
Hosted by Rhonda Patrick, Ph.D. · EN

Dr. Peter Diamandis is a serial entrepreneur and founder of XPRIZE, a non-profit organization that designs and conducts global competitions that incentivize the development of technological breakthroughs that propel humanity toward a better future. Tony Robbins is an entrepreneur, bestselling author, philanthropist, and business strategist. He provides business and life coaching to millions of people worldwide through his audio programs, educational videos, and live seminars. Diamandis and Robbins are a dynamic duo, having paired up with co-author Dr. Robert Hariri to write Life Force, a best-selling book that describes breakthroughs in precision medicine and health technologies that can help people live longer, healthier, more fulfilling lives – in the very near future. In this episode, Tony Robbins, Peter Diamandis and I discuss… (00:00) Introduction (07:09) How Tony Robbins and Peter Diamandis met (18:08) Tony and Peter discuss their lifestyle habits (29:32) GRAIL cancer screening blood test (30:16) Cleerly AI-driven coronary CT scan (36:13) The role of DNA damage in aging (37:25) Epigenetics, NAD+, and sirtuins (44:33) Interrupted cellular reprogramming (52:15) Longevity escape velocity (57:50) What do we do after longevity is "solved?" (01:04:19) Space travel, gene therapy, and organogenesis (01:21:48) Promises and challenges of future technologies (01:26:10) How mRNA vaccine technology may impact aging Get the show notes Looking for more? Join over 300,000 people and get the latest distilled information on sleep, depression, and fasting straight to your inbox weekly: https://www.foundmyfitness.com/newsletter Try thirty days of our FoundMyFitness premium member to get access to exclusive episodes, emails, a live Q+A with Rhonda and more: https://www.foundmyfitness.com/trial

Eran Elinav, MD, PhD, is a professor of immunology and principal investigator at the Weizmann Institute of Science in Tel Aviv, Israel, where he co-directs the Personalized Nutrition Project. Dr. Elinav is also a principal investigator at the German Cancer Research Center in Heidelberg, Germany. His research focuses on understanding the complex interactions between humans and the bacteria that reside in their gut and how these interactions shape human health and disease. In this episode, Dr. Elinav and I discuss... (00:00) Introduction to Dr. Eran Elinav (06:38) Circadian rhythm of the microbiome (17:17) Lessons from Hunter-gatherers (24:44) Nurturing the microbiome in children (35:16) Triglycerides and cholesterol (38:58) Saturated fat (40:25) Effect of artificial sweeteners on the microbiome (56:10) What causes recurrent obesity (58:17) Impact of caloric restriction (59:26) Intestinal permeability (gut leakiness) (01:19:54) Bacteriophage therapy and precision probiotics (01:34:44) Bacterial role in TMAO risk (01:40:33) Weight gain from smoking cessation (01:41:53) Tips for diet personalization Get the show notes Looking for more? Join over 300,000 people and get the latest distilled information on sleep, depression, and fasting straight to your inbox weekly: https://www.foundmyfitness.com/newsletter Try thirty days of our FoundMyFitness premium member to get access to exclusive episodes, emails, a live Q+A with Rhonda and more: https://www.foundmyfitness.com/trial

In this nearly 2.5-hour episode, Dr. Rhonda Patrick and Dr. Roger Seheult and Kyle Allred of MedCram make a thoughtful, merit-based, and truly comprehensive discussion of COVID-19 vaccination. In addition to being a co-founder of MedCram Medical Lectures, Dr. Roger Seheult is, as you will find out in the conversation, a boots on the ground, critical care pulmonologist. For Dr. Seheult, COVID-19 is not just theory. He sees real sick people and for that reason brings a very special context to this conversation. Furthermore, Dr. Seheult is also an academic and educator. He is an Associate Clinical Professor at the University of California, Riverside School of Medicine and an Assistant Clinical Professor at the School of Medicine and Allied Health at Loma Linda University. He is quadruple-board certified in Internal Medicine, Pulmonary Diseases, Critical Care Medicine and Sleep Medicine through the American Board of Internal Medicine. In this episode, we discuss: (00:00) Introduction (06:58) Vaccination in the young and healthy (12:25) Risk of myocarditis from COVID-19 is greater than for vaccination (16:18) Long-haul COVID is often preceded by mild infection (25:36) The spike protein generated from vaccination is not the same as the viral one (34:16) Biodistribution of vaccine particles (41:17) COVID-19 Vaccine Adverse Event Reporting System (VAERS) (01:06:55) Antibody-dependent enhancement isn't a concern for the SARS-CoV-2 vaccine (01:14:54) Do the COVID-19 vaccines damage human fertility? (01:19:51) Can mRNA vaccines alter human DNA? (01:28:10) Current ivermectin evidence (01:47:40) Delta-variant and breakthrough infections (02:01:42) Viral evolution (virulence vs. immune escape) (02:10:45) T-cell immunity vs. antibody immunity Watch the annotated video Subscribe to MedCram on Apple Podcasts Subscribe to MedCram on YouTube

