Podcast
The Hunter Williams Podcast
Hosted by Hunter Williams · EN
Average health is a choice. And it's the wrong one.
The Hunter Williams Podcast goes where mainstream medicine won't — deep into the science of peptides, hormone optimization, metabolic health, and biohacking protocols that actually move the needle.
Every week, I sit down with elite researchers, doctors, and high-performers to cut through the noise and hand you biological leverage most people will never have access to.
This isn't wellness. This is optimization.
Subscribe. Take control of your biology.
37episodes
Episodes
Newest firstAll episodes
The BPC-157 Masterclass | Complete Users Guide (2026)
4d ago00:47:17Summary readyLinks, cheatsheet, private group and more: https://hunterwilliamshealth.com/linksBPC-157 is the peptide almost everyone starts with. In this masterclass I walk through why, and where the hype gets ahead of the evidence.We have about 30 years of animal studies on this one. We have fewer than 30 human subjects in published research. I keep that line clear the whole way through.I cover what BPC actually does. It helps the body repair tissue. It works on the gut, tendons, ligaments, and even the brain in animal models. It is not a steroid and it does not build muscle on its own. I explain how it works, who it helps, and who should skip it.Then we get practical. Dosing tiers, how to reconstitute the vial, how to inject near an injury, and how long before you feel anything.I tackle the cancer question head on. The fear is plausible on paper. The data does not really back it up. I tell you exactly where I land.We also cover cycling, the Wolverine stack with TB-500, oral versus injectable, and the FDA shift happening right now.Even if you already know this one, you will probably pick up something. If you are new to peptides, start here.
SummarySaturday Morning Coffee Talk 6/20/26
6d ago02:15:57Summary readyLinks, cheatsheet, private group and more: https://hunterwilliamshealth.com/links
SummaryThe KPV Masterclass | The Complete User's Guide
1w ago00:46:46Summary readyLinks, cheatsheet, private group and more: https://hunterwilliamshealth.com/linksKPV is the most underrated peptide out there. Almost nobody talks about it. In my opinion it should be one of the most demanded peptides we have. If I had to choose, I'd take it over BPC and TB-500 every single time.Here's why. KPV is a tiny three amino acid fragment of alpha-MSH. It directly blocks NF-kappa B, the master switch your body uses to turn inflammation on. Most peptides work around the edges. KPV shuts the alarm off at the door.In this one I cover all of it. What KPV is and how it works. Who actually benefits. Dosing by tier and by purpose. How to stack it with BPC, TB-500, LL-37, and your GLP-1. What to track on bloodwork. Cycling, sequencing, troubleshooting, and a full FAQ.If you've ever run a protocol that worked and then stalled out, this one is for you. Inflammation is almost always the rate-limiting step in healing.Make sure you're on the email list. And come join us in the Axion Collective for live coaching every Thursday.⚠️ For research and entertainment purposes only. ⚠️
SummaryThe Tesamorelin Masterclass | The Complete User's Guide (2026)
2w ago00:47:58Summary readyLinks, cheatsheet, private group and more: https://hunterwilliamshealth.com/linksTesamorelin is one of the few peptides I've seen actually move the needle on body composition. So I made a full masterclass on it.This is the user's guide as it stands in 2026. I cover what tesamorelin is, how it works, and the best practices I'd recommend for using it.We get into the growth hormone axis and why a GHRH is different from a GHRP. I break down the clinical data, the 15% visceral fat reduction, the liver fat numbers, and the cognition research almost nobody talks about.Then we get practical. Dosing, timing, fasted injections, and the cycling patterns I actually use. I share why I stay at one milligram instead of two and what the water retention tradeoff looks like at higher doses.I also cover stacking with testosterone and GLP-1s, reconstitution, injection technique, side effects, and the people who should skip this one entirely.I'm honest about the limits too. Some of this evidence is strong and some of it isn't. I tell you which is which.If you're thinking about tesamorelin or already using it, this is everything I'd want you to know.
SummarySaturday Morning Coffee Talk 6/6/26
3w ago02:15:18Tap to summarizeLinks, cheatsheet, private group and more: https://hunterwilliamshealth.com/links
Transcribe →The Complete TB-500 Masterclass: Dosing, Stacking, and More
3w ago00:30:03Tap to summarizeLinks, cheatsheet, private group and more: https://hunterwilliamshealth.com/linksTB-500 spends way too much time in BPC-157's shadow. I wanted to fix that.This is my full TB-500 masterclass. I go deep on what this peptide actually does, and why it works so differently than BPC even though we lump them together as the Wolverine stack.First I clear up the confusion between TB-500 and thymosin beta-4, because most people have no idea what they're actually buying. Then I break down the mechanism in plain language. Think of TB-500 as the foreman on a job site, moving the right materials to the right injury at the right time.I cover who it's for, who should skip it, and my full dosing tiers from general recovery up to severe injury. We get into cycling, reconstitution, injection technique, and how to stack it with BPC, GHK, and the growth hormone peptides.I also answer the big questions. Is it legal? Will it cause cancer? Will it touch your hormones? Does it grow hair?If you want more from me, get on the email list and check out the Axion Collective. Both links are in my bio.Enjoy this one. I love TB-500.
