that's. That's where this sort of imbalances. And, you know, I had a patient once. Now, this wasn't Stevie. This was Splenda. This was sucralose.
Danielle
Yeah.
Dr. Axe
And they were doing cups and cups and baking. They had to be admitted to Vanderbilt because they got chlorine poisoning. Because if you. Because if you have too much sucralose, it breaks down into chlorine in your body. And so anyway, to the point, there's always that 1% of people that don't, you know, they're the people drinking, you know, 10 zevias a day on the hour, 20 cups of coffee.
Kaylee
I'm seeing that though, especially like with electrolyte powders. People have four to five electrolyte powders a day, and it's in their greens powder and their protein.
Dr. Axe
Actually, I have another patient I'm working with, and it's a male who has prostate issues and kidney issues. And he started to have a lot of his kidney markers go up because he was doing so much. Some of these electrolyte powders, it's just too much. It is, yeah. And the other thing, just to touch on electrolytes for a minute, some of these, the number one selling brand right now, they're a 5 to 1 ratio of potassium to sodium. Unless you are running a marathon or a triathlon, you don't need that much sodium. It's way, way too much. Most people need more potassium. They're much more potassium deficient. So a lot of these, even products that are formulated today, they're just grossly off. So people are, you know, sodium will cause your body to hold on to water, potassium will release it. It's more detoxifying.
Kaylee
What ratio do you like?
Dr. Axe
It just so much is depending on how much you sweat. If you're a person that's not sweating much, I like actually higher potassium and lower sodium because that's what you're going to get in fruits, it's what you're going to get in vegetables. I don't even really, I mean. So I want to hire, if you're sweating a little bit, a one to one or moderately. A one to one is probably more. More correct. If you're a professional athlete who sweats a lot, you could probably get away from a 1, 2 to 1 or even a 5 to 1 ratio. If you are like sweating buckets and buckets and buckets. But it's, you know, that's so helpful.
Kaylee
For people just to hear and understand.
Dr. Axe
Yeah, I love that you guys pointed out the zinc thing because so many people, the zinc sales of products, I know this because I've owned something because the zinc sales went through the roof during COVID I mean so, so high. And I like zinc. There's some people, actually I've had people who had acne and they started doing zinc and it got better. I mean really, if you're deficient.
Danielle
If you're deficient. All about that, Goldilocks. We don't want to be too low, we don't want to go way too high.
Dr. Axe
And the thing though that people, if they do a zinc supplement that only has zinc, it almost always imbalances copper. And copper is an antiparasitic, it's an antiviral. It's probably, it's so where zinc strengthens the immune system. It actuallyif, you decrease your copper, your body can't fight pathogens as well, like parasites, which can cause acne issues. So I think just when people are buying supplements, buying something that's balanced, more food based, more, you know, in that realm is always better.
Danielle
We're such advocates of getting it through your nutrition. The whole carnivore diet had a moment and everyone's having steak for breakfast, lunch and dinner. Now that's, that's like the diet crazes are just funny to watch. I follow the blue zone principles of some kind. So that is what makes me feel amazing. And I'm the most acne prone individual like on the planet. Even today at 40, I'll still break out if I have like eggs are another secret acne trigger. Egg white protein can be a big trigger for a lot of people. If I have an omelet, I will literally wake up with a cyst like within two days.
Dr. Axe
Yeah, the eggs are very dampening and they're going to create that sort of excess moisture as you're talking about.
Danielle
I love that you know that some people like. No, they're a superfood. How dare you make me think differently about eggs. Like they break people out like crazy.
Dr. Axe
You know, my entire career I've really tried to focus on personalized medicine because to your all's point, everyone is radically different. I mean if I have somebody come in with inflammatory bowel disease, I have them eat almost all soup. If I have somebody with cancer, soup is amazing. Yeah, yeah. In zero raw food, no salads, versus somebody with cancer, I might have them do a good amount of raw food. So just it's very dependent upon the person. And I think this is why the more in tune somebody can become in with their own body, watch what works for them. I think that's incredibly important. But there are so many women struggling with what you guys struggled with, which is acne. Walk me Through. What do both of you eat typically for breakfast, lunch, and dinner to optimize your skin health?
Danielle
I just started recently incorporating more soups like bone broth. I like to make a big vat of it at the week, and then as the week goes on, I'll just change the flavor each day by adding turmeric or ginger. A really good, like, bone broth soup with, like, vegetables, carrots, celery. It's just what I like. Kind of that, like, comforting chicken noodle soup feeling. So I do that. Or I do chia seed pudding with, like, coconut yogurt. I do the cultured one. I'll add cinnamon. I'll add mint. I like to make the colorful thing. Like, everything has, like, five colors. I'm not hungry in the morning, and I do realize it's important to start your day off with protein. So I make a big matcha in like, a big mason jar thing, and it has a ton of water. And I do a scoop or two of the protein powder, getting like 30 grams of protein, if not more right there. And then I go about my day. At 10:30 is when I'm hungry. Then I'll make either like, ground lamb or ground bison. I put something pickled, either pickles or pickled onions or kimchi. And then I'll do like, some sort of herb like dill, cilantro. I don't eat a ton of carbs. I get that through fruit, fruit and vegetables. So I don't, like, do. I don't feel like I need grains. Maybe if I'm working out, I'll add some of that. But it's generally like some really clean ground meat with a bunch of. Of green herbs, arugula, pickled things. And it's very fun.
