
Hosted by Rhonda Patrick, Ph.D. · EN

This episode was originally recorded for The Kevin Rose Show. Given some of the unique discussions we had, I had no choice but to ask the great Kevin Rose if he would let me re-post it over here on the FoundMyFitness podcast feed. A request which he graciously obliged. In this episode, you'll discover: 00:00:00 - Introduction 00:08:00 - Increasing omega-3 levels in the brain with phospholipid DHA 00:27:23 - Metformin's effects on longevity and possible harms 00:48:23 - Fasting and NAD+ supplementation 00:50:05 - Getting sulforaphane from food and supplements 01:06:57 - Magnesium L-threonate efficacy for brain health 01:13:44 - Sauna use mimics exercise, improving heart and brain health 01:23:48 - New FMF Membership If you're interested in learning more, you can read the full show notes here: https://www.foundmyfitness.com/episodes/rhonda-krs-2 Join over 300,000 people and get the latest distilled information on sulforaphane research straight to your inbox weekly: https://www.foundmyfitness.com/newsletter Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A's with Rhonda and more: https://www.foundmyfitness.com/crowdsponsor

Rhonda gives a summary of the science of resveratrol including its effects in animals and humans, mechanisms, and the bottom line on resveratrol supplementation and safety. In this episode, you'll discover: (00:00) Introduction (03:39) Resveratrol improves cardiovascular biomarkers in clinical trials (06:49) Anti-inflammatory effects of resveratrol (08:11) Improved cognition and memory in clinical studies (11:23) Resveratrol improved healthspan, but not lifespan, in animals (12:28) Induction of longevity genes via xenohormesis (16:19) Contradictory effects on exercise-associated benefits (20:34) Various factors that affect resveratrol bioavailability (23:09) Unintentional effects on drug metabolism If you're interested in learning more, you can read the full show notes here. Join over 300,000 people and get the latest distilled information on resveratrol straight to your inbox weekly: https://www.foundmyfitness.com/newsletter Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A's with Rhonda and more: https://www.foundmyfitness.com/crowdsponsor

In this episode, Rhonda describes NAD+ (perhaps one of the most important molecules in the human body), why it is so important for aging, and why it declines with age. In this episode, you'll discover: (00:00) Introduction (03:07) Overview of NAD+, a source of cellular energy (09:18) NAD+ fuels PARP and sirtuin enzymes, promoting longevity (12:37) How can I raise NAD+ levels? (17:03) Can NAD+ boosters (NMN & NR) promote cancer growth? (19:15) Making sense of the research so far (27:03) Why not supplement with NAD+ directly? (29:23) Clinical trials investigating nicotinamide riboside are promising (32:42) Recap and concluding thoughts If you're interested in learning more, you can read the full show notes here. Join over 300,000 people and get the latest distilled information straight to your inbox weekly: https://www.foundmyfitness.com/newsletter Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A's with Rhonda and more: https://www.foundmyfitness.com/crowdsponsor

This episode features a Q&A session with Dr. Rhonda Patrick. The questions were sourced from social media followers of both FoundMyFitness and also Zero Fasting Tracker, a convenient mobile app used widely in the fasting community for logging. In this 45-minute podcast, Dr. Patrick answers some of the most popular questions related to fasting, including: (00:00) Introduction (03:46) What effects do coffee, supplements, and amino acids have on fasting? (12:29) Should you consume electrolytes on a fast? (14:50) What evidence is there that one method of fasting is more beneficial than others? (24:01) What effect does the consumption of exogenous ketones have on fasting? (29:30) Are there downsides to exercise during fasting? (34:31) What role does fasting play in the growth-longevity tradeoff? (49:48) What's the ideal way to break a fast? If you're interested in learning more, you can read the full show notes here. Join over 300,000 people and get the latest distilled information straight to your inbox weekly: https://www.foundmyfitness.com/newsletter Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A's with Rhonda and more: https://www.foundmyfitness.com/crowdsponsor

