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Dr. Shawn Baker
We've done 276,000 clinical trials the United States. It's the sickest, fattest, most disease ridden nation in the world.
Dr. Justin Marchegiani
As we age, we are slowly micropoisoning ourselves to death. That's where the miracle of hydrogen gas comes into play. It is the only selective antioxidant on the surface of mother Earth that I have ever found that has profound impact. This is such a phenomenal gas in the human body and perform performance happens when we restore redox homeostasis, not when we just crush inflammation. If we didn't have the inflammatory process, none of us would ever heal from injury. The reason why I start every morning with all nine of the essential amino acids, all 91 essential minerals and hydrogen gas is because the big data tells us that that is the baseline for human optimization.
Dr. Shawn Baker
What is fascinating about my discovery as.
Dr. Justin Marchegiani
I've unlocked the power of hydrogen and hydrogen gas in the human body. Ultimate Human.
Podcast Host
Welcome back to the Ultimate Human Podcast. Today's episode is a special one recorded live from the health experience in London. I took the stage to break down one of the most misunderstood topics in health. Hydrogen water and how hydrogen tablets can improve your energy, inflammation and recovery. I also dove deep into the science of amino acids, what they actually do in your body, and why they're essential for rebuilding every single cell you have. If you've ever been skeptical, confused, or just wanted to understand the data on hydrogen tablets, this episode will give you the full picture. So whether you're new to hydrogen tablets or already using them, this talk will help you connect the dots and take your performance to the next level. Let's get into it.
Dr. Shawn Baker
Hey guys, how we doing, guys? Welcome, London, awesome. Thank you guys for coming into the ultimate human experience. You know, we curated this experience for a reason, you know, because probably the most often asked question that I get is, you know, what is your morning routine? What do you supplement with? And without sounding like I'm trying to sell you a bunch of supplements, you know, I just give you an honest answer. You know, if you look at the data, big data, you know, very often I think in the United States, we get bogged down in the gold standard of science, which is the peer reviewed, published, randomized placebo controlled clinical trial. But the truth is that in the United States, for example, we've done 276,000 peer reviewed, published, randomized, placebo controlled clinical trials. And we've done this in all kinds of areas of science and all kinds of areas of medicine. And if you look at the outcome, outcomes of the vast Majority of those sciences, it's, it's led to the sickest, fattest, most disease ridden nation in the world. You know, the United States leads the world in, in five things. Infant mortality, maternal mortality, type 2 diabetes, multiple chronic disease in a single biome, and morbid obesity. And a lot of times, yes, randomized, peer reviewed, published clinical trials that are placebo controlled are incredible for getting accurate.
Dr. Justin Marchegiani
Answers to certain hypotheses.
Dr. Shawn Baker
But we have at Big data, for example, we've never done a randomized clinical trial on parachutes. Would anybody jump out of an airplane without one? We've never had a placebo group and a control group said, okay, you guys are going to jump out with a hope and a prayer, right? You're very religious and connected to God and you guys are going to have a parachute and we're going to just see what happens, you know, so very often the challenge with this is we, we take the same data and try to apply it to new knowledge and new thinking. Artificial intelligence, in my opinion, is going to revolutionize the world because artificial intelligence can take 700 trillion independent variables and.
Dr. Justin Marchegiani
It can create an actionable result.
Dr. Shawn Baker
And big data is about to circumvent the entire system. It is about to upend modern medicine in a way that's going to be catastrophic.
Dr. Justin Marchegiani
Catastrophic in a great way.
Dr. Shawn Baker
And I noticed this and knew this for years and years and years as I was a mortality expert, because we.
Dr. Justin Marchegiani
Had access to large Data.
Dr. Shawn Baker
There were 371 million lives in the.
Dr. Justin Marchegiani
Database that I had access to.
Dr. Shawn Baker
And you've heard me say this all the time. If that database could ever see the light of day, it would permanently change.
Dr. Justin Marchegiani
The face of humanity.
Dr. Shawn Baker
And the reason why that database would change the face of humanity is because that database had the day, the date, the time, the location, and the cause of death for 371 million lives. It did not care what was in the randomized clinical trial. It did not care what big Pharma said about lowering LDL cholesterol and reducing cardiovascular disease. It actually looked at big Data. And for two decades I was like, this is all wrong. I'm not saying all of those studies are wrong.
Dr. Justin Marchegiani
And I'm not saying that science shouldn't be peer reviewed and published and we.
Dr. Shawn Baker
Shouldn'T do them in controlled trials. But very often we get so myopic in our thinking because the outcome of a certain trial says this. And that now becomes the gold standard. And then years later, we realized we.
Dr. Justin Marchegiani
Made a massive mistake.
Dr. Shawn Baker
And we've done this with everything from.
Dr. Justin Marchegiani
SSRI Selective serotonin reuptake inhibitors, to statins.
Dr. Shawn Baker
To cardiovascular medication, to psychiatric therapy, to all kinds of areas where the data.
Dr. Justin Marchegiani
Flies in the face of what the outcomes truly are.
Dr. Shawn Baker
And sadly, this cycle takes 10 years.
Dr. Justin Marchegiani
Or 20 years and we realize that we made a mistake.
Dr. Shawn Baker
The entire globe was a part of the largest genomic experience that we've ever conducted on humanity. I don't want to divide this audience.
Dr. Justin Marchegiani
In half and start out by attacking vaccines, because I'm not attacking vaccines.
Dr. Shawn Baker
But the peer reviewed, published, randomized clinical data that was placebo controlled said there was no risk outside of this trial, the risk was very marginal. But we actually had never done an experiment where we put messenger ribonucleic acid into the bodies of millions and millions of people. And now we sort of remember the, the acronym FAFO where we're in the.
Dr. Justin Marchegiani
We'Re in the O part right now.
Dr. Shawn Baker
We're in the find out part, right? And so what I want to talk about today is, you know, what is, what is, what is my morning routine and what, what data do I have to support that morning routine? Why am I such a huge fan of all nine of the essential amino acids? Why am I such a fan of mineralizing the body? Why am I such a big fan of hydrogen water? What do those do in the human body? What's the data say? And what does the big, big data.
Dr. Justin Marchegiani
Say about these things?
Dr. Shawn Baker
And, and so if we start with what I think is one of the greatest discoveries of our millennia, it's not just those specific hydrogen tablets.
Dr. Justin Marchegiani
These are the tablets that I take because they create 12 parts per million hydrogen gas.
Dr. Shawn Baker
But what does the data say about.
Dr. Justin Marchegiani
Hydrogen in human beings?
Dr. Shawn Baker
What does the data say about how.
Dr. Justin Marchegiani
Evolutionarily we've gotten further and further and further away from this valuable gas? And when we put this gas back into our bodies, we, what does it do?
Dr. Shawn Baker
Why do we need it? Why were rivers and streams so fraught with hydrogen gas? Why did we used to have so.
Dr. Justin Marchegiani
Much hydrogen gas in our gut that fed hydrophiles and now we have entire classes of bacteria that are gone from our gut because we're missing this valuable.