Dr. Axe
Nice. How about you?
Kaylee
I wake up in the morning, I drink like a big mason jar full of water. First thing in the morning.
Dr. Axe
You guys, your mason jars.
Kaylee
Oh, my. It helps me drink a lot of water because when I. If I. If I'm ever traveling and I don't have my mason jar, maybe a mat, an Airbnb, or a house with just a cup. I really struggle to get enough water. Cups are tiny. And I always, like. I like, use leftover soup, mason jars. But I'll drink a whole thing of water, usually with a little bit of lemon. Lemon. And then I have about 20 to 30 grams of protein through a bone broth protein powder. And I have that just blended with water. I've recently been eating. Before I work out my whole entire life, I always used to work out fasted and I just feel like my hormones really want to eat before now, but not something heavy. So my body's been thriving having protein, bone broth, protein powder right before I work out. And then after I work out I might make another one or I have like my favorite protein bars, rawr bars. They are like homemade out Wisconsin. Like this family. I'm obsessed. Yeah, they're like whole food based so I normally have one of those and then I'll have my coffee after I work out. I love coffee. So I'll have my cup of coffee then lunch is normally just an herby salad, usually arugula. I'll just buy a bunch of random herbs at the market. Whether it's dill, parsley, mint, basil, throw that in with some type of protein. It's usually whatever I made for dinner the night before. So whether it's like salmon or steak or chicken and then dinner is typically a fish or a steak with an arugula salad.
Dr. Axe
And that's a good diet. That's a clean diet right there.
Danielle
Yeah. My family is actually Peruvian and they do their biggest meal like a lot of places in the world, which I think is healthier. They do their biggest meal for lunch so they have time to burn it off, metabolize it off. I don't feel that good when I have a bunch of steak and then go to bed. So I'll try to do my heaviest meal. I do like almost a pound of meat like during the day. That kind of recipe I described, I'll just eat that throughout the afternoon and then at dinner it'll like generally be fish or more soup. I like fermented miso like the Okinawa one.
Dr. Axe
Yeah. You know there's a, the ancient Chinese medicine principle around diet is eat like a king for breakfast, a popper for lunch and a peasant for dinner.
Danielle
I've never heard that. That's so spot on.
Dr. Axe
They're very much like eat a smaller dinner because you want to give your body so much time to digest and sleeping on and also have a three hour block from when you eat at least to when you go to bed and then walking around your meals.
Kaylee
Yes.
Dr. Axe
And so those are, you know, love.
Kaylee
Walking after a meal.
Danielle
Digestion is huge for skin.
Dr. Axe
Yeah.
Danielle
If you increase digestion, you know this right. If you, if you optimize digestion, you have a cascade positive effect on nearly every other system in the body. Would you agree with that?
Dr. Axe
Oh yeah, 100%. Yeah. It's connected to everything.
Danielle
Yes. It's really especially connected to people's Skin. A lot of people aren't digesting their macros and they think digestion, gut health. Okay, Probiotic. Where we see a lot of people have the issue is actually in the stomach. Like not enough enzymes, not properly chewing their food, low stomach acid. That's where you don't break down your food and the chaos starts. So we're big proponents of maximizing digestion. Apple cider vinegar before meals. Hot water with lemon before meals. Sitting and chewing the food thoroughly makes a huge difference in your skin.
Dr. Axe
Yeah, yeah. And part of that too is not rushing. You know, of course cortisol is going to go up. I encourage people to not be on a tablet or a computer or your phone. Just when you eat. Just eat and just either look out the window or have the conversation with the person in front of you and just really take time to relax and not be working while you're in the middle of eating. And that, you know that I've noticed this. If everybody would do this, if they would sit down and notice if they're doing something when they're eating, they will eat so much faster. If they just sit there and just take a few deep breaths, you will eat. It'll take you twice as long to eat, but that's what you. That's what you want.
Danielle
And you end up eating so much less, too. I have that issue all the time where I would just, like, shove a bite in my mouth, be looking at something else. I wouldn't even chew my food and I'd already have another bite loaded.
Dr. Axe
Yeah.
Danielle
And I'm like, why can't I lose weight? Wait, why? Why is this such a thing in my family where like, none of us are thin and I paid attention to just setting the fork down in between bites and thoroughly chewing my food. I eat like a third as much as I used to, but I'm three times more satisfied.