If you're anything like me, having the facts straight can sometimes help you to push through the tough part of building new habits or breaking old bad ones. This podcast talks about the realities of what the science says surrounding the consumption of refined sugar. Some of the facts may surprise you! In this episode, you'll discover: (00:00) Introduction (01:16) Excess sugar consumption is common and dangerous (05:16) Sugar accelerates the aging process itself (09:14) Refined sugar harms the brain (11:22) High fructose corn syrup is uniquely dangerous (14:04) How to quit sugar If you're interested in learning more, you can read the full show notes here. Join over 300,000 people and get the latest distilled information straight to your inbox weekly: https://www.foundmyfitness.com/newsletter Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A's with Rhonda and more: https://www.foundmyfitness.com/crowdsponsor

Does meat consumption cause cancer? Or, put another way… does avoiding meat help prevent cancer? If you aren't already savvy to the topic, this may sound more absurd than it should. Here's why: there have been many, many, many correlative studies that have found that higher meat consumption is associated with a significantly higher risk of cancer and cancer mortality. In this episode, you'll discover: (00:00) Introduction (01:18) How cancer starts (04:49) Growth factors make cancer thrive (08:54) Applying the science to your needs (11:33) Cycle prolonged fasting with recovery and protein Join over 300,000 people and get the latest distilled information on meat consumption causing cancer straight to your inbox weekly: https://www.foundmyfitness.com/newsletter Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A's with Rhonda and more: https://www.foundmyfitness.com/crowdsponsor

The World Health Organization estimates that more than 350 million individuals of all ages have depression and approximately one-third of all patients with depression fail to respond to conventional antidepressant therapies like SSRI's. The good news is that today, good science is starting to illuminate the underlying biological mechanisms of depression. This new understanding may soon help the clinical world develop new and more effective treatments. In this episode, you'll discover: (00:00) The scope of depression and SSRI use (03:37) How inflammation can cause depression (09:26) But what causes inflammation? (12:03) Treating depression with diet Join over 300,000 people and get the latest distilled information on depression and it's underlying causes straight to your inbox weekly: https://www.foundmyfitness.com/newsletter Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A's with Rhonda and more: https://www.foundmyfitness.com/crowdsponsor

Dr. Rhonda Patrick delivers the keynote lecture at the Orthomolecular Medicine Congress in Bussum, Netherlands (MBOG Congres 2015). In this talk, you'll learn about: (00:00) Introduction (04:52) Micronutrient inadequacies and triage theory (10:42) Role of DNA damage in cancer and aging (21:10) Vitamin D, serotonin, and the development of autism (41:39) Omega-3s also regulate serotonin If you're interested in learning more, you can read the full show notes here. Join over 300,000 people and get the latest distilled information straight to your inbox weekly: https://www.foundmyfitness.com/newsletter Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A's with Rhonda and more: https://www.foundmyfitness.com/crowdsponsor

In this podcast, I discuss some of the mechanisms by which chronic stress (and rumination) affect health and aging and how meditation can reduce rumination and buffer stress. In this episode, you'll discover: (00:00) Introduction (02:41) Eustress such as exercise vs distress such as fear (06:15) Effects of stress on the brain (07:30) Effects of stress on the gut and microbiome (10:21) Stress accelerates biological aging (15:04) Meditation reduces rumination and promotes empathy (19:53) Effects of meditation in the brain (24:28) Meditation slows biological aging and lengthens telomeres If you're interested in learning more, you can read the full show notes here. Join over 300,000 people and get the latest distilled information straight to your inbox weekly: https://www.foundmyfitness.com/newsletter Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A's with Rhonda and more: https://www.foundmyfitness.com/crowdsponsor

In this episode Rhonda talks about: (00:00) Introduction (03:00) Heat stress makes the body more resilient to the stresses of aging (14:45) Possible mechanisms why sauna use reduces heart disease risk (16:45) Sauna enhances athletic endurance and muscle growth (28:16) Sauna use stimulates neurogenesis and improves cognitive function and mood (37:34) Sauna use detoxifies BPA, PCBs, phthalates, and other metals (51:10) Practical applications sauna use and other heat stressors like hot yoga If you're interested in learning more, you can read the full show notes here. Join over 300,000 people and get the latest distilled information straight to your inbox weekly: https://www.foundmyfitness.com/newsletter Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A's with Rhonda and more: https://www.foundmyfitness.com/crowdsponsor