Dr. Shawn Baker
Nutrient, the lightest, most prevalent element in the entire universe. 10% of the body weight of everybody.
Dr. Justin Marchegiani
In this room is hydrogen.
Dr. Shawn Baker
And something as simple as this valuable.
Dr. Justin Marchegiani
Gas has miraculous impact in the human body.
Dr. Shawn Baker
So let's look at what the randomized.
Dr. Justin Marchegiani
Peer reviewed, published clinical trials say that.
Dr. Shawn Baker
Are done in a placebo controlled environment. So I don't offend the big science nerds. But then we're going to talk about.
Dr. Justin Marchegiani
What the real big data says.
Dr. Shawn Baker
So if you're a fan of the science. Oh, well, you guys don't get to.
Dr. Justin Marchegiani
See that this guy's over here. You just get to look at this massive whiteboard.
Dr. Shawn Baker
But I'll tell you what's on the.
Dr. Justin Marchegiani
Other side of this board.
Dr. Shawn Baker
If you had paid for the VIP ticket, you could actually see, could see my whole presentation. But there are so many impacts that this, this phenomenal, phenomenal gas this molecule.
Dr. Justin Marchegiani
Has in the human body.
Dr. Shawn Baker
Again, the smallest, lightest element in the.
Dr. Justin Marchegiani
Universe, which means it can go anywhere in our body. It can't be toxic to your body because 10% of your body weight is actually made up of this molecule.
Dr. Shawn Baker
And what is fascinating about my discovery.
Dr. Justin Marchegiani
As I've unlocked the power of hydrogen and hydrogen gas in the human body.
Dr. Shawn Baker
Is, you know, when you look at the studies, when they look at its targeted effect on certain outcomes, like a 2001 study found that breathing high pressure.
Dr. Justin Marchegiani
Hydrogen gas could cure parasite induced liver inflammation.
Dr. Shawn Baker
Hydrogen gas administration decreased the expression of different oxidative stress markers. These are markers of oxidation in the human body. And we know that oxidation is what happens in our cellular membranes, when our.
Dr. Justin Marchegiani
Cellular membranes rust, sort of a term for rusting inside the human body.
Dr. Shawn Baker
We also know that aging is a progressive decline in mitochondrial function. You know, yesterday I talked about how one of the most fascinating questions I.
Dr. Justin Marchegiani
Was ever asked was, Gary, if you put all of the top experts in the world, the leading experts on aging.
Dr. Shawn Baker
On, on bio optimization, on longevity, all.
Dr. Justin Marchegiani
The PhDs, the MDs, the researchers, and.
Dr. Shawn Baker
You got them to agree on one.
Dr. Justin Marchegiani
Theory of aging, what would that be? And I said, it's a really hard.
Dr. Shawn Baker
Question, but I think we would all.
Dr. Justin Marchegiani
Agree on the theory of immuno fatigue, a slow, progressive overwhelming of the immune system. As we age, we are slowly micropoisoning ourselves to death. And our immune system has gone from spending the vast majority of its time policing us, not protecting us, policing our.
Dr. Shawn Baker
Own cellular physiology, looking for senescent cells, cells that have hung around too long.
Dr. Justin Marchegiani
In your bloodstream, that can no longer perform their function. Everybody in this room has a certain percentage of senescent cells in your body.
Dr. Shawn Baker
These are red blood cells that are.
Dr. Justin Marchegiani
Alive, but they can no longer carry oxygen.
Dr. Shawn Baker
They are platelets that are living, but.
Dr. Justin Marchegiani
They can no longer carry growth factors.
Dr. Shawn Baker
They're white blood cells that are circulating around in your plasma right now, but.
Dr. Justin Marchegiani
They can no longer amount an immune system defense. So they're useless.
Dr. Shawn Baker
They're lazy employees sitting on the payroll.
Dr. Justin Marchegiani
Of your company not doing their job.
Dr. Shawn Baker
And I'm going to teach you how.
Dr. Justin Marchegiani
We can fire those employees and put people in their seat that can actually.
Dr. Shawn Baker
Perform their function right, the immune system actually eats them. So we don't eat employees that are lazy.
Dr. Justin Marchegiani
And maybe you do that in the.
Dr. Shawn Baker
UK you have this thing called redundancy. You can't even fire anybody, no matter.
Dr. Justin Marchegiani
How little they work.
Dr. Shawn Baker
I mean, you guys got the whole equation, screwed it up. At least we fire you in the US so the immune system wouldn't fire you, we would just eat you. You know, so we're, we're cannibals. So the big data, you know, has more to say than even what the peer reviewed research says. What I find fascinating about hydrogen too is that when you, when you look.
Dr. Justin Marchegiani
At the studies of hydrogen gas in the human body and its implication, and.
Dr. Shawn Baker
This was a really interesting study done.
Dr. Justin Marchegiani
In the Journal of Experimental Gerontology published back In November of 2021, what I.
Dr. Shawn Baker
Found fascinating about this study was that they used a control group for six.
Dr. Justin Marchegiani
Months that drank hydrogen infused water and a control group that drank just regular non hydrogen infused water.
Dr. Shawn Baker
And they measured an entire, one of.
Dr. Justin Marchegiani
The best controlled studies I've ever read.
Dr. Shawn Baker
And they used an entire control group. And what they did was they used.
Dr. Justin Marchegiani
Something called a Tet 2 marker of methylation.
Dr. Shawn Baker
Now you know that I am a.
Dr. Justin Marchegiani
Huge fan of methylation.
Dr. Shawn Baker
You know, I've, I've dedicated the entire.
Dr. Justin Marchegiani
Balance of my adult lifetime to the study of genetic methylation because I believe that the foundation of human function, longevity, wellness, anti aging is that our bodies must have the raw material that they need to do their job.
Dr. Shawn Baker
And I will tell you, the three.
Dr. Justin Marchegiani
Greatest deficiencies in human beings worldwide are vitamin D3 minerals and amino acids.
Dr. Shawn Baker
And when you become deficient in any one of these three things, the consequences.
Dr. Justin Marchegiani
Are severe and they are long lasting and they are impactful.
Dr. Shawn Baker
And we rarely trace disease and pathology.
Dr. Justin Marchegiani
And dysfunction back to the actual missing nutrient.
Dr. Shawn Baker
If we just started with the basics.
Dr. Justin Marchegiani
There are nine essential amino acids. Essential means they are necessary for life.
Dr. Shawn Baker
There are 91 essential minerals, which means.
Dr. Justin Marchegiani
They are necessary for life.
Dr. Shawn Baker
There are two essential fatty acids, which.
Dr. Justin Marchegiani
Means they are necessary for life.
Dr. Shawn Baker
So if you don't get those three.
Dr. Justin Marchegiani
You will eventually die.