Dr. Axe
That's so good. Hey, Dr. Axe here. I want to let you know about an absolutely incredible and cutting edge line of skincare called Clear Stem. That stands for clear skin and also helping stem cell production. You know, I am a big fan of stem cells because they've helped me heal and regenerate my body. And now I want to do that not via my skin. If you've dealt with breakouts, you know that typical acne products, they dry you out, they damage your skin, while traditional anti aging products tend to be all oily and clog your pores. Well, Clear Stem is really different. It's comprehensive. Also, it's backed with rigorous scientific study studies and evidence. And unlike other skincare brands, Clear Stem is dedicated to both product safety and efficacy. I want to encourage you to discover Clear Stem, what I believe is the most powerful skin care line for helping acne and stem cells, helping you look younger. You can go to clearstem.com d r a x e and use the code Dr. Axe for 15 off. You know, there are a lot of skin care treatments out there. I'd love to hear from you what you like, what you maybe think is overrated. Everything from, you know, laser therapy to again, listen, you guys, you guys are going to tell I'm not that educated in skin care. I know some of the Chinese and ayurvedic metal principles. I know the diet, but in terms of some of the treatments, so. But you know, everything from vampire facials to Botox to the red light therapy, what are two or three you're saying? I really like this. I really think this works. Here's a couple that I just don't think are good in the long term and aren't that healthy for people.
Danielle
Yeah. So I love micro needling. If you have any sort of textural concern, whether it's wrinkles or old scar damage, anything where it's like the texture, microneedling should be your first stop before you go and do a laser. But why? Because it doesn't have heat and because it's the lowest downtime, so you have a shorter window of possibly hurting yourself after the treatment. Everything comes down to post care and the longer the post care window, the more damage you can accidentally do. So microneedling, you can usually go back to your normal routine within five days. Days. And there's no heat. So it's not going to really trigger melasma or trigger pigmentation concerns. Pigmentation concerns come when you add heat to things. So microneedling is great. Microneedling with prp, even better. If you do that once a quarter or if you're, you're like, I really, you know, I turned 40 and I want to really invest in my skin care. Do a series of three of those. You're going to look very different and there's very minimal like risk or downside. So love microneedling. If you can afford the PRP part of it because it is more expensive, it is worth it. Red light at home. Fantastic. We love red light. Gua Sha is fantastic too. But as far as like in office treatments, depends on what you're trying to do. I'm not personally a huge fan of really high heat lasers. I pigment really easily and I actually got hypo pigmentation where my skin turned white. And that's like pretty much irreversible. And that happens a lot. Or if you do a high heat treatment, like a, you know, CO2 laser or something like that, it can be great temporarily, but then you notice four or five months later, you have melasma in places you didn't have before. So there's just a lot of downside that can come with super high heat treatments, especially if that practitioner doesn't know your skin. So the. I, I just, I stay away from those.
Dr. Axe
What's it called where I. One time I went and got my, you know, a skin treatment done. This is a while ago. And it felt like they were taking rubber bands and like flicking me in the face.
Danielle
That's an ipl. Or for you, you have a little more redness. So it could have been like there's IPL's intense pulsed light. That's what you're describing. It feels like the rubber band.
Dr. Axe
Okay.
Kaylee
Okay.
Danielle
Yeah. Was that to get rid of some spots?
Dr. Axe
Yeah, I just had a little bit. A couple little red spots on the side of my face and my cheek. And so it was. Yeah. I mean, it wasn't pleasant, you know, it was not pleasant. I thought I was going to go in and get like, you know, pampered and it was, you know, rubber band.
Danielle
Yeah. No, no pampering with lasers. A lot of crying.
Kaylee
Another reason why we don't like the CO2 and to what Danielle was saying with the high heat is it causes fat ablation.
Danielle
It can cause fat ablation and, and.
Kaylee
People do that and then they may notice a loss of volume over time. So then they're going and getting fillers or injectables to re. Put that volume back in. And so that's why we like the skin treatments without heat, like the microneedling, micro needling with prp, because then you're not having that possible concern of loss of fat in the face.
Dr. Axe
I did that one time with my wife because she, again, she had done this regularly at home. And it felt very cool, you know, very. The opposite of heating. I mean, partly, you know, the PRP we kept in our freezer. So that's probably why it felt so cooling even days after. I mean, it felt very. That was probably my favorite treatment I'd ever, ever done.
Danielle
Even for folks with rosacea or other skin concerns, microneedling can be really, really healing. For ladies that want more of a lifting effect. I really like the ultrasound lifting technologies that are out right now. There's the old one's called Ultherapy. I used to perform that, like 10 years ago. And it worked. Worked amazing. There's a new one called Softwave that I've done, and I love it.
Dr. Axe
Are you using Softwave? Really?
Danielle
Yeah. Ultrasound therapy is really useful and very effective.
Dr. Axe
I recommend that a lot for orthopedic conditions. I've done it for injuries myself, sprained ankles, things like that too.
Danielle
Is it for sprained ankles?
Dr. Axe
Oh, plantar fasciitis is probably the single best thing because what it does is it helps break up fascial tension. And so if it's the same thing, I'm thinking soft wave or shockwave therapy.
Danielle
I think it's the same thing. It just depends on how many. How deep you're going into the skin where you're trying to hit.
Kaylee
But it's pretty much the same to research this later. I've had three leg surgery, so I have a lot of buildup in my ankle and knee, and I'm like, oh, my God, I need this for.
