
Hosted by Stephanie Gambetta · EN
A podcast exploring peptides, women's health, longevity strategies, and modern wellness—through real conversations and lived experience. Hosted by Stephanie Gambetta, The Loop Podcast breaks down what’s actually working when it comes to feeling better, aging well, and taking ownership of your health.

Peptides, healing, confidence, and nervous system support all come together in this deeply vulnerable episode of Loop Podcast with Alexis Andra.Alexis Andra opens up about surviving a traumatic gas station fire at just 8 years old, enduring more than 20 surgeries, and spending years hiding her scars and pain from the world. What started as trauma and shame eventually became a journey of healing, confidence, faith, and purpose.Stephanie and Alexis dive into the emotional realities of divorce, identity, motherhood, entrepreneurship, and learning how to stop shrinking yourself to make others comfortable. They also discuss peptides, mitochondrial health, GLPs, mindset shifts, confidence, fitness competitions, and the importance of truly listening to your body.This episode is a powerful reminder that healing is not linear, confidence is built, and your story does not disqualify you from becoming who you’re meant to be.Topics discussed include:Surviving severe childhood traumaBurn recovery and body imageDivorce, shame, and rebuilding identityConfidence and personal growthNervous system healingMindset and emotional wellnessPeptides for recovery, inflammation, and optimizationFitness competitions and body transformationEntrepreneurship and burnoutFaith, community, and healingPeptides discussed in this episode:GLP-1s / microdosing GLPs (metabolic + inflammation research)NAD+ (cellular energy + mitochondrial research)CJC-1295 (growth hormone support research)Ipamorelin (recovery + sleep research)MOTS-c (mitochondrial + metabolic research)Retatrutide (metabolic research)GHK-Cu (“Glow” peptide for skin + repair research)

Peptides, nervous system regulation, trauma healing, and GLP-1 support are all explored in this deeply vulnerable episode of the Loop Podcast.Stephanie sits down with longtime friend and fitness instructor Michele Barnowski for one of the most emotional conversations yet. Michele shares her journey after unexpectedly losing her husband at 45, navigating grief while raising two children, and learning how chronic stress impacts the body, brain, hormones, and overall health.Together, they dive into the realities of widowhood, perfectionism in healing, nervous system dysregulation, therapy, somatic healing, and the role peptides played in helping Michele regain her energy, clarity, and resilience. Michele also opens up about the importance of community, why she joined the Loop coaching world, and how she’s now helping others through their own wellness journeys.This episode is raw, inspiring, heartbreaking, hopeful, and ultimately about rebuilding yourself after life completely changes.Topics discussed:Grief and trauma healingNervous system regulationChronic stress and inflammationGLP-1 microdosingBPC-157 and mitochondrial supportWidowhood and identity lossSomatic healing and therapyCommunity and wellnessFitness, hormones, and agingHealing through connectionPeptides discussed in this episode:NAD+ (energy + cognitive support research)GLP-1 / Loop Lean (metabolic health + inflammation support)BPC-157 (recovery + gut health research)SS-31 (mitochondrial support research)••MOTS-c (metabolic + mitochondrial optimization research)

Peptides, burnout, wellness culture, and social media pressure… this episode gets real.In Episode 54 of the Loop Podcast, Steph sits down with returning guest Dr. Sarah Sarkis for an honest conversation about the emotional side of building a wellness brand in public while navigating peptides, business growth, social media scrutiny, leadership, and burnout.Steph opens up about the rapid growth of Loop, the pressure of running a health-focused company, dealing with Instagram bans and shadowbans, and the emotional toll that comes with constantly showing up online. Together, she and Dr. Sarkis unpack the complicated relationship between wellness culture, body image, ambition, perfectionism, and self-worth.They also dive into:The dangers of peptide misuse and misinformationWhy wellness is NOT one-size-fits-allThe pressure women face online around body imageLeadership, boundaries, and protecting your energyBurnout, overcommitment, and founder fatigueWhy community matters more than everThe future of Loop and peptide educationBuilding a business ethically in a crowded industryThis episode is vulnerable, reflective, funny, and deeply human. Whether you’re an entrepreneur, wellness enthusiast, peptide user, or simply someone trying to balance ambition with real life, this conversation will resonate.Peptides & Supplements DiscussedGLP-1 peptides (metabolic health + weight management)Creatine (strength + recovery support)Amino acids (muscle recovery + protein support)Research peptides vs compounded peptidesPeptides for inflammation, recovery, and optimizationHair growth + skin support discussionsSignup for a free 3 month trial of the Loop Health membership here: www.loop.health

