What are bullous skin disorders? Bullae are fluid-filled blisters >1 cm in diameter. They can be caused by infection, mechanical stress, or a malfunctioning immune system. In this discussion, we tackle the latter, focusing on the most common autoimmune bullous (blistering) disorders: pemphigus vulgaris, bullous pemphigoid, and dermatitis herpetiformis. Distinctly, the blisters in each of these disorders involve different layers of the skin and autoantibodies against different proteins.

After listening to this AudioBrick, you should be able to:

Describe the typical clinical presentation, risk factors, pathophysiology, diagnostic features, and treatment of pemphigoid vulgaris.
Describe the typical clinical presentation, risk factors, pathophysiology, diagnostic features, and treatment of bullous pemphigoid.
Describe the typical clinical presentation, risk factors, pathophysiology, diagnostic features, and treatment of dermatitis herpetiformis.

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