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Brendan Schaub, Bryan Callen, and guest Josh Wolf get real about TRT (testosterone replacement therapy), aging, and what actually happens when you start.

They break down the difference between “bro science” and medically supervised TRT, including energy levels, recovery, libido, and overall health. Callen explains why he started TRT despite already being in shape, while Schaub shares mistakes he made early on without proper bloodwork.

The conversation also dives into how hormones affect performance, mental clarity, and daily life—plus whether TRT is becoming more common for men as they age.

On top of that, the guys get into hilarious and wild stories from the road, including chaotic comedy club moments and real-life situations you can’t make up.

If you’re curious about TRT, fitness, aging, or just love unfiltered comedy podcasts, this episode hits everything.

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