Spine surgery is changing fast… and peptides may play a major role in the future of healing and recovery.In Episode 53 of Loop Podcast, Stephanie sits down with Jeffrey Roh, MD, MBA, MSc of Excel Health to talk about minimally invasive spine surgery, AI in medicine, preventative healthcare, peptide therapy, and why the future of surgery may happen “through a needle.”Dr. Roh shares how traditional open spine procedures are evolving into highly advanced endoscopic surgeries with smaller incisions, faster recovery times, and less damage to the body. The conversation also dives into how peptides like BPC-157 and TB-500 could potentially support recovery, reduce inflammation, and transform orthopedics and spine care in the years ahead.They also discuss: • Why medicine is often slow to adopt innovation • AI, robotics, and the future of healthcare • Preventative healing vs reactive medicine • Why peptides are gaining attention in orthopedics • The overlap between regenerative medicine and surgery • Recovering faster after injuries and operations • Stem cells, biologics, and inflammation research • The future of spine surgery technology • Entrepreneurship in medicine • Mountaineering, discipline, and personal growthIf you’ve ever dealt with back pain, wondered about peptides, or wanted a glimpse into where modern medicine is heading, this episode is packed with insight.Peptides discussed in this episode:BPC-157 (recovery + inflammation research)TB-500 (healing + recovery research)GHK-Cu (skin + repair research)SBO1 / Spine BioPharma peptide research

Peptides aren’t one-size-fits-all—and that’s exactly why most people aren’t getting results.In this episode of the Loop Podcast, Steph sits down with returning guest Anthony Castore for Part 2, diving deep into the real strategy behind peptide protocols, telehealth pitfalls, and why personalized coaching matters more than ever.If you’ve ever felt like peptides “aren’t working” or you’ve been handed a generic plan with no real support, this conversation breaks down exactly why.Steph and Anthony unpack:Why cookie-cutter peptide protocols failThe biggest mistakes happening in telehealth right nowHow to actually build a personalized peptide planWhy “less is more” when it comes to training and recoveryThe truth about GLPs—and why they don’t work for everyoneHow mitochondria health impacts everything from energy to fat lossThey also walk through a real case study of a perimenopausal woman struggling with fatigue, hormones, and plateaus—and how dialing in her protocol, lifestyle, and training changed everything.This episode is part education, part reality check, and part roadmap for anyone serious about optimizing their health the right way.Because at the end of the day—it’s not about doing more… it’s about doing what actually works for your body.Peptides discussed in this episode:SS-31 (mitochondrial support research)MOTS-c (metabolic + longevity research)Tesamorelin (fat metabolism + GH signaling research)Ipamorelin (recovery + GH pulse support research)CJC-1295 (growth hormone support research)Thymosin Alpha-1 (immune support research)5-amino-1MQ (metabolic support research)

Peptides, performance, and recovery are at the center of this conversation.In Episode 51 of the Loop Podcast, Stephanie sits down with Anthony Castore, whose journey into health and wellness started with a simple goal: transform his body. What began as a pursuit of fitness evolved into a deep dive into peptides, cellular health, and performance optimization.Anthony shares how he went from being a 117-pound high school graduate to immersing himself in the world of peptide therapy, conferences, and education, eventually connecting with leaders in the field like Dr. Seeds and contributing to the growing peptide conversation.In this episode, we cover:• Anthony’s transformation from bodybuilding to peptide education • What peptides actually do and how they support recovery and performance • The importance of lifestyle, nutrition, and training alongside peptides • Real-world case studies, including athletes and everyday clients • Simple nutrition frameworks like the “hand system” and 5-10-15-20 rule • Why recovery and mitochondrial health matter more than people think • The role of strength training in long-term health • Anthony’s go-to peptides and how he approaches protocolsThis episode is a powerful reminder that peptides aren’t magic — they’re tools, and the foundation will always be built on consistency, education, and understanding your body.As always, remember that everyone’s health journey is different. Consult with a qualified healthcare provider before starting any new treatment or protocol.Peptides discussed in this episode:BPC-157 (recovery + gut research)TB-500 (tissue repair + recovery research)GHK-Cu (skin + repair research)CJC-1295 / Ipamorelin (growth hormone support research)