Transcribe →Reader Mailbag 4 — Peptide Overdoses, GLP-1 Anhedonia & Hormone Truths
3w ago01:11:08Tap to summarizeTaylor and I are back for another Reader Mailbag. This one covers a lot of ground.We start with anhedonia on GLP-1s because the questions on this have been nonstop. People are experiencing it on Semaglutide, Tirzepatide, and Retatrutide and we break down why it happens, whether it is dose related, and what you can actually do about it.From there we get into the Reta and heart rate debate, Taylor's GLP rotation strategy, and whether the cardiovascular tradeoffs are actually worth worrying about.Then Taylor takes over for the hormone optimization section for young women in their twenties and thirties. Her personal story on this one is worth watching alone.We also cover accidental peptide overdoses, what to do when it happens, and finish with teen acne solutions using peptides and topicals.Submit your questions for the next episode at the link below.For research and entertainment purposes only.Links, cheatsheet, private group and more 👇https://hunterwilliamshealth.com/links
Transcribe →The May 2026 Q&A | Retatrutide, Testosterone, Autoimmune, and Beyond
4w ago00:59:01Tap to summarizeHey everybody, this is the May 2026 Q&A video, and we made it through a packed hour of your questions. I had so many submitted that I had to print them off and group them by category to get through them all.All My Links Here: https://hunterwilliamshealth.com/linksWe cover a lot of ground. GLPs and fertility, hunger on retatrutide, dopamine differences between Sema, Tirz, and Retta, GLP side effects and how to manage them. Then we move into hormones and HRT, including the right starting dose of testosterone, kisspeptin for fertility, progesterone dosing for women, and why so many doctors are starting guys way too low.From there we get into GH peptides and IGF cycling, my full injury healing stack, autoimmune protocols, cognitive stacks for studying, cosmetic questions, heart health, bone density, thyroid, and a long miscellaneous section covering rapamycin, MOTS-c, prostate peptides, traveling with peptides, and more.I also share the new AI chat tool I built that is trained only on my content. It is at chat.hunterwilliamshealth.com if you want to play with it.Thanks for submitting these. Keep them coming. See you in June.⚠️ For research and entertainment purposes only. ⚠️
Transcribe →The SS-31 Masterclass | Dosing, Stacking, Cycling, and Why It's A Top 3 Peptide
May 2600:42:11Tap to summarizeAll links here: https://hunterwilliamshealth.com/linksSS-31 continues to be one of my favorite peptides of all time, and the more data that comes out on it, the more I think every person over 25 has a use case for it.In this masterclass, I'm breaking down everything I know about SS-31. We cover what it actually does at the cellular level, why it's the first FDA-approved mitochondrial peptide, and why it works differently than almost every other peptide out there. No receptor binding. It goes inside your cells, binds to cardiolipin, and stabilizes the structure of your mitochondria.I walk through the three dosing tiers I use with people, my take on cycling, why I run SS-31 before MOTS-c, how to stack it with GLPs, GH peptides, and the healing peptides, and what to actually track when you're on it. I also cover the troubleshooting stuff people ask me about constantly. Why don't I feel anything? Should I cycle? What about the headaches in the first two weeks?If you're a clinician or just researching for yourself, this is the complete user's guide.For entertainment purposes only.Timestamps00:00 Intro01:00 What this masterclass covers03:18 Why SS-31 matters and what makes it different03:46 FDA approval and the Forzenity brand name04:50 Peptide foundations and how SS-31 is made05:52 The SS-31 sequence and the Seto-Schiller naming origin06:40 Mitochondria 101 and why ATP matters07:28 Mitochondrial dysfunction across chronic disease08:34 Cardiolipin, cristae, and Barth syndrome09:34 Why SS-31 is not a direct antioxidant10:46 How SS-31 actually works (the upstream Godfather effect)11:12 Why no receptor means no desensitization13:36 Who SS-31 is for (mid-30s, athletes, post-illness, metabolic dysfunction)14:24 Who should skip it15:34 The three-tier dosing ladder16:54 The FDA-approved 40mg dose and diminishing returns19:08 Dosing by goal (longevity, performance, recovery, healing)19:48 Cycling logic and the 8-12 week framework20:22 When to dose (morning vs