Dr. Axe
Yeah, for connective tissue fascia, low back pain, knee pain, hip pain. I mean, it's. Yeah, soft wave is amazing.
Kaylee
Okay, I'm gonna. I'm gonna ask you where I should go.
Dr. Axe
Yeah, yeah, yeah. I'll let you know for sure. So what do you not, like, what are some of the, you know, big skincare routines and fads out there? You're just not a fan of long term.
Kaylee
We're not the. I think. We think Botox is to each your own. But. But what people need to know about Botox is that it limit. It's. It can inhibit blood flow, and so it can cause inflammation because of that. Like, we want healthy blood flow to our face, we want healthy cell turnover. And when you're limiting blood flow in certain areas, you're not getting the most oxygenated blood to that area. So that can, over time, it can cause more inflammation, more puffiness, more inability for the lymph system to properly flow. And many times people are getting more and more Botox over time, and that's just building up more and more and inhibiting that blood flow in those certain areas. So that's just something for people to know and understand. Some people only get it once a year, and that way they can allow it to detox out, then they can get it again. But some people are getting it every six weeks, and I think that's. And again, we're back to the dosages of things. It's just important to understand that aspect of both.
Dr. Axe
One of the things just from a, A, you know, maybe a male perspective is. I think that a lot of women think that maybe they're doing it because one of the Jenners are or somebody else is doing. And they're doing it very young. I mean, I've seen women in their twenties and I.
Kaylee
Yes.
Dr. Axe
And I'm just, just to be honest, like I thought to myself, I don't think you look prettier with what you've done. I actually think it looks more artificial.
Kaylee
Yeah, it starts to look the same too.
Dr. Axe
Yeah, exactly. Yeah, exactly. Everyone starts to look more the same. Yeah, I think it's, it's. Yeah, I don't, I don't think it's ideal.
Danielle
I've always felt that way. I don't like doing Botox at all. And it's just because I don't like how it makes me look. Because I think you look cuter and younger when you're a little bit more excited and expressive.
Dr. Axe
Yeah.
Danielle
And it can kind of a lot of Botox. If you look at like the eyebrows that kind of aim down, like the Angry Birds, like that's what happens a lot is your eyebrows just start aiming down and it's. If you look at like little kids when they're smiling and like they're youthful, like the inner parts of your eyebrows should actually be a little bit up. So I think that's where people go a little bit wrong. So they just look really stern and they immediately look older.
Dr. Axe
Wow.
Kaylee
I think another really sad thing, I had a 25 year old the other day text me and ask if she should get under eye filler. And it just made me really sad at such a young age. These concerns that people have like under eye filler at 25 years old, one that is a very dangerous area to be poking around. So if someone is going to get anything under the eyes, it has to be an extremely, extremely vetted, trained professional. Because there's a lot of negative things that can happen when you're poking around that area. But it just made me realize like girls are getting Botox at 18, 19 years old, calling it preventative. And we don't have a lot of long standing research of these things compounding at such a young age. Because to your point, before people were getting them in their 40s and now we have women, girls that want to start when they're 18 years old. And that makes me really nervous.
Dr. Axe
Yeah, yeah, it makes me sad. It makes me nervous. The thing that I think when I see people get that done and maybe that's Just with some of my background, but I think, you know, this with, I think the same with plastic surgery and off. In some cases, not all, but in some is, there's, there's a lack of self worth, lack of self value. There's an identity issue there, you know, that's, you know, that people are overlooking that rather than going to the thing that really they need. Need.
Danielle
Yeah. And there's genuine dysmorphia from being on social media taking selfies.
Dr. Axe
Yeah, well, I was, I'm writing a book now. I mentioned this with Dr. Wilco. We're writing a book together and you know, we're one of the chapters we really get into how social media, big tech has really created this sort of esteem issue. And you know, the research on girls, especially in high school. And so it's very, you know, the comparison of, you know, and all the filters and all the things, you know, it's like you combine a filter with, you know, trying to get the perfect shot with Botox and all these things and it's just not, it's not real.
Danielle
Yeah, it's not real. And it does mess with people's heads for sure. I mean, I take a break from social media and I notice my thoughts are very different.
Kaylee
One of the biggest things that we focus on with Clear Stem is just helping to instill confidence and self worth. Because when you're struggling with acne, a lot of times you're at your lowest. A lot of people in our community are on ssri, depression, anxiety medication, and a lot of it is because of how much they're struggling with their skin too. And when we can help people clear their skin, it changes everything for them. The way they show up in the world, the way they feel. And it's, it's also another reason why we love hosting in person events. Because we want people to look at people in the eyes, in the face and meet in real life and really understand that they're not alone in this journey. When everything is done online, it again perpetuates that dysmorphia, that feeling of not enough, but when we can bring our community together. They just feel so much more whole. They feel so much more seen and heard and it really does help them psychologically. And I think that's one of my favorite things we've done as a brand, is bring people off screen to connect, to meet in real life and provide them the root cause education to clear their skin. Because clear skin really changes everything. Not just clearing up your acne, how you feel about yourself and Your whole body?