Dr. Shawn Baker
There is no such thing as an essential carbohydrate. Can we just marinate on that for a second? She almost threw up. Do you mean my croissant is not necessary for life? No, your chocolate is. Yeah, chocolate's the fourth necessary for life. So we, you Know, I think very often in, in, especially in environments like.
Dr. Justin Marchegiani
This, you know, health conferences like this, we can just get paralysis of analysis.
Dr. Shawn Baker
Walking around and, and we can make an argument for nearly every nutrient or every recovery tool.
Dr. Justin Marchegiani
But the question is, what does our body really need?
Dr. Shawn Baker
So I'm a deep believer that every.
Dr. Justin Marchegiani
Human being at least once in your lifetime needs to do a genetic methylation test. The reason why I believe so deeply in that is that that test will tell your body exactly what you are deficient in.
Dr. Shawn Baker
And that deficiency will never change if you have the MTHFR gene mutation. There will never be a time in your life where you can take folate or methyl folate and make the nutrient.
Dr. Justin Marchegiani
Your body needs called or folate or folic acid and make the nutrient your body needs called methylfolate. So you have to supplement with methylfolate.
Dr. Shawn Baker
If you don't, you will bear the.
Dr. Justin Marchegiani
Consequences of being nutrient deficient in that arena.
Dr. Shawn Baker
Your genetics will tell you what your.
Dr. Justin Marchegiani
Body can convert into the usable form and what it cannot. I think it is the most valuable piece of information. I think it is the foundation of.
Dr. Shawn Baker
Where everyone needs to begin their health journey. And I think for those of you that have children, the earlier you start.
Dr. Justin Marchegiani
Them on this journey and stick that cheek swab in their mouth and find out what their little body is deficient in, the more fruitful their entire life will be.
Dr. Shawn Baker
So if the foundation is genetic methylation, we test ourselves. We find out what our body can convert into the usable form and what it can't. And now we have supplemented with the basics. We have given our body the methylfolate.
Dr. Justin Marchegiani
The academy or the trimethylglycine, what our body needs to perform at its, at its best.
Dr. Shawn Baker
Now we go to what should we be supplementing with and why? And again, we just have to get.
Dr. Justin Marchegiani
Back to the basics.
Dr. Shawn Baker
I am a big believer in all things Resveratrol and CoQ 10 and St.
Dr. Justin Marchegiani
John's Wort and Ashwagandha and NMN and nicotinamide riboside, and on and on and on.
Dr. Shawn Baker
But before we go down that myriad.
Dr. Justin Marchegiani
That, that maze of possibilities, we have to cover the basics. If you don't have the nine essential amino acids, if you don't have 91 essential minerals, if you don't have two essential fatty acids, and if you are not reducing inflammation and improving circulation, you are missing everything. It's like when people tell me, where should I start on my wellness journey? Like, what should I be doing to optimize function? I always talk about sleep, whole food and Movement.
Dr. Shawn Baker
And the big data proves this.
Dr. Justin Marchegiani
The blue zone studies have proved this.
Dr. Shawn Baker
That people that are living beyond age.
Dr. Justin Marchegiani
100 have two things in common. Mobility into later in life, sense of community and purpose, and the absence of processed foods. They eat a whole food diet. They cover the basics I'm going to talk about today. And they, and they move and they have a sense of community and a sense of purpose. So we know that those are irreplaceable. We are not going to find longevity in a stem cell, in an exosome, in a red light therapy bed, in a frequency modality. We are going to find it in the basics.
Dr. Shawn Baker
And so this was a fascinating study.
Dr. Justin Marchegiani
Because it looked at a geriatric population and a lot of randomized clinical trials are done on the healthiest of populations. And then we extrapolate what happens in the healthiest of population to the mass of populations.
Dr. Shawn Baker
What's fascinating about this study is they.
Dr. Justin Marchegiani
Did it in the elderly population, which easily translates to the masses. Ultimate athletes don't very often translate to the masses, but the elderly is a great place for us to start.
Dr. Shawn Baker
They used what was called a tattoo.
Dr. Justin Marchegiani
Marker of methylation to measure their methylation. They measured sit stand ratios, they did measurements of cognitive function, short term recall.
Dr. Shawn Baker
Hand eye coordination, speed, timing, agility, long.
Dr. Justin Marchegiani
Term recall, learned memory, focus, concentration, and across the board, all of those metrics improved simply by adding hydrogen gas to their routine.
Dr. Shawn Baker
And this was something that evolutionarily was.
Dr. Justin Marchegiani
Very, very prevalent in our air, it was prevalent in our streams, it was prevalent in our food and was much more prevalent in our, our diet.
Dr. Shawn Baker
They use this therapeutic molecule to regulate.
Dr. Justin Marchegiani
Oxidative stress and inflammation and apoptosis, cellular death.
Dr. Shawn Baker
But here's, here's where the rubber really meets the road.
Dr. Justin Marchegiani
I'm going to get sciency just for a second.
Dr. Shawn Baker
I talked briefly about this yesterday, but in our body we know that we.
Dr. Justin Marchegiani
Have oxidative stressors, right?
Dr. Shawn Baker
Things that create oxidation. When you say something is an antioxidant.
Dr. Justin Marchegiani
What does that mean? Can anyone define an antioxidant for me?
Dr. Shawn Baker
What is has electrons to give.
Dr. Justin Marchegiani
It has electrons to give. Wow. Have you been following me on Instagram studying biomedicine? Oh, you're studying biomedicine. You're a very smart woman. Yes.
Dr. Shawn Baker
It means that it donates electrons.
Dr. Justin Marchegiani
Right?
Dr. Shawn Baker
So when we say blueberries are antioxidants. Yes, they are. Why are they an antioxidant? Because they donate electrons. When you donate electrons to something that.
Dr. Justin Marchegiani
Is causing oxidative stress, you neutralize that stress.
Dr. Shawn Baker
So 50 years ago, we took this theory too far and we developed the antioxidant theory of aging. We said, oh, we're aging because we have too much oxidation. And so the more antioxidants we put into the body, the less oxidation we'll have and the longer we'll live. And we found that the polar opposite was true. We started massive high dose vitamin C infusions and we started massive doses of antioxidants in the sick and the elderly. And associated especially the one of the largest oncology studies ever performed was studied by reducing the oxidative stress in patients with cancer to try to help their body cope with cancer. And we found that it turned cancer into turbo cancers because we suppressed oxidation too much. So what we want in human beings is not to reduce oxidation too much. What we want is something that is called redox homeostasis. It is a fancy word for a.
Dr. Justin Marchegiani
Perfect balance between oxidation and inflammation.
Dr. Shawn Baker
And actually putting those into balance. The question is, how do you know.
Dr. Justin Marchegiani
When you are taking a supplement or you're laying in a red light bed or you're exercising? How do you know when it's too much and when it's the right amount? That's where the miracle of hydrogen gas comes into play.
Dr. Shawn Baker
It is the only selective antioxidant on.
Dr. Justin Marchegiani
The surface of mother Earth that I have ever found that has the profound impact coming from a single molecule.