Dr. William ("Bill") Harris is one of the world's preeminent experts in the field of omega-3 fatty acid research. His work has focused on the roles that fatty acids in play in cardiovascular and neurocognitive health. The author of more than 300 scientific papers on fatty acids and health, Dr. Harris is a professor in the Department of Medicine in the Sanford School of Medicine at the University of South Dakota, the co-inventor of the Omega-3 Index, founder of OmegaQuant Analytics, and president and founder of the Fatty Acid Research Institute. In this episode, Dr. Harris and I discuss… (00:00) Introduction (06:36) Early studies on omega-3s, dietary fats, and cholesterol (14:44) Omega-3s may normalize bleeding times (20:33) Plant-based omega-3s are not equivalent in power to marine omega-3s (25:23) Genetic engineering of plants is needed for sustainable omega-3s in the future (27:18) The omega-3 index reveals individual variations in omega-3 needs (32:13) Red blood cell concentration of omega-3s better reflect long-term omega-3 status (36:41) Genetic variants influence omega-3 dietary needs (54:20) The omega-3 index may predict life expectancy (01:05:03) How metabolites of omega-3 reduce and resolve inflammation (01:17:11) High omega-3 concentrations halve the risk of COVID-19 death (01:20:10) DHA may help keep the SARS-CoV-2 spike protein from entering cells (01:22:50) Concerns over the omega-6/omega-3 ratio may be unfounded Looking for more? Join over 300,000 people and get the latest distilled information on sleep, depression, and fasting straight to your inbox weekly: https://www.foundmyfitness.com/newsletter Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A's with Rhonda and more: https://www.foundmyfitness.com/crowdsponsor

Dr. Roger Seheult Dr. Roger Seheult is the co-creator of MedCram Videos. In the early days of the COVID-19 pandemic, MedCram emerged as a beacon of insight, providing continuing coverage and perspectives in an environment almost defined by information scarcity. What particularly excited me about the unique opportunity of this interview is that apart from Dr. Seheult being a unique voice of public scholarship during the early days of the pandemic, he's also a quadruple board-certified pulmonologist with deep experience working on the frontline of the COVID-19 pandemic. In this episode, we discuss: (00:00) Introduction (06:20) How MedCram Videos got started (09:37) Using evidence to make COVID-19 treatment decisions (12:46) The differences in treating early vs late-stage COVID-19 (14:40) How doctors would've treated COVID-19 one-hundred years ago (18:13) Increasing ventilation reduces SARS-CoV-2 transmission (20:28) Masks are virtually universally beneficial regardless of type (21:32) Vitamin D and COVID-19 (22:22) Steroid chemical structure of vitamin D (23:24) The vitamin D RDA is likely too low (24:23) Vitamin D is more like a hormone than vitamin (26:21) The overlap between COVID-19 and vitamin D deficiency (30:27) How Mendelian randomization studies helped solve the vitamin D puzzle (34:20) The gene regulatory effects of vitamin D (35:49) Vitamin D and the ACE2/renin-angiontensin system (42:00) Daily doses of vitamin D are more effective (43:23) A prescription-only form of vitamin D (calcifediol) may be best for COVID-19 (47:06) Skin synthesis of vitamin D from sunlight can be unreliable (53:43) The safest dose range for vitamin D (01:06:15) The beneficial circadian effect of early morning sunlight (01:07:38) Sleep deprivation impairs vital immunity (01:12:08) Dr. Seheult's suggestions for the best sleep (01:19:18) A Spanish flu era treatment boosts interferon by ten times (01:22:38) Why interferon is so important for the viral response (01:26:43) Treating the symptoms of fever during the Spanish flu harmed patients (01:31:58) Dr. Seheult's ongoing research of hot hydrotherapy (01:47:00) COVID-19 Vaccines If you're interested in learning more, you can read the full show notes. Join over 300,000 people and get the latest distilled information straight to your inbox weekly: https://www.foundmyfitness.com/newsletter Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A's with Rhonda and more: https://www.foundmyfitness.com/crowdsponsor