Dr. Axe
Yeah. It's huge. Yeah. If somebody has acne or severe rosacea or any sort of skin issue, it is. It makes you very self conscious. It can be debilitating mentally, emotionally. There's no doubt about it. There's no doubt. You know, one of the things I've found over the years is that it really depends upon the person on what tends to work. Like I would just give you an example. In taking care of tens of thousands of patients, I've had it to where they've had acne and I started doing just. We changed their diet, generally just got a little bit better and that. And it went away. I've had it where I gave them a zinc supplement. All of a sudden that went away. I remember one girl, I had her just start doing more antioxidants, basically more berries, some super fruit powders, berries. All of a sudden her acne disappeared overnight. It just. It is so dependent upon. And then some. A lot actually. It's. It's a stress thing. We try a lot of diet things and just all of a sudden when they were able to get the stress down. One of the things I love about the focus that you all have had is it's very holistic. It's. We want to focus on stress. We want to focus on the things you're actually putting on your skin. We want to get the toxins out. We want to do the lemon juice and herbal tea in the morning. People see the best results with a protocol, with an overall life transformation of doing the diet, the herbs, the skin care, all of those things together. Is that something that you guys have practiced in your clinic in San Diego?
Danielle
Oh, yes, yes. We're extremely integrative. When I have a new person come to me for the first time, that appointment is 90 minutes.
Dr. Axe
Minutes.
Danielle
And we usually run over. It's quite the opposite experience of going to like a traditional derm with the HMO and your appointments, like 12 minutes.
Dr. Axe
The average visit is seven minutes.
Danielle
Seven to 12. Yeah, I know, right? And that's what we all experienced. So, yeah, 90 minutes. We go through everything you're eating, when you're eating it, what vitamins you're taking, when you're having caffeine. It's like a full traditional Chinese medicine dietary internal breakdown. Yeah. And then we go through what is. I have them dump everything on the bed that's possibly touching their skin. We go through all of them. Ingredient deck by ingredient deck. Pore clogging ingredients are wrecking people's skin. And it's the Most common fillers that every company is using for skin care, hair care and makeup. There's like about 100 really common pore clogging ingredients, but there's a lot more of them out there. But it's the fillers that are in these products and they're breaking people out. So we removed all of those from the clear stem line. We are like no pore clogging ingredients ever. And that's why people get, get such good results because that's, that's why people are breaking out from the topic. It's, it's internal and external, but topically it's from pork clogging ingredients.
Dr. Axe
One of the trends online right now on social media is doing beef tallow.
Danielle
Gross. We do not like this trend.
Dr. Axe
Let me say this. I have a pretty, pretty. Let me give you the, I'll give you the opinion on it from a. Probably a more of a Chinese medicine perspective. And that is it's probably not good for most people skills skin. Unless your skin is very aged. Unless you.
Danielle
It's very dry.
Dr. Axe
Very dry. And then it can be useful and it can be you. You'll do a lot better with it on your body than you ever would. Your face.
Danielle
Yes.
Dr. Axe
So I actually have used towel, for instance. I've had patients with cracked heels and beef tallow was amazing. I mean, really, really good for those very, very serious deep dry stuff beyond your skin. It seems like that would be like, what is that a rating of in terms of that 0 to 5 rating?
Danielle
It's a 2. So beef towel is a comedogenic rating of 2. So for cracked heels. Absolutely. Knees, elbows, go for it. For your face or anywhere you break out, if you're acne prone, it's not going to be the ideal thing for you. Some people are like, this helped my acne. Well, that's. I had people say that one or two and then I asked them just out of curiosity what they were using. And they were using coconut oil. Coconut oil is a hard five. So if something is perceived as helping, it's probably because it's better than what you were using or your dryness was the cause of your breakout. So can it be helpful sometimes? Sure. Is it the ideal thing? Absolutely not. Unless it's for your cracked heels.
Dr. Axe
Yeah. Anytime you're clogging something, an area of your body and again, different areas of skin are different. Right. It's like you're pulling your elbows and knees. Coconut oil, Go for it.
Danielle
Yeah.
Dr. Axe
Your face, you know, not so much. I love the name of your Brand, Okay. Clear stem, clear skin and using stem cells, you know, stem cell based ingredients. I have had stem cells. One of the reasons I believe I'm even sitting doing this interview I'm walking in today is because of stem cells. I had a very, really serious spinal infection, didn't walk for a year a few years ago.
Kaylee
Oh my God.
Dr. Axe
And stem cells, I believe helped save my life, helped me heal completely. And most people that have skin issues have stem cell exhaustion. In fact, it's one of the nine hallmarks of aging. Somebody aging too quickly is their body isn't producing enough stem cells. And so one of the big focuses on, and even when you look at the ingredients used in like the Japanese diet, there's a lot of stem cells. I mean, you know, astragalus is one, Matcha green tea is another. These are really turmeric. These are really stem, stem cell enhancing foods. And what stem cells are just. For anybody who isn't aware of this, stem cells actually become those new healthy tissues. So if you have skin damage, one of the reasons why it doesn't heal, that acne scar doesn't heal, is your skin isn't producing, your body isn't producing via typically your bone marrow marrow, but it's not producing enough stem cells to help create that new healthy young tissue. And so what you guys have done in your products is you have created and put in ingredients that actually help go and create and produce more of those stem cells on the skin. So talk to me about sort of what caused you guys to sort of, you know, realize that stem cells were sort of this key missing ingredient for people healing acne scars and acne and helping heal the skin.