Dr. Shawn Baker
And the reason for that is this. We can use the innate intelligence of the human body.
Dr. Justin Marchegiani
If I was to take a cell.
Dr. Shawn Baker
And go inside of a cell and.
Dr. Justin Marchegiani
I was to find the DNA, I.
Dr. Shawn Baker
Mean to find the nucleus, inside of.
Dr. Justin Marchegiani
The nucleus of the cell is the DNA. And if you can't tell, I am not an artist, I'm a scientist.
Dr. Shawn Baker
So please forgive my drawings. So inside the cell is the nucleus with the DNA, the DNA is running the show. You have 110 trillion of these inside of your cells. And the DNA is actually not just.
Dr. Justin Marchegiani
Making a copy of itself called replication. The DNA also is writing instructions into the cell. By the way, this is where we screwed up with the vaccine because we stole the notepad from the DNA, its messages that it writes into the cell called messenger ribonucleic acid mRNA. And we made a synthetic copy of that and we said, great. We were actually able to take a.
Dr. Shawn Baker
Message from the DNA that it's sending into the cell. We are able to capture that message. We were able to copy it synthetically. We were able to put it into a pharmaceutical and inject it into the mass population. Only the thing that we didn't realize was the body's intelligence at writing these.
Dr. Justin Marchegiani
Messages has that message degrade.
Dr. Shawn Baker
So if I was the DNA and.
Dr. Justin Marchegiani
You guys were all cell minions, I would be standing up here writing instructions to you, telling you what to do. You go make this protein, you throw this nutrient out, you bring this nutrient in, you make the spike protein.
Dr. Shawn Baker
And I would continue to write these messages.
Dr. Justin Marchegiani
Messenger RNA into the cell.
Dr. Shawn Baker
And as you conducted that task, when.
Dr. Justin Marchegiani
You came back to your desk, that task would degrade. It would be gone when we synthetically copied that message. The synthetic message never degrades. So we can pick up mRNA, synthetic MRNA in the urine of vaccinated patients. Three years after a vaccination, the signal never turns off with hydrogen. It's very, very different. It controls this signal in a very unique way.
Dr. Shawn Baker
So inside of the DNA we have this messenger. Outside of the cell, we have all of this oxidative stress going on. We have an oxygen molecule, what's called an oxygen singlet.
Dr. Justin Marchegiani
Oxygen.
Dr. Shawn Baker
That's really good for human beings, right?
Dr. Justin Marchegiani
Of course it is.
Dr. Shawn Baker
Until there's too much that creates oxidative stress. If you're getting in a hyperbaric chamber, you have to be taking hydrogen enriched.
Dr. Justin Marchegiani
Water either prior to getting in or, or prior to getting or immediately upon.
Dr. Shawn Baker
Getting out, or you have no idea how much additional oxidative stress you have.
Dr. Justin Marchegiani
Put on your body.
Dr. Shawn Baker
You're flooding the blood with oxygen under pressure, forcing oxygen into the cell membrane.
Dr. Justin Marchegiani
Into an area called the phospholipid bilayer.
Dr. Shawn Baker
And if there's too much, it will rust.
Dr. Justin Marchegiani
The phospholipid bilayer. Yes, you might feel better, but if you don't reduce that oxidation, you could be doing more damage with hyperbarics than you are intentionally doing. If you use hydrogen gas after a hyperbaric session, you get a perfect union of oxidative stress.
Dr. Shawn Baker
So you have oxygen singlets. Great. Until there's too much. You have something called superoxide. Have you guys heard of that? In the human body, superoxide is in. Isn't is excellent for human beings until there's too much. We have hydrogen peroxide.
Dr. Justin Marchegiani
All of us have this in our bloodstream and circulating around our cells.
Dr. Shawn Baker
Very beneficial for human beings. Until there's too much. There is one oxidative free radical that.
Dr. Justin Marchegiani
There is no known benefit for in human beings. And that is called the hydroxyl free radical.
Dr. Shawn Baker
So what if there was a way for us to go into all of these oxidative stressors and not push them down too much, but just to return them to homeostasis and when they got right down to the perfect level, stop lowering them. And if we found a hydroxyl free radical to neutralize it, because there's no known benefit. And so we reduce that stress and restore homeostasis.
Dr. Justin Marchegiani
That is what hydrogen gas does in the human body.
Dr. Shawn Baker
It uses a pathway to the DNA called the NRF2 pathway. And that might not mean anything to anybody in this room, but what this pathway does is when you come in the door to the DNA through the NRF2 pathway, you are telling the DNA I want you to be in control.
Dr. Justin Marchegiani
Of the next sequence of operations.
Dr. Shawn Baker
And so what hydrogen does is it influences this pathway, it enters the cell, it influences the DNA to restore all.
Dr. Justin Marchegiani
Of this oxidative stress back to balance.
Dr. Shawn Baker
It restores perfect redox homeostasis.
Dr. Justin Marchegiani
You can't overdo it with hydrogen gas, you can't underdo it with hydrogen gas.
Dr. Shawn Baker
So simply by taking an elemental magnesium.
Dr. Justin Marchegiani
Tablet, and by the way, you can.
Dr. Shawn Baker
Leave it with it for free today, you can sample it back there and.
Dr. Justin Marchegiani
You can take one of those packages, take it home for yourself.
Dr. Shawn Baker
And instead of doing anything different with your morning routine tomorrow, I want you.
Dr. Justin Marchegiani
To take a glass of water, an eight ounce glass of water.
Dr. Shawn Baker
You can pick up all of these for free.
Dr. Justin Marchegiani
While you're here, I want you to.
Dr. Shawn Baker
Put all nine of the essential amino.
Dr. Justin Marchegiani
Acids into that water.
Dr. Shawn Baker
I want you to add all 91.
Dr. Justin Marchegiani
Trace minerals with a mineral salt that is mined in the Baja peninsula of Mexico.
Dr. Shawn Baker
And I want you to drop a.
Dr. Justin Marchegiani
Hydrogen water tablet in there.
Dr. Shawn Baker
When that hydrogen water tablet dissolves and.
Dr. Justin Marchegiani
You have 12 part per million hydrogen gas, I want you to drink that water back and just see how the lights come on.
Dr. Shawn Baker
That is inflammation and oxidation returning to balance. That jolt of energy you feel is.
Dr. Justin Marchegiani
Not stimulation, it is the lack of inflammation.
Dr. Shawn Baker
And so you go through this pathway and you reduce all of these oxidative.
Dr. Justin Marchegiani
Stressors back to normal.
Dr. Shawn Baker
Hydrogen gas is, is the only selective.
Dr. Justin Marchegiani
Antioxidant that we know of that does exactly that through the NRF2 pathway. This is why you see it improving athletic performance in athletes.
Dr. Shawn Baker
You see it improving cognitive function in the elderly.
Dr. Justin Marchegiani
You see it deepening the waves of sleep, REM and deep sleep in the average population.
Dr. Shawn Baker
This is why you see improved athletic performance, because recovery is enhanced by because.