“I remember thinking… what if no one listens? What if it’s just bad?”Putting yourself out there is uncomfortable. It’s vulnerable. And at the beginning, it can feel like no one’s even paying attention.In this milestone 50th episode of the Loop Podcast, Steph reflects on the journey from self-doubt and hesitation to building a growing brand, community, and platform centered around health, wellness, and peptides.This episode is an honest look at what it really takes to start something from scratch—and stick with it.Steph talks about:The fear and resistance she felt before launchingWhat the early days of Loop actually looked likeThe biggest lessons from building a business in real timeHow her confidence, voice, and purpose have evolvedThe impact of community and helping others transform their healthThis isn’t a highlight reel—it’s the real process behind growth.If you’ve ever thought about starting something, changing your life, or stepping into something new… this is your reminder that it doesn’t have to be perfect to begin.You just have to start.🎧 Subscribe for more conversations on health, wellness, peptides, and personal growth.

What if confidence didn’t come from changing your body… but from finally accepting it?In this episode of The Loop Podcast, Stephanie sits down with LA-based stylist Chellie Carlson, who has spent over 20 years helping women transform not just their wardrobes—but their entire relationship with themselves.From body dysmorphia to breakthrough confidence, Chellie shares how style can become a powerful tool for self-worth, energy, and identity. This conversation goes far beyond clothes—it’s about stepping into the woman you are today and showing up fully.They talk about:Why waiting to “lose 5–10 pounds” is holding you backHow clothing impacts your energy, confidence, and productivityBreaking free from size obsession and outdated beliefsInvesting in yourself and building real confidenceThe power of sisterhood and surrounding yourself with the right peopleIf you’ve ever looked in your closet and felt stuck, insecure, or unsure of your style—this episode will shift your perspective completely.🎧 Full episode available now.

In Episode 48 of The Loop Podcast, returning guest Dr. Jonathan Zelken joins for a candid, no-filter conversation about plastic surgery, confidence, and the reality behind aesthetic trends.From the idea that plastic surgery is ultimately about helping people feel better in their own skin, to the surprising truth that great results don’t always equal happy patients, this episode dives deep into the psychology behind self-image and transformation.Dr. Zelken shares insights from years of experience, breaking down common misconceptions, underrated treatments, and the growing influence of social media and filters on beauty standards. The conversation also explores the rise of rapid weight loss trends like Ozempic, and how they impact both appearance and overall well-being.The episode blends expert knowledge with real-life experiences, including a personal journey through weight loss, body image, and the challenges that come with chasing an “ideal” look.Whether you’re curious about plastic surgery, navigating your own health journey, or just want an honest conversation about confidence and self-perception, this episode delivers real perspective without the fluff.🎧 Listen now and join the conversation.

“She called me this morning and said… I think I’m ready.”That moment captures what this episode is really about — stepping into ownership of your health.In this episode of the Loop Podcast, Steph sits down with Megan Kasel to share a powerful and deeply personal conversation around fertility, frustration, and finally finding answers.After being met with little guidance from traditional fertility care, Megan began exploring a different path. What followed was a complete shift, not just physically, but mentally and emotionally.Together, they dive into:The reality of navigating fertility challenges with limited answersHow peptides like NAD and KPV support overall health and inflammationThe role of hormone balance in fertilityReal, measurable improvements in sperm health and cycle optimizationThe emotional toll of feeling stuck… and the power of taking controlMegan also shares her journey from corporate retail into entrepreneurship, working inside Loop, and being part of a growing movement centered on education, empowerment, and community.If you’ve ever felt dismissed, overwhelmed, or unsure where to start with your health, this episode will open your eyes to what’s possible.Remember: your health journey is your own — but you don’t have to figure it out alone.