Giselle Petzinger Giselle Petzinger, MD, an associate professor of Neurology at the University of Southern California, studies the extensive effects of how different types of exercise, in particular skill-based exercise, can affect the clinical outcome for people with Parkinson’s disease. Dr. Petzinger's work focuses on understanding how to promote brain repair after injury, particularly in the context of Parkinson's disease. She is currently investigating ways to enhance neuroplasticity in a preclinical model of the disease. She has examined the role of exercise in Parkinson's disease, with emphasis on how different types of exercise affect distinct regions of the brain. Her work has implications for improving the quality of life of patients diagnosed with the neurological disorder — a condition for which there is no cure. In this episode, we discuss: (00:00) Introduction (06:57) What is Parkinson’s disease? (11:57) When symptoms of Parkinson’s disease appear (14:57) Circuits in the brain can compensate for substantia nigra dysfunction (18:37) Hereditary risk factors of Parkinson’s disease (21:25) Parkinson’s disease is associated with pesticide and pollutant exposure (26:57) Exercise can lower the risk of developing Parkinson’s disease (35:38) How skill-based exercise such as boxing reduces disease symptoms (47:49) Treadmill exercise increased BDNF and brain health (58:33) Exercise at 80 percent of maximum heart rate slowed Parkinson’s disease progression (01:01:31) Why exercise may not fully replace medications (01:09:58) DHA reduces motor symptoms and dyskinesia (01:12:12) Patients with Parkinson’s disease have higher levels of inflammatory biomarkers If you’re interested in learning more, you can read the full show notes here. Join over 300,000 people and get the latest distilled information on Parkinson's disease straight to your inbox weekly: https://www.foundmyfitness.com/newsletter Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A’s with Rhonda and more: https://www.foundmyfitness.com/crowdsponsor

Get a sample of our new premium member's content, known as Aliquots, by listening to this in-depth Q&A mashup on Fasting. What's an aliquot, you may ask? Aliquots are special, curated segments prepared and distributed to premium members via the premium members' podcast feed. In this previous, you'll learn: (00:00) Introduction (01:48) Fasting supports a healthy gut microbiome and reduces autoimmunity (08:28) Increasing autophagy with fasting (13:26) Reducing protein acetylation with fasting mimetics (18:17) Fasted exercise, water fasting, and a fasting-mimicking diet Learn more about our premium podcast feed The Aliquot by clicking here. Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A's with Rhonda and more: https://www.foundmyfitness.com/crowdsponsor

Get a sample of our new premium member's content, known as Aliquots, by listening to this in-depth Q&A mashup on Sauna use. What's an aliquot, you may ask? Aliquots are special, curated segments prepared and distributed to premium members via the premium members podcast feed. In this episode, you'll learn: (00:00) Introduction (01:41) Evidence supporting sauna use for health (04:09) How Finnish humid saunas can reduce viral illness (08:40) Sauna and hot bath use during the COVID-19 pandemic (15:07) Rhonda's sauna routine Learn more about our premium podcast feed The Aliquot by clicking here. Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A's with Rhonda and more: https://www.foundmyfitness.com/crowdsponsor

Get a sample of our new premium member's content, known as Aliquots, by listening to this in-depth Q&A mashup on pregnancy and child development. What's an aliquot, you may ask? Aliquots are special, curated segments prepared and distributed to premium members via the premium members podcast feed. This particular collection of segments covers every single major discussion of pregnancy and child development spanning years of members-only Q&As. In this episode, you'll hear: (00:00) Introducing "The Aliquot" (02:43) Omega-3s for babies and toddlers to maximize brain development (07:02) Common nutrient deficiencies in children and how to prevent them (11:42) Evidence to support omega-3 supplementation in children (20:58) Fasting considerations and restrictions for women Learn more about our premium podcast feed The Aliquot by clicking here. Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A's with Rhonda and more: https://www.foundmyfitness.com/crowdsponsor

This episode aims to be the most comprehensive video compendium on the biology of breast milk ever recorded. In this episode, you'll discover: (00:00) Introduction (07:11) Breast milk production and composition (09:59) Human milk oligosaccharides help establish the infant gut microbiome (16:32) Omega-3s in breast milk boost brain development (18:15) Vitamins and minerals in breast milk (22:05) Breast milk stem cells and multi-organ microchimerism (22:54) Harmful substances transferred to infants via breast milk (28:05) Breastfeeding boosts the infant's immune system (31:17) Effects on intelligence (34:36) Breastfeeding as a benefit to maternal health If you're interested in learning more, you can read the full show notes here. Join over 300,000 people and get the latest distilled information on the biology of breast milk straight to your inbox weekly: https://www.foundmyfitness.com/newsletter Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A's with Rhonda and more: https://www.foundmyfitness.com/crowdsponsor