Dr. Justin Marchegiani
Of the delayed onset muscle soreness is reduced.
Dr. Shawn Baker
This is why you see cognitive function improve hand, eye coordination, speed, timing and agility. You know, I manage six of the.
Dr. Justin Marchegiani
Top 10 UFC fighters in the world. Every single one of them I have taking hydrogen Gas. Every professional athlete that I work with is taking hydrogen gas because this is such a phenomenal gas in the human body. And performance happens when we restore redox homeostasis, not when we just crush inflammation.
Dr. Shawn Baker
If we didn't have the inflammatory process.
Dr. Justin Marchegiani
None of us would ever heal from injury.
Dr. Shawn Baker
Right, so, so I wanted to just give you that little bit of background so you didn't think I was just.
Dr. Justin Marchegiani
Pushing hydrogen water to push hydrogen water.
Dr. Shawn Baker
It is a phenomenal, it's a miracle.
Dr. Justin Marchegiani
Molecule in the human body.
Dr. Shawn Baker
And you're more than welcome to read these studies.
Dr. Justin Marchegiani
I mean the big data is even more in support of what several weeks of hydrogen consumption can do.
Dr. Shawn Baker
By the way, this, this study was actually done comparing the effect of GLP1s. By the way, do you know that most people just heard of GLP1s when Ozempic came out? GLP1 is, is a hormone that's released.
Dr. Justin Marchegiani
In the gut in response to nutrient density.
Dr. Shawn Baker
This is why when we eat whole.
Dr. Justin Marchegiani
Foods, we get full faster.
Dr. Shawn Baker
When we eat nutrient deprived foods like.
Dr. Justin Marchegiani
Highly processed foods, we get hungrier faster.
Dr. Shawn Baker
Because these, these highly processed foods are specifically engineered, by the way. Big Pharma and Big Food have known this for decades. There are entire research labs that are designed to do nothing more than circumvent your response to GLP1 to allow you to take in high amounts of calories and secrete zero GLP1. Because if I can get you to take in a thousand calories and have no GLP one response, I can get.
Dr. Justin Marchegiani
You to take in another thousand calories.
Dr. Shawn Baker
And if you have no GLP response.
Dr. Justin Marchegiani
I can get you to take in another thousand calories.
Dr. Shawn Baker
Their advertising is right.
Dr. Justin Marchegiani
You can't eat just one. Right?
Dr. Shawn Baker
Was. Who is that lays potato chips?
Dr. Justin Marchegiani
Yeah.
Dr. Shawn Baker
At least they came out and admitted it.
Dr. Justin Marchegiani
Right?
Dr. Shawn Baker
They didn't just tell you that we researched this so you'd eat the whole freaking bag. Right. And so processed foods are designed to circumvent human physiology. You know the research on artificial sweeteners, the vast majority on our of, of.
Dr. Justin Marchegiani
The research on artificial sweeteners, in fact about 85 of the chemical composition of an artificial sweetener is actually not designed to taste sweet. You know, it's designed to do ding.
Dr. Shawn Baker
The dopamine receptor, it's called the RF1A2 receptor.
Dr. Justin Marchegiani
It's on the back of the tongue.
Dr. Shawn Baker
And it actually gives you a dopamine.
Dr. Justin Marchegiani
Reward for taking in an artificial sweetener.
Dr. Shawn Baker
You ever known somebody that's been addicted.
Dr. Justin Marchegiani
To diet soda, for example?
Dr. Shawn Baker
Why are they addicted to diet Sodas, not because it tastes amazing. It's because that aspartame was hammering the, the RF1A2 receptor. They were getting a dopamine ding.
Dr. Justin Marchegiani
A dopamine reward every time they drank that. This is why whole foods is the secret to longevity.
Dr. Shawn Baker
This is why all of the blue.
Dr. Justin Marchegiani
Zones had the absence of processed foods, not the presence of a dogmatic diet.
Dr. Shawn Baker
It wasn't a carnivore diet that extended life. It wasn't the Paleo diet, it wasn't raw foods, it wasn't keto, it wasn't paleo, it wasn't pescatarian, wasn't vegan, wasn't.
Dr. Justin Marchegiani
Vegetarian, it was whole foods. Right, because they work with your cellular biology.
Dr. Shawn Baker
When they actually looked at GLP1 studies.
Dr. Justin Marchegiani
The release of GLP1 in the gut.
Dr. Shawn Baker
And all they did was add hydrogen rich water to a meal, you secreted.
Dr. Justin Marchegiani
Significantly more GLP1 and in response to a meal eaten with hydrogen rich water than you would to a meal eaten without it. So it is an actual appetite suppressant, not an appetite suppressant, it's a GLP1 agonist. It helped to release more GLP1 and help you feel satiated early.
Dr. Shawn Baker
So we could go on and on.
Dr. Justin Marchegiani
And on about the studies of that. But the reason why I start every morning with all nine of the essential amino acids, all 91 essential minerals and hydrogen gas is because the big data tells us that that is the baseline for human optimization.
Dr. Shawn Baker
The reason why I am enormous fan.
Dr. Justin Marchegiani
Of perfect aminos is because of this.
Dr. Shawn Baker
You know, the reason why we have protein equivalents, 1 kg of body weight.
Dr. Justin Marchegiani
For every gram of protein, you know, or what do you have to take in? 1 gram of protein for every kilogram of body weight is.
Dr. Shawn Baker
Protein is actually useless in the human body. All protein becomes the same thing.
Dr. Justin Marchegiani
What does all protein break down into amino acids?
Dr. Shawn Baker
Protein does not build muscle, protein doesn't.
Dr. Justin Marchegiani
Build natural killer cells. Protein does not build collagen, elastin and fibrin. Amino acids build those things.
Dr. Shawn Baker
Amino acids are the building blocks of life. The reason why we have protein equivalents.
Dr. Justin Marchegiani
Is to try to get to the amino acid equivalent.
Dr. Shawn Baker
So we're gobbling up a ton of.
Dr. Justin Marchegiani
Protein so that we can actually have the right base of amino acids.
Dr. Shawn Baker
But what happens when you're eating protein, men or women, and you get just, you're missing just one of the nine essential amino acids. What if you only have eight of.
Dr. Justin Marchegiani
The essential amino acids in that protein? What happens to the rest of that protein? It gets converted into fat or into sugar.
Dr. Shawn Baker
So if you want to be efficient about protein, you get efficient about amino acids. You fuel the body with amino acids.
Dr. Justin Marchegiani
Yes.
Dr. Shawn Baker
Protein in your diet is really good.
Dr. Justin Marchegiani
And I think protein equivalents are amazing.
Dr. Shawn Baker
It's very rare that women, for example, can actually meet their daily protein equivalent.
Dr. Justin Marchegiani
Without going way over their macros.
Dr. Shawn Baker
It is really hard for women to.
Dr. Justin Marchegiani
Sit down, eat four chicken breasts, six eggs and a fat rib eye.