Danielle
I think it's just my earlier training studying cellular biology, immunology and genetics. Like if you have any sort of background in that, you just fully understand, you just reverse engineer everything back to stem cells, just like you said. So preserving them and utilizing them in whatever modality is beneficial for your concern is just really, really important. Like, they've helped me with like chronic pain that I've had, but that was through iv. So it's just different, right? Yeah, yeah, we have to go to Mexico for that. It's funny that in Mexico is where it's legal and regulated.
Dr. Axe
Well, at least we can do it in skin care, but. Yeah, yes.
Danielle
Yeah, definitely. Yeah. We just, we just have a full and a very integrative and whole body approach to understanding skin conditions, especially ones that are as complex and multifaceted as acne. But there are some things that are True for everyone. Taking care of your stem cells is one of them.
Dr. Axe
Yeah.
Kaylee
And we always found it a bit confusing why no acne lines were focused on healing the scar damage.
Danielle
They're all like benzoyl peroxide.
Kaylee
They just wanted to dry you out and then kind of leave you with that. Because the marketing approach is you do acne and then acne care and then you do anti aging. In the beginning of years of Clear Stem, we had so many people try to give us advice and say you have to pick a lane. You have to either do acne or anti aging. You can't do both. You're gonna confuse the customer. Where are they gonna put you on retail shelves? What section? And we were like, no, that's the whole point. The whole point is no one's tackling both at the same time. And you can have have such better results and faster healing when you do both at the same time instead of just focusing on drying out the skin and then trying to use anti aging after. But then, as we've talked about on the show already, that a lot of the anti aging products have the filler ingredients that just break you back out again. So you're in this vicious, vicious cycle of acne. And when you've exhausted that, you go to prescriptions and then you're doing spironolactone and then you're doing accutane, then you're in that vicious cycle. So we can stop it all just by helping the acne and the scar damage at the same time. And stem cells and our epidermal growth factors have been so helpful for people's skin. Doing it both at the same time.
Dr. Axe
Yeah, it's so powerful. You know, I've done a lot of research on stem cells and they're highly anti inflammatory, so that's going to reduce the inflammation that you know is there with the acne. And they're the most regenerative thing you could ever take in terms of if you really want to create new and healthy tissue, look younger, reverse biological age. There's really nothing more powerful. So I was so excited to have you both on because I hadn't seen anybody who was really tackling acne and different skin and anti aging from this sort of stem cell, from using stem cells in this way. Talk to me about just a couple your products in terms of that. You guys recommend that use now. I used one here just recently and was just so impressed. As I mentioned, I love that there's so much aloe. I love that there's the stem cell Ingredients, A lot of these amazing herbals, everything from frankincense to rose to turmeric. I mean, just really amazing. Walk us through maybe three of your products or so that are really, really effective. And maybe what's in there that making them so effective.
Danielle
Top products, if you are clear stem curious. Number one are moisturizer. So most moisturizers out there have pore clogging ingredients. Like everyone's lotion breaks them out. And if you have chronic acne, you're terrified to moisturize. Like, you know that feeling. And they're not wrong. Most moisturizers have pore cloggers. And when I say most in my professional experience, I would say like 97% of them. I'm shocked if I find a random lotion that is randomly acne safe. So ours is completely free of pore cloggers. And that's where most people should start because very likely that their moisturizer, their current one, is causing them problems. So you start there. My other favorite one is our sunscreen. It's called you'd are sunshine. We want people to go get sunshine. It's 21% zinc.
Dr. Axe
Wow.
Danielle
And it has Gotu cola and green tea, some other ayurvedic calming ingredients. And it creates this little blur effect that just kind of instantly boosts your confidence if you're dealing with like redness or anything like that. So those are my two favorites.
Kaylee
I love our serums. Our serums completely changed my skin. I used to deal with really dry, textured skin, just more dull looking. And I didn't realize how many things I was doing that was clogging my pores with skincare, with makeup. So our clarity serum. It's our mandelic acid serum. Mandelic acid is the Goldilocks of serum. So it's not going to dry you out like crazy, like a salicylic. But it's not as harsh as a glycolic that can potentially cause a little more sun damage and just can be a bit harsh for everyday use. For people's skin, mandelic acid is that perfect sweet spot. It also helps to stimulate collagen. It gets in again, gets in your pore and physically dissolves the clog so it gives the appearance of smaller pores. We all know you can't physically shrink and change the size of pores, but you can change the appearance of it by eliminating the clogs that are essentially keeping your pore more open, so dissolves the clog. We also have turmeric in there, vitamin C. So it's very brightening. I love that. And then our Bounce Back serum with all of our peptides in it, it absolutely changed the lines of my skin.
Dr. Axe
That's the one I used.
Danielle
And I really, really love my third favorite.