night)21:24 What to expect and when (week-by-week timeline)22:20 Why cycle if it doesn't desensitize24:24 SS-31 before MOTS-c (the structural engineer vs operations manager)26:18 Reconstitution and injection technique28:22 What to track (subjective markers and biomarkers)29:18 Stacking with MOTS-c, Humanin, BPC, GH peptides, and GLPs31:28 Stacking for cognition and visceral fat32:26 Troubleshooting "I don't feel anything"33:54 Injection site reactions34:36 When to discontinue and the first-two-week headache window35:52 FAQ (legality, MitoQ comparison, oral routes, intranasal)36:54 Use cases (weight loss, long COVID, athletic performance, TRT, kids)37:54 Research grade vs pharmaceutical cost difference38:22 Future outlook (AMD, sarcopenia, SBT-272, oral bioavailability)40:30 Final thoughts and where SS-31 sits in the broader picture42:20 Closing
Transcribe →Peptides and Cancer | 20+ Studies the Critics Won't Show You
May 2200:30:08Tap to summarizeAll links here: https://hunterwilliamshealth.com/linksTimestamps:00:00 Intro01:00 Why I'm making this video04:00 The plan: peptides with direct anti-cancer evidence06:02 AOD-9604 and HGH Frag 176-19107:42 BPC-15709:54 DSIP (Delta Sleep Inducing Peptide)11:08 Epitalon12:30 Follistatin 34413:30 GHK-Cu14:36 Kisspeptin15:58 KPV17:18 LL-3718:46 Melanotan 219:58 MOTS-c21:12 Retatrutide22:34 Semaglutide23:40 SS-3124:38 Thymalin25:26 Thymosin Alpha-127:00 Tirzepatide27:30 VIP (Vasoactive Intestinal Peptide)28:06 Bottom line and closing thoughtsDescriptionIf you spend any time in the peptide social media world, you've heard it. "Peptides cause cancer." It's the easiest way to scare someone off something, and a lot of people do it without ever showing you a single study.So I went and pulled the studies. In this video I walk through every peptide on the popular research peptide list that actually has direct anti-cancer evidence in the published literature. Not theory. Not mechanism guesses. Actual studies in cells, animals, and in some cases, humans.You'll see what the research says about BPC-157, GHK-Cu, Epitalon, KPV, LL-37, Thymosin Alpha-1, MOTS-c, semaglutide, tirzepatide, retatrutide, and a handful more. Some of this evidence is strong. Some is preliminary. I'm honest about both.This is not medical advice and I'm not telling you peptides cure cancer. That's not what the data says and that's not what I'm claiming. What I am saying is that the next time someone hits you with a 60 second clip telling you peptides cause cancer, you'll have something more substantial to weigh it against.All study links below.📚 Studies Referenced (in order of appearance)AOD-9604 / HGH Frag 176-191 https://pmc.ncbi.nlm.nih.gov/articles/PMC9249349/BPC-157 https://journals.lww.com/melanomaresearch/citation/2004/08000/bpc_157_inhibits_cell_growth_and_vegf_signalling.50.aspx https://pubmed.ncbi.nlm.nih.gov/29886825/DSIPhttps://pubmed.ncbi.nlm.nih.gov/12782416/Epitalon https://pubmed.ncbi.nlm.nih.gov/14501183/ https://pubmed.ncbi.nlm.nih.gov/12209581/ https://pubmed.ncbi.nlm.nih.gov/12049808/Follistatin 344 https://pmc.ncbi.nlm.nih.gov/articles/PMC9633376/GHK-Cu https://neoplasiaresearch.com/index.php/jao/article/view/217 https://www.lidsen.com/journals/genetics/genetics-05-02-128Kisspeptin https://pubmed.ncbi.nlm.nih.gov/8944003/ https://pubmed.ncbi.nlm.nih.gov/28944853/KPV https://pmc.ncbi.nlm.nih.gov/articles/PMC4957955/LL-37 https://pmc.ncbi.nlm.nih.gov/articles/PMC3910284/ https://pmc.ncbi.nlm.nih.gov/articles/PMC3659029/Melanotan 2 https://pmc.ncbi.nlm.nih.gov/articles/PMC7013727/MOTS-c https://pmc.ncbi.nlm.nih.gov/articles/PMC11578304/Retatrutide https://pmc.ncbi.nlm.nih.gov/articles/PMC11908972/Semaglutide https://pmc.ncbi.nlm.nih.gov/articles/PMC11227080/ https://pubmed.ncbi.nlm.nih.gov/38683947/ https://pmc.ncbi.nlm.nih.gov/articles/PMC12587238/SS-31 https://pmc.ncbi.nlm.nih.gov/articles/PMC7923037/Thymalin https://pubmed.ncbi.nlm.nih.gov/6752596/ https://pubmed.ncbi.nlm.nih.gov/29797130/Thymosin Alpha-1 https://pubmed.ncbi.nlm.nih.gov/8652276/ https://pmc.ncbi.nlm.nih.gov/articles/PMC2748379/ https://pubmed.ncbi.nlm.nih.gov/20194853/ https://pubmed.ncbi.nlm.nih.gov/27900029/ https://pubmed.ncbi.nlm.nih.gov/30063847/Tirzepatide https://www.biorxiv.org/content/10.1101/2024.01.20.576484v1 https://aacrjournals.org/cancerres/article/84/6_Supplement/2188/738498/Abstract-2188-Tirzepatide-treatment-restoresVIPhttps://pmc.ncbi.nlm.nih.gov/articles/PMC6317926/
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