Dr. Shawn Baker
Unless you're my wife. She you can eat. No, as lean as she is, that woman can put down a rib eye.
Dr. Justin Marchegiani
I'm not kidding. You like nothing I've ever seen but.
Dr. Shawn Baker
Wife, no, you're beautiful and you're, and you're fit as a fiddle, but you can suck down a ribeye. I mean, let's just call a spade a spade. So it's very rare for women to be able to hit those, those amino.
Dr. Justin Marchegiani
Acid equivalent without going way over their macros. This is why I fell in love with perfect aminos, wasn't to sell a product. I don't put products on my platform just to get an affiliate link and push them out to the audience. They have to have a rationale for me to use them every day in my daily life and for it to be a part of my platform. This company wasn't founded by the folks that are behind the desk right there. It was founded by a doctor named Dr. Minkoff. And Dr. David Minkoff is in his.
Dr. Shawn Baker
How old is Dr. Minkoff now?
Dr. Justin Marchegiani
78.
Dr. Shawn Baker
So he's 78 years old and he.
Dr. Justin Marchegiani
Is still competing in full distance triathlons.
Dr. Shawn Baker
That's someone I'll take advice from. He's also an oncologist and a board.
Dr. Justin Marchegiani
Certified MD I have been a part of the miracle healing that he has done in hundreds of patients. We have actually shared clients and walked people out of some of the darkest moments in their life back into some of the brightest moments in their life. And I became an enormous fan of Dr. Minkoff and when he formulated perfect aminos and took me down the rabbit hole of the science about utilization, if.
Dr. Shawn Baker
You had there are no calories, it does not break a fast. It's the equivalent of 29 grams of whey protein. Most of you to get in 29.
Dr. Justin Marchegiani
Grams of whey protein, that is a thick heavy shake about a quart of.
Dr. Shawn Baker
Fluid and whey protein in the same.
Dr. Justin Marchegiani
Amount of amino acid equivalent you would get from one scoop of perfect amino. So you get all nine of the.
Dr. Shawn Baker
Essential amino acids, 99% of which gets.
Dr. Justin Marchegiani
Utilized by the body and 1% gets converted to fat or to Sugar.
Dr. Shawn Baker
If you look at the comparison between whole eggs, meat, fish, poultry, soy, nuts, or branch chain amino acids, which by.
Dr. Justin Marchegiani
The way is really garbage. I hope you guys know that branched chain amino acids are just sugar water, right?
Dr. Shawn Baker
If you, if you look at all.
Dr. Justin Marchegiani
Of the 22amino acids that we have, nine of them are essential. Three of those essential amino acids are branch chain chain.
Dr. Shawn Baker
And the big theory was because those.
Dr. Justin Marchegiani
Three amino acids are utilized at the muscle level, we should just shovel in a bunch of branch chain amino acids. But the truth is, as you shovel in branch chain amino acids, virtually a hundred percent of the BCAAs are converted to fat or to sugar. Leucine, isolucine and valine on their own will not build muscle. You need all nine of the essential amino acids, leucine, isolucine and valine. Branch chain amino acids will not build collagen or elastin or fibrin. You cannot make a natural killer cell. You cannot enhance your hair, your skin, your nails, or build muscle. So let's just dispel the BCAA theory and get back to all nine of the essential amino acids.
Dr. Shawn Baker
So that's, this is the reason why.
Dr. Justin Marchegiani
They made it into my protocol and the reason why I wanted to talk about each of them specifically.
Dr. Shawn Baker
And also, you know, if you look, I talked yesterday about how scary it.
Dr. Justin Marchegiani
Was be if you looked at the comparison of a 1945 soil lineage study to a 2022, which was the last time we did it. Soil lineage study.
Dr. Shawn Baker
You know, our soil used to be.
Dr. Justin Marchegiani
So fertile, we used to use potash.
Dr. Shawn Baker
Manure and we didn't put glyphosate and.
Dr. Justin Marchegiani
Paraquat and insecticides and pesticides and herbicides.
Dr. Shawn Baker
We didn't glean our fields, we didn't.
Dr. Justin Marchegiani
Overproduce crops from the same soil.
Dr. Shawn Baker
When the soil gets that depleted, the animals that eat that soil are depleted, the plants that grow in that soil are depleted.
Dr. Justin Marchegiani
It would fascinate you how nutrient depleted. The vast majority of our food supply is organic or not. The absence of chemicals, herbicides, pesticides and insecticides is not the presence of nutrition. It's simply the absence of chemicals.
Dr. Shawn Baker
So we need to, in modern society.
Dr. Justin Marchegiani
Get back to replenishing our body with the 91 essential minerals that we need, need the nine essential amino acids that we need. And adding hydrogen gas as a selective antioxidant so we don't have to guess about whether there's too much or too little oxidation in our body. That's why I believe that those three are foundational to every single morning routine it will cost you about $3 a day to add those to your morning routine.
Dr. Shawn Baker
And if you don't want to use these products, use a different product.
Dr. Justin Marchegiani
But make sure that your morning routine includes that. Supplementing for deficiency, not the sake of supplementing and covering the basics with amino acids, minerals and hydrogen gas.
Dr. Shawn Baker
You know what else is fascinating about minerals?
Dr. Justin Marchegiani
I also talked about this yesterday, so sorry if I'm repeating myself for a few of you. You know, I spoke at a conference called an osteostrong conference a few months ago.
Dr. Shawn Baker
And this is a, this is a.
Dr. Justin Marchegiani
Franchise that's just dedicated to bone health and bone density and increasing bone strength.
Dr. Shawn Baker
Because we know that these hormetic stressors.
Dr. Justin Marchegiani
In the body are very good for us. We respond by strengthening. If you don't load a bone, it doesn't strengthen. If you don't tear a muscle, it doesn't grow. If you don't challenge the immune system, it weakens.
Dr. Shawn Baker
Right? I mean, the worst thing to ever happen to humanity during the pandemic, and.
Dr. Justin Marchegiani
I'm sorry for you guys that are on the other side of this fence, was residential quarantining, masking and social distancing.
Dr. Shawn Baker
Those actually crushed the immune profile of the planet. We had a global weakening of the.
Dr. Justin Marchegiani
Immune system because you know what human.
Dr. Shawn Baker
Beings are meant to do. What you're doing right now, sitting three feet away from a stranger, getting inoculated with all kinds of nonsense, probably 1800 pathogens you will pick up today. And guess what? None of you will get sick. Because that is a walk in the.
Dr. Justin Marchegiani
Park for your God given immune system.
Dr. Shawn Baker
But when we took people out of.
Dr. Justin Marchegiani
Contact with other human beings, our immune system retreated.
Dr. Shawn Baker
And then all of a sudden you started hearing about things like monkeypox.
Dr. Justin Marchegiani
I was like, what the hell is monkeypox?