Kaylee
It's helped, like my crow's feet, because I bl. So I'm so used to squinting all of the time. So I always had really aggressive crow's feet, even from such a young age. My crow's feet are smoother than they were when I was 16, 17, 18 years old. And also the scrunchiness that comes kind of on the in between my eyebrows smoothed out as well. So our Bounce Back serum has been transformative for my wrinkles.
Dr. Axe
That's so great. Yeah, I saw a lot of the stem cell ingredients in that product too. It was really.
Danielle
Yeah, Bounce Back is our. It's nicknamed our no Botox serum because I made it because I don't like doing Botox. So I made it for wrinkles and it really works.
Dr. Axe
That's so good. Well, Danielle, Kaylee, thanks so much for coming on. This was really, really wonderful. And again, I wanted to have a discussion because so many people are struggling with acne and rosacea. And just as many people, their skin is aging prematurely. You know, we want to look younger. And sometimes we look at people and we think, wow, it's amazing. I'm thinking about, well, this is a male Robert F. Kennedy Jr. I'm like, wow, you're in my own dad. My dad's 75, probably looks like he's in his 50s. And so that's, that's what we all want, right? We want to look 20 years younger. We want to feel 20 years younger. And so you guys have really created an amazing product line and educating. And I know your clinic in San Diego as well is doing some amazing things for people. So thanks so much for coming on and sharing your wisdom today.
Kaylee
Really appreciate it.
Danielle
Thank you for having us.
Dr. Axe
And I do want to mention the woman here were so generous in offering 15% off any of their products. If you want to go to clearstem.com again, that's clear stem.com and if you type in Dr. Axe, that's-E. Why don't you go to clear stem.com you can get 15% off their products. Enjoy those and help you look younger, feel younger as well. They're again, so grateful for you. Thank you for subscribing, for sharing. You know, there's a lot of people out there that don't know the truth about Sunscreen the truth about stem cells, the truth about acne. There's so many people suffering and their self image is suffering, their self esteem is suffering. So really wanted to get this episode out because there are millions of people that need to know the truth about how to have beautiful, healthy skin the natural way, based on science, based on ancient medicine. So I've really enjoyed this episode today. I hope you have as well. Thanks for sharing. Thanks for subscribing. I'll see you on the next episode.
Summary of "Skin Care Mistakes That Are Aging Your Skin (and Wrecking Your Hormones)" on The Dr. Josh Axe Show
Release Date: July 24, 2025
Guests: Danielle and Kaylee, founders of Clear Stem
Topic: Exploring common skincare mistakes, their impact on skin aging and hormonal health, and holistic approaches to achieving healthier, younger-looking skin.
Dr. Josh Axe welcomes Danielle and Kaylee, experts in skin health and founders of Clear Stem, a skincare line focused on stem cell technology for acne and anti-aging. He emphasizes that acne isn't confined to adolescence—it affects women up to menopause and men of all ages.
Notable Quote:
Dr. Axe [00:44]: "Pore clogging ingredients are wrecking people's skin. And it's the most common fillers that every company is using for skin care, hair care, and makeup. So most moisturizers out there have pore clogging ingredients. And when I say most, in my professional experience, I would say like 97% of them."
Danielle shares her lifelong battle with severe cystic acne, detailing unsuccessful treatments with antibiotics and Accutane. This personal struggle drove her to study genetics, cellular biology, and eventually establish the San Diego Acne Clinic. Kaylee complements this with her background in holistic nutrition and her experience of severe acne after discontinuing birth control.
Notable Quote:
Danielle [02:31]: "Don't take advice if you're struggling with acne. You should be getting advice from people that have gone through it and are still kind of prone to it."
Dr. Axe delves into how birth control impacts hormonal balance and skin health. He highlights that birth control can cause significant nutritional deficiencies, particularly in B vitamins and magnesium, and alter the gut microbiome by shifting beneficial bacteria.
Notable Quotes:
Dr. Axe [05:53]: "When you look at some of the other things, there's obviously some vitamin, mineral, nutritional deficiencies that you try and address with patients."
Kaylee [07:45]: "We love panithenic acid. We love all the B vitamins..."
Both Danielle and Kaylee emphasize the importance of gut health and proper detoxification in maintaining healthy skin. They recommend practices like consuming warm water with lemon, engaging in physical activities to stimulate the lymphatic system, and ensuring regular bowel movements to prevent toxins from manifesting as skin issues.
Notable Quote:
Kaylee [06:24]: "When you get off birth control, the most important areas to support are your lymphatic system and your ability to detox."
The discussion transitions to dietary habits that support skin health. Both guests advocate for high-quality protein intake, consumption of fermented foods for gut health, and minimizing processed foods. They also caution against over-supplementation, particularly with vitamins like B12 and D, which in excess can exacerbate acne.
Notable Quotes:
Danielle [37:46]: "I make a big matcha in a big mason jar... and have a scoop or two of protein powder..."
Danielle [29:34]: "We don't like to create fears of everything, and everything is in the dosages."