Dr. Shawn Baker
I never heard of that. Well, it's always been there. It's just now started to infect people because our immune system was so weak. We're on our eighth iteration of omicron, the mutated virus from. From SARS CoV2. How many of you gotten your eighth booster? Good. Okay. I actually know people that have gotten eight boosters, double vaxxed, boosted. And now you're on your. So if you're following the vaccine schedule, you should be on number eight. Number nine is coming out in the middle of November, so stay tight, catch up, get the last seven, get the ninth one in November. Why do we need to keep inoculating ourselves if we.
Dr. Justin Marchegiani
If it's an actual vaccine that prevents the infection and prevents the spread So.
Dr. Shawn Baker
I believe so much more in our.
Dr. Justin Marchegiani
God given immune system. If we had taken the masks off, reduced the social distancing, and allowed human beings to be, be in contact with other human beings, we would have ended that pandemic 17 months earlier. That is absolutely my, my, my deep belief.
Dr. Shawn Baker
And so the reason why I believe that we need to empower our human.
Dr. Justin Marchegiani
Physiology and not rely on chemicals and synthetics and pharmaceuticals is the innate intelligence of the body far outweighs the capacity of modern medicine to understand it. When we study things in isolation, we usually find out 10 years later that we made a mistake. When you take a cell out of a human being and you put it in a petri dish in a lab, and you look how it behaves in a lab, and you assume that if you take that cell and put it back in the body, it's going to behave the same way, you're wrong. Cells behave in communities just like human beings behave in communities. And unless we study them in the community that they're in, we get very myopic, misguided research. This is what led to selective serotonin reuptake inhibitors. This is what led to statin medications, beta blockers, calcium channel blockers, ACE inhibits, diuretics, all kinds of consequences from these things because we studied them in isolation, not in human beings.
Dr. Shawn Baker
And so as my morning routine, you're welcome to take a picture of that.
Dr. Justin Marchegiani
That's what I do every morning. Some people ask me, how are you.
Dr. Shawn Baker
In your 14th city in 18 days? That's why. Hydrogen water, amino acids, sea salt. And it's amazing that you can get.
Dr. Justin Marchegiani
All 91 trace minerals from sea salt.
Dr. Shawn Baker
But in any case, I was doing.
Dr. Justin Marchegiani
This talk at this osteostrong lecture.
Dr. Shawn Baker
It was fascinating to me how many.
Dr. Justin Marchegiani
Physicians in that audience still thought that our bones were made of calcium, that.
Dr. Shawn Baker
You needed to supplement with a bunch of calcium and then put the bone.
Dr. Justin Marchegiani
Under a load and the bone would actually strengthen.
Dr. Shawn Baker
That's actually patently false. Our bones are actually not made of calcium.
Dr. Justin Marchegiani
Our bones are made of something called hydroxyapatite, same thing your teeth are made out of.
Dr. Shawn Baker
And hydroxyapatite forms when you take calcium.
Dr. Justin Marchegiani
And phosphorus and you put them together, you form something called hydroxyapatite, which forms strong bones.
Dr. Shawn Baker
But in order for calcium and phosphorus to combine, you need 12 minerals. The vast majority of people with osteopenia and osteoporosis, or weak bones, are mineral deficient. They are not calcium deficient. It is extraordinarily rare in modern society.
Dr. Justin Marchegiani
To have a calcium Deficient patient, a calcium deficient to human beings, it just doesn't happen anymore.
Dr. Shawn Baker
And so the mineral deficiency is what.
Dr. Justin Marchegiani
Is causing the demineralization of bones. It's causing the demineralization of our enamel, the demineralization of our teeth. It makes soft teeth, soft bones, and it makes soft skin.
Dr. Shawn Baker
And so this is why I believe.
Dr. Justin Marchegiani
So much, and this is why we put together the ultimate human experience, so you could experience all three of those things. I wanted to give you the rationale behind those things. Why do we do genetic methylation testing? Because what goes into his body and her body and her body and her body are treated vastly different. Different?
Dr. Shawn Baker
No.
Dr. Justin Marchegiani
No two human beings are exactly the same. The mass adoption of things for a population is another very dangerous thing that we do in medicine. We assume that what goes into everyone's body is treated exactly the same thing.
Dr. Shawn Baker
In fact, when the pandemic first happened.
Dr. Justin Marchegiani
And the vaccines first came out, I knew nothing about them.
Dr. Shawn Baker
My initial hesitation was only by observation.
Dr. Justin Marchegiani
Because I sit on the board of the NFL Alumni Association. I'm their health service director. So we have 22,000 professional athletes in this organization and we care for like the nose tackle at the time for the Green Bay Packers.
Dr. Shawn Baker
This guy is 6ft 6 inches tall.
Dr. Justin Marchegiani
Okay? He's, he's bigger than my big boy Drew here. He's a very big boy. Sorry, Drew. There's bigger guys than you?
Dr. Shawn Baker
No one meaner than you. But there are some, they're bigger. So he's 6ft 6 inches tall and he walks around at 340 pounds. I also have a 5 year old.
Dr. Justin Marchegiani
Niece who's 49 pounds.
Dr. Shawn Baker
You will never convince me that these two human beings get the exact same dose of the exact same thing and.
Dr. Justin Marchegiani
Have the exact same reaction.
Dr. Shawn Baker
That was my initial hesitation.
Dr. Justin Marchegiani
I'm like, that doesn't make any sense.
Dr. Shawn Baker
He looks like he swallowed a water buffalo and she's been playing with Legos all day.
Dr. Justin Marchegiani
They don't get the same thing.
Dr. Shawn Baker
And so by hydrating, mineralizing, putting basic amino acids and all 91 essential minerals.
Dr. Justin Marchegiani
You are starting your day by giving your physiology exactly what it needs to do its job. Why don't we just give the body a chance?
Dr. Shawn Baker
I don't want to belabor you guys.
Dr. Justin Marchegiani
I know it's hot in this room. It's hard to sit here and listen.
Dr. Shawn Baker
To a lecture when you're, when you're sitting in the heat.
Dr. Justin Marchegiani
I'll take three questions from the audience.
Dr. Shawn Baker
Because if there are three questions, probably.
Dr. Justin Marchegiani
Three other people have the question yes, ma'. Am.
Audience Member
My son was going to a surgery for brain tumor. What do you recommend to counteract any. No remnants of the radiation.
Dr. Justin Marchegiani
The remnants of the radiation on the brain. So remnants of radiation anywhere in the body and remnants of radiation on the brain are threefold. How old is your son?
Audience Member
He's nine.
Dr. Justin Marchegiani
Okay, so God bless the fact that he's nine because the neuroplasticity of his brain is not going to finish forming until he's about 24 years old. So any of the symptomology he has right now he can grow out of. It is critical that you do methylation testing. So he's supplemented for deficiency. And I would really recommend transcranial red light therapy. Transcranial red light therapy uses more than just red light. It uses high powered lasers to bathe the brain in red light. One of the issues with, with radiation is it destroys the mitochondrial function not at the site of radiation, but at the pathways through radiation. Right. So when they radiate the brain or any other targeted spot in the body for that matter, it looks like you remember those, those old lamps that used to have. I'm sort of dating myself here back to the 80s, but it had a bubble in the middle of it and.
Dr. Shawn Baker
Had a globe and you could put your hands on it and the little.
Dr. Justin Marchegiani
Electricity would like go out to the, to the sides.
Dr. Shawn Baker
So this is kind of what it.
Dr. Justin Marchegiani
Looks like when they radiate, right? They, they take the sphere of the skull and you see all of these different pathways come in. And where they all cross, that's where the radiation is targeted. But it passes through healthy tissue on the way there.
Dr. Shawn Baker
So, so that radiation beam is damaging.
Dr. Justin Marchegiani
That tissue on the, on the way in.
Dr. Shawn Baker
And so this is, is what we.
Dr. Justin Marchegiani
Call diffuse or global radiation damage. One of the best things to regenerate mitochondrial function at its root is with, with in the brain is with transcranial red light. I would also have him doing methylation pathway testing. Neuronic makes a good helmet. Well, Weber makes a good helmet. These, these are helmets that are actually meant to go transcranial. Much higher power than regular red light, which will not. It will reflect off of the dura, not pass through the dura. So I would be using regular transcranial red light. And it's about a three to six minute session a day. These are as light as a bicycle helmet that the, the science has advanced tremendously. And you don't actually target the site of radiation. You target the diffuse global. Both. Both hemispheres of the brain. Yeah. Okay. One more Question.
Audience Member
Thank you.
Dr. Justin Marchegiani
You're super welcome.
Audience Member
I have an osteOpeny and my GP just decided to start with the HRT immediately. And I'm wondering your opinion about HRT because it started to become very common, especially in the uk and I watched a lot of, you know, podcasts and YouTube videos by the scientists from America. So I'm wondering your opinion about hrt.
Dr. Justin Marchegiani
Yes. So I have a very positive opinion about hormone replacement therapy. Here's, here's the caveat. About 70% of the clients that I see that qualify for hormone replacement therapy do not need hormones. And the reason for that is they are deficient in the raw material that their body needs to make hormones. So if you are deficient in something called dhea, which is a very, very common deficiency in perimenopausal and, and premenopausal females, I'm not making any assumptions about you by the way, but is a very common deficiency. Dhea, dihydrate, epi, androsterone is the precursor to make hormones. If you are clinically deficient in vitamin D3, if your D3 is above below 60 to 80 nanograms per deciliter, you are a candidate for low hormones, not for hormone therapy. That being said, I think that you should do the hallmark gold standard test for hormone replacement therapy, which is called a Dutch test. Please don't have your hormones replaced from a simple blood test. A blood test is a snapshot in time. It will tell you your luteinizing hormone, follicle stimulating hormone, progesterone, pregnenolone, testosterone free testosterone and estrogen. As a snapshot in time, what's the most important thing in all of female hormone therapy, and this is critical, is not to treat the level, it's to treat the ratios. This is true in men and women.
Dr. Shawn Baker
If a man is walking around with.
Dr. Justin Marchegiani
Testosterone at a 900 and estrogen at 70, no problem. If a man is walking around with testosterone at 300 and an estrogen at 70, massive problem. This is a dude that's crying at children's movies, right? And has tender breasts.
Dr. Shawn Baker
So you know, the, the, the issue is the ratio and the Dutch test.
Dr. Justin Marchegiani
Will give you the ratio. The second thing is if you are.
Dr. Shawn Baker
Going to replace hormones, you replace all.
Dr. Justin Marchegiani
Of the hormones in the sequence. Hormone replacement therapy is exactly what its name sound like. It is a replacement therapy. If you. I, I always use this example when I teach HRT supplementation classes. If you have two men, let's say one with a testosterone of 201 with a testosterone of 800. And you're going to put them on hormone injections. Who gets more testosterone, the guy with 200 or the guy with 800?
Dr. Shawn Baker
Who gets more testosterone?
Dr. Justin Marchegiani
They're going to get exactly the same amount. The reason why is both of their production is going to zero. So what happens is we make the mistake of treating the level and we believe that putting a hormone into the body is cumulative. It's not.
Dr. Shawn Baker
With supplementation, if you have a B12.
Dr. Justin Marchegiani
Level of 500 and you take B12, it can go to 1200.
Dr. Shawn Baker
It will stack on top of your level. When you replace a hormone, the hormone.
Dr. Justin Marchegiani
That exists in production, your endogenous production goes to zero.
Dr. Shawn Baker
So it is important to replace the.
Dr. Justin Marchegiani
Entirety of that hormone, not to supplement for the difference between where it is and where your GP wants it to be. It's important to supplement for the entire cycle. The best way to get that dosage is to take a Dutch test. And you will usually end up replacing everything from pregnenolone to estrogen. There's three different forms of estrogen. There's E1, E2 and E3. They're, they're. They have different. They. They play different roles at different time in a woman's cycle, meaning some are higher when women are menstruating, some are. Some are higher postmenopausal, and some are higher during Perry and premenopause. So it's important to know exactly where you are in the cycle and there to replace the entire cascade of hormone. By the way, the very same study that linked estrogen supplementation to breast cancer has demystified, delinked the link between hormone replacement therapy and breast cancer. So if you're still one of those people, women, that is apprehensive about hormone replacement therapy because you're, you're worried about the increased risk of breast cancer, that has been debunked. Okay, my team is telling me that we have to wrap it up.
Dr. Shawn Baker
Guys, please. These are free. While you are in here, please experience the essential amino acids. Take one of those Shakers home with you.
Dr. Justin Marchegiani
They're free.
Dr. Shawn Baker
Grab one and if you haven't done your genetic test, please do. Thank you so much. Thank you.
The Ultimate Human with Gary Brecka
Episode 210: Gary Brecka Live at The Healf Experience 2025 In London – Hydrogen Water and Amino Acids
Date: October 16, 2025
In this special live episode, human biologist and longevity expert Gary Brecka (supported by guests Dr. Shawn Baker and Dr. Justin Marchegiani) takes the stage at The Healf Experience 2025 in London. He delivers a data-driven, down-to-earth breakdown of two often misunderstood health tools: hydrogen water and essential amino acids. Through humor, science, and hard-earned wisdom, Brecka unveils why these seemingly simple concepts have profound impacts on health, longevity, and performance. The episode blends research, big data, and practical advice to empower listeners to “cover the basics” and move beyond health fads.
Gary Brecka’s live session distills decades of scientific research, intuition, and big-data pattern recognition into an accessible playbook for optimizing human health. Skip the distractions and biohacking fads—“cover the basics”: test for your deficiencies, supplement accordingly, and let nature’s wisdom (not pharma’s marketing) guide the path to becoming the ultimate human.
To try for yourself: Go back to the basics—test, supplement for your needs, and make sure every morning starts with hydration, all essential aminos, full trace minerals, and hydrogen. (And maybe enjoy a ribeye, like Mrs. Brecka.)