Danielle and Kaylee discuss various herbs and topical ingredients that aid in balancing hormones and soothing the skin. They highlight DIM for estrogen dominance, 5-HTP for stress management, and liver-supporting herbs like dandelion and echinacea. Topically, they recommend non-comedogenic oils such as hemp seed oil and jojoba oil, paired with hyaluronic acid for optimal hydration without clogging pores.
Notable Quote:
Danielle [09:57]: "Some of the vitamins and nutrients that you want to have extremely healthy skin and help your hormones kind of balance themselves. DIM is extremely helpful for most people."
The conversation shifts to sunscreen usage, emphasizing the importance of mineral-based sunscreens (zinc-based) for their anti-inflammatory properties and hormonal balance. They advise protecting the face, neck, and chest while allowing other parts of the body to absorb natural sunlight for vitamin D synthesis.
Notable Quotes:
Danielle [13:34]: "They were out sunning. That was the generation that was out like putting like baby oil on their skin and holding the towel to reflect the sun even more."
Kaylee [13:57]: "We are also big fans of sunscreen, mineral base, face, neck, and chest."
Highlighting Clear Stem's innovative approach, Danielle explains how their products use plant stem cells and peptides to promote skin regeneration and combat scars without drying out the skin. This dual-action approach addresses both acne and anti-aging simultaneously, unlike most products that target one without the other.
Notable Quote:
Danielle [19:11]: "Most acne products dry your skin out and cause accelerated aging... Our line is right in the middle. It's anti-acne via anti-inflammation and then it's also anti-aging with all the growth factors."
Guests advocate for microneedling, especially when combined with PRP (Platelet-Rich Plasma), as an effective treatment for improving skin texture and reducing scars without the harsh side effects of high-heat laser treatments. They caution against aggressive treatments like CO2 lasers, which can cause pigmentation issues and long-term skin damage.
Notable Quote:
Danielle [46:21]: "If you have any sort of textural concern... microneedling should be your first stop before you go and do a laser."
Dr. Axe and the guests discuss the importance of balanced supplementation. While vitamins like B12 and D are essential, excessive intake can lead to hormonal imbalances and skin issues. They stress the need for personalized dosing based on individual deficiencies and the benefits of obtaining nutrients through whole foods rather than high-dose supplements.
Notable Quotes:
Danielle [27:55]: "We love this question. So, so many women are getting high-quality supplements. They're just taking too much of things and it's not really matching what their deficiencies are."
Dr. Axe [35:56]: "If you do a zinc supplement that only has zinc, it almost always imbalances copper."
Emphasizing the uniqueness of each individual's skin, Danielle and Kaylee advocate for personalized skincare routines. They recommend using non-comedogenic, hydrating products like hyaluronic acid and aloe blends, and advise against using hot water which can damage the skin barrier and exacerbate conditions like rosacea.
Notable Quote:
Danielle [25:15]: "If you're using hot water to cleanse your face or standing in a hot shower and letting that hot shower water be on your face, you're destroying your skin."
The discussion touches on the profound emotional and psychological effects of skin conditions like acne. Clear Stem's mission extends beyond skincare to fostering community and self-confidence, aiming to alleviate the mental burdens associated with poor skin health.
Notable Quote:
Kaylee [52:21]: "When we can help people clear their skin, it changes everything for them. The way they show up in the world, the way they feel."
Danielle and Kaylee highlight key products from Clear Stem, such as their moisturizers free from pore-clogging ingredients, zinc-based sunscreens with calming herbs, and serums infused with mandelic acid and peptides. These products are designed to hydrate, reduce inflammation, and stimulate collagen without causing further skin issues.
Notable Quotes:
Danielle [62:44]: "Our moisturizer is completely free of pore cloggers... we removed all of those from the Clear Stem line."
Kaylee [63:38]: "Our clarity serum uses mandelic acid, the Goldilocks of serums."
The guests express skepticism towards certain trendy skincare treatments like Botox, under-eye fillers, and high-heat lasers. They caution against the long-term effects and advocate for more natural, less invasive methods that support the skin's natural regeneration processes.
Notable Quotes:
Kaylee [49:57]: "What people need to know about Botox is that it can inhibit blood flow, and so it can cause inflammation."
Danielle [60:36]: "They are all like benzoyl peroxide. And if you have chronic acne, you're terrified to moisturize."
Dr. Axe concludes by applauding the integrative, science-backed approach of Clear Stem. He emphasizes the importance of understanding individual skin needs, maintaining a balanced diet, supporting hormonal health, and using effective, non-comedogenic skincare products to achieve healthy, youthful skin.
Notable Quote:
Dr. Axe [65:59]: "By focusing on the diet, the herbs, the skincare, all of those things together, is that something that you guys have practiced in your clinic in San Diego?"
This episode offers a comprehensive exploration of the multifaceted nature of skin health, highlighting the interconnectedness of diet, hormonal balance, gut health, and proper skincare. Danielle and Kaylee provide actionable insights and practical advice, empowering listeners to make informed choices for healthier, more resilient skin.
Additional Offer: Dr. Axe mentions a 15% discount on Clear Stem products using the code "DrAxe" at clearstem.com.
End of Summary